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    题名 作者 年代 出处 被引量
1内皮Notch信号的抑制阻碍脂肪酸转运并导致成年心脏的代谢和血管重塑显示文摘营养成分在被肌肉细胞代谢利用之前通过内皮细胞转运。然而,对于内皮运输过程的调节知之甚少。Notch信号传导是发育过程中代谢和血管生成的关键调控因子。在该研究中,Jabs等研究了成年小鼠内皮Notch信号的遗传和药理学调控如何影响内皮脂肪酸转运、心脏血管生成和心脏功能。刘青 叶鹏 Jabs M Rose AJ Lehmann LH Taylor J Moll I Sijmonsma TP Herberich SE Sauer SW Poschet G Federico G Mogler C Weis EM Augustin HG Yan M Gretz N Schmid RM Adams RH Gr9ne HJ Hell R Okun JG Backs J Nawroth PP Herzig S Fischer A 2018中华高血压杂志2018,26,3:6
2Brain changes in diabetes mellitus patients withgastrointestinal symptoms显示文摘Diabetes mellitus is a common disease and its prevalence is increasing worldwide. In various studies up to 30%-70% of patients present dysfunction and complications related to the gut. To date several clinical studies have demonstrated that autonomic nervous system neuropathy and generalized neuropathy of the central nervous system(CNS) may play a major role. This systematic review provides an overview of the neurodegenerative changes that occur as a consequence of diabetes with a focus on the CNS changes and gastrointestinal(GI) dysfunction. Animal models where diabetes was induced experimentally support that the disease induces changes in CNS. Recent investigations with electroencephalography and functional brain imaging in patients with diabetes confirm these structural and functional brain changes. Encephalographic studies demonstrated that altered insular processing of sensory stimuli seems to be a key player in symptom generation. In fact one study indicated that the more GI symptoms the patients experienced, the deeper the insular electrical source was located. The electroencephalography was often used in combination with quantitative sensory testingmainly showing hyposensitivity to stimulation of GI organs. Imaging studies on patients with diabetes and GI symptoms mainly showed microstructural changes,especially in brain areas involved in visceral sensory processing. As the electrophysiological and imaging changes were associated with GI and autonomic symptoms they may represent a future therapeutic target for treating diabetics either pharmacologically or with neuromodulation.Anne M Drewes Eirik Søfteland Georg Dimcevski Adam D Farmer Christina Brock Jens B Frøkjær Klaus Krogh Asbjørn M Drewes 2016World Journal of Diabetes2016,7,2:4
3The Stroke Outcomes and Neuroimaging of Intracranial Atherosclerosis (SONIA) Trial显示文摘E Feldmann J L. Wilterdink A Kosinski M Lynn M I. Chimowitz J Sarafin H H. Smith F Nichols J Rogg H J. Cloft L Wechsler J Saver S R. Levine C Tegeler R Adams M Sloan 2007Neurology2007,,24:2
4Performance of an adaptive multichannel combiner for long range underwater communications显示文摘Sharif B S Neasham J A Hinton O R Adams A E 1996IEE Electronics letters1996,32,3:1
5Isolation of transmissible enteritis agent of turkeys in avian embryos 显示文摘Adams N R Hofstad M S 1971Avian Dis1971,15,:1
6A Computationally Efficient Doppler Compensation Sys tern for Under Water Acoustic Communications显示文摘Sharif B S Neasham J Hinton O R Adams A E 2000IEEE Journal of Oceanic Engineering2000,25,1:1
7Evaluation of hemispherical photography for determining plant area index and geometry of a forest stand显示文摘Chen J M Black T A Adams R S 1991Agricultural and Forest Meteorology1991,56,1:1
8Serelaxin, recombinant human relaxin-2, for treatment of acute heart failure (RELAX-AHF): a randomised, placebo-controlled trial显示文摘John R Teerlink Gad Cotter Beth A Davison G Michael Felker Gerasimos Filippatos Barry H Greenberg Piotr Ponikowski Elaine Unemori Adriaan A Voors Kirkwood F Adams Maria I Dorobantu Liliana R Grinfeld Guillaume Jondeau Alon Marmor Josep Masip Peter S Pang 2013The Lancet . 2013 (9860)2013,,9860:1
9Aeromonas adhesion antigens显示文摘 ADAMS D SAVVAS R S 1987Cellular and Molecular Life Sciences1987,43,4:1
10A novel Pd/MgAlOx catalyst for NOX storage-reduction显示文摘SILLETTI B A ADAMS R T SIGMON S M NIKOLOPOULOS A SPIVEY J J LAMB H H 2006Catal Today2006,114,1:1
11Physical restraint use in inten-sive care units across Europe : the PRICE study 显示文摘Benbenbishty J Adam S Endacott R 2010Intensive andCritical Care Nursing2010,26,5:1
12Use of hydro-jet cutting for lap-aroscopic partial nephrectomyy in a porcine model 显示文摘CORVIN S OBERNEDER R ADAM C 2001Urology2001,58,:1
13Evaluation of hemispherical photography for determining plant area index and geometry of a forest stand显示文摘Chen J M Black T A Adams R S 1991Agricultural and Forest Meteorology1991,56,:1
14Localized infusion of IGF-I resuits in skeletal muscle hypertrophy in rats显示文摘Adams G R McCue S A 1998J Appl Physiol1998,84,5:1
15The ge- nome sequence of Drosophila melanogaster 显示文摘ADAMS M D CELNIKER S E HOLT R A 2000Sci- ence2000,287,5461:1
16Comparative ef-fectiveness of warfarin and new oral anticoagulants for themanagement of atrial fibrillation and venous thromboem-bolism:a systematic review显示文摘Adam S S McDuffie J R Ortel T L 2012Ann Intern Med2012,157,11:1
17Use of preoperative three-dimensional computed tomography to quantify glenoid bone loss in shoulder instability显示文摘Chuang T Y Adams C R Burkhart S S 0,,04:1
18Population comparison of two clinical approaches to the metabolic syndrome implication of the new International Diabetes Federation consensus definition 显示文摘Adams R J Appreton S Wilson DH 2005Diabetes Care2005,28,11:1
19Lack of antioxidant activity of the antiatherogenic compound L-arginine 显示文摘ADAMS M R CO V P ROLAND S 1999Atherosclerosis1999,146,2:1
20Educating effective engineering de- signers: The role of reflective praetice显示文摘Adams R S Tnrns J Atman C J 2003Design Studies2003,24,3:1
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