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| 1 | 皮质下小血管病诊断的共识声明显示文摘血管性认知损害是用于描述一组涉及大血管和小血管的散发性和遗传性异质性疾病的诊断术语。皮质下小血管病可导致腔隙性梗死和进行性白质损害。被称为宾斯旺格病(Binswanger's disease, BD)的进行性白质损害患者构成了从单纯血管性疾病到合并神经变性病变的疾病谱。BD患者是一个相对同质性的亚组,存在缺氧缺血、腔隙性梗死和炎症,它们协同作用破坏血脑屏障和髓鞘。通过临床、脑脊液、神经心理学和影像学检查获得的多模式疾病标记物能促进该亚组患者的鉴别。本共识声明确定了一系列基于基础病理学改变的潜在生物学标记物,这将有助于诊断以及将来协作性治疗试验的患者选择。 | Gary A Rosenberg Anders Wallin Joanna M Wardlaw Hugh S Markus Joan Montaner Leslie Wolfson Costantino Iadecola Berislav V Zlokovic Anne Joutel Martin Dichgans Marco Duering Reinhold Schmidt Amos D Korczyn Lea T Grinberg Helena C Chui Vladimir Hachinski 王训师 张劼 陈涵丰 俞娅美 徐子奇 罗本燕 | 2016 | 国际脑血管病杂志2016,24,6: | 18 |
| 2 | Gastroenteropancreatic neuroendocrine tumours显示文摘 | Irvin M Modlin Kjell Oberg Daniel C Chung Robert T Jensen Wouter W de Herder Rajesh V Thakker Martyn Caplin Gianfranco Delle Fave Greg A Kaltsas Eric P Krenning Steven F Moss Ola Nilsson Guido Rindi Ramon Salazar Philippe Ruszniewski Anders Sundin | 2008 | Lancet Oncology2008,,1: | 8 |
| 3 | 【特刊综述】性腺功能低下在克氏综合征中的角色显示文摘克氏综合症(47,XXY)(KS)是最常见的性染色体异常,也是男性不育和性腺功能低下的常见原因。大部分KS患者终其一生都不知道自己患有这个疾病,只有25%的患者得到诊断,而在青春期前被诊断的更是少数。除了性腺功能低下和无精子症,大多数KS患者都有一定程度的学习障碍,并且可能有多种精神问题。长期性腺功能低下的影响可能使其难以与额外的x染色体引起的基因剂量效应相辨别。不管是什么原因,KS患者常出现身体成分的改变,包括脂肪增加、肌肉减少和骨矿物质流失,同时发生代谢障碍的风险也增加,例如患2型糖尿病和代谢综合征。这些发现应该引起我们的重视,因为他们不仅仅是简单的化验结果,流行病学调查表明KS患者因不同的疾病住院和死亡的风险均增加。KS患者应该在青春期早期就被给予睾丸激素治疗,尽管目前证据不足,因为至今仍未有随机对照试验的文章发表过。在这篇文章里,我们回顾了近期关于KS患者性腺功能低下症的研究进展和睾丸激素治疗的合理性,希望能为这个常见但往往被忽视的综合征提出我们的最佳建议。 | Christian Host Anne Skakkeb k Kristian A Groth Anders Bojesen | 2014 | Asian Journal of Andrology2014,16,2: | 3 |
| 4 | On the macroparticle flux from vacuum arc cathode spots显示文摘 | Anders S Anders A Kin M Y | 1993 | IEEE Trans On Plasma Science1993,21,: | 2 |
| 5 | Prospective evaluation of the short access cholangioscopy for stone clearance and evaluation of indeterminate strictures显示文摘BACKGROUND: Peroral cholangioscopy facilitates diagnosis and therapy of biliary disorders. This study prospectively evaluated a new short access cholangioscopy. METHODS: Consecutive patients were included as follows: difficult stones(group 1) underwent cholangioscopy with electrohydraulic lithotripsy and indeterminate biliary strictures(group 2) were evaluated with macroscopic assessment and cholangioscopy guided biopsy sampling. We evaluated the complete stone clearance rate(group 1) and diagnostic accuracy(group 2). Follow-up was performed over a median of 13 and 16 months, respectively.RESULTS: Group 1(n=21): complete stone clearance defined as lack of stones in cholangiography and stone removal during cholangioscopy was achieved in 15(71.4%) patients. Clinical stone clearance defined as lack of symptoms, laboratory abnormalities and hospital visits during follow-up, irrespective of stone clearance was evident in 17(81.0%) patients. One serious adverse event occurred(bile duct perforation). Group 2(n=28): malignancy was confirmed in 15 patients. Sensitivity, specificity and diagnostic accuracy of cholangioscopy were 85.7%, 75.0% and 80.7%, respectively. Sensitivity, specificity and