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| 1 | Subclinical abnormal glucose tolerance is a predictor of death in liver cirrhosis显示文摘AIM:To determine if subclinical abnormal glucose tolerance(SAGT)has influence on survival of non-diabetic patients with liver cirrhosis.METHODS:In total,100 patients with compensatedliver cirrhosis and normal fasting plasma glucose were included.Fasting plasma insulin(FPI)levels were measured,and oral glucose tolerance test(OGTT)was performed.According to OGTT results two groups of patients were formed:those with normal glucose tolerance(NGT)and those with SAGT.Patients were followed every three months.The mean follow-up was932 d(range of 180-1925).Survival was analyzed by the Kaplan-Meyer method,and predictive factors of death were analyzed using the Cox proportional hazard regression model.RESULTS:Of the included patients,30 showed NGT and70 SAGT.Groups were significantly different only in age,INR,FPI and HOMA2-IR.Patients with SAGT showed lower 5-year cumulated survival than NGT patients(31.7%vs 71.6%,P=0.02).Differences in survival were significant only after 3 years of follow-up.SAGT,Child-Pugh B,and high Child-Pugh and Model for EndStage Liver Disease(MELD)scores were independent predictors of death.The causes of death in 90.3%of cases were due to complications related to liver disease.CONCLUSION:SAGT was associated with lower survival.SAGT,Child-Pugh B,and high Child-Pugh and MELD scores were independent negative predictors of survival. | Diego García-Compeán Joel Omar Jáquez-Quintana Fernando Javier Lavalle-González José Alberto González-González Linda Elsa Mu?oz-Espinosa Jesús Zacarías Villarreal-PérezEndocrinology Service and Department of Internal Medicine University Hospital 'Dr. José E. González' and Medical School Universidad Autónoma de Nuevo León Monterrey 64320 México Héctor J Maldonado-Garza | 2014 | World Journal of Gastroenterology2014，20，22： | 12 |
| 2 | Physical activity in primary and secondary prevention of cardiovascular disease:Overview updated显示文摘Although the observed progress in the cardiovascular disease treatment, the incidence of new and recurrent coronary artery disease remains elevated and constitutes the leading cause of death in the developed countries. Three-quarters of deaths due to cardiovascular diseases could be prevented with adequate changes in lifestyle, including increased daily physical activity. New evidence confirms that there is an inverse dose-response relationship between physical activity and cardiovascular disease and mortality risk. However, participation in moderate to vigorous physical activity may not fully attenuate the independent effect of sedentary activities on increased risk for cardiovascular diseases. Physical activity also plays an important role in secondary prevention of cardiovascular diseases by reducing the impact of the disease, slowing its progress and preventing recurrence. Nonetheless, most of eligible cardiovascular patients still do not benefit from secondary prevention/cardiac rehabilitation programs. The present review draws attention to the importance of physical activity in the primary and secondary prevention of cardiovascular diseases. It also addresses the mechanisms by which physical activity and regular exercise can improve cardiovascular health and reduce the burden of the disease. | Alberto J Alves Joao L Viana Suiane L Cavalcante Nórton L Oliveira JoséA Duarte Jorge Mota JoséOliveira Fernando Ribeiro | 2016 | World Journal of Cardiology2016，8，10： | 6 |
| 3 | Effects of cellulase and xylanase enzymes mixed with increasing doses of Salix babylonica extract on in vitro rumen gas production kinetics of a mixture of corn silage with concentrate显示文摘An in vitro gas production(GP) technique was used to investigate the effects of combining different doses of Salix babylonica extract(SB) with exogenous fibrolytic enzymes(EZ) based on xylanase(X) and cellulase(C), or their mixture(XC; 1:1 v/v) on in vitro fermentation characteristics of a total mixed ration of corn silage and concentrate mixture(50:50, w/w) as substrate. Four levels of SB(0, 0.6, 1.2 and 1.8 m L g–1 dry matter(DM)) and four supplemental styles of EZ(1 μL g–1 DM; control(no enzymes), X, C and XC(1:1, v/v) were used in a 4×4 factorial arrangement. In vitro GP(m L g–1 DM) were recorded at 2, 4, 6, 8, 10, 12, 24, 36, 48 and 72 h of incubation. After 72 h, the incubation process was stopped and supernatant p H was determined, and then filtered to determine dry matter degradability(DMD). Fermentation parameters, such as the 24 h gas yield(GY24), in vitro organic matter digestibility(OMD), metabolizable energy(ME), short chain fatty acid concentrations(SCFA), and microbial crude protein production(MCP) were also estimated. Results