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| 1 | Genome-editing technologies: the gap between application and policy显示文摘Genome editing is a new technology for manipulating genomic DNA sequences at specific sites,and researchers worldwide are rapidly developing new variants of genomeediting applications that target mRNAs,viruses,chromatin structure,and other cellular processes. | Gousi Li Yao-Guang Liu Yuanling Chen | 2019 | Science China(Life Sciences)2019，62，11： | 9 |
| 2 | Chemical Protein Synthesis by Native Chemical Ligation and Variations Thereof显示文摘For a long time,the total synthesis of proteins was considered as a 'mission impossible' because of the tedious and complex synthetic steps and demanding purification processes.However,with the development of modern synthetic methodologies,many protein syntheses have now been reported.More importantly,through chemical synthesis,desired modifications can be installed to target proteins precisely,which is a major advantage over trad卜tional bio-synthesis approaches.This review summarizes the techniques developed for protein assembly,including native chemical ligation,5e-mediated ligation,and a range of other ligation methods. . | Siyao Wang Yogesh Abaso Thopate Qingqing Zhou Ping Wang | 2019 | Chinese Journal of Chemistry2019，37，11： | 7 |
| 3 | Contemporary processes of environmental information in the atmosphere-glacier-runoff system in an area of typical monsoon temperate glacier显示文摘Sampling was carried out at Baishui No.1, the largest glacier on Mt. Yulong, China, during the summers of 1999 and 2000, to investigate the spatial variations of oxygen isotopes in the atmosphere-glacier-river system. The results confirm that there is an inverse relation between the oxygen isotopic composition of precipitation and air temperature/precipitation amount. This suggests that a strong 'precipitation amount effect' exists in this typical monsoon temperate-glacier region. There are marked differences of the δ18O values of winter-accumulated snow, glacial meltwater, summer precipitation and the glacier-fed river water. Spatial and temporal variations of isotopic composition are controlled by climatic conditions. Isotopic fractionation and differentiation occur during phase changes, snow-to-ice and ice-to-meltwater transformations, and runoff processes. Variations of stable isotopes in glacier runoff can indicate variations of sources of supply, as well as different discharge-related processes. | 何元庆 姚檀栋 张晓君 陈拓 杨梅学 孙维贞 李凤霞 | 2001 | Science China Earth Sciences2001，44，S1： | 6 |
| 4 | Population-size-dependent branching processes in Markovian random environments显示文摘A branching model {Z n} n≥0is considered where the offspring distribution of the population’s evolution is not only dependent on the population size, but also controlled by a Markovian environmental process {ξ n} n≥0. For this model, asymptotic behaviour is studied such as limn→∞Z n and limn→∞Z n/m n in the case that the mean m k, θof the offspring distribution converges to m>1 as the population size k grows to ∞. In the case that {ξ n} n≥0is an irreducible positive recurrent Markov chain, certain extinction (i.e. P(Z n=0 for some n)=1) and noncertain extinction (i.e. P(Z n=0 for some n)<1) are studied. | WANG Hanxing 1 and DAI Yonglong 2 1. Department of Mathematics, Shanghai University, Shanghai 201800, China 2. Department of Mathematics, Zhongshan University, Guangzhou 510275, China | 1998 | Chinese Science Bulletin1998，43，8： | 5 |
| 5 | Standard tri-point transition function显示文摘It is usually difficult to express a family of tri-point transition function (TTF)by a transition matrix as Markov processes with one parameter. In this paper, we define three kinds of connection matrixes on the states of standard tri-point transition function (STTF) and study their essential character, give a constructive method on the constantvalue standard tri-point transition function and a general expression of the state-symmetric standard tri-point transition function by a sequence of the transition matrixes of special and simple Markov processes with one parameter. | XIE Yuquan | 2005 | Science China Mathematics2005，48，7： | 3 |
| 6 | Studies on the interfacial charge transfer processes of nanocrystalline CdSe thin film electrodes by intensity modulated photocurrent spectroscopy显示文摘Interfacial charge transfer kinetics of the nanocrystalline CdSe thin film electrodes have been studied in sodium polysulfide solutions by intensity modulated photocurrent spectroscopy (IMPS). The interfacial direct and indirect charge transfer and recombination processes were analyzed in terms of the parameters: normalized steady state photocurrents and surface state lifetimes obtained by measuring the IMPS responses under different applied potentials and different solution concentrations. IMPS responses of polycrystalline CdSe thin film electrodes were also presented for comparison. | 张敬波 林原 尹峰 肖绪瑞 | 2000 | Science China Chemistry2000，43，4： | 2 |
