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| 1 | Prevalence of clonorchiasis in patients with gastrointestinal disease: A Korean nationwide multicenter survey显示文摘AIM: To investigate prevalence of Clonorchis sinensis in patients with gastrointestinal symptoms, and the relation of the infection to hepatobiliary diseases in 26 hospitals in Korea.METHODS: Consecutive patients who had been admitted to the Division of Gastroenterology with gastrointestinal symptoms were enrolled from March to April 2005. Of those who had been diagnosed with clonorchiasis, epidemiology and correlation between infection and hepatobiliary diseases were surveyed by questionnaire.RESULTS: Of 3080 patients with gastrointestinal diseases, 396 (12.9%) had clonorchiasis and 1140 patients (37.2%) had a history of eating raw freshwater fish. Of those with a history of raw freshwater fish ingestion, 238 (20.9%) patients had clonorchiasis. Cholangiocarcinoma was more prevalent in C. sinensis-infected patients than non-infected patients [34/396 (8.6%) vs 145/2684 (5.4%), P = 0.015]. Cholangiocarcinoma and clonorchiasis showed statistically significant positive cross-relation (P = 0.008). Choledocholithiasis, cholecystolithiasis, cholangitis, hepatocellular carcinoma, and biliary pancreatitis did not correlate with clonorchiasis.CONCLUSION: Infection rate of clonorchiasis was still high in patients with gastrointestinal diseases in Korea, and has not decreased very much during the last two decades. Cholangiocarcinoma was related to clonorchiasis, which suggested an etiological role for the parasite. | Ho Gak Kim Jimin Han Myung-Hwan Kim Kyu Hyun Cho Im Hee Shin Gwang Ha Kim Jae Seon Kim Jin Bong Kim Tae Nyeun Kim Tae Hyeon Kim Tae Hyo Kim Jae Woo Kim Ji Kon Ryu Young-Soo Moon Jong Ho Moon Sung Jae Park Chan Guk Park Sung-Jo Bang Chang Heon Yang Kyo-Sang Yoo Byung Moo Yoo Kyu Taek Lee Dong Ki Lee Byung Seok Lee Sang Soo Lee Seung Ok Lee Woo Jin Lee Chang Min Cho Young-Eun Joo Gab Jin Cheon Young Woo Choi Jae Bok Chung Yong Bum Yoon | 2009 | World Journal of Gastroenterology2009，15，1： | 15 |
| 2 | Colonoscopy-induced ischemic colitis in patients without risk factors显示文摘Ischemic colitis is the most common form of intestinal ischemia.It is a condition that is commonly seen in the elderly and among individuals with risk factors for ischemia.Common predisposing conditions for ischemic colitis are major vascular occlusion,small vessel disorder,shock,some medications,colonic obstructions and hematologic disorders.Ischemic colitis following colonoscopy is rare.Here,we report two cases of ischemic colitis after a routine screening colonoscopy in patients without risk factors for ischemia. | Sang Ok Lee Sae Hee Kim Sung Hee Jung Chan Woong Park Min Ji Lee Jin A Lee Hyun Cheol Koo Anna Kim Hyun-Young Han Dong-Wook Kang | 2014 | World Journal of Gastroenterology2014，20，13： | 9 |
| 3 | 3-Dimensional liver volume assessment in patients with hepatitis B virus-related liver cirrhosis during long-term oral nucleos(t)ide analogues therapy显示文摘AIM To assess the effect of long-term oral nucleos(t)ide analogues(NUCs) therapy on liver volume change in patients with suppress hepatitis B virus(HBV)-related liver cirrhosis.METHODS We reviewed the data of na?ve patients with HBVrelated liver cirrhosis, who had taken oral NUCs therapy, between 2003 and 2007 at Chonbuk University Hospital. We analyzed two consecutive sets of abdominal computerized tomography scans-one at the time oftreatment initiation and another at the second-year follow-up. Liver volume was calculated by 3-dimensional liver extraction volumetry program.RESULTS A total of 55 patients(34 males) were included. There was 114.3 m L ± 167.8 m L(12.9% ± 17.9%) of increase in liver volume during the two years of NUCs therapy(993.8 m L ± 242.8 m L at baseline vs 1108.1 m L ± 263.3 m L at two-year follow-up, P < 0.001). The ratio of the measured baseline liver volume to the estimated standard liver volume was improved from 70.8% to 78.0%. An increase in liver volume was shown not only in patients with compensated cirrhosis(P = 0.046) but also in those with decompensated cirrhosis(P < 0.001). Significant factors for volume increases were Child-Turcotte-Pugh grade and model for end-stage liver disease score improvement without virological breakthrough. In multiple linear regression analysis, delta albumin and delta alanine aminotransferase levels showed a significant association with the increase in liver volume(P = 0.002 and 0.005, respectively).CONCLUSION Long-term oral NUCs therapy in patients with HBVrelated liver cirrhosis lead to significant increase in liver volume assessed with 3-dimensional liver extraction volumetry program. | Chang Hun Lee In Hee Kim Jin Chang Moon Seung Young Seo Seong Hun Kim Sang Wook Kim Seung Ok Lee Soo Teik Lee Dae Ghon Kim Jae Do Yang Hee Chul Yu | 2017 | World Journal of Gastroenterology2017，23，2： | 6 |
| 4 | Diaphragm disease compared with cryptogenic multifocal ulcerous stenosing enteritis显示文摘As the use of drugs such as nonsteroidal anti-inflammatory drugs (NSAIDs) increases,so too do gastrointestinal ulcers,bleeding,perforation and obstruction.Diaphragm disease of the small intestine is formed by submucosal fibrosis and destruction of lamina muscularis due to chronic ulceration,which corresponds to the most severe stage of NSAID enteropathy.It may lead to stricture of the small intestine.If such ulcerations and strictures in the small intestine are multiple,differential diagnosis is between diaphragm disease and cryptogenic multifocal ulcerous stenosing enteritis (CMUSE),because the gross findings of diaphragm disease are similar to those of CMUSE.We report a rare case of diaphragm disease caused by NSAID.It has been finally confirmed by capsule endoscopy and the origin of chronic obscure gastrointestinal bleeding was found to be multiple ulcers and strictures in the small intestine.After operation,we diagnosed the patient with diaphragm disease rather than CMUSE. | Sook Hee Chung Yunju Jo Sang Ryol Ryu Sang Bong Ahn Byoung Kwan Son Seong Hwan Kim Young Sook Park Young Ok Hong | 2011 | World Journal of Gastroenterology2011，17，23： | 5 |
| 5 | Nonalcoholic fatty liver disease is associated with coronary artery disease in Koreans显示文摘AIM:To investigate whether nonalcoholic fatty liver disease(NAFLD)affects coronary artery disease(CAD)and identify candidate mediators.METHODS:Patients who underwent coronary angiography were consecutively recruited.The patients were classified into four groups by coronary artery stenosis:A,insignificant;B,one-vessel disease;C,two-vessel disease;and D,three-vessel disease.Abdominal ultrasonography was performed to determine the presence of a fatty liver and categorize by grade:0,no evidence;1,mild;2,moderate;and 3,severe.We measured not only known CAD risk factors,but also serum insulin,HOMA-index,adiponectin,interleukin-6,tumor necrosis factor-αand high-sensitivity C-reactive protein levels.RESULTS:Of the 134 patients who met the inclusion criteria,82(61.2%)had ultrasonographically diagnosed NAFLD.Among the 46 patients with CAD,37(80.4%)had evidence of a fatty liver.The two groups(A vs B-D)were significantly different in terms of age,total cholesterol,triglycerides,low-density lipoprotein levels and fatty liver.Coronary artery stenosis was strongly associated with fatty liver in a grade-dependent manner(P=0.025).In binary logistic regression,NAFLD was a significant independent predictor of CAD(P=0.03,OR=1.685;95%CI:1.051-2.702).Among the candidate mediators,the serum adiponectin level showed a trend toward lowering based on CAD progression(P=0.071).CONCLUSION:NAFLD is an independent risk factor for CAD in a grade-dependent manner.Moreover,adiponectin might be related to the pathogenesis of NAFLD. | Dae Hee Choi Sung Joon Lee Chang Don Kang Myoung Ok Park Dong Wook Choi Tae Suk Kim Wonho Lee Byung Ryul Cho Yong Hoon Kim Bong-ki Lee Dong Ryeol Ryu Ji Won Lee | 2013 | World Journal of Gastroenterology2013，19，38： | 5 |
