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| 1 | Lamivudine prophylaxis of liver allograft HBV reinfection in HBV related cirrhotic patients after liver transplantation显示文摘BACKGROUND: Liver allograft hepatitis B virus (HBV) reinfection and hepatitis B (HB) recurrence jeopardize the long-term survival of recipient and liver allograft. Lamivu- dine has been referred as a novel antiviral agent against HBV in HBV cirrhotic patients even in liver transplantation setting. We assessed the prophylatic effect of lamivudine on liver allograft HBV reinfection and clarified the dynamic changes of HBV markers in HBV related decompensated liver cirrhosis after liver transplantation. METHODS: Twenty-five recipients were divided into three groups: HBV active replication group (15 recipients), HBV inactive replication group (7), and control group (3). 100 mg/d lamivudine was administered preoperatively except in the control group. The HBV markers of serial sera and liver biopsy samples of the 25 recipients were evaluated re- gularly with enzyme-linked radioimmunoassay, HBV DNA fluorecent quantitative assay, immunohistochemical stain- ing , labelled streptavidin biotin ( LSAB) and digoxin la- belled HBV DNA hybridization in situ. The dynamic alter- nation of HBV markers under lamivudine prophylaxis was observed. RESULTS: In the HBV active replication group who had received lamivudine 2 weeks before liver transplantation, serum HBV DNA positive converted to negative by 80%. HBsAg of all recipients disappeared after liver transplanta- tion , but corresponding antibodies of HBV appeared within one week after the operation. HBsAb 9/15, HBcAb 13/15 and HBeAb 11/15 appeared and subsided gradually within 24 weeks. HBV DNA in sera was kept negative; HBsAg, HBcAg and HBV DNA hybridization in situ of liver biopsy samples remained negative after use of lamivudine. Ten of the 15 recipients showed clearance of HBV, and per se HBV markers were undetectable both in serum and liver bi- opsy samples between 12 to 44 weeks (24 weeks on ave- rage). The 1-, 2-year survival rates were 83% in this group. Two of the 15 recipients developed HBV allograft reinfection or recurrence of hepatitis 2 years after lamivudi- ne monoprophylaxis (2/15, 13.3%). In the HBV inactive replication group, the outcome was similar to that of the HBV active group. The HBV antibody frequency was HBs- Ab 4/7, HBcAb 6/7, and HBeAb 2/7. Three of 7 recipients showed HBV clearance both in sera and liver biopsy sam- ples , whereas in the control group all 3 recipients developed HBV allograft reinfection and recurrent hepatitis 8, 10, 12 months postoperatively; one of them died of fibrosing cho- lestatic hepatitis, and the remaining 2 recovered after addi- tional lamivudine therapy. The overall allograft reinfection rate was 9.1% (2/22) and the overall 1-, 2-year survival rates were 87%) in the lamivudine prophylaxis group. CONCLUSIONS: Lamivudine prophylaxis can prevent ef- fectively liver allograft from HBV reinfection in patients with HBV-related decompensated liver cirrhosis even in HBV active replication recipient after liver transplantation. Its long-term outcome remains to be studied. | Shi-Chun Lu, Lu-Nan Yan, Bo Li, Tian-Fu Wen, Ji-Chun Zhao, Nan-Sheng Cheng, Chong Liu, Jun Liu, Xiao-Bo Wang, Xiao-Dong Li, Shan Qin, Lian-Shan Zhao, Bin-Jun Lei and Xiu-Hui Zhang Chengdu, China Department of Surgery Viral Hepa- titis Research Center Department of Pathology , West China Hospital, Sichuan University, Cheng- du 610041 , China | 2004 | Hepatobiliary & Pancreatic Diseases International2004，3，1： | 9 |