diagnostic accuracy of biopsies were 54.5%, 100.0% and 72.2%, respectively. No serious adverse events occurred, and one patient was lost to follow-up.CONCLUSIONS: The novel system enabled complex stone treatment and biliary stricture diagnosis. Cholangioscopy outperformed direct biopsy regarding characterization of indeterminate strictures. | Athanasios D Sioulas Muhammad A El-Masry Stefan Groth Guido Schachschal Mario Anders Thomas Rosch Ulrike Denzer | 2017 | Hepatobiliary & Pancreatic Diseases International2017,16,1: | 2 |
| 6 | A 4GHz 300mW 64b integer execution ALU with dual supply voltages in 90nm C MOS 显示文摘 | Mathew S K Anders M A Bloechel B etal | 2005 | IEEE Journal of Solid - State Circuits2005,40,1: | 1 |
| 7 | Mechanisms of bed agglomeration during fluidized-bed combustion of biomass fuels 显示文摘 | Elisabet B Marcus O Anders A | 2005 | Energy & Fuels2005,19,3: | 1 |
| 8 | Measurement and evaluation of moisture transport coefficients during drying of wood 显示文摘 | ANDERS R JESPER A | 1997 | Holzforschung1997,51,: | 1 |
| 9 | Extremely low-frequency magnetic fields and heart disease显示文摘 | Leeka K Anders A Christoffer J | 2007 | Scand J Work Environ Health2007,33,1: | 1 |
| 10 | Laboratory testing of a new type of energy absorbing rock bolt显示文摘 | ANDERS A | 2005 | Tunnelling and Underground Space Technology2005,20,: | 1 |
| 11 | Drag coefficients of single droplets moving in an infinite droplet chain on the axis of a tube显示文摘 | Anders K Frohn A | 1988 | Int J of Multiphase Flow1988,,4: | 1 |
| 12 | Staphylococcus saprophyticus ATCC 15305 is internalized into human urinary bladder carcinoma cell line 5637显示文摘 | Szabados F Kleine B Anders A | 2008 | FEMS Microbiol Lett2008,285,2: | 1 |
| 13 | Pyrolysis of iron and cobalt porphyrin sublimated onto the surface of carbon black显示文摘 | Anders A | 1996 | Electrochimica Acta1996,41,10: | 1 |
| 14 | On the robust estimation of power spectra, coherences, and transfer functions显示文摘 | Chave A D Thomson D J Ander M E | 1987 | Journal of Geophysical Research1987,92,1: | 1 |
| 15 | Improving software quality in safety-critical applications by model-driven verification显示文摘 | Anders Henriksson Uwe A man James Hunt | | 0,,31: | 1 |
| 16 | Dynamic testing of steel for a new type of energy absorbing rock bolt显示文摘 | ANDERS A | 2006 | Journal of Constructional Steel Research2006,62,: | 1 |
| 17 | Generator maintenance scheduling to maximize reliability and revenue 显示文摘 | Silva A M L Anders G J Manso L A F | 2001 | Power Tech Proceedings2001,4,10: | 1 |
| 18 | Propane dehydrogenation over supported Pt and Pt-Sn catalysts: cat- alyst preparation, characterization, and activity measurement 显示文摘 | Odd A Barias Anders Holmen Edd A Blekkann | 1996 | Journal of Catalysis1996,158,: | 1 |
| 19 | Impaired glucose tolerance associated with adverse pregnancy outcomes: A population-based study in southern Sweden显示文摘 | Aberg A Rydhstroem H Frid Anders | 2001 | Am J Obstet& Gynecol2001,184,: | 1 |
| 20 | Reducing ion-beam noise of vacuum arc ion sources显示文摘 | Anders A Hollinger R | 2002 | Rev Sci Instrum2002,73,2: | 1 |