| 6 | Wave-Tide-Surge Coupled Simulation for Typhoon Maemi显示文摘The main task of this study focuses on studying the effect of wave-current interaction on currents, storm surge and wind wave as well as effects of current induced wave refraction and current on waves by using numerical models which consider the bottom boundary layer and sea surface roughness parameter for shallow and smooth bed area around Korean Peninsula. The coupled system (unstructured-mesh SWAN wave and ADCIRC) run on the same unstructured mesh. This identical and homogeneous mesh allows the physics of wave-circulation interactions to be correctly resolved in both models. The unstructured mesh can be applied to a large domain allowing all energy from deep to shallow waters to be seamlessly followed. There is no nesting or overlapping of structured wave meshes, and no interpolation is required. In response to typhoon Maemi (2003), all model components were validated independently, and shown to provide a faithful representation of the system's response to this storm. The waves and storm surge were allowed to develop on the continental shelf and interact with the complex nearshore environment. The resulting modeling system can be used extensively for prediction of the typhoon surge. The result show that it is important to incorporate the wave-current interaction effect into coastal area in the wave-tide-surge coupled model. At the same time, it should consider effects of depth-induced wave breaking, wind field, currents and sea surface elevation in prediction of waves. Specially, we found that: (1) wave radiation stress enhanced the current and surge elevation otherwise wave enhanced nonlinear bottom boundary layer decreased that, (2) wind wave was significantly controlled by sea surface roughness thus we cautiously took the experimental expression. The resulting modeling system can be used for hindcasting (prediction) the wave-tide-surge coupled environments at complex coastline, shallow water and fine sediment area like areas around Korean Peninsula. | Byung Ho Choi Byung Il Min Kyeong Ok Kim Jin Hee Yuk | 2013 | China Ocean Engineering2013，27，2： | 4 |
| 7 | Femtosecond laser-mediated anchoring of polymer layers on the surface of a biodegradable metal显示文摘Mg has received much attention as a next-generation implantable material owing to its biocompatibility,bone-like mechanical properties,and biodegradability in physiological environments.The application of various polymer coatings has been conducted in the past to reduce the rapid formation of hydrogen gas and the local change in pH during the initial phase of the chemical reaction with the body fluids.Here,we propose femtosecond(fs)laser-mediated Mg surface patterning for significant enhancement of the binding strength of the coating material,which eventually reduces the corrosion rate.Analyses of the structural,physical,crystallographic,and chemical properties of the Mg surface have been conducted in order to understand the mechanism by which the surface adhesion increases between Mg and the polymer coating layer.Depending on the fs laser conditions,the surface structure becomes rough owing to the presence of several microscaled pits and grooves of nanoporous MgO,resulting in a tightly bonded poly(lactic-co-glycolic acid)(PLGA)layer.The corrosion rate of the PLGA-coated,fs laser-treated Mg is considerably slow compared with the non-treated Mg;the treated Mg is also more biocompatible compared with the non-treated Mg.The fs laser-based surface modification technique offers a simple and quick method for introducing a rough coating on Mg;further,it does not require any chemical treatment,thereby overcoming a potential obstacle for its clinical use. | Jaeho Park Bo-In Park Young Ju Son Sun Hee Lee Seung-Hoon Um Yu-Chan Kim Myoung-Ryul Ok Jeong-Yun Sun Hyung-Seop Han Hojeong Jeon | 2021 | Journal of Magnesium and Alloys2021，9，4： | 2 |
| 8 | Histological improvement following administration of autologous bone marrow‐derived mesenchymal stem cells for alcoholic cirrhosis: a pilot study显示文摘 | Yoon Ok Jang Young Ju Kim Soon Koo Baik Moon Young Kim Young Woo Eom Mee Yon Cho Hong Jun Park So Yeon Park Bo Ra Kim Jae Woo Kim Hyun Soo Kim Sang Ok Kwon Eun Hee Choi Yong Man Kim | 2014 | Liver Int2014，，1： | 2 |
| 9 | Electrical and optical properties of ZnO transparent conducting films by the sol-gel method 显示文摘 | Lee Jin Hong Ko Kyung Hee Park Byung Ok | 2003 | J Cryst Growth2003，247，： | 1 |
