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| 1 | Deferoxamine promotes recovery of traumatic spinal cord injury by inhibiting ferroptosis显示文摘Ferroptosis is an iron-dependent novel cell death pathway. Deferoxamine, a ferroptosis inhibitor, has been reported to promote spinal cord injury repair. It has yet to be clarified whether ferroptosis inhibition represents the mechanism of action of Deferoxamine on spinal cord injury recovery. A rat model of Deferoxamine at thoracic 10 segment was established using a modified Allen's method. Ninety 8-week-old female Wistar rats were used. Rats in the Deferoxamine group were intraperitoneally injected with 100 mg/kg Deferoxamine 30 minutes before injury. Simultaneously, the Sham and Deferoxamine groups served as controls. Drug administration was conducted for 7 consecutive days. The results were as follows:(1) Electron microscopy revealed shrunken mitochondria in the spinal cord injury group.(2) The Basso, Beattie and Bresnahan locomotor rating score showed that recovery of the hindlimb was remarkably better in the Deferoxamine group than in the spinal cord injury group.(3) The iron concentration was lower in the Deferoxamine group than in the spinal cord injury group after injury.(4) Western blot assay revealed that, compared with the spinal cord injury group, GPX4, xCT, and glutathione expression was markedly increased in the Deferoxamine group.(5) Real-time polymerase chain reaction revealed that, compared with the Deferoxamine group, mRNA levels of ferroptosis-related genes Acyl-CoA synthetase family member 2(ACSF2) and iron-responsive element-binding protein 2(IREB2) were up-regulated in the Deferoxamine group.(6) Deferoxamine increased survival of neurons and inhibited gliosis. These findings confirm that Deferoxamine can repair spinal cord injury by inhibiting ferroptosis. Targeting ferroptosis is therefore a promising therapeutic approach for spinal cord injury. | Xue Yao Yan Zhang Jian Hao Hui-Quan Duan Chen-Xi Zhao Chao Sun Bo Li Bao-You Fan Xu Wang Wen-Xiang Li Xuan-Hao Fu Yong Hu Chang Liu Xiao-Hong Kong Shi-Qing Feng | 2019 | Neural Regeneration Research2019，14，3： | 35 |
| 2 | Multiple methods of surgical treatment combined with primary IOL implantation on traumatic lens subluxation/dislocation in patients with secondary glaucoma显示文摘AIM:To describe clinical findings and complications from cases of traumatic lens subluxation/dislocation in patients with secondary glaucoma,and discuss the multiple treating methods of operation combined with primary intraocular lens(IOL)implantation.METHODS:Non-comparativeretrospectiveobservational case series.Participants:30 cases(30 eyes)of lens subluxation/dislocation in patients with secondary glaucoma were investigated which accepted the surgical treatment by author in the Ophthalmology of Xi'an No.4Hospital from 2007 to 2011.According to the different situations of lens subluxation/dislocation,various surgical procedures were performed such as crystalline lens phacoemulsification,crystalline lens phacoemulsification combined anterior vitrectomy,intracapsular cataract extraction combined anterior vitrectomy,lensectomy combined anterior vitrectomy though peripheral transparent cornea incision,pars plana lensectomy combined pars plana vitrectomy,and intravitreal cavity crystalline lens phacofragmentation combined pars plana vitrectomy.And whether to implement trabeculectomy depended on the different situations of secondary glaucoma.The posterior chamber intraocular lenses(PC-IOLs)were implanted in the capsular-bag or trassclerally sutured in the sulus decided by whether the capsular were present.Main outcome measures:visual acuity,intraocular pressure,the situation of intraocular lens and complications after the operations.RESULTS:The follow-up time was 11-36mo(21.4±7.13).Postoperative visual acuity of all eyes were improved;28 cases maintained IOP below 21 mm Hg;2cases had slightly IOL subluxation,4 cases had slightlytilted lens optical area;1 case had postoperative choroidal detachment;4 cases had postoperative corneal edema more than 1wk,but eventually recovered transparent;2 cases had mild postoperative vitreous hemorrhage,and absorbed 4wk later.There was no postoperative retinal detachment,IOL dislocation,and endophthalmitis.CONCLUSION:To take early treatment of traumatic lens subluxation/dislocation in patients with secondary glaucoma by individual surgical plan based on the different eye conditions would be safe and effective,which can effectively control the intraocular pressure and restore some vision. | Rui Wang Chun-Chao Bi Chun-Ling Lei Wen-Tao Sun Shan-Shan Wang Xiao-Juan Dong | 2014 | International Journal of Ophthalmology(English edition)2014，7，2： | 26 |