| 7 | S-Nitrosylation Control of ROS and RNS Homeostasis in Plants: The Switching Function of Catalase显示文摘Nitric oxide(NO),a short-lived gaseous molecule,plays a key role in many physiological and developmental processes.As a lipophilic molecule that can cross all the barriers of biological membranes,NO is able to react with various intracellular/extracellular targets and form a series of reactive nitrogen species(RNS). | Yiqin Wang Chengcai Chu | 2020 | Molecular Plant2020，13，7： | 2 |
| 8 | Frustrated Lewis Pairs:Discovery and Overviews in Catalysis显示文摘Frustrated Lewis Pairs(FLPs)are derived from simple combinations of Lewis acids(electron acceptors)and Lewis bases(electron donors),in which steric demands prevent from forming classical Lewis acid-base adducts.Since 2006,FLP chemistry has emerged as a novel strategy for the design and application of main-group chemistry and development of new metal-free catalytic processes.This strategy has been applied to stoichiometric reactivity and then extended to catalysis.In this review,we briefly summarize the representative discoveries and developments of FLP chemistry in the field of catalysis,including hydrogenation,hydrosilylation,reduction of C 02/transformations of alkynes to organic derivatives,C—H bond borylation and polymerization. | Nan Li Wen-Xiong Zhang | 2020 | Chinese Journal of Chemistry2020，38，11： | 1 |
| 9 | Superprocesses arising from interactive stochastic flows显示文摘In this paper, we give a unified construction for superprocesses with dependent spatial motion constructed by Dawson, Li, Wang and superprocesses of stochastic flows constructed by Ma and Xiang. Furthermore, we also give some examples and rescaled limits of the new class of su perprocesses. | YAN Guojun & LI Zhanbing Medical School, Shantou University, Shantou 515063, China Department of Mathematics, Bejing Normal University, Beijing 100875, China | 2006 | Science China Mathematics2006，49，4： | 1 |
| 10 | STM study on micromorphology of pyrite and dynamic significance of ore-formation显示文摘A careful scanning tunneling microscope (STM) observation has been made on the micromorphology structure of the crystal faces for a group of pyrites which include two types of pyrite specimens: natural pyrites, from the different stage of hydrothermal ore deposits and artificial crystal of pyrite. It has been discovered that there is a set of micromorphological structures on the surfaces of pyrite crystals, including pisolitic hillocks, lotus root-like hillocks and spiral steps. This study reveals that the micromorphology of pyrite crystals, which are closely related to thermodynamic conditions and dynamic environment of the ore-forming systems, carries a lot of genetic information. | Rong Ye Lunshan Zhao Zhesheng Ma Yongli Shen Xiaoping Zhao | 1999 | Chinese Science Bulletin1999，44，15： | 1 |
| 11 | STRONG APPROXIMATIONS FOR THE OPEN QUEUEING NETWORK IN HEAVY TRAFFIC显示文摘In this paper, we prove strong approximations for the open queueing network in heavytraffic. Strong approximations are given for the queueing length, the virtual waiting timeand the sojourn time processes, and for the embedded sequences associated with the queueinglength processes. | 张汉勤 徐光辉 | 1992 | Science China Mathematics1992，35，5： | 1 |
| 12 | Stability of the Soliton Excited in Protein in the Biologic Temperature Range显示文摘The thermal stability of the soliton excited in protein in the biological temperature range of 300-310K have been studied by means of the quantum theory in our theory.The lifetimes of the soliton obtained are in the range of 10^(-9)-10^(-8) s from 300-310K.This result shows that the soliton is very stable in the biologic temperature range and quite useful in biological processes. | PANG Xiaofeng | 1993 | Chinese Physics Letters1993，10，9： | 1 |
| 13 | Binding to m6A RNA promotes YTHDF2-mediated phase separation显示文摘Dear Editor,As one of the most abundant modifications on mRNA in mammal,A^6-methyladenosine(m6A)has been demonstrated to play important roles in various biological processes including nuclear RNA export,mRNA splicing,miRNA processing,mRNA degradation and translation(Shi et al.,2019).Importantly,different m6A reader proteins have been shown to play central roles in these processes. | Jiahua Wang Liyong Wang Jianbo Diao Yujiang Geno Shi Yang Shi Honghui Ma Hongjie Shen | 2020 | Protein & Cell2020，11，4： | 1 |