| 2 | FRACTAL RESEARCH ON CRACKS PROPAGATION OF GAS PIPELINE X52 STEEL WELDING LINE UNDER HYDROGEN ENVIRONMENT显示文摘Based on the theory of hydrogen enhanced localized plasticity of the hydrogen induced cracking and considered the effect of residual stress produced by eliminated stress heat treatment, a fractal model of hydrogen induced cinching was presented, and a relationship among the effective surface energy (H), fractal dimension D and stress intensity factor of hydrogen induced cracking, KIH, for welding pipeline under hydrogen environment was set up, from which the relationship of D and KISCC is obtained. The model was verified experimentally to be correct. | S.H. Dong , Y.M. Lu, Y. Zhang and Q. Wu (Mechanics Electronic Department, University of Petroleum, Beijing 102200, China) (Department of Material Physics, University of Science and Technology Beijing, Beijing 100083, China) (Yan Shan University, Qinhuangd | 2001 | Acta Metallurgica Sinica(English Letters)2001，14，3： | 5 |
| 3 | Research on the Characteristics of Hot Deformation in BT20 Titanium alloy and Its Optimum Spinning Temperature Range显示文摘Hot compression tests were conducted on a Gleeble-1500 simulator to investigate the hot deformation behavior of BT20 Ti alloy (Ti-6Al-2Zr-1Mo-1V) in the temperature range from 550 to 1000℃ at constant strain rate in the range of 0.01~1 s-1, and then the optimum spinning temperature range was determined. Moreover, tube spinning experiments were executed to verify the reasonability of the optimum temperature range. The results show that the flow stress declines gradually with increasing deformation temperature and decreasing strain rate. In α+β phase region the dynamic recrystallization is the main softening mechanism and in β phase region the hot deformation softening is controlled by dynamic recovery. In α+βphase region with reducing strain rate dynamic recrystallization is fully developed. The optimum temperature of hot spinning is 850~900℃ and that of warm spinning is 600~650℃.Meanwhile, at the temperature above 600℃ tubular workpieces of BT20 Ti alloy have been spun without surface cracks and microstructure inhomogeneity, which proves that the optimum spinning temperature range obtained through hot compression experiments is reasonable. | Wenchen XU+, Debin SHAN, Yan LU and Chunfeng LISchool of Materials Science and Engineering, Harbin Institute of Technology, Harbin 150001, China | 2005 | Journal of Materials Science & Technology2005，21，6： | 2 |
| 4 | Shape-controlled synthesis o{ TiO2 hollow structures and their application in lithium batteries 显示文摘 | Wang Yong Su Xiaowen and Lu Shan | 2012 | Journal of Materials Chemistry2012，22，5： | 1 |
| 5 | MORE FACILE SYNTHESES TO THE SEX PHEROMONE COMPONENTS OF THE WINTER MOTH(OPEROPHTERABRUMATAL.(LEPIDOPTERA:GEOMETRIDAE):(3Z,6Z,9Z)-3,6,9-NONADECATRIENE,(6Z,9Z)-6,9-NONADECADIENE显示文摘MOREFACILESYNTHESESTOTHESEXPHEROMONECOMPONENTSOFTHEWINTERMOTH(OPEROPHTERABRUMATAL.(LEPIDOPTERA:GEOMETRIDAE):(3Z,6Z,9Z)-3,6,9-... | Bao Ming Xu Liang Fn HUANG Shu Xiang SHAN and Xue You ZHU(Departmnt of Biotechnoleqy, Sichuan University, Chengdu 610064)(Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences,345 Linqling Lu, Shanghai Z00032)(Present address:Chemical Eng | 1994 | Chinese Chemical Letters1994，5，1： | 1 |
| 6 | The muscle-specific microRNAs miR-1 and miR-133 produce opposing effects on apoptosis by targeting HSP60, HSP70 and caspase-9 in cardiomyocytes显示文摘 | Chaoqian Xu Yanjie Lu Zhenwei Pan Wenfeng Chu Xiaobin Luo Huixian Lin Jiening Xiao Hongli Shan Zhiguo Wang and Baofeng Yang | | Journal of Cell Science0，120，17： | 1 |
