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| 1 | 骨质疏松性椎体骨折分期、分型及治疗研究进展显示文摘随着社会人口老龄化,骨质疏松性椎体骨折(osteoporotic vertebral fracture,OVF)已逐渐成为老年人的一种常见疾病。OVF常由微小外力(低能量损伤)导致,多数为椎体轻度压缩骨折,少数因骨质疏松严重或治疗不恰当,可出现椎体爆裂骨折、椎体严重塌陷、脊柱后凸畸形,不仅可导致脊髓神经损害症状,还可影响患者心肺及胃肠道功能, | 梁德 唐永超 江晓兵 张顺聪 杨志东 | 2016 | 中国脊柱脊髓杂志2016,26,3: | 41 |
| 2 | 骨质疏松性椎体压缩骨折PVP或PKP术后邻近椎体再骨折的危险因素研究进展显示文摘伴随着我国进入老龄化社会,骨质疏松性椎体压缩性骨折(osteoporotic vertebral compression fracture,OVCF)发病率越来越高。经皮椎体成形术(percutaneous vertebroplasty,PVP)及经皮椎体后凸成形术(percutaneous kyphoplasty,PKP)已经成为治疗OVCF的主要方法,它以创伤小、缓解疼痛明显、显著提高患者生存质量、并发症少等优点被广泛应用于临床。 | 杜亚雷 何保玉 滕涛 | 2016 | 实用医学杂志2016,32,9: | 47 |
| 3 | Prevalence of osteoporotic vertebral fracture among community-dwelling elderly in Shanghai显示文摘To the Editor:Osteoporosis is becoming a common,serious,and costly health problem,which causes over nine million fractures annually worldwide.[1] Currently,osteoporotic fractures are a considerable burden to public health services and have fairly high morbidity and mortality.[2] Vertebral fractures are the most common osteoporotic fracture and may lead to a high risk of further fracture and could be prevalent in both females and males.[3] Ling et al[4] and Ms.OS studies[5] evaluated the prevalence of vertebral fractures in Beijing and Hong Kong,respectively.However,our knowledge of the descriptive epidemiology and risk factors for vertebral fracture in China still remains poor. | Chao Gao Yang Xu Li Li Wen-Qin Gu Chun-Tao Yi Qiong Zhu Hong-An Gu Bi-Hua Chen Qing-Qing Wang Feng Tang Ju-Liang Xu Jian-Miao Hou Hui-Jiang Song Hui Wang Zhi-Liang Wang Zhen-Lin Zhang | 2019 | Chinese Medical Journal2019,,14: | 31 |
| 4 | 椎体成形术后手术椎体再塌陷的危险因素显示文摘随着我国人口老龄化的发展,骨质疏松性椎体压缩骨折(osteoporotic vertebral compression fracture,OVCF)的发生越来越多。经皮椎体成形术(percutaneous vertebroplasty,PVP)和经皮椎体后凸成形术(percutaneous kyphoplasty,PKP)是OVCF主要外科治疗方法 ,通过将填充材料注入椎体来强化病椎,从而迅速缓解疼痛,恢复椎体高度,改善生活质量[1、2],降低OVCF的病死率[3]。 | 张煜 张绍东 | 2016 | 中国脊柱脊髓杂志2016,26,5: | 25 |
| 5 | 射频联合银质针治疗骨质疏松性胸腰椎压缩性骨折后遗痛显示文摘椎体骨质疏松性压缩性骨折(osteoporotic vertebral compression fracture,OVCF)是老年人的常见病,多发病,由于慢性疼痛伴活动障碍使患者长期卧床,加剧其呼吸、循环消化等系统功能衰退,Kado等人报道,老年OVCF患者5年内病死率高达23%~34%,明显高于同龄人。传统的药物、理疗往往疗效不佳或康复时间较长。 | 张赢 关彦彦 李凌超 黄帅 郭佳 于晓莹 | 2016 | 中国疼痛医学杂志2016,22,3: | 22 |
| 6 | 经皮椎体后凸成形术不同手术入路的应用现状显示文摘骨质疏松性椎体压缩骨折(osteoporotic vertebral compression fractures,OVCFs)在老年人群,尤其是老年女性群体中的发病率很高,常发生在胸腰段,最常见的临床症状是剧烈的腰背部疼痛,严重影响患者的生活质量[1、2]。随着社会人口老龄化的加剧,其发病率逐年增加[3、4],经皮椎体后凸成形术(percutaneous kyphoplasty,PKP)可以很好地缓解OVCFs引起的疼痛. | 邓志洋 武汉 刘晨琪 李永博 唐晓东 孙岩 | 2017 | 中国脊柱脊髓杂志2017,27,3: | 18 |
| 7 | 唑来膦酸治疗老年患者经皮椎体后凸成形术后椎体再骨折的短期疗效显示文摘骨质疏松症是引起老年人腰背疼痛的常见原因之一,骨质疏松症并发症——椎体压缩性骨折成为老年人常见病之一。以往的保守治疗方法需卧床2-3月,这不仅加速骨量的流失还可能发生卧床并发症。经皮椎体后凸成形术(percutaneous kyphoplasty,PKP)是治疗老年骨质疏松性胸腰椎骨折(osteoporostic vertebral compressive fracture,OVCF)的有效方法,有学者发现PKP术后椎体再骨折发生率为12.5%,如何减少PKP术后再骨折发生率成为关注的重点。 | 刘新奇 叶福生 王永光 童培建 | 2015 | 中华骨质疏松和骨矿盐疾病杂志2015,8,1: | 17 |
| 8 | 经皮椎体后凸成形术治疗老年骨质疏松性椎体压缩骨折显示文摘骨质疏松性椎体压缩骨折(osteoporotic vertebral compressive fractures,OVCF)好发于老年人脊柱的T10-L2节段,约占老年人全身骨折的3%[1]。传统的治疗方法主要依靠卧床休息、垫枕复位及止痛、抗骨质疏松药物保守治疗,但往往疼痛缓解效果不佳,且复位高度也不理想[2]。 | 夏维财 | 2015 | 中国微创外科杂志2015,15,3: | 15 |
| 9 | 经皮椎体成形术后无症状性骨水泥肺栓塞7年随访结果及文献回顾显示文摘椎体成形术是治疗骨质疏松性椎体骨折最常用的一种微创手术,尽管其安全有效,但其并发症骨水泥渗漏也相对常见,尤其骨水泥渗漏引起的肺栓塞是其术后一种严重的、潜在致命风险的并发症[1~3],逐渐引起临床关注,但长期随访报道较少。 | 唐永超 梁德 江晓兵 张顺聪 姚珍松 杨志东 莫凌 | 2015 | 中国脊柱脊髓杂志2015,25,11: | 14 |
