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| 1 | Laparoscopic total mesorectal excision of low rectal cancer with preservation of anal sphincter:A report of 82 cases显示文摘AIM: To assess the feasibility and efficacy of laparoscopic total mesorectal excision (LTME) of low rectal cancer with preservation of anal sphincter.METHODS: From June 2001 to June 2003, 82 patients with low rectal cancer underwent laparoscopic total mesorectal excision with preservation of anal sphincter. The lowest edge of tumors was below peritoneal reflection and 1.5-7 cm from the dentate line (1.5-5 cm in 48 cases, 5-7 cm in 34 cases).RESULTS: LTME with anal sphincter preservation was performed on 82 randomized patients with low rectal cancer, and 100 % sphincter preservation rate was achieved. There were 30 patients with laparoscopic low anterior resection (LLAR) at the level of the anastomosis below peritoneal reflection and 2 cm above from the dentate line; 27 patients with laparoscopic ultralow anterior resection (LULAR) at the level of anastomoses 2 cm below from the dentate line; and 25 patients with laparoscopic coloanal anastomoses (LC AA) at the level of the anastomoses at or below the dentate line. No defunctioning ileostomy was created in any case. The mean operating time was 120 minutes (ranged from 110-220 min), and the mean operative blood loss was 20 mL (ranged from 5-120 mL).Bowel function was restored and diet was resumed on day 1 or 2 after operation. The mean hospital stay was 8 days (ranged from 5-14). Postoperative analgesics were used in 45 patients. After surgery, 2 patients had urinary retention, one had anastomotic leakage, and another 2patients had local recurrence one year later. No interoperative complication was observed.CONCLUSION: LTME with preservation of anal sphincter is a feasible, safe and minimally invasive technique with less postoperative pain and rapid recovery, and importantly, it has preserved the function of the sphincter. | Zong-Guang Zhou Zhao Wang Yong-Yang Yu Ye Shu Zhong Cheng Li Li Wen-Zhang Lei Tian-Cai Wang Department of General Surgery and Institute of Digestive Surgery,West China Hospital,Sichuan University,Chengdu 610041,Sichuan Province,China | 2003 | World Journal of Gastroenterology2003，9，7： | 33 |
| 2 | Roles of Fas signaling pathway in vitamin E succinateinduced apoptosis in human gastric cancer SGC-7901 cells显示文摘AIM: To investigate the roles of Fas signaling pathway in vitamin E succinate-induced apoptosis in human gastric cancer SGC-7901 cells.METHODS: Human gastric cancer SGC-7901 cells were treated with VES at 5, 10, 20 mg@L-1, succinic acid and vitamin E as vehicle control and condition media only as untreated (UT) control. Apoptotic morphology was observed by DAPI staining. Western blot analysis was applied to measure the expression of Fas, FADD and caspase-8 proteins. After the cells were transiently transfected with Fas and FADD antisense oligonucleotides, respectively, caspase-8 activity was determined by flurometric method.RESULTS: The morphologically apoptotic changes were observed after VES treatment by DAPI staining. 23.7 % and 89.6 % apoptosis occurred after 24 h and 48 h of 20 mg@L-1 VES treatment, respectively. The protein levels of Fas, FADD and caspase-8 were evidently increased in a dose-dependent manner after 24 h of VES treatment. The blockage of Fas by transfection with Fas antisense oligonucleotides obviously inhibited the expression of FADD protein. After SGC-7901 cells were transfected with Fas and FADD antisense oligonucleotides, caspase-8 activity was obviously decreased (P<0.01), whereas Fas blocked more than FADD.CONCLUSION: VES-induced apoptosis in human gastric cancer SGC-7901 cells involves Fas signaling pathway including the interaction of Fas, FADD and caspase-8. | Kun Wu Yao Li Yan Zhao Yu-Juan Shah Wei Xia Lan Zhao,Department of Nutrition and Food Hygiene,Public Health School,Harbin Medical University,Harbin 150001,Heilongjiang Province,China Wei-Ping Yu,Genetics Institute,Texas University of USA,Austin,USA | 2002 | World Journal of Gastroenterology2002，8，6： | 30 |
