|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Nephrotoxicity in cancer treatment:An overview显示文摘Anticancer drug nephrotoxicity is an important and increasing adverse drug event that limits the efficacy of cancer treatment.The kidney is an important elimination pathway for many antineoplastic drugs and their metabolites,which occurs by glomerular filtration and tubular secretion.Chemotherapeutic agents,both conventional cytotoxic agents and molecularly targeted agents,can affect any segment of the nephron including its microvasculature,leading to many clinical manifestations such as proteinuria,hypertension,electrolyte disturbances,glomerulopathy,acute and chronic interstitial nephritis,acute kidney injury and at times chronic kidney disease.The clinician should be alert to recognize several factors that may maximize renal dysfunction and contribute to the increased incidence of nephrotoxicity associated with these drugs,such as intravascular volume depletion,the associated use of nonchemotherapeutic nephrotoxic drugs(analgesics,antibiotics,proton pump inhibitors,and bonetargeted therapies),radiographic ionic contrast media or radiation therapy,urinary tract obstruction,and intrinsic renal disease.Identification of patients at higher risk for nephrotoxicity may allow the prevention or at least reduction in the development and severity of this adverse effect.Therefore,the aim of this brief review is to provide currently available evidences on oncologic drug-related nephrotoxicity. | Maria Luísa Cordeiro Santos Breno Bittencourt de Brito Filipe Antonio FranÇa da Silva Anelise Costa dos Santos Botelho Fabrício Freire de Melo | 2020 | World Journal of Clinical Oncology2020，11，4： | 4 |
| 2 | Effects of living and metabolically inactive mesenchymal stromal cells and their derivatives on monocytes and macrophages显示文摘Mesenchymal stromal cells (MSCs) are multipotent and self-renewing stem cellsthat have great potential as cell therapy for autoimmune and inflammatorydisorders, as well as for other clinical conditions, due to their immunoregulatoryand regenerative properties. MSCs modulate the inflammatory milieu by releasingsoluble factors and acting through cell-to-cell mechanisms. MSCs switch theclassical inflammatory status of monocytes and macrophages towards a nonclassicaland anti-inflammatory phenotype. This is characterized by an increasedsecretion of anti-inflammatory cytokines, a decreased release of pro-inflammatorycytokines, and changes in the expression of cell membrane molecules and inmetabolic pathways. The MSC modulation of monocyte and macrophage phenotypesseems to be critical for therapy effectiveness in several disease models, sincewhen these cells are depleted, no immunoregulatory effects are observed. Here,we review the effects of living MSCs (metabolically active cells) and metabolicallyinactive MSCs (dead cells that lost metabolic activity by induced inactivation) andtheir derivatives (extracellular vesicles, soluble factors, extracts, and microparticles)on the profile of macrophages and monocytes and the implications forimmunoregulatory and reparative processes. This review includes mechanisms ofaction exhibited in these different therapeutic appro-aches, which induce the antiinflammatoryproperties of monocytes and macrophages. Finally, we overviewseveral possibilities of therapeutic applications of these cells and their derivatives,with results regarding monocytes and macrophages in animal model studies andsome clinical trials. | Alexia Nedel Sant'Ana Anelise Bergmann Araújo Fabiany da Costa Gonçalves Ana Helena Paz | 2021 | World Journal of Stem Cells2021，13，9： | 2 |
| 3 | Genetic and phenotypic diversity of plant-growth-promoting bacilli isolated from wheat fields in southern Brazil显示文摘 | Anelise Beneduzi Daiane Peres Pedro Beschoren da Costa Maria Helena Bodanese Zanettini Luciane Maria Pereira Passaglia | 2008 | Research in Microbiology2008，，4： | 1 |
| 4 | Rapid and sensitive anthrone–sulfuric acid assay in microplate format to quantify carbohydrate in biopharmaceutical products: Method development and validation显示文摘 | Alberto Leyva Anelis Quintana Meily Sánchez Elias N. Rodríguez José Cremata Julio C. Sánchez | 2007 | Biologicals2007，，： | 1 |
| 5 | Semiconductive properties of titanium anodic oxide films in McIlvaine buffer solution 显示文摘 | Anelise M Denise S Emilse M | 2006 | Corrosion Science2006，48，： | 1 |