| 10 | Endovascular treatment of extracranial vertebral artery stenosis显示文摘Percutaneous angioplasty and stenting for the treatment of extracranial vertebral artery(VA) stenosis seems a safe,effective and useful technique for resolving symptoms and improving blood flow to the posterior circulation,with a low complication rate and good long-term results.In patients with severe tortuosity of the vessel,stent placement is a real challenge.The new coronary balloon-expandable stents may be preferred.A large variability of restenosis rates has been reported.Drug-eluting stents may be the solution.After a comprehensive review of the literature,it can be concluded that percutaneous angioplasty and stenting of extracranial VA stenosis is technically feasible,but there is insufficient evidence from randomized trials to demonstrate that endovascular management is superior to best medical management. | Burak Kocak Bora Korkmazer Civan Islak Naci Kocer Osman Kizilkilic | 2012 | World Journal of Radiology2012,4,9: | 13 |
| 11 | Bilateral medial medullary infarction with distal stenosis of hypoplastic vertebral artery显示文摘To the Editor:Bilateral medial medullary infarction(MMI)is a rare stroke subtype.[1]usually leads to quadriplegia,sensory disturbance,hypoglossal palsy,bulbar paralysis,etc.[2]We encountered a patient with rapidly progressive tetraparesis and diffusion-weighted imaging(DWI)exhibited a“heart appearance”sign in the bilateral ventral medulla.Computed tomography angiography(CTA)demonstrated that the left vertebral artery(VA)was hypoplastic and there was an atherosclerotic stenosis in the V4 segment. | Jie-Ping Lu Yan Wu Fang Xiao Huai-Yu Li Qi-Qiang Tang | 2019 | Chinese Medical Journal2019,,8: | 13 |
| 12 | 椎动脉型颈椎病诊断方法研究进展显示文摘椎动脉型颈椎病(cevical spondylosis of vertebral artery type,CSA)是各种机械性与动力性因素致使椎动脉受刺激或压迫,以致血管狭窄、折曲而造成以椎-基底动脉供血不足(VBI)为主要症状的综合征。CSA是颈椎病中常见类型,发病率仅次于神经根型。其发病机制主要有3点:1动力性因素,由于椎节失稳后钩椎关节松动变位而波及侧方上下横突孔,出现轴向或侧向移位刺激或压迫椎动脉,引起痉挛、狭窄或折曲。 | 林益良 莫深 卢家灵 黄发明 张中文 盛国全 冼新源 方培 | 2015 | 实用医技杂志2015,22,8: | 9 |
| 13 | 高压氧在骨科疾病中的应用研究进展显示文摘随着高压氧医学的发展,高压氧疗法在临床疾病方面的应用越来越广泛。现就其在骨科疾病中的应用研究综述如下。
1颈腰椎疾病
1.1颈椎病
1.1.1椎动脉型颈椎病:椎动脉型颈椎病(vertebral artery type of cervical spondylosis,VA-CS)是由于颈椎不稳,退变,骨刺直接刺激、压迫椎动脉,或者由于刺激了椎动脉颈椎关节囊韧带和椎动脉壁周围的交感神经引起的反射性椎动脉痉挛而导致椎动脉供血不足的一种疾病。 | 李红玲 马维 | 2014 | 中国康复医学杂志2014,29,10: | 8 |
| 14 | 全脊椎截骨术治疗严重脊柱畸形的若干思考显示文摘重度脊柱畸形存在多平面失平衡,畸形严重且僵硬,临床治疗十分困难。1922年,Mac Lennan[1]首次提出顶椎切除可以用于治疗僵硬型脊柱侧凸畸形,这是全脊椎截骨术(vertebral column resection,VCR)的理论雏形。1979年,Leatherman等[2]首次报告前后路联合椎体切除矫正严重脊柱多平面畸形,Bradford等[3]于1997年报告了该术式治疗僵硬性冠状面失衡的临床疗效。 | 朱泽章 邱勇 | 2016 | 中国脊柱脊髓杂志2016,26,1: | 6 |
| 15 | Computed tomography-based finite element analysis to assess fracture risk and osteoporosis treatment显示文摘Finite element analysis(FEA) is a computer technique of structural stress analysis and developed in engineering mechanics. FEA has developed to investigate structural behavior of human bones over the past 40 years. When the faster computers have acquired, better FEA, using 3-dimensional computed tomography(CT) has been developed. This CT-based finite element analysis(CT/FEA) has provided clinicians with useful data. In this review, the mechanism of CT/FEA, validation studies of CT/FEA to evaluate accuracy and reliability in human bones, and clinical application studies to assess fracture risk and effects of osteoporosis medication are overviewed. | Kazuhiro Imai | 2015 | World Journal of Experimental Medicine2015,5,3: | 6 |
