|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。 | Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉 叶鹏 | 2017 | 中华高血压杂志2017，25，9： | 2 |
| 2 | Making a tooth: growth factorsξ┐ transcription factorsξ┐ and stem cells显示文摘 | Zhang YD Chen Z Song YQ Liu C Chen YR | 2006 | 中国生物学文摘2006，20，5： | 2 |
| 3 | Epidemiology of community-acquired Pneumoniae respiratory tract infections among hospitalized dren,incfuding relationships with meteorological factors显示文摘 | Chen Zg Y Mycoplasma Chinese ch Hippokratis an YD Wang YQ et aI | 2015 | 17(1):20-262015，17，1： | 1 |
| 4 | Stress-induced corticotropin-releasing hormone-mediated NLRP6 Inflammasome Inhibition and Transmissible Enteritis in mice显示文摘 | Sun YD Zhang M Chen CC | 2013 | Gastroenterology2013，144，7： | 1 |
| 5 | Artificial neural networks analysis of surface-enhanced laser desorption/ionization mass spectra of serum protein pattern distinguishes colorectal cancer from healthy population显示文摘 | Chen YD Zheng S Yu JK | 2004 | Clin Cancer Res2004，10，24： | 1 |
| 6 | Serum N-terminal probrain natriuretic peptide level is a significant prognostic factor in patients with severe sepsis among Southwest Chinese population显示文摘 | Zhang XH Dong Y Chen YD | 2013 | Eur Rev Med Pharmacol Sci2013，17，4： | 1 |
| 7 | Effect of metform in onpostprandial Lipemia in patients with fairly to poorly controlled NIDDM显示文摘 | Jeppesen J Zhou My Chen YD | 1994 | Diabetes Care1994，17，10： | 1 |
| 8 | Comparison of three treat- ment approaches to decreasing cardiovascular disease risk in nondiabetie insulin-resistant dyslipidemic subjects 显示文摘 | Abbasi F Chen YD Farin HM | 2008 | Am J Cardiol2008，102，1： | 1 |
| 9 | Dexamethasone,ondansetron,and their combination and postoperative nausea and vomiting in children undergoing strabismus surgery:A meta-analysis of randomized controlled trials显示文摘 | Shen YD Chen CY Wu CH | 2014 | Paediatr Anaesth2014，24，5： | 1 |
| 10 | Entrapment of posterior interosseous nerve of forear:report of 25 cases显示文摘 | Gu YD Zhang GM | 1994 | Chin Med J Engl1994，107，3： | 1 |
| 11 | Myocardial bridging in Taiwan:depiction by multi-detector computed tomography coronary angiography显示文摘 | Chen YD Wu MH Sheu MH | 2009 | J Formos Med Assoc2009，108，6： | 1 |
| 12 | Determination of sweroside in rat plasma and bile for oral bioavailability and hepatobiliary ex-cretion显示文摘 | LUO YD CHEN J CAO J | 2009 | Chem Pharm Bull(Tokyo)2009，57，1： | 1 |
| 13 | Insulin resistance and hyperinsulinemiain individuals with small,dense low density lipoprotein particles显示文摘 | Reaven GM Chen YD Jeppesen J | 1993 | J C1in lnvest1993，92，： | 1 |
| 14 | The G -protein -coupled bile acid receptor, Gpbarl (TGR5), negatively regulates hepatic inflammatory response through antagonizing nuclear factor kap- pa light-chain enhance of activated B cells(NF -kappa B)in mice显示文摘 | WANG YD CHEN WD YU D | 2011 | Hepatoloqv2011，54，4： | 1 |
| 15 | Recent situation research of anti-oncogene PTEN and intestine tumor 显示文摘 | ZHANG YD CHEN H ZHANG CY | 2002 | China Journal of Modem Medicine2002，12，22： | 1 |
| 16 | Reversal of aberrant splicing of beta-thalassaemia allele ( IVS-2-654 C- > T) by antisense RNA expression vector in cultured human erythroid cells 显示文摘 | Gong L C u XF Chen YD | 2000 | Br J Haematol2000，111，1： | 1 |
| 17 | Clonorchiasis sinensis in china 显示文摘 | Xu LQ Yu SH chen YD | 2005 | Asian parasito logy series mong raph2005，1，： | 1 |
| 18 | Concurrent hypercalcemia nursing显示文摘 | Wang H Chen YD Zheng M | 2013 | Journal of clinical rational drug use of bone metasta sis of breast cancer2013，6，33： | 1 |
| 19 | Long-term outcomes of adjuvant radiotherapy after surgical resection of central neurocytoma 显示文摘 | CHEN YD LI WB FENG J | 2014 | Radiation Oneology2014，242，9： | 1 |
| 20 | Valproate pretreatment protects dopaminergic neurons from LPS-induced neurotoxicity in rat primary midbrain cultures: role of microglia显示文摘 | Peng GS Li G Tzeng NS Chen PS Chuang DM Hsu YD Yang S Hong JS | 2006 | 中国生物学文摘2006，20，10： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员