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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Body composi-tion and net requirements of protein and energy for weight gain of nellore and crossbreed steers finished under grazing显示文摘 | Sant'Ana N F Fontes C A A Silva R S T | | 0，，04： | 1 |
| 3 | Nile Tilapia ( Oreochromis niloticus), Liver Morphology, CYP1A Activity and Thyroid Hormones After Endosulfan Dietary Exposure 显示文摘 | ANA M C ANTONIO F F MARIA A R | 2007 | Pesticide Biochemistry and Physiology2007，89，3： | 1 |
| 4 | Segmenting wine consumers according to their involvement with appellations of origin 显示文摘 | Carmen R S Miguel C B Ana G F | 2006 | Journal of Brand Management2006，13，45： | 1 |
| 5 | Arabidopsis and tobacco plants ectopically expressing the soybean antiquitin-like ALDH7 gene display enhanced tolerance to drought,salinity,and oxidative stress显示文摘 | Simone M R Maxuel O A Ana P S G Fabio M D Maria C B P Elizabeth P B F | | 0，，： | 1 |
| 6 | Effects of soybean Kunitz trypsin inhibitor on the cotton boll weevil (Anthonomus grandis)显示文摘 | FRANCOA O L DIASB S C MAGALHA_ESD C P MONTEIROA ANA C S JR C B MELOE F R OLIVEIRA-NETOA O B MONNERATA R G GROSSI-DE-SA M F | 2004 | Phytochernistry2004，65，1： | 1 |
| 7 | Application of PCR ribotyping and tDNA-PCR for Klebsiella pneumoniae identification显示文摘 | Ana Catarina S L Juliana F R Maysa B M C | 2007 | Mere Inst Oswaldo Cruz Rio de Janeiro2007，102，7： | 1 |
| 8 | Studies on the interaction of emeraldine base polyaniline with Cu(Ⅱ), Fe(Ⅲ), and Zn(Ⅱ) ions in solutions and films显示文摘 | Celly M S I Ana M D C F Vera R L C | 2007 | Macromolecules2007，40，： | 1 |
| 9 | The influence of activated carbon surface properties on the adsorption of the herbicide molinate and the bio-regeneration of t he adsor- bent显示文摘 | C1 fi udia C Ana S O Manuel F R | 2006 | Journal of Hazardous Materials B2006，138，： | 1 |
| 10 | A 2S albumin-homologous protein from passion fruit seeds inhibits the fungal growth and acidification of the medium by Fusarium oxysporum 显示文摘 | Ana P A Andr60 C Suzanna de Fitima F R | 2003 | Archives of Biochemistry and Biophysics2003，416，2： | 1 |
| 11 | Bamboo overabundance alters forest structure and dynamics in the Atlantic Forest hotsoot 显示文摘 | Lima R A F Rother D C Ana E M | 2012 | Biological Conservation2012，147，1： | 1 |
| 12 | Frequencies of GSTM1, GSTT1, and GSTP 1 polymorphisms in a Brazilian population显示文摘 | Ana Rossinil Davy C M Rapozol Lidia M F Amorim2 Jacyara M B Macedo1 Raquel Medina1 Jose F N Neto3 Claudia V M Gallol and Luis F R Pintol | 2002 | Genetics and Molecular Research2002，1，3： | 1 |
| 13 | Design and sensitivity analysis using the probability-safetyfactor method: an application to retaining walls显示文摘 | ENRQUE C ROBERTO M ANA R T ALFONSO F C | 2004 | Structural Safety2004，26，2： | 1 |
| 14 | Design and sensitivity analysis using the probability- safety-factor method:an application to retaining walls显示文摘 | ENRQUE C ROBERTO M ANA R T ALFONSO F C | 2004 | Stmctural Safety2004，26，2： | 1 |
| 15 | Immunohistochemical expression of estrogen and progesterone receptors in endometrial polyps and adjacent endometrium in postmenopausal women显示文摘 | Sant'Ana de A E C Nogueira A A Candido dos R F J | 2004 | Maturitas2004，49，3： | 1 |
| 16 | Diffusion coeffi- cients in aqueous solutions of potassium chloride at high and low concentrations 显示文摘 | Victor M M L Ana C F R Luis M P V | 1998 | Journal of Molecular Liquids1998，78，： | 1 |
| 17 | Effect of enzymatic hy- drolysis on some physicochemical properties of root and tuber granular starches显示文摘 | Thais de S R Ana P A C Celia M L F | 2010 | Cienc Tecnol Aliment Campinas2010，30，2： | 1 |
| 18 | Solid-state characterization and dissolution profiles of the inclusion complexes of omeprazole with native and chemically modified β-cyclodextrin显示文摘 | Ana F Rui A C Laura R | 2007 | European Journal of Pharmaceutics and Biopharmaceutics2007，67，： | 1 |
| 19 | Health and environmental assessment of mercury exposure in a gold mining community in western Mindanao, Philippines显示文摘 | NELIA C M JOSE P R ANA T F R | 2006 | Journal of Environmental Management2006，81，2： | 1 |
| 20 | 饲喂有机硒对哺乳犊牛生产性能和免疫反应的影响显示文摘研究旨在探讨在哺乳犊牛饲料中添加不同水平的硒,直接作用于皱胃时犊牛免疫系统的增强和生长性能的提高是否优于瘤胃。选用75日龄的新生犊牛(荷斯坦×新泽西州)30头,随机分配成3组:C组为对照组(不补充硒,硒源只来源于牛奶中);Se A组为皱胃0.80 mg·头-1·d-(1注射);Se R组为瘤胃0.80 mg·头-1·d-(1口服)。犊牛在30日龄时,两个试验组犊牛血液中硒的浓度极显著高于对照组(P=0.001)。两个试验组犊牛的巨噬细胞的吞噬活性高于对照组,其中Se A组极显著高于Se R组(P=0.007)。在犊牛30日龄期间,各组间犊牛的中性粒细胞和血细胞比容的氧化活性无显著差异。30日龄Se R组的哺乳犊牛的干物质采食量(P=0.059)和胸围增益(P=0.059)均显著高于Se A组(P<0.01)。与对照组相比,补充硒可有效提高犊牛的饲料转化率(P=0.075)。30日龄各组犊牛的体增重(P=0.059)、高度和长度均无显著差异。在75日龄时,补充硒的犊牛的血液中硒含量(P=0.079)和胸围(P=0.088)呈现增加的趋势。在哺乳犊牛的牛奶中补充有机硒0.80 mg可增加血清中硒含量,并增强其30日龄时的免疫机能。对犊牛皱胃补充硒其免疫反应优于对犊牛瘤胃的补充。此外,补充硒可减少对动物生产中腹泻。补硒不能哺乳犊牛生长,但可以提高哺乳期间的免疫功能。 | Márcia S V S Marcus A Z Luiz C R J Fernando A S Ana EC S Az Elyara M S Lúcia H F Yara M L V | 2014 | 饲料博览2014，0，11： | 0 |
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