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| 1 | Nickel-exposed Workers in China: A Cohort Study显示文摘There are more than 50 000 workers in Jinchuan Group Co,Ltd(JNMC).Since all staff in JNMC are eligible for a medical examination every two years,only 23 484 nickel-exposed subjects who participated in medical examination were included in this study.Their data,collected from June 22,2011 to September 28,2012,in a | BAI Ya Na YAGN Ai Min PU Hong Quan HE Jie CHENG Ning ZHENG Tong Zhang DAI Min ZHANG Ya Wei BASSING Bryan WANG Qiu Ying | 2014 | Biomedical and Environmental Sciences2014，27，3： | 20 |
| 2 | Nutrient Intakes of Pregnant Women and their Associated Factors in Eight Cities of China: A Cross-sectional Study显示文摘 | Fang-Li Liu Yu-Mei Zhang Gerard Vinyes Pares Kathleen C Reidy Wen-Zhi Zhao Ai Zhao Cheng Chen Celia Y Ning Ying-Dong Zheng Pei-Yu Wang | 2015 | Chinese Medical Journal2015，，13： | 12 |
| 3 | Methodology and Application for Health Risk Classification of Chemicals in Foods Based on Risk Matrix显示文摘The method has been developed to accurately identify the magnitude of health risks and provide scientific evidence for implementation of risk management in food safety.It combines two parameters including consequence and likelihood of adverse effects based on risk matrix.Score definitions and classification for the consequence and the likelihood of adverse effects are proposed.The risk score identifies the intersection of consequence and likelihood in risk matrix represents its health risk level with different colors:‘low',‘medium',‘high'.Its use in an actual case is shown. | ZHOU Ping Ping LIU Zhao Ping ZHANG Lei LIU Ai Dong SONG Yan YONG Ling LI Ning | 2014 | Biomedical and Environmental Sciences2014，27，11： | 11 |
| 4 | Association of interleukin-6 promoter polymorphism with knee osteoarthritis: a meta-analysis显示文摘 | Ai Zhipeng Ning Xianming Shou Tao Tang Wenru Luo Ying Zhang Jihong | 2014 | Chinese Medical Journal2014，，13： | 10 |
| 5 | Mineral compositions in breast milk of healthy Chinese lactating women in urban areas and its associated factors显示文摘 | Zhao Ai Ning Yibing Zhang Yumei Yang Xiaoguang Wang Junkuan Li Wenjun Wang Peiyu | 2014 | Chinese Medical Journal2014，，14： | 7 |
| 6 | Adsorption of congo red on mesoporous activated carbon prepared by CO2 physical activation显示文摘This research demonstrates the production of mesoporous activated carbon from sargassum fusiforme via physical activation with carbon dioxide.Central composite design was applied to conduct the experiments at different levels by altering three operating parameters.Activation temperature(766-934℃),CO2 flow rate(0.8-2.8 L·min^-1)and activation time(5-55 min)were the variables examined in this study.The effect of parameters on the specific surface area,total pore volume and burn-out rate of activated carbon was studied,and the influential parameters of methylene blue adsorption value were identified employing analysis of variance.The optimum conditions for maximum methylene blue adsorption value were:activation temperature=900℃,activation time=29.05 min and CO2 flow rate=1.8 L·min(-1).The activated carbon produced under optimum conditions was characterized by BET,FTIR and SEM.The adsorption behavior on congo red was studied.The effect of parameters on the adsorbent dosage,temperature,PH and initial congo red concentration was investigated.The adsorption properties of the activated carbon were investigated by kinetics.The equilibrium removal rate and maximum adsorption capacity reaches up to 94.72%,234 mg·g^-1,respectively when initial congo red concentration is 200 mg·L^-1 under adsorbent dosage(0.8 g·L^-1),temperature(30℃),PH7. | Mingjie Ma Huijuan Ying Fangfang Cao Qining Wang Ning Ai | 2020 | Chinese Journal of Chemical Engineering2020，28，4： | 6 |