indicated that there was a SB?EZ interaction(P<0.0001) for the asymptotic gas production(b), the rate of gas production(c), GP from 6 to 72 h, GP2(P=0.0095), and GP4(P=0.02). The SB and different combination of enzymes supplementation influenced(P<0.001) in vitro GP parameters after 12 h of incubation; the highest doses of SB(i.e., 1.8 m L g–1 DM), in the absence of any EZ, quadratically increased(P<0.05) the initial delay before GP begins(L) and GP at different incubation times, with lowering b(quadratic effect, P<0.0001) and c(quadratic effect, P<0.0001; linear effect, P=0.0018). The GP was the lowest(P<0.05) when the highest SB level was combined with cellulose. There were SB?EZ interactions(P<0.001) for OMD, ME, the partitioning factor at 72 h of incubation(PF72), GY24, SCFA, MCP(P=0.0143), and p H(P=0.0008). The OMD, ME, GY24 and SCFA with supp lementation of SB extract at 1.8 m L g–1 DM were higher(P<0.001) than the other treatments, however,PF72 was lower(quadratic effect, P=0.0194) than the other levels. Both C and X had no effect(P>0.05) on OMD, p H, ME, GY24, SCFA and MP. The combination of SB with EZ increased(P<0.001) OMD, ME, SCFA, PF72 and GP24, whereas there was no impact on p H. It could be concluded that addition of SB extract, C, and X effectively improved the in vitro rumen fermentation, and the combination of enzyme with SB extract at the level of 1.2 m L g–1 was more effective than the other treatments. | Abdelfattah Z M Salem German Buendía-Rodríguez Mona M M Elghandour María A Mariezcurrena Berasain Francisco J Pea Jiménez Alberto B Pliego Juan C V Chagoyán María A Cerrillo Miguel A Rodríguez | 2015 | Journal of Integrative Agriculture2015，14，1： | 4 |
| 4 | Three-parameter optical fiber sensor based on a tilted fiber bragg grating显示文摘 | Alberto N J Marques C A | 2010 | Applied Optics2010，49，31： | 1 |
| 5 | Pathological changes associated with the 2009 H1N1 virus 显示文摘 | Soto-Abraham MV Soriano-Rosas J Alberto D i az-Qui n a nez | 2009 | N Engl J Med2009，361，20： | 1 |
| 6 | Optimisation of medium composition for clavulanic acid production by Streptomyces clavuligerus显示文摘 | Ester R G Alvaro B N Alberto C B J | 2001 | Biotechnology Letters2001，23，： | 1 |
| 7 | Volatile flavor components of grapefruit juice (citrus paradise macfadyen)显示文摘 | ALBERTO J N HENK M JO M H B | 1985 | J Sci Food Agric1985，36，： | 1 |
| 8 | Optimisation of me- dium composition for clavulanic acid production by Strep- tomyces clavuligerus 显示文摘 | Ester R G Alvaro B N Alberto C B J | 2001 | Biotechnology Letters2001，23，2： | 1 |
| 9 | New copper resistance de- terminants in the extremophile AcidithiobaciUus ferrooxidans : a quantitative proteomic analysis 显示文摘 | Rodrigo J A Claudio A N Alberto P | 2014 | Journal of Proteome Research2014，13，2： | 1 |
| 10 | Optimisation of Medium Composition for Clavulanic Acid Production by Streptomyces Clavuligerus显示文摘 | ESTER R G ALVARO B N ALBERTO C B J | 2001 | Biotechnology Letters2001，23，： | 1 |
| 11 | Behavioral response to selected feed attractants and stimulants in Pacific white shrimp, Litopenaeus vannamei 显示文摘 | ALBERTO J P N MARCELO V C S FRANCISCO F A - N | 2006 | Aquaculture2006，260，： | 1 |
| 12 | Optimisation of medium composition for clavulanic acid production by Streptomyces clavu-ligerus显示文摘 | Ester R G Alvaro B N Alberto C B J | | 0，，： | 1 |
| 13 | Volatile flavour components of grapefruit juice(Citrus paradisi Macfadyen)显示文摘 | ALBERTO J N HENK M JOM H B | 1985 | J Sci Food Agric1985，36，8： | 1 |
| 14 | Recovery of Functional Impairment after Acute Illness and Mortality: One-Year Follow-Up Study显示文摘 | Baztán Juan J Gálvez César P Socorro Alberto | 2009 | Gerontology2009，，3： | 1 |
| 15 | Diversityof endophytic fungal community associated with Piper hispidum(Piperaceae) leaves 显示文摘 | Orlandelli R C Alberto R N Rubin Filho C J | 2012 | Genetics and Molecular Research2012，11，2： | 1 |
| 16 | Diversity of endophyic fungal community associated with Piper hispi alum (Piperaceae) leaves显示文摘 | Orlandelli R C Alberto R N Rubin Filho C J | 2012 | Genetic Molecular Research2012，11，2： | 1 |
| 17 | Oxidation of acylglycerols and phosphoglycerides by soybean lipoxygenase 显示文摘 | George J P Alberto N | 1995 | JAOCS1995，72，： | 1 |
| 18 | Optical Fiber Accderom- eter System for Structural Dynamic Monitoring显示文摘 | Antunes P F D Lima H F T Alberto N J | 2009 | Ieee Sensors lournal2009，9，11： | 1 |
| 19 | Volatile flavor components of grapefruit juice(citrus paradise macfadyen)显示文摘 | ALBERTO J N HENK M JO M H B | 1985 | Sci Food Agric1985，36，： | 1 |
| 20 | Optimization of medium composition for clavulanic acid production by Streptomyces clavuligerus显示文摘 | Ester R G Alvaro B N Alberto C B J | 2001 | Biotechnology Letters2001，23，2： | 1 |
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