| 10 | Target Language Use in Foreign Language Classrooms: Practices and Perceptions of Two Native Speaker Teachers in New Zealand显示文摘 | Sun Hee Ok Kim Catherine Elder | 2008 | Language, Culture and Curriculum2008，，2： | 1 |
| 11 | Purple sweet potato anthocyanins attenuate hepatic lipid accumulation through activating adenosine monophosphate–activated protein kinase in human HepG2 cells and obese mice显示文摘 | Yong Pil Hwang Jae Ho Choi Eun Hee Han Hyung Gyun Kim Ji-Hyang Wee Kyung Ok Jung Kyung Hee Jung Kwang-il Kwon Tae Cheon Jeong Young Chul Chung Hye Gwang Jeong | 2011 | Nutrition Research2011，，12： | 1 |
| 12 | Column-switchinghigh-performance liquid chromatographic method for the determi-nation of zaltoprofen in rat plasma显示文摘 | Sun Ok Choi So Young Uma Sung Hee Jung | 2006 | Journal of ChromatographyB2006，830，： | 1 |
| 13 | Mesenchymal stem cells for enhancing biological healing after meniscal injuries显示文摘The meniscus is a semilunar fibrocartilage structure that plays important roles in maintaining normal knee biomechanics and function.The roles of the meniscus,including load distribution,force transmission,shock absorption,joint stability,lubrication,and proprioception,have been well established.Injury to the meniscus can disrupt overall joint stability and cause various symptoms including pain,swelling,giving-way,and locking.Unless treated properly,it can lead to early degeneration of the knee joint.Because meniscal injuries remain a significant challenge due to its low intrinsic healing potential,most notably in avascular and aneural inner two-thirds of the area,more efficient repair methods are needed.Mesenchymal stem cells(MSCs)have been investigated for their therapeutic potential in vitro and in vivo.Thus far,the application of MSCs,including bone marrow-derived,synovium-derived,and adipose-derived MSCs,has shown promising results in preclinical studies in different animal models.These preclinical studies could be categorized into intra-articular injection and tissueengineered construct application according to delivery method.Despite promising results in preclinical studies,there is still a lack of clinical evidence.This review describes the basic knowledge,current treatment,and recent studies regarding the application of MSCs in treating meniscal injuries.Future directions for MSC-based approaches to enhance meniscal healing are suggested. | Hye Chang Rhim Ok Hee Jeon Seung-Beom Han Ji Hoon Bae Dong Won Suh Ki-Mo Jang | 2021 | World Journal of Stem Cells2021，13，8： | 1 |
| 14 | Continuous l -cysteine production using immobilized cell reactors and product extractors显示文摘 | Ok Hee Ryu Jae Yeong Ju Chul Soo Shin | 1997 | Process Biochemistry1997，，3： | 1 |
| 15 | Identification and characterization of proteins isolated from microvesicles derived from human lung cancer pleural effusions显示文摘 | Jung Ok Park Do‐Young Choi Dong‐Sic Choi Hee Joung Kim Jeong Won Kang Jae Hun Jung Jeong Hwa Lee Jayoung Kim Michael R. Freeman Kye Young Lee Yong Song Gho Kwang Pyo Kim | 2013 | Proteomics2013，，14： | 1 |
| 16 | The stability of L-ATC hydrolase participating in L-cysteine production显示文摘 | Ok Hee Ryu Sea Wha Oh Seung Ku Yoo Chul Soo Shin | 1995 | Biotechnology Letters1995，，3： | 1 |
| 17 | Kinetic properties of a L-cysteine desulfhydrase-deficient mutant in the enzymatic formation of L-cysteine from D,L-ATC显示文摘 | Ki Moon Pae Ok Hee Ryu Hyun Sook Yoon Chul Soo Shin | 1992 | Biotechnology Letters1992，，12： | 1 |
| 18 | Kimchi microflora: history, current status, and perspectives for industrial kimchi production显示文摘 | Ji Young Jung Se Hee Lee Che Ok Jeon | 2014 | Applied Microbiology and Biotechnology2014，，6： | 1 |
| 19 | Clinical application of the BI RADS final assessment to breast sonography in conjunction with mammography显示文摘 | Kyung EK Hee KK Keun OK | 2008 | AJR2008，190，5： | 1 |
| 20 | Column- switching High-performance Liquid Chromatographic Method for the Determination of Zaltoprofen in Rat Plasma显示文摘 | Sun Ok Choi So Young Uma Sung Hee Jung | 2006 | Journal of Chromatography B2006，830，： | 1 |
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