| 7 | Spatial-temporal variations in near-surface soil freeze-thaw cycles in the source region of the Yellow River during the period 2002–2011 based on the Advanced Microwave Scanning Radiometer for the Earth Observing System(AMSR-E) data显示文摘Detecting near-surface soil freeze-thaw cycles in high-altitude cold regions is important for understanding the Earth's surface system, but such studies are rare. In this study, we detected the spatial-temporal variations in near-surface soil freeze-thaw cycles in the source region of the Yellow River(SRYR) during the period 2002–2011 based on data from the Advanced Microwave Scanning Radiometer for the Earth Observing System(AMSR-E). Moreover, the trends of onset dates and durations of the soil freeze-thaw cycles under different stages were also analyzed. Results showed that the thresholds of daytime and nighttime brightness temperatures of the freeze-thaw algorithm for the SRYR were 257.59 and 261.28 K, respectively. At the spatial scale, the daily frozen surface(DFS) area and the daily surface freeze-thaw cycle surface(DFTS) area decreased by 0.08% and 0.25%, respectively, and the daily thawed surface(DTS) area increased by 0.36%. At the temporal scale, the dates of the onset of thawing and complete thawing advanced by 3.10(±1.4) and 2.46(±1.4) days, respectively; and the dates of the onset of freezing and complete freezing were delayed by 0.9(±1.4) and 1.6(±1.1) days, respectively. The duration of thawing increased by 0.72(±0.21) day/a and the duration of freezing decreased by 0.52(±0.26) day/a. In conclusion, increases in the annual minimum temperature and winter air temperature are the main factors for the advanced thawing and delayed freezing and for the increase in the duration of thawing and the decrease in the duration of freezing in the SRYR. | WANG Rui ZHU Qingke MA Hao AI Ning | 2017 | Journal of Arid Land2017，9，6： | 5 |
| 8 | Serum Gamma-glutamyl Transferase Levels Predict Functional Outcomes after Aneurysmal Subarachnoid Hemorrhage显示文摘Objective We aim to explore the potential association between serum gamma-glutamyl transferase levels and functional outcome after aneurysmal subarachnoid hemorrhage in a Chinese population. Methods A total of 386 aneurysmal subarachnoid hemorrhage patients were included in the study from September 2007 to February 2015. Baseline serum gamma-glutamyl transferase levels and 6-month follow-up functional outcomes were determined. A poor outcome was defined as a modified ranking scale score of ≥ 3. The multivariable logistic model was used to analyze the relationship between serum gamma-glutamyl transferase and clinical outcomes after aneurysmal subarachnoid hemorrhage. Results The adjusted poor outcome rates of patients with gamma-glutamyl transferase levels of < 30 U/L, 30-50 U/L and ≥ 50 U/L were 16.7%, 19.6%, and 34.4%, respectively(P < 0.01). The age-sex and multivariable adjusted odds ratios(95% confidence intervals) of poor prognosis comparing the top group(≥ 50 U/L) with the lowest group(< 30 U/L) were 5.76(2.74-12.13), 6.64(2.05-21.52), and 6.36(1.92-21.02). A significant linear trend existed between gamma-glutamyl transferase level and aneurysmal subarachnoid hemorrhage prognosis. This association was also observed among nondrinkers. Conclusion Patients with higher gamma-glutamyl transferase levels were more likely to have a poor prognosis. Serum gamma-glutamyl transferase can be considered to be an independent predictor of functional outcomes after aneurysmal subarachnoid hemorrhage. | XU Tian WANG Wei ZHAI Lin ZHANG Yun Feng ZHOU Hong Zhi WU Xin Min LI Ai Hong XIE Li Li NING Xiao Jin JI Yu Teng WANG Hong Mei KE Kai Fu | 2017 | Biomedical and Environmental Sciences2017，30，3： | 5 |