| 16 | Methods of predicting vertebral body fractures of the lumbar spine显示文摘Lumbar vertebral body(VB) fractures are increasingly common in an ageing population that is at greater risk of osteoporosis and metastasis. This review aims to identify different models, as alternatives to bone mineral density(BMD), which may be applied in order to predict VB failure load and fracture risk. The most representative models are those that take account of normal spinal kinetics and assess the contribution of the cortical shell to vertebral strength. Overall, predictive models for VB fracture risk should encompass a range of important parameters including BMD, geometric measures and patient-specific factors. As interventions like vertebroplasty increase in popularity for VB fracture treatment and prevention, such models are likely to play a significant role in the clinical decision-making process. More biomechanical research is required, however, to reduce the risks of post-operative adjacent VB fractures. | Gurudattsingh B Sisodia | 2013 | World Journal of Orthopedics2013,4,4: | 6 |
| 17 | Reinforcing effect of calcium sulfate cement bovine bone morphogenetic protein on vertebral in the rabbit model of osteoporosis显示文摘Objective:To observe reinforcing effect of calcium sulfate cement(CSC) bovine bone morphogenetic protein(bBMP) on vertebral in the rabbit model of osteoporosis.Methods:A total of 48 New Zealand white rabbits were randomly divided into group Ⅰ(blank control group),groupⅡ(CSC injection group),group Ⅲ(CSC/bBMP injection group) and control group.White rabbit osteoporosis model was established rapidly by using castration mcthod+methylprcdnisolone candidate.After modeling,groups Ⅱ.Ⅲ were given corresponding vertebral body injection material,and 4 animals were sacrificed respectively at 24 h,6 weeks,12 weeks after vertebral plasty.Tissue pathological status,vertebral mineral density and vertebral body bone mechanical strength were observed.Results:Vertebral body structure form was normal in the groups Ⅱand Ⅲ.Trabecular bone coarsens,connection and repair were observed in micro fracture and bone defects,bone trabecular connectivity was superior to group I significantly;vertebral body compression strength in the group I was on the decline,vertebral compression strength in the groups Ⅱ and Ⅲ was on the rise,the largest vertebra.Postoperative BMC and BMD in groups Ⅱand Ⅲ were incresed,and significantly higher than group I after 6 weeks(P<0.05),BMC and BMD in group Ⅲ after 12 weeks were higher than the other three groups.Conclusion:Compound bBMP CSC has good bone induction.It can improve the three-dimensional construction effect for osteoporosis vertebral trabecula,and can significantly improve the vertebral strength,as a vertebral packing material with good application prospect. | Jie Zhang Chen Sheng-Guo Kaken.Habaerxi Shawuti.Alimujiang Yu Chen Ming-Zhen Peng Rong Yue Yu-Lian Wu De-Quan Wang Yu-Ming Chen | 2014 | Asian Pacific Journal of Tropical Medicine2014,7,5: | 4 |
| 18 | 经皮椎体后凸成形术配合中药治疗骨质疏松性椎体压缩性骨折的研究进展显示文摘经皮椎体后凸成形术(percutaneous kypholasty,PKP)是一种治疗骨质疏松性椎体压缩性骨折(osteoporotic vertebral compression fracture,OVCF)的微创技术,具有操作简单、经济、缓解疼痛迅速、尽可能恢复椎体高度及强度等优点,现已被广泛运用于临床。然而,PKP主要解决的是骨折椎体引起的疼痛问题,引起椎体骨折的原因——骨折疏松的病理体质,并没有得到根本改变,其余椎体仍存在再发骨折的风险。近年来,中药在骨质疏松的防治上有了新的研究进展, | 邱芬 陈宗雄 | 2017 | 基层医学论坛2017,21,8: | 4 |