| 6 | Natural goethite reduced with dithionite: Evaluation of the reduction process by XANES and Mosshauer spectroscopy and application of the catalyst in the oxidation of model organic compounds 显示文摘 | ANELISE de ABREU L IARA GUIMARAES R | 2012 | J Mol Catal A: Chem2012，356，： | 1 |
| 7 | CYP1A1,CYP2E1 and EPHX1 polymorphisms in sporadic colorectal neoplasms显示文摘AIM To investigate the contribution of polymorphisms in the CYP1A1, CYP2E1 and EPHX1 genes on sporadic colorectal cancer(SCRC) risk. METHODS Six hundred forty-one individuals(227 patients with SCRC and 400 controls) were enrolled in the study. The variables analyzed were age, gender, tobacco and alcohol consumption, and clinical and histopathological tumor parameters. The CYP1A1 *2A, CYP1A1 *2C CYP2E1 *5B and CYP2E1 *6 polymorphisms were analyzed by polymerase chain reaction-restriction fragment length polymorphism(PCR-RFLP). The EPHX1 Tyr113 His, EPHX1 His139 Arg and CYP1A1 *2C polymorphisms were detected by real-time PCR. Chisquared test and binary logistic regression were used in the statistical analysis. Haplotype analysis was conducted using the Haploview program, version 2.05.RESULTS Age over 6 2 years was a risk factor for SCRC development(OR = 7.54, 95%CI: 4.94-11.50, P < 0.01). Male individuals were less susceptible to SCRC(OR = 0.55, 95%CI: 0.35-0.85, P < 0.01). The CYP2E1*5B polymorphism was associated with SCRC in the codominant(heterozygous genotype: OR = 2.66, 95%CI: 1.64-4.32, P < 0.01), dominant(OR = 2.82, 95%CI: 1.74-4.55, P < 0.01), overdominant(OR = 2.58, 95%CI: 1.59-4.19, P < 0.01), and log-additive models(OR = 2.84, 95%CI: 1.78-4.52, P < 0.01). The CYP2E1*6 polymorphism was associated with an increased SCRC risk in codominant(heterozygous genotype: OR = 2.81, 95%CI: 1.84-4.28, P < 0.01; homozygous polymorphic : OR = 7. 3 2, 9 5 % C I : 1.85-28.96, P < 0.01), dominant(OR = 2.97, 95%CI: 1.97-4.50, P < 0.01), recessive(OR = 5.26, 95%CI: 1.35-20.50, P = 0.016), overdominant(OR = 2.64, 95%CI: 1.74-4.01, P < 0.01), and log-additive models(OR = 2.78, 95%CI: 1.91-4.06, P < 0.01). The haplotype formed by the minor alleles of the CYP2E1*5B(C) and CYP2E1*6(A) polymorphisms was associated with SCRC(P = 0.002). However, the CYP1A1 *2A, CYP1A1 *2C, EPHX1 Tyr113 His and EPHX1 His139 Arg polymorphisms were not associated with SCRC.CONCLUSION In conclusion, the results demonstrated that CYP2E1*5B and CYP2E1*6 minor alleles play a role in the development of SCRC. | Glaucia Maria M Fernandes Anelise Russo Marcela Alcantara Proenca Nathalia Fernanda Gazola Gabriela Helena Rodrigues Patrícia Matos Biselli-Chicote Ana Elizabete Silva Joao Gomes Netinho érika Cristina Pavarino Eny Maria Goloni-Bertollo | 2016 | World Journal of Gastroenterology2016，22，45： | 1 |
| 8 | Semiconductive Properties of Titanium Anodic Oxide Films in McIlvaine Buffer Solution 显示文摘 | Anelise M S Denise S A Emilse M A M | 2006 | Corrosion Science2006，48，10： | 1 |
| 9 | Evaluation of genetic diversity and plant growth promoting activities of nitrogen-fixing bacilli isolated from rice fields in South Brazil显示文摘 | Anelise Beneduzi Daiane Peres Luciano K. Vargas Maria Helena Bodanese-Zanettini Luciane Maria P. Passaglia | 2008 | Applied Soil Ecology2008，，3： | 1 |
| 10 | Some aspects of acylation of cellulose under homogeneous solution conditions显示文摘 | Regiani Anelise M Frollini Elisabete Marson Guilherme A | 1999 | J Polym Sci Part A: Polym Chem1999，37，： | 1 |
| 11 | Molecular evaluation of glutathione S transferase family genes in patients with sporadic colorectal cancer显示文摘AIM To evaluate the association between polymorphismsin glutathione S transferases(GSTs) and the risk of sporadic colorectal cancer(SCRC), tumor progression and the survival of patients.METHODS A case-control study of 970 individuals from the Brazilian population was conducted(232 individuals from the case group with colorectal cancer and 738 individuals from the control group without a history of cancer). PCR multiplex and PCR-RFLP techniques were used to genotype the GST polymorphisms. The tumors were categorized according to the TNM classification: tumor extension(T), affected lymph nodes(N), and presence of metastasis(M). Logistic regression, multiple logistic regression and survival analysis were used to analyze the data. The results are presented in terms of odds