| 9 | Night Sleep Duration and Risk of Cognitive Impairment in a Chinese Population: A Cross-sectional Study显示文摘Objective Although sleep is one of the most important health-related behavioral factors,the association between night sleep duration and cognitive impairment has not been fully understood.A cross-sectional study was conducted with a random sample of 2,514 participants(≥40 years of age;46.6% women) in China to examine the association between night sleep duration and cognitive impairment.Methods Night sleep duration was categorized as ≤ 5,6,7,8,or ≥9 h per night.Cognitive function was measured using the Mini-Mental State Examination.A multivariate regression analysis was used to analyze the association of night sleep duration with cognitive impairment.A total of 122 participants were diagnosed with cognitive impairment.Results A U-shaped association between night sleep duration and cognitive impairment was found.The odds ratios(95% confidence intervals) of cognitive impairment(with 7 h of daily sleep being considered as the reference) for individuals reporting ≤ 5,6,8,and ≥9 h were 2.14(1.20-3.83),1.13(0.67-1.89),1.51(0.82-2.79),and 5.37(1.62-17.80),respectively(P≤0.01).Conclusion Short or long night sleep duration was an important sleep-related factor independently associated with cognitive impairment and may be a useful marker for increased risk of cognitive impairment. | SONG Qiao Feng LIU Xiao Xue HU Wan Ning HAN Xiao Chen ZHOU Wen Hua LU Ai Dong WANG Xi Zhu WU Shou Ling | 2017 | Biomedical and Environmental Sciences2017，30，10： | 5 |
| 10 | Prevalence of Metabolic Syndrome in Chinese Nickel-exposed Workers显示文摘The prevalence of metabolic syndrome(MS was investigated in Chinese nickel-exposed workers A total of 35 104 subjects were enrolled in this study.The age-adjusted prevalence of MS,BMI≥25diabetes,hypertension,and abnormal lipid was13.9%,29.5%,12.8%,27.5%,and 47.1%respectively.The prevalence of BMI≥25hyperglycemia,and hypertension increased | YANG Ai Min BAI Ya Na PU Hong Quan ZHENG Tong Zhang CHENG Ning LI Juan Sheng LI Hai Yan ZHANG Ya Wei DING Jiao SU Hui REN Xiao Wei HU Xiao Bin | 2014 | Biomedical and Environmental Sciences2014，27，6： | 5 |
| 11 | Integration of zircon and apatite U–Pb geochronology and geochemical mapping of the Wude basalts(Emeishan large igneous province):A tool for a better understanding of the tectonothermal and geodynamic evolution of the Emeishan LIP显示文摘Radiogenic isotopic dating and Lu–Hf isotopic composition using laser ablation-inductively coupled plasma-mass spectrometry(LA-ICP-MS)of the Wude basalt in Yunnan province from the Emeishan large igneous province(ELIP)yielded timing of formation and post-eruption tectonothermal event.Holistic lithogeochemistry and elements mapping of basaltic rocks were further reevaluated to provide insights into crustal contamination and formation of the ELIP.A zircon U–Pb age of 251.3±2.0 Ma of the Wude basalt recorded the youngest volcanic eruption event and was consistent with the age span of 251-263 Ma for the emplacement of the ELIP.Such zircons hadε_(Hf)(t)values ranging from7.3 to+2.2,identical to those of magmatic zircons from the intrusive rocks of the ELIP,suggesting that crust-mantle interaction occurred during magmatic emplacement,or crust-mantle mixing existed in the deep source region prior to deep melting.The apatite U–Pb age at 53.6±3.4 Ma recorded an early Eocene magmatic superimposition of a regional tectonothermal event,corresponding to the Indian–Eurasian plate collision.Negative Nb,Ta,Ti and P anomalies of the Emeishan basalt may reflect crustal contamination.The uneven Nb/La and Th/Ta values distribution throughout the ELIP supported a mantle plume model origin.Therefore,the ELIP was formed as a result of a mantle plume which was later superimposed by a regional tectonothermal event attributed to the Indian–Eurasian plate collision during early Eocene. | Jia-Nan Fu Franco Pirajno Fan Yang Espine Shivute Yi-Zhan Sun Ning Ai Kun-Feng Qiu | 2021 | Geoscience Frontiers2021，12，2： | 5 |
