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1ConservativeapproachinPeutz-JeghersSyndrome:Single-balloon enteroscopyandsmallbowelpolypectomy显示文摘AIM: To assess the usefulness of the balloon assisted enteroscopy in preventing surgical intervention in pa-tients with Peutz-Jeghers syndrome (PJS) having a small bowel large polyps. METHODS: Seven consecutive asymptomatic pts(age 15-38 years) with PJS have been collected; six under-went polypectomy using single balloon enteroscopy(Olympus SIF Q180) with antegrade approach using push and pull technique. SBE system consists of the SIF-Q180 enteroscope, an overtube balloon control unit(OBCU Olympus Balloon Control Unit) and a dispos-able silicone splinting tube with balloon(ST-SB1). All procedures were performed under general anesthesia. Previously all pts received wireless capsule endos-copy(WCE). Prophylactic polypectomy was reservedmainly in pts who had polyps > 15 mm in diameter. The balloon is inflated and deflated by a balloon control unit with a safety pressure setting range from-6.0 kPa to +5.4 kPa. Informed consent has been obtained from pts or parents for each procedure.RESULTS: Six pts underwent polypectomy of small bowel polyps; in 5 pts a large polyp > 15 mm(range 20-50 mm in diameter) was resected; in 1 patient with WCE negative, SBE was performed for previous surgi-cal resection of gastrointestinal stromal tumors. In 2 pts endoscopic clips were placed due to a polypectomy. No surgical complication have been reported. SBE with resection of small bowel large polyps in PJS pts was useful to avoid gastrointestinal bleeding and emergency laparotomy due to intestinal intussuscep-tions. No gastrointestinal tumors were found in sub-sequent enteroscopic surveillance in all seven pts. In order surveillance, all pts received WCE, upper en-doscopy, ileocolonoscopy every 2 years. No pts had extraintestinal malignant lesions. SBE was performed when WCE was positive for significant polyps(> 15 mm).CONCLUSION: The effective of prophylactic polyp-ectomy of small bowel large polyps(> 15 mm) could be the first line treatment for conservative approach in management of PJS patients.Torroni F Romeo E Rea F De Angelis P Foschia F Faraci S Federici di Abriola G Contini AC Caldaro T Dall’Oglio L 2014World Journal of Gastrointestinal Endoscopy2014,6,7:7
2螺内酯与可乐定作为难治性高血压第4种治疗药物的比较:难治性高血压的最佳治疗随机研究显示文摘该研究旨在通过一个多中心随机试验对作为难治性高血压患者的第4种治疗药物的螺内酯与可乐定进行比较。采用药丸计数评估药物治疗依从性。难治性高血压患者(定义为包括1种利尿剂在内的3种药物治疗12周,诊室及动态血压监测血压仍未控制)随机给予螺内酯(12.5~50 mg/d)或可乐定(0.1~0.3mg,2次/d)继续治疗12周。Krieger EM Drager LF Giorgi DMA Pereira AC Barreto-Filho JAS Nogueira AR Mill JG Lotufo PA Amodeo C Batista MC Bodanese LC Carvalho ACC Castro I Chaves H Costa EAS Feitosa GS Franco RJS Fuchs FD Guimarāes AC Jardim PC Machado CA Magalhāes ME Mion D Jr Nascimento RM Nobre F Nóbrega AC Ribeiro ALP Rodrigues-Sobrinho CR Sanjuliani AF Teixeira MDCB Krieger JE ReHOT Investigators 赵狄 练桂丽 2018中华高血压杂志2018,26,3:7
3健康领域的文化能力显示文摘1背景 尽管人类对其他社会的兴趣纵贯历史的各个阶段,但是检验不同文化概念对人类健康实践的影响从20世纪才开始,当时是伴随着长期的人类学田野调查产生的,这些田野调查揭露了不同文化之间相关卫生实践的多样性、复杂性和连续性。Napier A D Ancarno C Butler B Calabrese j Chater A Chatterjee H Guesnet F Home R Jacyna S Jadhav S Macdonald A Neuendorf U Parkhurst A Reynolds R Scambler G Shamdasani S Smith S Z Stougaard-Nielsen J Thomson L Tyler N Volkmann A M Walker T Watson J Williams AC Willott C Wilson J Woolf K 2016中国卫生政策研究2016,9,2:5