| 3 | Soil salt leaching under different irrigation regimes: HYDRUS-1D modelling and analysis显示文摘Field irrigation experiments were conducted in the Hetao Irrigation District of Inner Mongolia,China,to study the effects of irrigation regimes on salt leaching in the soil profile.The data were used to calibrate and validate the HYDRUS-1D model.The results demonstrated that the model can accurately simulate the water and salt dynamics in the soil profile.The HYDRUS-1D model was then used to simulate 15 distinct irrigation scenarios.The results of the simulation indicated that irrigation amount did not have a significant effect on soil water storage but that increases in irrigation amount could accelerate salt leaching.However,when the irrigation amount was larger than 20 cm,the acceleration was not obvious.Compared with irrigating only once,intermittent irrigation had a better effect on increasing soil water storage and salt leaching,but excessive irrigation times and intervals did not improve salt leaching.In addition,we found that the irrigation regime of 20 cm,irrigated twice at 1-d intervals,might significantly increase salt leaching in the plough layer and decrease the risks of deep seepage and groundwater contamination. | WenZhi ZENG Chi XU JingWei WU JieSheng HUANG | 2014 | Journal of Arid Land2014，6，1： | 20 |
| 4 | Using specific secondary metabolites as markers to evaluate allelopathic potentials of rice varieties and individual plants显示文摘It is a key of the breeding of ailelopathic rice cultivars to evaluate and screen few accessions with ailelopathic traits from numerous rice accessions and individual plants. Rice varieties and individual plants with ailelopathic traits demonstrated their ailelopathic effects by producing and releasing specific secondary metabolites into environment. Therefore, using specific secondary metabolites as markers, the ailelopathic potentials of rice varieties and individual plants could be evaluated by HPLC. The ailelopathic potentials of 3000 rice accessions and some individual plants of F3 and F4 were evaluated by this method in 1 a. If these accessions and plants were evaluated by the traditional method in the field, it would take more than 10 a, furthermore, the breeding process of ailelopathic rice cultivars would be directed and monitored by this method. Isolation and structural identification of specific secondary metabolites was done by LC/MS coupling 1H and 13C NMR. It revealed that allelochemicals | KONG Chuihua XU Xiaohua HU Fei CHEN Xionghui LING Bing TAN Zhongwen | 2002 | Chinese Science Bulletin2002，47，10： | 17 |
| 5 | Biotechnology Applications of Plant Callus Cultures显示文摘In ethnopharmacology, and especially in traditional Chinese medicine, medicinal plants have been used for thousands of years. Similarly, agricultural plants have been used throughout the history of mankind. The recent development of the genetic engineering of plants to produce plants with desirable features adds a new and growing dimension to humanity’s usage of plants. The biotechnology of plants has come of age and a plethora of bioengineering applications in this context have been delineated during the past few decades. Callus cultures and suspension cell cultures offer a wide range of usages in pharmacology and pharmacy (including Chinese medicine), as well as in agriculture and horticulture. This review provides a timely overview of the advancements that have been made with callus cultures in these scientific fields. Genetically modified callus cultures by gene technological techniques can be used for the synthesis of bioactive secondary metabolites and for the generation of plants with improved resistance against salt, draft, diseases, and pests. Although the full potential of callus plant culture technology has not yet been exploited, the time has come to develop and market more callus culture-based products. | Thomas Efferth | 2019 | Engineering2019，5，1： | 16 |
| 6 | 不同施氮水平下枸杞主要次生代谢产物与多糖的关系研究(英文)显示文摘[Objective] The aim of this study is to investigate the optimum application amount of nitrogen in Lycium barbarum based on considering the relationship between main secondary metabolites and polysaccharide.[Method]Under field conditions,the effects of different application amounts of nitrogen on main secondary metabolites of betaine,carotenoid and flavone of Lycium barbarum and the relationship between main secondary metabolites and polysaccharide.[Result] The main secondary metabolites of betaine,carotenoid and flavone of Lycium barbarum varied under different application amounts of nitrogen.The proper application amount of nitrogen(600-900 kg/hm2)was beneficial to the formation and accumulation of secondary metabolites such as carotenoids.Correlation analysis results showed that polysaccharide were negatively correlated with betaine,carotenoid and flavone at significant probability level.[Conclusion]Considering the relationship between the output and quality of the fruits of Lycium barbarum,the optimum nitrogen application amount should be 600-900 kg/hm2. | 康建宏 吴宏亮 杨涓 杨剑涛 | 2008 | Agricultural Science & Technology2008，9，5： | 15 |
