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| 1 | Research Progress on Analysis and Detection Techniques of Veterinary Drug Residues in Animal Foods显示文摘As an important guarantee for the prevention and control of animal diseases,veterinary drugs have important functions in improving animal production performance and product quality and maintaining ecological balance.They are an important guarantee for the healthy development of animal husbandry,food safety and public health.However,the irrational use and abuse of veterinary drugs and feed pharmaceutical additives are widespread,causing harmful substances in animal foods and damage to human health,and threatening the sustainable development of the environment and animal husbandry as well.In order to ensure human health,it is urgent to develop a simple,rapid,high-sensitivity,high-throughput and low-cost veterinary drug residue detection technology.In this paper,the sample pretreatment methods and detection techniques for the analysis of veterinary drug residues in animal foods were reviewed. | Bing LI Xuzheng ZHOU Fusheng CHENG Xiaojuan WEI Weiwei Wang Jiyu ZHANG | 2019 | Agricultural Biotechnology2019，8，5： | 1 |
| 2 | Acute Toxicity of Oxyclozanide Suspension in Mice by Oral Administration显示文摘The safety of oxyclozanide suspension was preliminarily evaluated through acute toxicity test in mice. Administration dose,formal trial grouping and group interval were determined in pre-trial using incremental method. Formal test was performed using simplified karber's method. Changes in sign of mice after administration were observed; the mortality rate was statistically calculated,and the time of death was recorded; the median lethal dose( LD_(50)) and 95% confidence limit of oxyclozanide suspension were calculated. The results showed the LD_(50) of oxyclozanide suspension in mice by oral administration was 1. 679 g/kg,and the95% confidence interval was 1. 439-1. 947 g/kg. According to toxicity grading of chemicals,oxyclozanide suspension was low toxic substance. | Zhang Jili Zhang Jiyu Si Hongfei Cheng Fusheng Zhou Xuzheng Li Bing | 2016 | Animal Husbandry and Feed Science2016，8，6： | 0 |
| 3 | Preparation of Compound Ban Huang Oral Liquid显示文摘[Objectives] To determine the optimal preparation process of compound Ban Huang oral liquid. [Methods] Orthogonal test and other methods were used to optimize the preparation conditions of compound Ban Huang oral liquid. [Results] The optimal conditions determined were as follows: soaking for 12 h,decocting twice with 2 h per time,concentrating filtrate to 1. 18-1. 25 g/m L at 80 ℃,ethanol precipitating twice with ethanol contents of 600 and 750 ml/L,standing for 24 h. [Conclusions] The optimized preparation process is simple,feasible and stable,and can be used for preparing compound Ban Huang oral liquid. | Bing LI Jianrong NIU Xuzheng ZHOU Jianyong LI Xiaojuan WEI Yajun YANG Xiwang LIU Jiyu ZHANG | 2019 | Medicinal Plant2019，10，3： | 0 |
| 4 | K-PD Model and Its Application in Research of Veterinary Antimicrobials显示文摘With the development of the PK-PD model,its application in veterinary antimicrobials has also received great attention.This paper expounded the theory of PK-PD model,and made a brief analysis of the dosing regimens of various antibiotics according to the parameters of antimicrobial drugs,in order to optimize the clinical drug delivery plan and promote the rational use of clinical antibiotics. | Bing LI Jiyu ZHANG Jianyong LI Yajun YANG Xuzheng ZHOU Jianrong NIU Xiaojuan WEI Jinshan LI | 2019 | Agricultural Biotechnology2019，8，4： | 0 |
| 5 | The Mechanism Behind Urban Population Growth and Shrinkage from the Perspective of Urban Network Externalities显示文摘Urban shrinkage is a global phenomenon,and it will coexist with urban growth for many years.At the same time,the network connection between cities continuously improved due to the construction of the transportation and information networks.However,the relationship between urban network externalities and urban population growth/shrinkage remains unclear.Therefore,based on high-speed railway(HSR)flow data,a spatial econometric model is used to explore the mechanism behind urban population growth and shrinkage from the perspective of network externalities in China.The results indicate that:1)the urban network experiences a certain clubbing effect.Growing cities that are strongly connected are concentrated along China’s main railway lines and the southeastern coastal areas,while shrinking cities that are weakly connected are distributed at the periphery of the network.2)Moreover,the network externality disregards spatial distance and together with the agglomeration externality influences the growth and shrinking of cities.3)Urban economic development still promotes the development of Chinese cities.However,the improvement of the urban economy has a negative cross-regional spillover effect on neighboring cities due to urban competition.4)Lastly,Local spillovers of urban network externalities are positive,while cross-regional ones are negative.Consequently,the government needs to promote the construction of multi-dimensional network connections between cities to promote cities’sustainable development.This study reveals the relationship between urban network externalities and urban development,enriches the theories of network externalities and urban growth/shrinkage,and provides a reference for regional coordinated development. | ZHOU Ying ZHENG Wensheng WANG Xiaofang XIONG Yajun WANG Xuzheng | 2023 | Chinese Geographical Science2023，33，2： | 0 |
| 6 | Study on Method for Determination of Artemether Content in New Artemether Injection显示文摘This study was conducted to establish a high performance liquid chromatography( HPLC) method for the determination of artemether in the artemether injection using Hypersil ODS C18 chromatographic column( 5 μm,4. 6 mm × 150 mm). Mobile phase,column temperature,flow rate and detection wavelength were optimized. Acetonitrile-water-tetrahydrofuran( 62∶ 37∶ 1,V/V) was selected as the mobile phase,and the HPLC was performed with column temperature at30 ℃ and the flow rate at 1. 0 ml/min; and the detection wavelength was set at 216 nm. The HPLC detection system of artemether had good suitability. The linearity was good in 100-800 μg/ml concentration range,and the regression equation was y = 302. 36 x-682. 02,R2= 0. 999 8. The overall average recovery was97. 58%,and the RSD was 1. 58%. Three batches of artemether injection samples were determined by the method,showing RSD of 1. 42%. The method could be used for the detection of artemether content in artemether injection. | Bing LI Sihan WANG Xuzheng ZHOU Jiyu ZHANG | 2018 | Agricultural Biotechnology2018，7，3： | 0 |
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