| 3 | The prognostic value of preoperative serum levels of CEA,CA19-9 and CA72-4 in patients with colorectal cancer显示文摘INTRODUCTIONCarcinoembryonic antigen ( CEA) , originally described by Gold and Freedman [1] in 1965, is now an acknowledged member of immunoglobulin superfamily[2],with a role as an intracellular adhesion molecule[3].Carbohydrate antigen 19-9(CA19-9), obtained with a monoclonal antibody produced by immunizing a monoclonal antibody produced by immunizing a mouse with a colonic cancer cell line in 1979[4],is a ligand for E-selectin that plays an important role in the addhesion of cancer cells to endothelial cells [5,6]. | Chao Xu Zheng~1 Wen Hua Zhan~1 Ji Zong Zhao~2 Dong Zheng~3 Dong Ping Wang~1 Yu Long He~1 Zhang Qing Zheng~1 ~1Department of General Surgery,~2Laboratory of Surgery,~3Department of Medicine,First Affiliated Hospital,Sun Yat-Sen University of Medical Sciences,Guangzhou 510080,Guangdong Province,ChinaDr.Chao Xu Zheng now working as a surgeon and lecturer in the Department of General Surgery,First Affiliated Hospital,Sun Yat-Sen University of Medical Sciences,who is a Ph.D.student,having 7 papers published. | 2001 | World Journal of Gastroenterology2001，7，3： | 25 |
| 4 | Relationship between tumor necrosis factor-α and liver fibrosis显示文摘RelationshipbetweentumornecrosisfactorαandliverfibrosisWANGXin,CHENYueXiang,XUCaiFu,ZHAOGuoNing,HUANGYuXinandWANGQinLiD... | WANG Xin, CHEN Yue Xiang, XU Cai Fu, ZHAO Guo Ning, HUANG Yu Xin and WANG Qin Li Department of Gastroenterology, Tangdu Hospital, The Fourth Military Medical University, Xi′an 710038, Shaanxi Province, China | 1998 | World Journal of Gastroenterology1998，4，1： | 21 |
| 5 | Meteorological control on CO_2 flux above broad-leaved Korean pine mixed forest in Changbai Mountains显示文摘The impacts of temperature, photosynthetic active radiation (PAR) and vapor pressure deficit (VPD) on CO2 flux above broad-leaved Korean pine mixed forest in the Changbai Mountains were studied based on eddy covariance and meteorological factors measurements.The results showed that, daytime CO2 flux was mainly controlled by PAR and they fit Michaelis-Menten equation. Meanwhile VPD also had an influence on the daytime flux. Drier air reduced the CO2 assimilation of the ecosystem, the drier the air, the more the reduction of the assimilation. And the forest was more sensitive to VPD in June than that in July and August. The respiration of the ecosystem was mainly controlled by soil temperature and they fit exponential equation. It was found that this relationship was also correlated with seasons; respiration from April to July was higher than that from August to November under the same temperature. Daily net carbon exchange of the ecosystem and the daily mean air temperature fit exponential equation. It was also found that seasonal trend of net carbon exchange was the result of comprehensive impacts of temperature and PAR and so on. These resulted in the biggest CO2 uptake in June and those in July and August were next. Annual carbon uptake of the forest ecosystem in 2003 was -184 gC. m-2. | GUAN Dexin, WU Jiabing, YU Guirui, SUN Xiaomin, ZHAO Xiaosong, HAN Shijie & JIN Changjie Institute of Applied Ecology, Chinese Academy of Sciences, Shenyang 110016, China Institute of Geographic Sciences and Natural Resources Research, Chinese Academy of Sciences, Beijing 100101, China | 2005 | Science China Earth Sciences2005，48，z1： | 15 |
| 6 | Establishment of a novel corneal endothelial cell line from domestic rabbit,Oryctolagus curiculus显示文摘To develop a rabbit corneal endothelial (RCE) cell line, in vitro culture of RCE cells was initiated from Oryctolagus curiculus corneas and a novel RCE cell line was established in this study. To initiate the primary culture of RCE cells, corneas from rabbit eyes were sliced and attached into glutin-coated wells with endothelial cell surface down. After being cultured at a time-gradient interval from 48 to 6 h, the corneal slices were detached and reattached into new wells, respectively. Cells in the wells containing only a pure population of RCE cells were collected and cultured in 20% FBS-DMEM/F12 medium con- taining chondroitin sulfate, ocular extract, epidermal growth factor (EGF), basic fibroblast growth factor (bFGF), carboxymethyl-chitosan, N-acetylglucosamine hydrochloride, glucosamine hydrochloride, culture medium of rabbit corneal stromal cells and oxidation-degradation products of chondroitin sul- fate at 37℃, 5% CO2. The