| 7 | DESIGN AND PREPARATION OF SILICON NITRIDE COMPOSITE WITH HIGH FRACTURE TOUGHNESS AND NACRE STRUCTURE显示文摘DESIGNANDPREPARATIONOFSILICONNITRIDECOMPOSITEWITHHIGHFRACTURETOUGHNESSANDNACRESTRUCTUREYHuang;H.NHao;Y.L.ChenandB.L.Zhou(1)De... | Y Huang H.N Hao Y.L. Chen and B.L.Zhou (1)Department of Materials Science and Engineering, Tsinghua University,Beijing 100084, China 2)Institute of Metal Research, Chinese Academy of Sciences,Shenyang 110015, China ) | 1996 | Acta Metallurgica Sinica(English Letters)1996，9，6： | 12 |
| 8 | Pollution characteristics of atmospheric fine particles and their secondary components in the atmosphere of Shenzhen in summer and in winter显示文摘Two field measurements for atmospheric fine particles were conducted in Baoan district of Shenzhen during the summer and winter in 2004. Totally 30 sets of 24 h samples were collected, and then the mass concentrations and chemical compositions were determined. The seasonal varia- tions and secondary pollution characteristics of fine particles during the sampling periods were dis-cussed with meteorological factors. The results show that seasonal variations of atmospheric particles are significant in Shenzhen. The average mass concentrations of PM2.5 and PM10 in summer were 35 μg·m-3 and 57 μg·m-3, respectively, and those in winter were 99 μg·m-3 and 135 μg·m-3, respec-tively. The concentrations of both PM2.5 and PM10 in winter increased 184% and 137%, respectively, compared to those in summer. PM2.5 accounted for 61% and 75% of PM10 in summer and in winter, respectively, indicating severe fine particle pollution in Shenzhen. During the summer and winter sampling periods, the mean OC/EC ratios were 3.4 and 1.6, respectively. The estimated secondary organic carbon (SOC) averagely accounted for 56% and 6% of the total OC in summer and in winter, respectively, which implies a major contribution of SOC to OC in summer. During the continuous high temperature period in summer, both the concentrations and fractions of secondary aerosol compo-nents in PM2.5 were highly elevated, suggesting severe secondary pollution again. The prevailing wind was from South China Sea in summer, and the air quality was good. The prevailing wind in winter was from China's Mainland to the north, and the polluted air mass led to poor air quality. | NIU Yuwen1,2,HE Lingyan1,2,HU Min2,ZHANG Jing2 & ZHAO Yunliang2 1. Shenzhen Graduate School of Peking University,Shenzhen 518055,China 2. State Joint Key Laboratory of Environmental Simulation and Pollution Control,College of Environmental Sciences,Peking University,Beijing 100871,China | 2006 | Science China Chemistry2006，49，5： | 12 |
| 9 | Characterizing oxygenated volatile organic compounds and their sources in rural atmospheres in China显示文摘Oxygenated volatile organic compounds(OVOCs) are important precursors and products of atmospheric secondary pollution. The sources of OVOCs, however, are still quite uncertain,especially in the atmosphere with much pollution in China. To study the sources of OVOCs in rural atmospheres, a proton transfer reaction mass spectrometry(PTR-MS) was deployed at a northern rural site(WD) and a southern rural site(YMK) in China during the summer of 2014 and 2016, respectively. The continuous observation showed that the mean concentration of TVOCs(totally 17 VOCs) measured at WD(52.4 ppbv) was far higher than that at YMK(11.1 ppbv), and the OVOCs were the most abundant at both the two sites. The diurnal variations showed that local sources of OVOCs were still prominent at WD, while regional transport influenced YMK much. The photochemical age-based parameterization method was then used to quantitatively apportion the sources of ambient OVOCs. The anthropogenic primary sources at WD and YMK contributed less(2%–16%) to each OVOC species. At both the sites, the atmospheric background had a dominant contribution(~ 50%) to acetone and formic acid, while the anthropogenic secondary formation was the main source(~ 40%) of methanol and MEK. For acetaldehyde and acetic acid, the biogenic sources were their largest source(~ 40%) at WD, while the background(39%) and anthropogenic secondary formation(42%) were their largest sources at YMK, respectively. This study reveals the complexity of sources of OVOCs in China, which urgently needs explored further. | Yu Han Xiaofeng Huang Chuan Wang Bo Zhu Lingyan He | 2019 | Journal of Environmental Sciences2019，31，7： | 12 |
