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| 1 | Pancreatic ductal adenocarcinoma: Risk factors, screening, and early detection显示文摘Pancreatic cancer is the fourth most common cause of cancer-related deaths in the United States, with over 38000 deaths in 2013. The opportunity to detect pancreatic cancer while it is still curable is dependent on our ability to identify and screen high-risk populations before their symptoms arise. Risk factors for developing pancreatic cancer include multiple genetic syndromes as well as modifiable risk factors. Genetic conditions include hereditary breast and ovarian cancer syndrome, Lynch Syndrome, familial adenomatous polyposis, Peutz-Jeghers Syndrome, familial atypical multiple mole melanoma syndrome, hereditary pancreatitis, cystic fibrosis, and ataxia-telangiectasia; having a genetic predisposition can raise the risk of developing pancreatic cancer up to 132-fold over the general population. Modifiable risk factors, which include tobacco exposure, alcohol use, chronic pancreatitis, diet, obesity, diabetes mellitus, as well as certain abdominal surgeries and infections, have also been shown to increase the risk of pancreatic cancer development. Several largevolume centers have initiated such screening protocols, and consensus-based guidelines for screening high-riskgroups have recently been published. The focus of this review will be both the genetic and modifiable risk factors implicated in pancreatic cancer, as well as a review of screening strategies and their diagnostic yields. | Andrew E Becker Yasmin G Hernandez Harold Frucht Aimee L Lucas | 2014 | World Journal of Gastroenterology2014,20,32: | 24 |
| 2 | Expert Assessments of FuturePhotovoltaic Technologies显示文摘 | Curtright Aimee E Morgan M Granger KeithDavid W | 2008 | Policy Analysis2008,42,24: | 1 |
| 3 | The use of the phosphomannose isomerase gene as alternative selectable marker for Agrobacterium-mediated transformation of flax (Linum usitatissimum)显示文摘 | Lamblin F Aime A Hano C Roussy I Domon J M Droogenbroeck B V Laine E | | 0,,26: | 1 |
| 4 | Association between endometriosis and risk of histological subtypes of ovarian cancer: a pooled analysis of case–control studies显示文摘 | Celeste Leigh Pearce Claire Templeman Mary Anne Rossing Alice Lee Aimee M Near Penelope M Webb Christina M Nagle Jennifer A Doherty Kara L Cushing-Haugen Kristine G Wicklund Jenny Chang-Claude Rebecca Hein Galina Lurie Lynne R Wilkens Michael E Carney Mar | 2012 | Lancet Oncology2012,,: | 1 |
| 5 | Frequency dependence of antidepressant response to left prefrontal repetitive transcranial magnetic stimulation (rTMS) as a function of baseline cerebral glucose metabolism显示文摘 | Timothy A Kimbrell John T Little Robert T Dunn Mark A Frye Benjamin D Greenberg Eric M Wassermann Jennifer D Repella Aimee L Danielson Mark W Willis Brenda E Benson Andrew M Speer Elizabeth Osuch Mark S George Robert M Post | 1999 | Biological Psychiatry1999,,12: | 1 |
| 6 | Using High -Probability Foods to Increase the Acceptance of Low -Probability Foods显示文摘 | Meier Aimee E Fryling Mitch J Wallace Michele D | 2012 | Journal of Applied Behavior Analy- sis2012,,45: | 1 |
| 7 | The small-molecule CDK inhibitor,SNS-032,enhances cellular radiosensitivity in quiescent and hypoxic non-small cell lung cancer cells显示文摘 | Elisabeth K Reinhard K Aimee E | 2009 | Lung Cancer2009,66,1: | 1 |
| 8 | Ghrelin ceils replace insulin producing cells in two mouse models of pancreas development 显示文摘 | Catherine L Aimee E Prado | 2004 | PNAS2004,101,9: | 1 |
| 9 | 查看详情显示文摘 | Vega F E Posada F Aime M C | | 0,,: | 1 |
| 10 | The character of power output from utilityscale photovoltaic systems显示文摘 | AIMEE E C JAY A | | 0,,: | 1 |
| 11 | Gastric Bezoar Complicating Laparoscopic Adjustable Gastric Banding, and Review of Literature显示文摘 | Nicole B White MD Karen E Gibbs MD Aimee Goodwin RPA-C Julio Teixeira MD | 2003 | Obesity Surgery2003,,6: | 1 |
| 12 | Upper Thoracic Pedicle Screw Loss of Fixation Causing Spinal Cord Injury:A Review of the Literature and Multicenter Case Series显示文摘 | Kira F Aimee E Charles E | 2013 | J pediatr orthop2013,33,1: | 1 |
| 13 | Ghrelin cells replace insulin-producing cells in twomouse models of pancreas development显示文摘 | Catherine L Aimee E Prado | 2004 | PNAS2004,101,9: | 1 |
| 14 | Neonatal pneumothorax in congenital diaphragmatic hernia:Be wary of high ventilatory pressures显示文摘Background Patients with congenital diaphragmatic hernia(CDH)require invasive respiratory support and higher ventilator pressures may be associated with barotrauma.We sought to evaluate the risk factors associated with pneumothorax in CDH neonates prior to repair.Methods Weretrospectivelyreviewednewborns born withCDHbetween 2014and 2019who developeda pneumothorax,and we matched these cases to patients with CDH without pneumothorax.Results Twenty-sixpatientswere included(n=13per group).The pneumothorax group required extracorporeal life support(ECLS)more frequently(85%vs 54%,p=0.04),particularly among type A/B defects(31%vs 7%,p=0.01).The pneumothorax group had higher positive end-expiratory pressure(PEEP)within 1 hour of birth(p=0.02),at pneumothorax diagnosis(p=0.003),and at ECLS(p=0.02).The pneumothorax group had a higher mean airway pressure(Paw)at birth(p=0.01),within 1 hour of birth(p=0.01),and at pneumothorax diagnosis(p=0.04).Using multiple logistic regression with cluster robust SEs,higher Paw(OR 2.2,95%Cl 1.08 to 3.72,p=0.03)and PEEP(OR 1.8,95%CI 1.15 to 3.14,p=0.007)were associated with an increased risk of developing pneumothorax.There was no difference in survival(p=0.09).Conclusions Development of a pneumothorax in CDH neonates is independently associated with higher Paw and higher PEEP.A pneumothorax increases the likelihood of treated with ECLS,even with smaller defect. | Nathan Rubalcava Gabriella A Norwitz Aimee G Kim Gary Weiner Niki Matusko Meghan A Arnold George B Mychaliska Erin E Perrone | 2022 | World Journal of Pediatric Surgery2022,5,3: | 0 |