| 7 | NEW TYPE OF DUAL BEM AND GREEN'S-FUNCTION-LIBRARY STRATEGY FOR FRACTURE ANALYSIS IN COMPLEX STRUCTURES显示文摘A new type of dual boundary integral equations(DBIE)is presented first,through which,asmaller system of equations needs to be solved in fracture analysis.Then a non-conforming crack tip elementin two-dimensional problems is proposed.The exact formula for the hypersingular integral over the non-con-forming crack tip element is given next.By virtue of Green’s-function-library strategy,a series of stress in-tensity factors(SIF)of different crack orientations,locations and/or sizes in a complicated structure can beobtained easily and efficiently.Finally,several examples of fracture analysis in two dimensions are given todemonstrate the accuracy and efficiency of the method proposed. | Lu Shan Huang Qiqing (Department of Aeroengine and Thermal Power Engineering,Northwestern Polytechnic University,Xi’an 710072,China) | 2000 | Acta Mechanica Solida Sinica2000，13，4： | 1 |
| 8 | Hot spinning of cylindrical workpieces of TA15 titanium alloy显示文摘In order to form large-diameter thin-wall cylindrical workpieces of TA15 titanium alloy,tube hot spinning experiments of the alloy were conducted on a CNC hot spinning machine.The causes of some forming defects occuring in hot spinning,such as crack,pileup,bulge and corrugation,were analyzed and the corresponding measures were put forward to avoid spinning defects,based on which a proper process scheme of hot spinning of TA15 alloy was obtained and the large-diameter and thin-walled cylindrical workpieces were formed with good quality.The results show that spinning temperature has distinct influence on forming quality of spun workpieces.The range of spinning temperature determines the spinnability of titanium alloy and the ununiformity of temperature distribution near the deformation zone leads to the formation of bulge.The reasonable heating method is that the deforming region is heated to the optimum temperature range of 600-700 ℃,the deformed region is heated continuously and a certain length of undeformed region is preheated.With the thickness-to-diameter ratio(t/D) of spun workpiece reducing to certain value(t/D<1%),surface bulge and corrugation is rather easier to come into being,which could be controlled through restraining diameter growth and employing smaller reduction rate and lower temperature in the optimum spinning temperature range. | XU Wenchen,SHAN Debin,YANG Guoping,CHEN Yu,LU Yan,and KANG Dachang School of Materials Science and Engineering,Harbin Institute of Technology,Harbin 150001,China | 2007 | Rare Metals2007，26，S1： | 1 |
| 9 | Key Problems of Cold Power Spinning of Ti-15-3 Alloy显示文摘The key problems of cold power spinning of Ti-15-3 alloy are studied. Reasonable billet preparation methods are presented to improve crystal structure and avoid crack of billet. Influences of original wall thickness, reduction rate and feed rate on expanding in diameter are analyzed and some methods to prevent expanding in diameter are given. | Debin SHAN Yan LU and Ping LI School of Materials Science and Engineering, Harbin institute of Thchnology, Harbin 150001, China Yi XU Institute of Metal Research, Chinese Academy of Sciences, Shenyang 110015, China | 2001 | Journal of Materials Science & Technology2001，17，1： | 1 |