| 12 | Disaster Risk Science:A Geographical Perspective and a Research Framework显示文摘In this article,we recall the United Nations’30-year journey in disaster risk reduction strategy and framework,review the latest progress and key scientific and technological questions related to the United Nations disaster risk reduction initiatives,and summarize the framework and contents of disaster risk science research.The object of disaster risk science research is the'disaster system'consisting of hazard,the geographical environment,and exposed units,with features of regionality,interconnectedness,coupling,and complexity.Environmental stability,hazard threat,and socioeconomic vulnerability together determine the way that disasters are formed,establish the spatial extent of disaster impact,and generate the scale of losses.In the formation of a disaster,a conducive environment is the prerequisite,a hazard is the necessary condition,and socioeconomic exposure is the sufficient condition.The geographical environment affects local hazard intensity and therefore can change the pattern of loss distribution.Regional multi-hazard,disaster chain,and disaster compound could induce complex impacts,amplifying or attenuating hazard intensity and changing the scope of affected areas.In the light of research progress,particularly in the context of China,we propose a threelayer disaster risk science disciplinary structure,which contains three pillars(disaster science,disaster technology,and disaster governance),nine core areas,and 27 research fields.Based on these elements,we discuss the frontiers in disaster risk science research. | Peijun Shi Tao Ye Ying Wang Tao Zhou Wei Xu Juan Du Jing'ai Wang Ning Li Chongfu Huang Lianyou Liu Bo Chen Yun Su Weihua Fang Ming Wang Xiaobin Hu Jidong Wu Chunyang He Qiang Zhang Qian Ye Carlo Jaeger Norio Okada | 2020 | International Journal of Disaster Risk Science2020，11，4： | 4 |
| 13 | The Pathogenesis and Treatment of COVID-19:A System Review显示文摘INTRODUCTION After the outbreak of severe acute respiratory syndrome(SARS)and Middle East respiratory syndrome(MERS),it was difficult to imagine the recurrence of a virus that can spread worldwide in less than two decades.However,it did.In December of 2019,this virus called severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)was associated with the emergence of pneumonia cases of unknown etiology in Wuhan,Hubei Province. | JI Ye Long WU Yang QIU Zhen MING Hao ZHANG Yi ZHANG Ai Ning LENG Yan XIA Zhong Yuan | 2021 | Biomedical and Environmental Sciences2021，34，1： | 3 |
| 14 | Optimal Waist Circumference Cut-off values for Identifying Metabolic Risk Factors in Middle-aged and Elderly Subjects in Shandong Province of China显示文摘Objective To study the optimal waist circumference(WC) cut-off values for identifying metabolic risk factors in middle-aged and elderly subjects in Shandong Province of China. Methods A total of 2 873 men and 5 559 women were included in this cross-sectional study. Metabolic syndrome(MetS) was diagnosed according to the definition of Chinese Diabetes Society in 2004. The relation between WC and MetS was analyzed by multivariate logistic regression analysis. The optimal WC cut-off values were identified using the area under the ROC curve and the different diagnostic criteria for central obesity were compared. Results The WC was the risk factor for MetS independent of BMI, blood glucose, blood lipid, and blood pressure. The optimal WC cut-off value was 83.8 cm and 91.1 cm for identifying MetS in women and men, respectively. Compared with 80 cm and 85 cm for women and men, 85 cm and 90 cm had a higher Youden index for identifying all metabolic risk factors and MetS in women and men. Conclusion The appropriate WC cut-off value is 85 cm and 90 cm for identifying central obesity and MetS in women and men in Shandong Province of China. | HOU Xin Guo WANG Chuan MA Ze Qiang YANG Wei Fang WANG Ji Xiang LI Cheng Qiao WANG Yu Lian LIU Shu Min Hu Xiu Ping ZHANG Xiu Ping JIANG Mei WANG Wei Qing NING Guang ZHENG Hui Zhen MA Ai Xia SUN Yu SONG Jun LIN Peng LIANG Kai LIU Fu Qiang LI Wen Juan XIAO Juan GONG Lei WANG Mei Jian LIU Ji Dong YAN Fei YANG Jun Peng WANG Ling Shu TIAN Meng ZHAO Ru Xing JIANG Ling CHEN Li | 2014 | Biomedical and Environmental Sciences2014，27，5： | 3 |