| 10 | Review of tumoral calcinosis: A rare clinico-pathological entity显示文摘Tumoral calcinosis(TC) has long been a controversial clinico-pathological entity. Its pathogenesis and genetic background have been gradually unravelled since its first description in 1943. According to the presence or absence of an underlying calcifying disease process, TC has been divided into primary and secondary varieties. Two subtypes of the primary variety exist; a hyperphosphatemic type with familial basis represented by mutations in Gal NAc transferase 3 gene(GALNT3), KLOTHO or Fibroblast growth factor 23(FGF23) genes, and a normo-phosphatemic type with growing evidence of underlying familial base represented by mutation in SAMD9 gene. The secondary variety is mainly associated with chronic renal failure and the resulting secondary or tertiary hyperparathyroidism. Diagnosis of TC relies on typical radiographic features(on plain radiographs and computed tomography) and the biochemical profile. Magnetic resonance imaging can be done in difficult cases, and scintigraphy reflects the disease activity. Treatment is mainly surgical for the primary variety; however, a stage-oriented conservative approach using phosphate binders, phosphate restricted dietsand acetazolamide should be considered before the surgical approach is pursued due to the high rate of recurrences and complications after surgical intervention. Medical treatment is the mainstay for treatment of the secondary variety, with failure warranting subtotal or total parathyroidectomy. Surgical intervention in these patients should be kept as a last resort. | Ibrahim Fathi Mahmoud Sakr | 2014 | World Journal of Clinical Cases2014，2，9： | 11 |
| 11 | Investigation on the Oscillating Buoy Wave Power Device显示文摘An oscillating buoy wave power device (OD) is a device extracting wave power by an oscillating buoy. Being excitedby waves, the buoy heaves up and down to convert wave energy into electricity by means of a mechanical or hydraulic de-vice. Compared with an Oscillating Water Column (OWC) wave power device, the OD has the same capture width ratio as the OWC does, but much higher secondary conversion efficiency. Moreover, the chamber of the OWC, which is the mostexpensive and difficult part to be built, is not necessary for the OD, so it is easier to construct an OD. In this paper, a nu-merical calculation is conducted for an optimal design of the OD firstly, then a model of the device is built and, a model testis carded out in a wave tank. The results show that the total efficiency of the OD is much higher than that of the OWC andthat the OD is a promising wave power device. | 苏永玲 游亚戈 郑永红 | 2002 | China Ocean Engineering2002，17，1： | 11 |
| 12 | 美国《初等和中等教育法案》的历史演变与分析显示文摘本文介绍并分析了美国《初等和中等教育法案》的演变过程,指出了ESEA法案中需要进一步解决的问题。 | 李春黎 | 2006 | 外国中小学教育2006，，1： | 10 |
| 13 | Evolution of the CBM reservoir-forming dynamic system with mixed secondary biogenic and thermogenic gases in the Huainan Coalfield,China显示文摘The secondary biogenic gas is an important original type of the coalbed methane (CBM) in China. Based on the analyses of sedimentary and burial history of the Permian coal-bearing strata, combined with thermal history and gas generation process of coals, the CBM reservoir-forming dynamic system with mixed secondary biogenic and thermogenic gases in the Huainan Coalfield is subdivided into four evolutionary stages as follows: (i) shallowly-buried peat and early biogenic gas stage; (ii) deeply buried coal seams and thermogenic gas stage; (iii) exhumation of coal-bearing strata and adsorbed gas lost stage; and (iv) re-buried coal-bearing strata and secondary biogenic gas supplement stage. The Huainan CBM reservoir-forming model has the features of the basin-centered gas accumulation. The evolution of the reservoir-forming dynamic system proves that the thermogenic gas is not the main gas source for the Huainan CBM reservoir. Only the secondary biogenic gases as an additional source replenish into the coal bed after basin-uplift, erosional unroofing and subsequent scattering of thermogenic gases. Then this kind of mixed CBM reservoirs can be formed under suitable conditions. | ZHANG Hong CUI Yongjun TAO Mingxin PENG Gelin JIN Xianglan LI Guihong | 2005 | Chinese Science Bulletin2005，50，S1： | 10 |