| 10 | Determination of Atom Number of Fission Product ^(126)Sn by γ-ray Spectrometry显示文摘126Sn is a long-lived beta emitting radionuclide with a half-life of (2.35±0.07)×105 years[1]. Artificially produced 126Sn has entered our environment through nuclear weapons testing and released from reprocessing plants and may locally lead to strongly enhanced 126Sn concentrations. So the | SHEN Hong-tao, HE Ming, Zhang Da-wei1, HUANG Chun-tang1, WANG Wei, LI Chao-li, WANG Xiang-gao, SHI Guo-zhu1, WU Shao-lei, GONG Jie, LU Li-yan, HE Guo-zhu, WU Shao-yong, JIANG Shan (1. College of Physics Science and Technology, Guangxi University, Nanning 530004, China) | 2008 | Annual Report of China Institute of Atomic Energy2008，，1： | 0 |
| 11 | CATALYTIC ASYMMETRIC EPOXIDATION OF a-FURFURYLAMINE IN THE PRESENCE OF MOLECULAR SIEVE AND CaH_2显示文摘CATALYTICASYMMETRICEPOXIDATIONOFa-FURFURYLAMINEINTHEPRESENCEOFMOLECULARSIEVEANDCaH_2￥ZhiHutLU;XueYouZHUandWeiShanZHOU(Shangha?.. | Zhi Hut LU Xue You ZHU and Wei Shan ZHOU(Shanghai Institute of Organic Chemistry ,Chinese Academ of Sciences.354 Fengling Lu. Shanghai 200032)(Department of Bio-engineering Sichuan University. Chengdu 610064) | 1994 | Chinese Chemical Letters1994，5，7： | 0 |
| 12 | THE UNIQUENESS OF LIMIT CYCLE AND CRITICAL POINT FOR A CLASS OF CUBIC SYSTEM显示文摘In this paper,we consider an accompany system concerning some class of cubic system. We then prove that the system has at most one limit cycle. Finally,we obtain the topological structure of both the critical points at infinity and the singular points lying on invariant lines. | Jin Shan,Lu Shiping(College of Math. and Computer Science,Anhui Normal University,Wuhu 241000,Anhui) | 2008 | Annals of Differential Equations2008，24，2： | 0 |
| 13 | Experimental Study on Production of ^(126)Sn Negative Ions for AMS Measurement显示文摘Many isobaric nuclides of radionuclides can not form negative ions or stable negative ions, which can be helpful to effectively eliminate the interference from the isobaric nuclides. In AMS measurements, | SHEN Hong-tao, HE Ming, WANG Wei, LI Chao-li, WANG Xiang-gao, ZHANG Da-wei1, SHI Guo-zhu1, HUANG Chun-tang1, WU Shao-lei, GONG Jie, LU Li-yan, HE Guo-zhu, WU Shao-yong, JIANG Shan (1. College of Physics Science and Technology, Guangxi University, Nanning 530004, China) | 2008 | Annual Report of China Institute of Atomic Energy2008，，1： | 0 |
| 14 | ^(236)U and Its Measurement With Accelerator Mass Spectrometry显示文摘236U natural occurring isotopic abundance, 236U/238U atom number ratio, is about 10-14. Therefore, 236U is potentially useful as a ‘fingerprint’ for the presence in the environment or nuclear waste | WANG Xiang-gao, HE Ming, WANG Wei, LI Chao-li, SHI Guo-zhu1, ZHANG Da-wei1, HUANG Chun-tang1, SHEN Hong-tao, GONG Jie, LU Li-yuan, WU Shao-lei, HE Guo-zhu, WU Shao-yong, JIANG Shan (1. College of Physics Science and Technology, Guangxi University, Nanning 530004, China) | 2008 | Annual Report of China Institute of Atomic Energy2008，，1： | 0 |
| 15 | Chemical Form of Selection and Preparation on ^(79)Se-AMS Measurement Samples显示文摘The AMS team in CIAE developed the method for measuring 79Se via AMS, which was based on extracting molecular negative ion form SeO2-. The sensitivity is improved to be better than 1. | WANG Wei, HE Ming, LU Li-yan, HUANG Chun-tang1, LI Chao-li, WU Shao-yong, JIANG Shan (1. Physics Science and Engineering Technology Department, Guangxi University, Nanning 530004, China) | 2008 | Annual Report of China Institute of Atomic Energy2008，，1： | 0 |