| 15 | Trans Fatty Acid Levels in Foods and Intakes among Population Aged 3 Years and above in Beijing and Guangzhou Cities,China显示文摘Objective To understand the dietary intake levels of trans fatty acids(TFA) in a Chinese population and establish a basis for health risk assessment of trans fatty acids. Methods The TFA contents data of 2613 food items and food consumption data of 10,533 people aged 3 years and above in two large cities in China were matched and a simple assessment method was used to estimate the distribution of dietary TFA intake. Results The mean content of TFA was highest in margarine(1.68±0.83 g/100g), followed by chocolate and candy(0.89±2.68 g/100g), edible vegetable oils(0.86±0.82 g/100g), milk(0.83±1.56 g/100g), and bakery foods(0.41±0.91 g/100g). TFA intake accounted for 0.34%, 0.30%, 0.32%, and 0.29% of the total energy intake in the 3-6, 7-12, 13-17, and ≥18 year age groups, respectively. Of the populations studied, 0.42% demonstrated TFA intakes(as percentage of energy intake) greater than 1%. The main sources of dietary TFA intake were edible vegetable oils, milk, mutton, and beef, and baked foods, which accounted for 49.8%, 16.56%, 12.21%, and 8.87%, respectively. Conclusion The current intake of TFA among people in two cities did not appear to be of major health concern regarding the threshold of TFA intake as the percentage of total energy recommended by the World Health Organization. Because most TFA were derived from industrially processed foods, the government should reinforce nutrition labeling and regulate food producers to further reduce TFA in food and to provide scientific instruction for consumers to make sound choices. | LIU Ai Dong LI Jian Wen LIU Zhao Ping ZHOU Ping Ping MAO Wei Feng LI Ning ZHANG Lei | 2015 | Biomedical and Environmental Sciences2015，28，7： | 3 |
| 16 | New Minor Cyclopeptides from Arenaria oreophila (Caryophyllaceae)显示文摘新次要的周期的肽,命名 arenariphilin C 1 和 arenariphilin D 2,从 Arenaria oreophila (石竹科) 的整个植物被孤立。他们的结构我们 redetermined 作为出租机动三轮车(Pro^1-Pro^2-Leu^1-Leu^2-Phe-Ser-Gly-Thr ) 和出租机动三轮车(Ser-Cys ) 根据分光镜的数据,特别由二尺寸的 NMR (2D NMR ) 技术。 | Ai Qun JIA Ning Hua TAN Jun ZHOU | 2006 | Chinese Chemical Letters2006，17，4： | 3 |
| 17 | Infection with severe fever with thrombocytopenia virus in healthy population:a cohort study in a high endemic region,China显示文摘Background: Severe fever with thrombocytopenia (SFTS) caused by SFTS virus (SFTSV) was a tick-borne hemorrhagic fever that posed significant threat to human health in Eastern Asia. The study was designed to measure the seroprevalence of SFTSV antibody in healthy population residing in a high endemic region.Methods: A cohort study was performed on healthy residents in Shangcheng County in Xinyang City from April to December in 2018, where the highest SFTS incidence in China was reported. Anti-SFTSV IgG was measured by indirect enzyme-linked immunosorbent assay and neutralizing antibody (NAb) was detected by using PRNT50. The logistic regression models were performed to analyze the variables that were associated with seropositive rates.Results: Totally 886 individuals were recruited. The baseline seroprevalence that was tested before the epidemic season was 11.9% (70/587) for IgG and 6.8% (40/587) for NAb, which was increased to 13.4% (47/350) and 7.7% (27/350) during the epidemic season, and further to 15.8% (80/508) and 9.8% (50/508) post epidemic. The IgG antibody-based seropositivity was significantly related to the patients aged ≥ 70 years old [adjusted odds ratio (OR) = 2.440, 95% confidence interval (CI): 1.334-4.461 compared to the group of < 50 years old,P = 0.004], recent contact with cats (adjustedOR = 2.195, 95%CI: 1.261-3.818,P = 0.005), and working in tea garden (adjustedOR = 1.698, 95%CI: 1.002-2.880,P = 0.049) by applying multivariate logistic regression model. The NAb based seropositivity was similarly related to the patients aged ≥ 70 years old (adjustedOR = 2.691, 95%CI: 1.271-5.695 compared to the group of < 50 years old,P = 0.010), and recent contact with cats (OR = 2.648, 95%CI: 1.419-4.941,P = 0.002). For a cohort of individuals continually sampled with 1-year apart, the anti-SFTSV IgG were maintained at a stable level, while the NAb level reduced.Conclusions: Subclinical infection might not provide adequate immunity to protect reinfection of SFTSV, thus highlighting the ongoing threats of SFTS in endemic regions, which called for an imperative need for vaccine development. Identification of risk factors might help to target high-risk population for public health education and vaccination in the future. | Xiao‑Lei Ye Ke Dai Qing‑Bin Lu Yan‑Qin Huang Shou‑Ming Lv Pan‑He Zhang Jia‑Chen Li Hai‑Yang Zhang Zhen‑Dong Yang Ning Cui Chun Yuan Kun Liu Xiao‑Ai Zhang Jiu‑Song Zhang Hao Li Yang Yang Li‑Qun Fang Wei Liu | 2021 | Infectious Diseases of Poverty2021，10，6： | 3 |
| 18 | Heavy Metal Assessment among Chinese Nonferrous Metal-exposed Workers from the Jinchang Cohort Study显示文摘Environmental exposure to heavy metals has been linked to a wide range of human health hazards.We detected the levels of 15 metals in urine samples from 500 representative sub-samples in an ongoing occupational cohort study(Jinchang Cohort)to directly evaluate metal exposure levels.Fifteen metals,namely As,Ba,Be,Cd,Cs,Cr,Co,Cu,Pb,Mn,Ni,Se,Tl,U,and Zn,were detected by inductively coupled plasma quadruple mass spectrometry.The results showed that median creatinine adjustment and geometric mean urinary metal levels were higher in the heavy metal-exposed group,except Se and Zn,than other reported general or occupational populations.Further studies should address the effects of heavy metals on human health. | YANG Ai Min CHENG Zhi Yuan PU Hong Quan CHENG Ning LI Hai Yan LIU Si Min DING Jiao LI Juan Sheng HU Xiao Bin REN Xiao Wei ZHENG Tong Zhang BAI Ya Na | 2017 | Biomedical and Environmental Sciences2017，30，7： | 2 |
| 19 | OTFS Enabled NOMA for MMTC Systems over LEO Satellite显示文摘As a complement of terrestrial networks,non-terrestrial networks(NTN)have ad⁃vantages of wide-area coverage and service continuity.The NTN is potential to play an impor⁃tant role in the 5G new radio(NR)and beyond.To enable the massive machine type communi⁃cations(mMTC),the low earth orbit(LEO)satellite is preferred due to its lower transmission delay and path loss.However,the LEO satellite may generate notable Doppler shifts to de⁃grade the system performance.Recently,orthogonal time frequency space(OTFS)modulation has been proposed.It provides the opportunity to allocate delay Doppler(DD)domain resourc⁃es,which is promising for mitigating the effect of high mobility.Besides,as the LEO satellite constellation systems such as Starlink are thriving,the space spectrum resources have become increasingly scarce.Therefore,non-orthogonal multiple access(NOMA)is considered as a candidate technology to realize mMTC with limited spectrum resources.In this paper,the ap⁃plication of OTFS enabled NOMA for mMTC over the LEO satellite is investigated.The LEO satellite based mMTC system and the OTFS-NOMA schemes are described.Subsequently,the challenges of applying OTFS and NOMA into LEO satellite mMTC systems are discussed.Fi⁃nally,the potential technologies for the systems are investigated. | MA Yiyan MA Guoyu WANG Ning ZHONG Zhangdui AI Bo | 2021 | ZTE Communications2021，19，4： | 2 |
| 20 | Risk Assessment of MOAH and MOSH in Infants and Young Children显示文摘Mineral oil hydrocarbons(MOH) in food may come from both contamination and various intentional uses in food production. MOH is widely used in food contact materials and food additives. It comprises complex mixtures, including straight and branched open-chain alkanes(paraffins), largely alkylated cycloalkanes(naphthenes). | ZHU Lei ZHANG Hong CHEN Yan Fen PAN Jing Jing LIU Ai Dong PAN Feng ZHANG Jian Bo ZHONG Huai Ning | 2019 | Biomedical and Environmental Sciences2019，32，2： | 2 |
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