cultured RCE cells, in quadrangle and polygonal shapes, proliferated to con- fluence 3 weeks later. During the subsequent subculture, the shape of RCE cells changed gradually from polygonal to more fibroblastic. A novel RCE cell line, growing at a steady rate, with a population doubling time of 53.8 h, has been established and subcultured to passage 67. Chromosome analysis showed that the RCE cells exhibited chromosomal aneuploidy with the modal chromosome number of 44. The results of immuno-cytochemical staining with neuron specific enolase (NSE) confirmed that the RCE cells were in neuroectodermal origin. Combined with the results of vascular endothelial growth factor (VEGF) treatment and endothelial cell morphology recovery, it can be concluded that the cell line established here is an RCE cell line. This RCE cell line may serve as a useful tool in theoretical re- searches of mammalian corneal endothelial cells, and may also have potential application in artificial corneal endothelium development. | FAN TingJun, ZHAO Jun, FU YongFeng, CONG RiShan, GUO RuiChao, LIU WanShun, HAN BaoQin, YU QiuTao & WANG JingCollege of Marine Life Sciences, Division of Life Science and Technology, Ocean University of China, Qingdao 266003, China | 2007 | Science China(Life Sciences)2007，50，2： | 15 |
| 7 | The study of neighboring nucleotide composition and transition/transversion bias显示文摘Base substitution is one of the raw fuels that produce genetic variation and drive evolu-tion. Recent studies have shown that the genome components affect mutation patterns to some extent. In order to infer the correlation between the Transition/Transversion ratio (Ts/Tv) and the number of immediately adjacent A&T nucleotides, we investigated 3611007 Oryza sativa SNPs (including 45462 coding SNPs, and 242811 intronic SNPs) and 32019 Arabidopsis SNPs. The results show that Ts/Tv is negatively correlated with the number of immediately adjacent A&T in O. sativa and Arabidopsis. We further calculated AT2 (the number of SNPs whose immediately adjacent nucleotides are either A or T) and AT0 (the number of SNPs whose immediately adjacent nucleotides are either C or G) for all 6 types of SNPs. C/G SNP of O. sativa and Arabidopsis has the highest AT2/AT0, which denotes C/G SNP may be influenced by the adjacent A&T nucleotides mostly. For SNPs in O. sativa, the neighboring effect of A&T nucleotides is limited to 2 nucleotides on both sides; for SNPs in Arabidop-sis, the effect extends no more than 4 nucleotides on both sides. | ZHAO Hui1,3*, LI Qizhai1,2,3*, LI Jun1, ZENG Changqing1, HU Songnian1 & YU Jun1 1. Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100030, China 2. Academy of Mathematics and Systems Science, Chinese Academy of Sciences, Beijing 100080, China 3. Graduate University of Chinese Academy of Sciences, Beijing 100039, China | 2006 | Science China(Life Sciences)2006，49，4： | 12 |
| 8 | Grain Size and Wettability of TiO_2/SiO_2 Photocatalytic Composite Thin Filing显示文摘The uniform transparent TiO2/SiO2 photocatalytic composite thin films are prepared by sol-gel method on the soda lime glass substrates, and characterized by UV-visible spectroscopy, X-ray diffraction (XRD), transmission electron microscopy (TEM), BET surface area, FTIR spectroscopy and X-ray photoelectron spectroscopy (XPS). It was found that the addition of SiO2 to TiO2 thin films can suppress the grain growth of TiO2 crystal, increase the hydroxyl content on the surface of TiO2 films, lower the contact angle for water on TiO2 films and enhance the hydrophilic property of TiO2 films. The super-hydrophilic TiO2/SiO2 photocatalytic composite thin films with the contact angle of 0° are obtained by the addition of 10%-20% SiO2 in mole fraction. | Jiaguo Yu, Xiujian Zhao, Jimmy C Yu, Jun Lin (State Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Wuhan University of Technology, Wuhan 430070, China Deportment of Chemised The Chinese University of Hong Kong, Hong Kong, | 2001 | Rare Metals2001，20，2： | 11 |