| 14 | Frequency, localization, and types of gastrointestinal stromal tumor-associated neoplasia显示文摘BACKGROUND In recent years,increasing evidence of second neoplasms associated with gastrointestinal stromal tumors(GIST)has been found.Numerous case reports,mostly retrospective studies and a few reviews,have been published.To our knowledge,however,no systematic review or meta-analysis of the existing data has been performed so far.AIM To prepare a compilation,as complete as possible,of all reported second tumor entities that have been described in association with GIST and to systematically analyze the published studies with regard to frequency,localization,and types of GIST-associated neoplasms.METHODS The MEDLINE and EBSCO databases were searched for a combination of the keywords GIST/secondary,synchronous,coincident/tumor,neoplasm,and relevant publications were selected by two independent authors.RESULTS Initially,3042 publications were found.After deletion of duplicates,1631 remained,and 130 papers were selected;22 of these were original studies with a minimum of 20 patients,and 108 were case reports.In the 22 selected studies,comprising a total number of 12050 patients,an overall rate of GIST-associated neoplasias of 20%could be calculated.Most second neoplasias were found in the gastrointestinal tract(32%)and in the male and female urogenital tract(30%).The specific risk scores of GISTs associated with other tumors were significantly lower than those without associated neoplasias.CONCLUSION In this first systematic review,we could confirm previously reported findings of a more than coincidental association between GIST and other neoplasias.The question whether there is an underlying causal association will need further investigation.Our data suggest that even GIST with a very low risk of disease progression should prompt screening for second neoplasia and subsequent frequent controls or extended staging. | Johanna Waidhauser Anne Bornemann Martin Trepel Bruno Markl | 2019 | World Journal of Gastroenterology2019，25，30： | 10 |
| 15 | Phosphorylation of LTF1, an MYB Transcription Factor in Populus, Acts as a Sensory Switch Regulating Lignin Biosynthesis in Wood Cells显示文摘Lignin is specifically deposited in plant secondary cell walls,and initiation of lignin biosynthesis is regulated by a variety of developmental and environmental signals.However,the mechanisms governing the regulation of lignin biosynthesis remain to be elucidated.In this study,we identified a lignin biosynthesis-associated transcription factor(LTF)from Populus,LTF1,which binds the promoter of a key lignin biosynthetic gene encoding 4-coumarate-CoA ligase(4CL).We showed that LTF1 in its unphosphorylated state functions as a regulator restraining lignin biosynthesis.When LTF1 becomes phosphorylated by PdMPK6 in response to external stimuli such as wounding,it undergoes degradation through a proteasome pathway,resulting in activation of lignification.Expression of a phosphorylation-null mutant version of LTF1 led to stable protein accumulation and persistent attenuation of lignification in wood cells.Taken together,our study reveals a mechanism whereby LTF1 phosphorylation acts as a sensory switch to regulate lignin biosynthesis in response to environmental stimuli.The discovery of novel modulators and mechanisms modifying lignin biosynthesis has important implications for improving the utilization of cell-wall biomass. | Jinshan Gui Laifu Luo Yu Zhong Jiayan Sun Toshiaki Umezawa Laigeng Li | 2019 | Molecular Plant2019，12，10： | 10 |
| 16 | Role of band ligation for secondary prophylaxis of variceal bleeding显示文摘AIM To summarize and critically examine the role of band ligation in secondary prophylaxis of variceal bleeding in patients with cirrhosis. METHODS A literature review was performed using the MEDLINE and PubM ed databases. The search terms consisted of the words 'endoscopic band ligation' OR 'variceal band ligation' OR 'ligation' AND 'secondary prophylaxis' OR 'secondary prevention' AND 'variceal bleeding' OR 'variceal hemorrhage' AND 'liver cirrhosis'. The data collected from relevant meta-analyses and from the most recent randomized studies that were not included in these meta-analyses were used to evaluate the role of endoscopic band ligation in an effort to demonstrate the most recent advances in the treatment of esophageal varices. RESULTS This study included 11 meta-analyses published from 2002 to 2017 and 10 randomized trials published from 2010 to 2017 that evaluated the efficacy of band ligation in the secondary prophylaxis of variceal bleeding. Overall, the results proved that band ligation was superior to endoscopic sclerotherapy. Moreover, the use of β-blockers in combination with band ligation increased the treatment effectiveness, supporting the current recommendations for secondary prophylaxis of variceal bleeding. The use of transjugular intrahepatic portosystemic shunt was superior to combination therapy regarding rebleeding prophylaxis, with no difference in the survival rates; however, the results concerning the hepatic encephalopathy incidence were conflicting. Recent advances in the management of secondary prophylaxis of variceal bleeding have targeted a decrease in portal pressure based on the pathophysiological mechanisms of portal hypertension.CONCLUSION This review suggests that future research should be conducted to enhance current interventions and/or to develop innovative treatment options with improved clinical endpoints. | Ioanna Aggeletopoulou Christos Konstantakis Spilios Manolakopoulos Christos Triantos | 2018 | World Journal of Gastroenterology2018，24，26： | 9 |