| 14 | Nearly lattice-defect-free MOF membranes显示文摘Membrane technology has widely accepted as the most energy efficient technology for the separation of ions or molecules. As the core of the membrane technology, the chemical and structure nature of membrane materials determines the application and energy-efficiency of the technology. An advanced membrane that has a remarkable ability to selectively differentiate ions and molecules can significantly enhance the separation technology and revolutionize industrial separation processes. | Yuzhang Zhu Yang Liu Jian Jin | 2024 | Science China Chemistry2024，67，3： | 0 |
| 15 | A Dynamic-Order Fractional Dynamic System显示文摘Motivated by the experimental result of an electronic circuit element'fractor',we introduce the concept of a dynamic-order fractional dynamic system,in which the differential-order of a fractional dynamic system is determined by the output signal of another dynamic system.The concept offers an explanation for the physical mechanism of variable-order fractional dynamic systems and multi-system interaction.The properties and potential applications of dynamic-order fractional dynamic systems are further explored by analyzing anomalous relaxation and diffusion processes. | 孙洪广 盛虎 陈阳泉 陈文 余钟波 | 2013 | Chinese Physics Letters2013，30，4： | 0 |
| 16 | D614G and SARS-CoV-2 replication fitness显示文摘Molecular determinants of SARS-CoV-2 replication fitness and sensitivity to neutralization via the humoral immune response critically inform efforts to combat the COVID-19 pandemic.Work published recently by Plante et al.in Nature highlights a key role for the D614G variant of the viral spike glycoprotein(S protein)in these processes. | Kathleen D.Engelman Alan N.Engelman | 2021 | Signal Transduction and Targeted Therapy2021，6，4： | 0 |
| 17 | Probing New Physics at future electron positron Higgs factories via e^+e^-→ Zγ process显示文摘Direct searches and precision measurements are the two main complementary methods for identifying New Physics at colliders.The next generation of e^+e^-Higgs factories,including CEPC,FCC-ee,ILC and CLIC,is designed to deliver millions of clean Higgs events,together with large samples of other physics processes. | ManQi Ruan | 2021 | Science China(Physics,Mechanics & Astronomy)2021，64，2： | 0 |
| 18 | Sinoviniculture显示文摘In the first instalment of this wine review column,we talked to the winemaker at September Helan in Ningxia.She asserted that being a small scale boutique winery alowed them to,'compar ed with large wineries,have a more precise grasp of[their]vineyards and production processes.' | Joshua Cawthorpe | 2022 | 城市漫步(GBA版)2022，，5： | 0 |
| 19 | The Significance of Physiological Spaces in the Body and Its Medical Implications显示文摘The human body is made up of physical structures and spaces.These physiological spaces play an integral role in metabolic processes.In previous scientific research,these spaces were often neglected.The study of the importance of their existence in the body can help scientifically understand some of the thorniest medical problems that we currently face.It may also help in the diagnosis and prevention of disease,especially of drug-induced origins.The proper reading of the essence of meridians through the perspective of these spaces can help to improve scientific understanding of the principles of acupuncture and moxibustion and the treatment principles of Chinese and Western medicine and ultimately promote the communication and integration of Chinese and Western medicine. | Kezhen Zhang | 2020 | Research2020，，1： | 0 |
| 20 | Meeting the 2020 XPLORER PRIZE Winners (Chemistry and New Materials)显示文摘As one of the major biomacromolecules,glycans mediate various important physiological and pathological processes.On the other hand,gly cans are highly complex and heterogeneous.For studying the biological function of glycosylation in vivo,powerful and straightforward tools re main limited.By developing a series of chemical tools for glycan labeling and analysis at the levels of live cells and living animals,our research focuses on addressing three challenges of the filed:1)cll-selective and tse specific metabolic glycan labeling;2)live-cell labeling and imaging of specific glycoforms for proteins of interest;3)quantitative large-scale profiling of glycoproteins at glycosylation sites. | Editorial Office of Chinese Journal of Chemistry | 2021 | Chinese Journal of Chemistry2021，39，1： | 0 |
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