| 9 | Aoyitake plagiogranite in western Tarim Block, NW China: Age, geochemistry, petrogenesis and its tectonic implications显示文摘SHRIMPP U-Pb zircon age and geochemical and Nd isotopic data are reported for the Aoyitake plagiogranite in western Tarim Block, NW China. The plagiogranite intruded the Middle Pro- terozoic and Lower Carboniferous with an exposure area of ca. 60 km2 and crystallized at 330.7±4.8 Ma. Rock types mainly include tonalite, trondhjemite and minor amounts of diorite and quartz-diorite. Feldspars in the rocks are dominated by oligoclase-andesine, and minor perthite observed locally. The granites are sodic with Na/K ratios (molar) between 4 and 87. Total REE (50-220 ppm) show a clear positive correlation with SiO2. There is no LRRE/HREE fractionation (LaN/YbN=0.5-1.5), me- dium negative Eu anomalies (δ Eu=0.3-0.6), high Y content and low Sr/Y ratio (~1.0). These granites exhibit relatively juvenile Nd T2DM model ages of 470 to 580 Ma and positive εNd(331 Ma) values of 6.23 to 7.65. The aforementioned characteristics are similar to those of ocean island or ocean ridge plagiogranites. However, the regional geology, especially its scale, precludes that the plagiogranite pluton was derived directly from fractionational crystallization of mantle-derived basaltic magma. We interpreted that the primary magma of the pluton might be tonalitic in composition generated by ca. 50% partial melting of the juvenile basaltic crust. The primary magma experienced intensive frac- tionational crystallization, and intruded into the middle to upper crusts to form the granite pluton. In combination with the previous regional geological data, it is concluded that the plagiogranite pluton was emplaced within the Tarim Block in respond to the Carboniferous continental rifting along the Tianshan orogenic belt. | ZHANG Chuanlin1,2, YU Haifeng3, YE Haimin2, ZHAO Yu2 & ZHANG Dongsheng4 1. Key Laboratory of Isotope Geochronology and Geochemistry, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou 510640, China 2. Nanjing Institute of Geology and Mineral Resources, Nanjing 210016, China 3. Tianjin Institute of Geology and Mineral Resources, Tianjin 300170, China 4. The 2nd Regional Geological Investigation Party, Xinjiang Bureau of Geology and Mineral Resources, Changji 831100, China | 2006 | Science China Earth Sciences2006，49，11： | 11 |
| 10 | The high-resolution climate recorded in the δ^(18)O of Porites lutea from the Nansha Islands of China显示文摘A Porites lutea core from Yongshu Reef of Nansha Islands covering 50 years growth history was ana-ly/ed for oxygen isotopic composition with monthly and seasonally resolution. The calibration of the δ18O with the instrumental temperature indicated that the coral δ18O is a good indicator for sea surface temperature (SST) and air temperature (t). It can be used to reconstruct the SST and air temperature of the Yongshu Reef sea area. In addition, the coral δ18O provides signatures for the intensity of the East Asia monsoon and it is a record for the activities of El Nino events. With the calibrated SST and air temperature formulas, the most recent fifty years SST and air temperature were reconstructed based on the coral δ18O, thus back up the understanding of the climate of Nansha Islands to 1950. far beyond the limit of the instrumental recording since September 1988. It was found that, in general, increasing 1℃ air temperature results in 0.24‰decrease in skeletal δ18O. | YU Kefu, CHEN Tegu, HUANG Dingcheng, ZHAO Huanting, ZHONG Jinliang & LIU Dongsheng (LIU Tungsheng)South China Sea Institute of Oceanoiogy, Chinese Academy of Sciences. Guangzhou 510301, China:Geology and Geophysics Institute. Chinese Academy of Sciences, Beijing 100029, China | 2001 | Chinese Science Bulletin2001，46，24： | 10 |
| 11 | Study on DNA Cytosine Methylation of Cotton (Gossypium hirsutum L.) Genome and Its Implication for Salt Tolerance显示文摘To study the relations between DNA methylation and abiotic stress responses in cotton (Gossypium hirsutum L.),the methylation-sensitive amplified polymorphism (MSAP) method was used to investigate the differences in methylation level and the change of cytosine methylation patterns under salt (NaCl) stress in two different salt-tolerant cotton lines.The results showed that the number of the cytosine methylation of CCGG sites in high salt-tolerant cotton line was less than that in low salt-tolerant line.Under salt stress,extensive cytosine methylation alterations including hypermethylation and demethylation as well as the potential conversion of methylation types occurred in