4卒中介入治疗培训指南:国际多学会共识文件显示文摘1背景 缺血性卒中是全球人口死亡和残疾的首要原因。很多急性大血管闭塞(emergent large vesselocclusion,ELVO)患者都会遗留长期残疾。事实上,这些颅内大动脉闭塞经常会导致大面积脑损伤,进而造成患者死亡或严重致残。Lavine SD Cockroft K Hoh B Bambakidis N Khalessi AA Woo H Riina H Siddiqui A Hirsch JA Chong W Rice H Wenderoth J Mitchell P Coulthard A Signh TJ Phatorous C Khangure M Klurfan P ter Brugge K Iancu D Gunnarsson T Pongpech S Rodesch G Soderman M Taylor A Krings T Orbach D Picard L Suh DC Zheng HQ Jansen O Muto M Szikora I Pierot L Brouwer P Gralla J Renowden S Andersson T Fiehler J Turjman F White P Januel AC Spelle L Kulcsar Z Chapot R Biondi A Dima S Taschner C Szajner M Krajina A Sakai N Matsumaru Y Yoshknura S Ezura M Fujinaka T Iihara K Ishii A Higashi T Hirohata M Hyodo A Ito Y Kawanishi M Kiyosue H Kobayashi E Kobayashi S Kuwayama N Matsumoto Y Miyachi S Murayama Y Nagata I Nakahara I Nemoto S Niimi Y Oishi H Satomi J Satow T Sugiu K Tanaka M Terada T Yamagami H Diaz O Lylyk P Jayaraman MV Patsalides A Gandhi CD Lee SK Abruzzo T Albani B Ansari SA Arthur AS Baxter BW Bulsara KR Chen M Almandoz JE Fraser JF Heck DV Hetts SW Hussain MS Klucznik RP Leslie-Mawzi TM Mack WJ McTaggart RA Meyers PM Mocco J Prestigiacomo CA Pride GL Rasmussen PA Starke RM Sunenshine PJ Tarr RW Frei DF Pabo M Nogueira RG Zaidat OO Jovin T Linfante I Yavagal D Liebeskind D Novakovic R Pongpech S 许岩 孙瑞 郭芮兵 2017国际脑血管病杂志2017,25,5:2
5A sham-controlled trial of a 5-day course of repetitive transcranial magnetic stimulation of the unaffected hemisphere in stroke patients显示文摘Fregni F Boggio PS Valle AC 2006Stroke2006,37,8:1
6Right ventricular function assessed by two-dimensional strain and tissue Doppler echocardiography in patients with pulmonary arterial hypertension and effect of vasodilator therapy显示文摘Borges AC Knebel F Eddicks S 2006Am J Cardiol2006,98,4:1
7Angiotensin II induces connective tissue growth factor and collagen I expression via transforming growth factor-beta-dependent and -independent Smad pathways: the role of Smad3 显示文摘Yang F Chung AC Huang XR 2009Hypertension2009,54,4:1
8Maturation in vitro of human oocytes from unstimulatedcycles : selection of the optimal day for ovum retrieval based on follicular size 显示文摘Cobo AC Requena A Neuspiller F 1999Hum Reprod1999,14,7:1
9Positional enhancer-blocking activity of the chickenβ-globin 5'HS4 insulators in transiently transfected cells显示文摘Recillas-Targa F Bell AC Felsenfeld G 1999Proc Nail Acad Sci USA1999,96,14:1
10The murine stanniocalcin 1 gene is not essential for growth and development 显示文摘Chang AC Cha J Koentgen F 2005Mol Cell Biol2005,25,10:1
11Increased oxidativestress as a mechanism for decreased BDNF levels in acute manicepisodes显示文摘Kapczinski F Frey BN Andreazza AC 2008Rev Bras Psiquiatr2008,30,3:1
12Diagnostic accuracy of computed tomography angiography in patients after bypass grafting: comparison with invasive coronary angiography 显示文摘Weustink AC Nieman K Pugliese F 2009JACC Cardiovasc Imaging2009,2,:1
13Metabolic basis of HIV-lipodystrophy syndrome显示文摘Sekhar RV Jahoor F White AC 2002Am J Physiol Endocri- nol Metab2002,283,2:1
14Comparison of aortic root dimensions and geometries before and after transcatheter aortic valve implantation by 2-and 3-dimensional transesophageal echocardiography and multislice computed tomography显示文摘Ng AC Delgado V Van der Kley F 0,,01:1
15Antimicrobial re- sistance among urinary tract infection (UTI) isolates in Eu- rope: Results from the SENTRY Antimicrobial Surveillance Program 1997 显示文摘FLUIT AC JONES ME SCHMITZ F J 2000Antonie Van Leeuwenhoek2000,77,2:1
16Characterization of the interaction between DARPP-32 and protein phosphatase 1 (PP-1):DARPP-32 peptides antagonize the interaction of PP-1 with binding proteins显示文摘Kwon YG Huang HB Desdouits F Girault JA Greengard P Nairn AC 1997Proc Natl Acad Sci USA1997,94,8:1
17Reversion of Multidrug Resistance with Polyalkylcyanoacrylate Nanoparticles:Towards a Mechanism of Action显示文摘AC de Verdiere Dubernet C Nemati F 1997Br J Cancer1997,76,1:1
18Characterizing the functionality of recombinant T-cell receptors in vitro: a pMHC tetramer based approach显示文摘Tissot AC Pecorari F Pluckthun A 2000J Immunol Methods2000,236,12:1
19Antifungal activi-ty of local anesthetics against Candida species显示文摘Pina-Vaz C Rodrigues AC Sansonelty F 2000Infect Dis ObstetGynecol2000,8,1:1
20Different strains of Propionibacterium aches modulate differently the cutaneous innate immunity显示文摘Jasson F Nagy I Knol AC 2013Exp Der- matol2013,22,9:1
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