| 16 | CORROSION INHIBITION OF STEARIC ACID LANGMUIR-BLODGETT MONOLAYERS ON IRON显示文摘The Langmuir-Blodgett (LB) technique was used for the first time to study inhibition mechanism. Stearic acid Langmuir-Blodgett (SALB) monolayers showed a good inhibition effect on iron corrosion in neutral environment and the inhibition is mainly based on the blocking effect. | Wei XING Yi Bin SHAN Du GUO Tian Hong LU** and Shi Ouan XI** Laboratory of Electroanaiytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022 | 1993 | Chinese Chemical Letters1993，4，1： | 0 |
| 17 | Study of Effects of Cordyceps sinensis on Natural Killer Cells in Leukemia显示文摘StudyofEffectsofCordycepssinensisonNaturalKillerCellsinLeukemiaLiuChao(刘超);LuShan(卢珊);JiMei-rong(姬美蓉)andXieYi(谢毅);(Hematology... | Liu Chao (刘超) Lu Shan(卢珊) Ji Mei-rong (姬美蓉)and Xie Yi(谢毅) (Hematology Research Unit, Huashan Hospital, Shanghai Medical University. Shanghai)(200040) | 1995 | Chinese Journal of Integrative Medicine1995，1，1： | 0 |
| 18 | PREPARATION AND CHARACTERIZATON OF MICROPOROUS CATALYTIC MATERIALS WITH NARROW PORE DISTRIBUTION AND HIGHLY DISPERSED PALLADIUM显示文摘PREPARATIONANDCHARACTERIZATONOFMICROPOROUSCATALYTICMATERIALSWITHNARROWPOREDISTRIBUTIONANDHIGHLYDISPERSEDPALLADIUM￥AnWuLi;GuoX... | An Wu Li Guo Xing XIONG Hong Bin ZHAO Jing Hua Gu Shi Shan SHENG Wei CUI and Lu Bin ZHENG(State Key Laboratory of Catalysis, Dalian Institute of Chemical Physics,Chinese Academy of Sciences, Dalian 116023) | 1996 | Chinese Chemical Letters1996，7，2： | 0 |
| 19 | CRYSTAL STRUCTURE OF DI - NITRATOBIS(ETHYLCAPROLACTAM)URANYL(Ⅱ) UO_2[CH_2(CH_2)_4CONC_2H_5]_2(NO_3)_2显示文摘The crystal structure of Di-nitratobis(ethylcaprolactam)uranyl(Ⅱ) UO2[CH2(CH2)4CONC2H5]2(NO3)2 was established by a single-crystal X-ray diffraction study.It is triclinie, space group P1, with a=7.171(2), b=8.655(3), c=10.182(5)A, α=78.27(3), β=70.63(3), γ=81.76(3)°, V=581.7(4)A3, Z=l, Dc=1.94 g.cm-3.Final R value is 0.0218.The result reveals that uranyl ion is coordinated to six oxygen atoms, two of them are from two carbonyl groups of ethylcaprolactam and the other four are from two nitrate groups. | Zheng Bai CAO~a, Han Zhang WANG~(a*), Zhen Rong LU~b, Li Min ZHU~a, Jian Sheng GU~a, Song Shan GUO~a a. Dept. of Chem. Suzhou University, Suzhou, 215006 b. The Central Laboratory, Suzhou University, Suzhou, 215006 Kai Bei YU Chengdu Center of Anal, and Determ. Academic Sinica, Chengdu, 610051 | 1992 | Chinese Chemical Letters1992，3，3： | 0 |
| 20 | Bacteriological Analysis of the Digestive Tube of the Mud Snail (Bullacta exarata Philippi) and Its Rearing Shoal显示文摘The bacterial flora in the digestive tube of Bullacta exarata Philippi and its rearing shoal were investigated. A total of 157 strains of heterotrophic bacteria, isolated from crop, stomach intestine and other parts of the digestive tube, mainly belong to the genera Photobacterium, Bacillus, Pseudomonas Vibrio and some genera of the family Enterobacteriaceae. There are significantly more varieties of bacteria in crop than in stomach and intestine. A total of 173 strains of bacteria were isolated from the rearing shoal, belonging to 13 genera. The 5 predominant genera, such as Bacillus and Photobacterium, are the same as those in the digestive tube, but greatly differ in percentages. The number of heterotrophic bacteria and Vibrio in rearing shoal change in line with the alteration of the temperature, and are significantly affected by the use of pesticides. | WANG Guoliang, ZHENG Tianlun *, LU Tongxia, WANG Yinong, YU Hong, JIN Shan Department of Oceanology and Fishery, Ningbo University, Ningbo 315211, P.R.China | 2002 | Journal of Ocean University of Qingdao2002，1，2： | 0 |
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