the salt-treated cotton line compared with the corresponding control.Interestingly,salt stress-induced demethylation loci that occurred in high salt- tolerant cotton line were greater than those in low salt-tolerant cotton line,however,salt stress-induced hypermethylation loci in the high salt-tolerant cotton line were less than those in low salttolerant cotton line.It suggested that the demethylation positively contributed to salt tolerance and the hypermethylation had negative effect on salt tolerance in cotton. | ZHAO Yun-lei,YU Shu-xun,YE Wu-wei,WANG Hong-mei,WANG Jun-juan and FANG Bao-xing Cotton Research Institute,Chinese Academy of Agricultural Sciences (CAAS)/Key Laboratory of Cotton Genetic Improvement,Ministry of Agriculture,Anyang 455000,P.R.China | 2010 | Agricultural Sciences in China2010，9，6： | 10 |
| 12 | A NUMERICAL STUDY ON THE PATH AND ORIGIN OF THE YELLOW SEA WARM CURRENT (YSWC)显示文摘A three dimensional baroclinic model (POM) is employed to study the path, orgin and strength of the Yellow Sea Warm Current (YSWC). The model produced results are compared with the observed temperature and salinity fields, the trajectories of drifters and moored current meter data. The results show: (1) It is indicated for the first time that the YSWC in winter orignates from the middle sector (28°N, 126°E), the truning directional sector (30°N, 127°E) of the Kuroshio in the East China Sea (ECS) and the separated sector of the Tsushima Warm Current (TsWC) at (31°N, 128°E), while in summer mainly originates from the Taiwan Warm Current (TaWC) and partly from the separated sector of the TsWC. This path is consistent with the main distribution feature of the quasi synoptic observed temperature and salinity. The model produced anticyclonic gyre (28°N, 125.5°E) branched from the middle sector of the ECS Kuroshio agrees with the observed results of the satellite drifters. (2) The model produced YSWC is located between 50~60m isobath on the West Side of the Yellow Sea Trough (YST), which is consistent with the location of the Warm and Saline tongue. The model produced cyclonic gyre centering at (36°N, 124.5°E) coincides with the observed results in Feb. 1997. The traditional view indicates that the Northern Jiangsu Coastal Current (NJCC) turns eastward at (32.5°N, 122°E). However, we think that the NJCC goes southward and only the coastal water invades near (32.5°N, 122°E). The model produced path is consistent with the warm tongue in the range of 34° 35°N, 122.5° 123.5°E in 30m layer. (3) The model produced YSWC is strong in winter and weak in summer, which coincides with the observations. The northward volume transport along 35°N section in winter and summer are 0.72sv and 0.38sv, respectively, with an annual flux of about 1.54·10 13 m 3. The volume transport entering the Bohai Sea in winter and summer are 0.19sv and 0.09sv, respectively, with an annual flux of about 4.37·10 12 m 3. | Qiao Fang li, Xu Xiao biao, Tang Yu xiang, Zhao Wei Labortary of Marine Science and Numerical Modeling, State Oceanic Administration, Qingdao 266061, China | 2001 | Journal of Hydrodynamics2001，13，3： | 9 |
| 13 | Differential Gene Expression Between Hybrids and Their Parents During the Four Crucial Stages of Cotton Growth and Development显示文摘The study aims to clarify the differential gene expression between cotton hybrids and their parents in order to better understand the molecular basis of cotton heterosis. The research focused on cotton heterotic and lower heterotic hybrids and their parents during the four crucial stages, which were analyzed using a differential display technique. The results indicated that there were both quantitative and qualitative differences in gene expression amongst them. The quantitative differences include over- and under-expression of parental genes and the dominant expression of highly-expressed parental genes in hybrids. In contrast, the qualitative differences are the following: (i) Bands were observed in both parents but not in the F1 hybrid (BPnF1); (ii) bands occurred in either of the parents but not in the F1 hybrid (UPnF1); (iii) bands presented only in the F1 hybrid but not in either of the parents (UF1nP); and (iv) bands were detected in either of the parents and the F1 hybrid (UPF1). Overall, the major differences of