| 17 | Primary and secondary control in DC microgrids: a review显示文摘With the rapid development of power electronics technology, microgrid(MG) concept has been widely accepted in the field of electrical engineering. Due to the advantages of direct current(DC)distribution systems such as reduced losses and easy integration with energy storage resources, DC MGs have drawn increasing attentions nowadays. With the increase of distributed generation, a DC MG consisting of multiple sources is a hot research topic. The challenge in such a multi-source DC MG is to provide voltage support and good power sharing performance. As the control strategy plays an important role in ensuring MG’s power quality and efficiency, a comprehensive review of the state-of-art control approaches in DC MGs is necessary. This paper provides an overview of the primary and secondary control methods under the hierarchical control architecture for DC MGs. Specifically,inner loop and droop control approaches in primary control are reviewed. Centralized, distributed and decentralized approach based secondary control is discussed in details.Key findings and future trends are also presented at last. | Fei GAO Ren KANG Jun CAO Tao YANG | 2019 | Journal of Modern Power Systems and Clean Energy2019，7，2： | 8 |
| 18 | Research Progress of Medicinal Secondary Metabolites and Gene Cloning of Dendrobium officinale显示文摘Dendrobium officinale is one of the most precious medicinal plants in China. Its main medicinal ingredients are its secondary metabolites. However,it has the characteristics of limited sources,low active ingredient content and high cost,limiting the use of D. officinale.Studying the network structure and rate-limiting steps of secondary metabolites of medicinal components of D. officinale,analyzing the secondary metabolic synthesis process,mastering the production rules of its medicinal components and carrying out gene cloning or biosynthesis,etc.are of great significance for the rational development and utilization of D. officinale resources. This paper briefly reviews the progress of the research on the secondary metabolites of D. officinale,including the detection and identification of metabolites and the identification and cloning of key metabolic enzymes. | Ye LIANG Caihua ZOU Jindu LI Shilong LI Tianzi LI | 2019 | Medicinal Plant2019，10，3： | 8 |
| 19 | Simulation of secondary aerosols over North China in summer显示文摘The comparisons of observed and simulated NOx, CO, O3, NH3, HNO3, SO2 and PM2.5 indicate that CMAQ model can simulate variations of pollutants over North China well.Moreover, the model results show that high NH3 is in Hebei, Henan and Shandong provinces,with average concentration of (30-35)×10-9. The results of the sensitive experiment indicate that high concentration of NH3 has the efficiency of the production of secondary sulfate aerosol increase by more than 30%, especially at the juncture of Handan, Anyang and Changzhi that increased by 50%. In addition, NH3 also produces secondary ammonia and nitrate aerosol, and the sum of them is approximately equal to sulfate aerosol. The height of planetary boundary layer (PBL) in Beijing is higher in daytime, with average height of 1500 m at noon. This makes SO2,NH3 and HNO3 transported into upper PBL of 850 hPa. The high secondary sulfate, and ammonia and nitrate aerosol happen in the upper and lower PBL, respectively. Because PM2.5 lifetime is relatively long, it can be transported into the middle troposphere to form a thick aerosol layer,which is the arched roof of aerosol. The model result suggests that if the aerosol concentration in North China would be controlled, the reduction of NH3 emission is one of efficient ways besides the reduction of primary SO2, NOx and aerosol emission. | LIU Yu LI Weiliang ZHOU Xiuji | 2005 | Science China Earth Sciences2005，48，z2： | 8 |
| 20 | Modeling and prediction of children’s growth data via functional principal component analysis显示文摘We use the functional principal component analysis(FPCA) to model and predict the weight growth in children.In particular,we examine how the approach can help discern growth patterns of underweight children relative to their normal counterparts,and whether a commonly used transformation to normality plays any constructive roles in a predictive model based on the FPCA.Our work supplements the conditional growth charts developed by Wei and He(2006) by constructing a predictive growth model based on a small number of principal components scores on individual's past. | HU Yu HE XuMing TAO Jian SHI NingZhong | 2009 | Science China Mathematics2009，52，6： | 8 |
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