维普中文期刊产品整合服务
18篇 您的检索式:作者名="Aluned A A"
    题名 作者 年代 出处 被引量
1Calcium signaling and T-type calcium channels in cancer cell cycling显示文摘Regulation of intracellular calcium is an important signaling mechanism for cell proliferation in both normal and cancerous cells. In normal epithelial cells, free calcium concentration is essential for cells to enter and accomplish the S phase and the M phase of the cell cycle. In contrast, cancerous cells can pass these phases of the cell cycle with much lower cytoplasmic free calcium concentrations, indicating an alternative mechanism has developed for fulfilling the intracellular calcium requirement for an increased rate of DNA synthesis and mitosis of fast replicating cancerous cells. The detailed mechanism underlying the altered calcium loading pathway remains unclear; however, there is a growing body of evidence that suggests the T-type Ca2+ channel is abnormally expressed in cancerous cells and that blockade of these channels may reduce cell proliferation in addition to inducing apoptosis. Recent studies also show that the expression of T-type Ca2+ channels in breast cancer cells is proliferation state dependent, i.e. the channels are expressed at higher levels during the fast-replication period, and once the cells are in a non-proliferation state, expression of this channel isminimal. Therefore, selectively blocking calcium entry into cancerous cells may be a valuable approach for preventing tumor growth. Since T-type Ca2+ channels are not expressed in epithelial cells, selective T-type Ca2+ channel blockers may be useful in the treatment of certain types of cancers.James T Taylor Xiang-Bin Zeng Jonathan E Pottle Kevin Lee Alun R Wang Stephenie G Yi lennifer A S Scruggs Suresh S Sikka Ming Li 2008World Journal of Gastroenterology2008,14,32:12
2A homogenous linear programming algorithm for the security constrained economic dispatch problem显示文摘RABIN A J ALUN H C BRIAN J C 2000IEEE Transactions on Power Systems2000,15,3:1
3Large-scale dispersant leaching and effectiveness ex- periments with oils on calm water 显示文摘Alun Lewis A B Ken Trudel Randy C Belore 2010Marine Pollution Bulletin2010,60,2:1
4A homogenous linear programming algorithm for the security constrained economicdispatch problem显示文摘Rabin A Jabr Alun H Coonick Brian J Cory 2000IEEE Trans on PS2000,15,3:1
5Role of soft pH in the development of enhanced biodegradation of fenamiphos显示文摘 Walker S A Alun J 2003Applied and Environmental Microbiology2003,19,:1
6Circulating soluble adhesion molecules ICAM-1 and VCAM-1 and incident coronary heart disease: the PRIME study显示文摘GERALD LUC A B DOMINIQUE ARVEIER C ALUN EVANS D 2003Atherosclerosis2003,170,1:1
7A homogenous linear programming algorithm for the security constrained economic dispatch problem 显示文摘Rabin A Jabr Alun H Coonick Brian J Cory 2000IEEE Trans on PS2000,15,3:1
8A homogenous linear programming algorithm for the security constrained economic dispatch problem显示文摘Rabin A Jabr Alun H Coonick Brian J Cory 2000IEEE Transactions on Power Systems2000,15,3:1
9Local Stability Analysis of Spatially Homogeneous显示文摘Vincent A A Jansen Alun L Lloyd 2000Journal Mathematical Biology2000,,41:1
10Circulating soluble adhesion molecules ICAM-1 and VCAM-1 and incient coronary heart disease:the PRIME study显示文摘Gerald LUC A B Dominique Arveier C Alun Evans D 2003Atherosclerosis2003,170,1:1
11A homogeneous linear programming algorithm for the security constrained economic dispatch problem显示文摘Rabih A J Alun H C Brian J C 2000IEEE Trans on Power Systems2000,15,3:1
12Hydroxyproline Quantification for the Estimation of Collagen in Tissue Using Multiple Reaction Monitoring Mass Spectrometry 显示文摘MICHELLE L C PETER G A ALUN J 2008Journal of Chromatography A2008,1212,:1
13Protective effect of red grape seeds proanthocyanidins against induction of diabetes by alloxan in rats 显示文摘Ei-Afly A T Aluned A A Fatani A J 2005Pharmacol Res2005,52,3:1
14Across the divide: reconciling farm and town views of agriculture-community linkages 显示文摘John S Alun E J Matthew A 2005Journal of Rural Studies2005,21,:1
15Jones Effects of Resistance Exercise Volume and Nutritional Supplementation on Anabolic and Catabolic Hormones 显示文摘ALUN G WILLIAMS A Naim Ismail Anita Sharma David A 2002Eur J Appl Physiol2002,,86:1
16Sensitive specific quantitative analysis of tacrolimus(FK506)in blood by liquid chromatography-electrospray tandem mass spectrometry显示文摘Taylor J Alun J Glenda A 1996Clin Chem1996,42,2:1
17Innate immunity and monocyte-macrophage activation in atherosclerosis显示文摘Joseph Shalhoub Mika A Falck-Hansen Alun H Davies 2011Journal of Inflammation2011,8,9:1
18Stability of aqueous α-Al2O3 suspensions withpoly(methacrylic acid) polyelectrolyte 显示文摘JOSEPH C ILHAN A A ALUN B 1988Am Ceram Soc1988,71,4:1
返回顶部 每页显示:
共1页 首页 上一页 第1页 下一页 末页 /1 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费