gene expression occurred in the qualitative level and four related differential patterns were observed. Furthermore, the amount of differential patterns during the flowering stage was relatively higher than those of other stages. At this juncture, both the amount of hybrid-specific expression patterns at flowering stage and the silenced expression patterns at boll-forming stage in highly heterotic hybrids were found higher than those in the lower heterotic ones. It was concluded that significant differences of gene expression in leaves were present between cotton hybrid and its parents during the whole growing stages. Hence, these differences might be responsible for the observed cotton heterosis. | ZHAO Yun-lei, YU Shu-xun, XING Chao-zhu, FAN Shu-li, SONG Mei-zhen and YE Wu-wei Cotton Research Institute, Chinese Academy of Agricultural Sciences(CAAS)/Key Laboratory of Cotton Genetic Improvement, Ministry of Agriculture, Anyang 455000, P.R.China | 2009 | Agricultural Sciences in China2009，8，2： | 8 |
| 14 | Determination of interface width value in phase-field simulation of dendritic growth into undercooled melt显示文摘The influence of the interface width value on the simulation results and its dependence upon thermo-physical parameters in the phase-field simulation of dendritic growth into undercooled melt are investigated. After choosing the reasonable interface width value, the tip velocities of dendritic growth in Ni melt under different undercoolings are calculated and compared with the experimental data in order to benchmark our results. It is shown that the reasonable interface width value, which is determined by the undercooling, anisotropy, interface kinetic, and thermal diffusivity, has to be taken low enough, and the agreement of our results with experimental data verifies that the credible results can be achieved as long as the interface width value is adequately low. This paper provides the basis of determining interface width value in simulating dendritic growth into undercooled melt by phase-field approach. | YU Yanmei, YANG Gencang , ZHAO Dawen and LU Yili(State Key Laboratory of Solidification Processing, Northwestern Polytechnical University, Xi’an 710072, China) | 2002 | Progress in Natural Science:Materials International2002，12，3： | 8 |
| 15 | Malnutrition and Quality of Life in Chinese Cancer Patients: a Clinical Study of 23,994 Subjects显示文摘Background Malnutrition is common in patients with cancer,and can negatively impact their quality of life(QoL)and even survival.However,there is currently no large data available on the prevalence of malnutrition in Chinese cancer patients.This study evaluated the prevalence of malnutrition and the QoL of Chinese patients with locoregional,recurrent or metastatic cancer.Methods We conducted a nationwide observational,multi-center,hospital-based cross-sectional study within the Chinese Society of Nutritional Oncology(CSNO)Network.All of the patients were diagnosed with one of the following 18 different types of malignant tumors:lung cancer,gastric cancer,liver cancer,colorectal cancer,breast cancer,esophageal cancer,cervical cancer,endometrial cancer,nasopharyngeal carcinoma,malignant lymphoma,leukemia,pancreatic cancer,ovarian cancer,prostate cancer,bladder cancer,brain cancer,biliary tract malignant tumors or gastrointestinal stromal tumors.These patients were enrolled from 72 hospitals located in different regions of China.The patients’nutritional status was evaluated based on the body mass index(BMI),loss of bodyweight,laboratory measurements and patient generated-subjective global assessment(PG-SGA)scores.The cancer patients’physical status and QoL were assessed by the Karnofsky Performance Status(KPS)questionnaire and the European Organization for Research and Treatment of Cancer(EORTC)QLQ-C30 questionnaire,respectively.Results From December 2013 to April 2016,23,994 patients hospitalized for cancer treatment(such as surgery,chemotherapy or radiotherapy)were enrolled in the study.The patients included 12,494(52.9%)males and 11,124(47.1%)females.The mean age was 55.8±13.7 years.The proportions of patients in cancer stagesⅠ,Ⅱ,Ⅲ,Ⅳand uncertain were 11.5%,20.3%,27.5%,30.2%and 10.5%,respectively.Among the 23,994 inpatients,the proportions of patients who were underweight(BMI<18.5 