| 19 | 椎体成形联用唑来膦酸治疗脊椎转移性疼痛的疗效分析显示文摘脊柱部位原发肿瘤或继发浸润所致的骨相关事件(Skeletal-related events,SREs)包括转移性脊柱溶骨性病变(osteolytic spinal metastases,OSM)和肿瘤相关性脊柱压缩性骨折(malignant vertebral compression fractures,MVCF)[1,2]。根据OSM及MVCF的病理生理特征,肿瘤相关性SREs治疗应兼顾病因(抑制溶骨破坏、增加椎体强度及稳定)及症状(缓解SREs所致的剧烈疼痛)的针对性处理【3]。尽管既往研究己证实经皮穿刺椎体成形术(percutaneousvertebroplasty,PVP)可有效治疗脊柱压缩性骨折且具有微创、高效镇痛、快速起效及改善脊柱机械稳定性的优点,但仍未能从病因上抑制OSM。 | 陈黔 王大寿 潘奇 张亮 钱黎 何猛 陈艳 孙文阳明 罗金玉 淦勇 肖阳 吴黔鸣 | 2016 | 中国疼痛医学杂志2016,22,7: | 4 |
| 20 | Vertebral fracture assessment:Current research status and application in patients with kyphoplasty显示文摘Imaging of the spine is of paramount importance for the recognition of osteoporotic vertebral fractures(VFs), and standard radiography(SR) of the spine is the suggested diagnostic method but is not routinely used because of the cost and radiation exposure considerations. VF assessment(VFA) is an efficient, low radiation method for identifying VFs at the time of bone mineral density(BMD) measurement. Prediction models used to indicate the need for VFA may have little predictive power in subspecialty referral populations such as rheumatologic patients or patients who underwent kyphoplasty. Rheumatologic patients are frequently at increased risk for VFs, and VFA should be performed on an individual basis, also taking in account the guidelines for the general population. Kyphoplasty is a new minimal invasive procedure for the treatment of VFs and is being performed with increasing frequency. Following kyphoplasty, there may be a risk of new VFs in adjacent vertebrae. The assessment and follow-up of patients who underwent kyphoplasty requires repetitive X-ray imaging with the known limitations of SR. Thus, VFA may facilitate the evaluation of VFs in these patients because most of the kyphoplasty patients would fulfill the criteria. In a pilot study, we measured the BMD and performed VFA in 28 patients treated with kyphoplasty. Ratios of anterior to posterior(A/P) and middle to posterior(M/P) height were measured, and Genant's method was used to classify vertebrae accordingly. Intraobserver and interobserver reliability for A/P, M/P and the Genant's method were determined. Only 1 patient did not meet the criteria for VFA. Of the 364 available vertebrae, 295 could be analyzed. Most missing data(concerning 69 vertebrae) occurred in the upper thoracic region. Three of the 69 non-eligible vertebrae were lumbar vertebrae with cement leakage from the kyphoplasty procedure. In our hands, VFA was highly reproducible, demonstrating very good agreement in terms of intraobserver and interobserver reliability. Agreement was very good onthe vertebral level, 'vertebrae with kyphoplasty' level and '2 above and 1 below the kyphoplasty vertebrae'level. The application of Genant's method to these patients also resulted in perfect agreement. We believe that the potential value of VFA in patients treated with kyphoplasty requires further evaluation, particularly comparing VFA with SR and performing a longitudinal follow-up. More research will help to adopt care processes that determine which patients require VFA and how often VFA should be performed, while also considering the impact of this technique on the cost of healthcare organizations. | Efstathios Drampalos Konstantinos Nikolopoulos Christos Baltas Alexia Balanika Antonis Galanos Nikolaos Papaioannou Spyros Pneumaticos | 2015 | World Journal of Orthopedics2015,6,9: | 4 |