kg/m2),normal(18.5 kg/m2 | Hong Xia Xu Chun Hua Song Zhen Ming Fu Chang Wang Zeng Qing Guo Yuan Lin Ying Ying Shi Wen Hu Yi Ba Su Yi Li Zeng Ning Li Kun Hua Wang Jing Wu Ying He Jia Jun Yang Cong Hua Xie Fu Xiang Zhou Xin Xia Song Gong Yan Chen Wen Jun Ma Su Xia Luo Zi Hua Chen Ming Hua Cong Hu Ma Chun Ling Zhou Wei Wang Qi Luo Yong Mei Shi Yu Mei Qi Hai Ping Jiang Wen Xian Guan Jun Qiang Chen Jia Xin Chen Yu Fang Lan Zhou Yong Dong Feng Rong Shao Tan Tao Li Jun Wen Ou Qing Chuan Zhao Jian Xiong Wu Min Weng Qing Hua Yao Jiu Wei Cui Wei Li Han Ping Shi the Investigation on Nutrition Status and Clinical Outcome of Common Cancers(INSCOC)Group | 2021 | Journal of Nutritional Oncology2021，6，1： | 8 |
| 16 | Eddy flux corrections for CO_2 exchange in broad-leaved Korean pine mixed forest of Changbai Mountains显示文摘Based on analysis of mechanisms causing energy no-closure and nocturnal low fluxes issues for CO2 exchange studies by eddy covariance method, corrections were done with the raw data sets obtained from Changbai Mountains forest flux site, to evaluate the impacts of sonic anemometer tilt, frequency response limitations and advection on estimation of CO2 exchange, respectively. The results show that the planar fit coordinate transforming method is superior to the streamline coordinate transforming method in tilt correction. The latter could cause a systematical underestimation of eddy fluxes relating with the angle of sensor and terrain tilt. The underestimation of CO2 and energy fluxes for frequency response limitations average 3.0% and 2.0% during daytime, respectively, which increase by 9.0% and 5.5% during nighttime, respectively. The corrections of frequency response limitations are closely related to atmospheric stability. The advection loss of CO2 fluxes is dominated by nocturnal vertical advection, which is at least 18% when the horizontal advection is neglected. It is suggested that more work be done to understand the characteristics of horizontal advection and turbulent eddies under a complexcircumstance. | WU Jiabing, GUAN Dexin, SUN Xiaomin, YU Guirui, ZHAO Xiaosong, HAN Shijie & JIN Changjie Institute of Applied Ecology, Chinese Academy of Sciences, Shenyang 110016, China Graduate school of the Chinese Academy of Sciences, Beijing 100093, China Institute of Geographic Sciences and Natural Resources Research, Chinese Academy of Sciences, Beijing 100101, China | 2005 | Science China Earth Sciences2005，48，z1： | 8 |
| 17 | Comparative studies on epithelial lesions at gastric cardia and pyloric antrum in subjects from a high incidence area for esophageal cancer in Henan,China显示文摘ComparativestudiesonepitheliallesionsatgastriccardiaandpyloricantruminsubjectsfromahighincidenceareaforesophagealcancerinHena... | GAO ShanShan1, ZHOU Qi1, LI YongXin1, BAI YongMin1, ZHENG ZuoYu1, ZOU JianXiang1, LIU Gang1, FAN ZongMin1, QI YiJun1, ZHAO Xin1 and WANG LiDong1,2Keywords esophageal neoplasms stomach neoplasms gastric ca | 1998 | World Journal of Gastroenterology1998，4，4： | 8 |
| 18 | The effects of vitamin E succinate on the expression of c-jun gene and protein in human gastric cancer SGC-7901 cells显示文摘AIM:Toinvestigate the effects of vitamin E succinate(VES)on the expression of c-jun gene and protein in human gastric cancer SGC-7901 cells.METHODS:After SGC-7901cells were treated with VESat different doses(5,10,20mg·L^-1)at different time,reverse transcription-PCR technique was used to detect the level of c-jun mRNA;Western Blot was applied to measure the expression of c-jun protein.RESULTS:After the cells were theated with VESat 20mg·L^-1for 3h,the expression rapidly reached its maximun that was3.5times of UT control(P<0.01).The level of c-jun mRNA was also increased following treatment of VESfor 6h.However the expression after treatment of VES at 5mg·L^-1for24h was 1.6tmes compared with UTcontrol(P<0.01),Western blot analysis showed that the level of c-jun protein was obviusly elevated in VES-treated SGC-7901cells at 20mg·L^-1for3h,The expression of c-jun protein was gradually increased after treatment of VES at 20mg·L^-1for3,6,12and24h,respectively,with an evident time-effect relationship.CONCONCLUSION:The levels of c-jun mRNA and protein in VES-treated SGC-7901cells were increased in a dose-and time-dependent manner;the expression of c-jun was prolonged by VES,indicating that c-jun is involvedin VES-induced apoptosis in SGC-7901 cells. | Yah Zhao Kun Wu Wei Xia Yu-Juan Shan Li-Jie Wu Department of Nutrition and Food Hygiene,Public Health School,Harbin Medical University,Harbin 150001,Heilongjiang Province,China Wei-Ping Yu Genetics Institute,Texas University of USA,Austin,USA | 2002 | World Journal of Gastroenterology2002，8，5： | 8 |
| 19 | Atmospheric correction of HJ-1A/B CCD images over Chinese coastal waters using MODIS-Terra aerosol data显示文摘This paper demonstrates an atmospheric correction method to process HJ-1A/B CCD images over Chinese coastal waters with the aid of MODIS-Terra aerosol information.Based on the assumption of zero water-leaving radiance at the two near-infrared (NIR)bands or the shortwave infrared(SWIR)bands,the atmospheric aerosol optical depth(AOD)is firstly retrieved from MODIS-Terra with a simple extension of the NIR-SWIR combined atmospheric correction approach embedded in SeaDAS (SeaWiFS data analysis system).Then the'turbid'and'non-turbid'waters are separated by the turbid water index.Maximum probability of AOD at 551 nm band is derived based on the NIR information over'non-turbid'waters and FLAASH model is selected to do the atmospheric correction of the HJ-1A/B CCD imagery using the AOD values of highest probabilities as input.Similarly,according to the histogram of the AOD distribution at 551 nm band,the studied turbid water area is divided into several blocks and HJ-1A/B CCD imagery is corrected with the corresponding AOD values displayed with the highest frequency in each block.This method has been applied to several HJ-1A/B images over Chinese coastal waters and validated by synchronous in-situ data.The results have shown that this method is effective in the atmospheric correction process of HJ-1A/B CCD images for ocean color remote sensing study and application in the coastal waters. | TIAN LiQiao 1,LU JianZhong 1,CHEN XiaoLing 1,2,3,YU ZhiFeng 1,XIAO JingJing 1,QIU Feng 1 & ZHAO Xi 1 1 State Key Laboratory of Information Engineering in Surveying,Mapping and Remote Sensing,Wuhan University,Wuhan 430079,China 2Key Laboratory of Poyang Lake Wetland and Watershed Research,Ministry of Education,Jiangxi Normal University,Nanchang 330022,China 3 The Key Laboratory of Poyang Lake Environment and Resource Utilization,Ministry of Education,Nanchang University,Nanchang 330031,China | 2010 | Science China(Technological Sciences)2010，53，S1： | 8 |
| 20 | The gravitational gradient tensor’s invariants and the related boundary conditions显示文摘Here we report new approaches of recovering the Earth gravitational field from GOCE (Gravity field and steady-state Ocean Circulation Explorer) gradiometric data with the help of the gradient tensor’s invariants. Our results only depend on GOCE satellite’s position and gradiometry, in other words, they are completely independent of the satellite attitude. First, starting from the invariants, linearization models are established, which can be referred as the general boundary conditions on the satellite’s orbit. Then, the spherical approximation expressions for the models are derived, and the corresponding solving methods for them are discussed. Furthermore, considering effects of J2-term, the spherical approximation models are improved so that the accuracies of the boundary conditions can be theoretically raised to O ( J 2/2 T), which is approximately equivalent to O(T2). Finally, some arithmetic examples are constructed from EGM96 model based on the derived theories, and the computational results illustrate that the spherical models have accuracies of 10-7 and the order recovering the gravitational field can reach up to 200, and the models with regard to effect of J2-term have accuracies of 10-8 and the order can reach up to 280. | YU JinHai1,2,3 & ZHAO DongMing4 1 College of Earth Science, Graduate University of Chinese Academy of Sciences, Beijing 100049, China 2 Institute of Geodesy and Geophysics, Chinese Academy of Sciences, Wuhan 430077, China 3 State Key Laboratory of Astronautic Dynamics, Xi’an 710043, China 4 Zhengzhou Institute of Surveying and Mapping, Zhengzhou 450052, China | 2010 | Science China Earth Sciences2010，53，5： | 7 |
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