ratio(OR) and 95% confidence interval(CI). The level of significance was set at 5%(P ≤ 0.05).RESULTS Age equal to or over 62 years(OR = 8.79; 95%CI: 5.90-13.09, P < 0.01) and female gender(OR = 2.91; 95%CI: 1.74-4.37; P < 0.01) were associated with increased risk of SCRC. Analysis of the polymorphisms revealed an association between the GSTM1 polymorphisms and a risk of SCRC(OR = 1.45; 95%CI: 1.06-2.00; P = 0.02), as well as between GSTT1 and a reduced risk of the disease(OR = 0.65; 95%CI: 0.43-0.98; P = 0.04). An interaction between the presence of the wild-type allele of GSTP1 Ile105 Val polymorphism and tobacco consumption on risk of SCRC(OR = 2.33; 95%CI: 1.34-4.05; P = 0.05) was observed. There was an association between the GSTM1 null genotype and the presence of advanced tumors(OR = 2.33; 95%CI: 1.23-4.41; P = 0.009), as well as increased risk of SCRC in the presence of a combination of GSTT1 non-null/GSTM1 null genotypes(OR = 1.50; 95%CI: 1.03-2.19; P = 0.03) and GSTT1 non-null/GSTM1 null/GSTP1 Val~*(OR = 1.85; 95%CI: 1.01-3.36, P = 0.04). Combined GSTT1 non-null/GSTM1 null genotypes(OR = 2.40; 95%CI: 1.19-4.85; P = 0.01) and GSTT1 non-null/GSTM1 null/GSTP1 Val~*(OR = 2.92; 95%CI: 1.05-8.12; P = 0.04) were associated with tumor progression. Polymorphisms were not associated with the survival of patients with SCRC.CONCLUSION Females aged 62 years or older are more susceptible to SCRC. Polymorphisms of GSTT1 and GSTM1 null genotypes modulated the susceptibility to SCRC in the population studied. | Gabriela Helena Rodrigues-Fleming Glaucia Maria de Mendonca Fernandes Anelise Russo Patrícia Matos Biselli-Chicote Joao Gomes Netinho Erika Cristina Pavarino Eny Maria Goloni-Bertollo | 2018 | World Journal of Gastroenterology2018，24，39： | 1 |
| 12 | Physiological Adaptations to Strength and Circuit Training in Postmenopausal Women With Bone Loss显示文摘 | Michel A Brentano Eduardo L Cadore Eduardo M Da Silva Anelise B Ambrosini M Coertjens Rosemary Petkowicz Itamara Viero Luiz F M Kruel | 2008 | Journal of Strength and Conditioning Research2008，，6： | 1 |
| 13 | Toothache and associated factors in Brazilian adults: a cross-sectional population-based study显示文摘 | Mirian Kuhnen Marco A Peres Anelise V Masiero Karen G Peras | 2010 | 4(7) : 112-1212010，4，7： | 1 |
| 14 | Budel X - linked in- continentia pigmenti or Bloch - Sulzberger synctrome : A case report 显示文摘 | Pereira MAC de F Mesquita LA Anelise R | 2010 | An Bras Dermatol2010，85，3： | 1 |
| 15 | Traumatic Insistence:Reflections on the Concept of Negative in Psychoanalysis显示文摘The so-called non-neurotic pathologies have been widely studied,as they require clinical intervention different from the analytic process for cases of neurosis.This proposal focuses on the neurotic and psychotic structures with the concept of negative as an operator for metapsychological and clinical debate.The negative may be associated with the neurotic structure with respect to the establishment of repression,the action of defenses in distinguishing psychic systems,and the overbearing presence of word-presentations.In this structural dimension,free association and analytic interpretation operate by means of the cut,the negative and the excess libido found in symptomatic and traumatic insistence.Regarding the psychotic structure,the foreclosure of the paternal function does not inscribe a negative,causing the subject to be adrift in language,their unconscious out in the open air.In this sense,analytic intervention acts on the traumatic insistence of language,playing the role of secretary to the psychotic(Lacan,1955-56),helping them to weave ties and produce negatives before the invasive Other.Much research has focused on investigating the reverberation of trauma on psychic life as well as the unconscious content bordering on the drive-more specifically,the death drive and the idea of an excess.This communication proposal seeks in the concept of negative theoretical and technical elements to problematize these issues.For such,it analyzes the contributions of Freud,Lacan,and Green to the proposition that this concept can be considered an operator of metapsychological and technical reflection in traumatic insistence. | Ana Lúcia Mandelli de Marsillac Anelise Hauschild Mondardo | 2023 | Journal of Philosophy Study2023，13，6： | 0 |
| 16 | The Iron Ore Market in the Sino-Brazilian Trade显示文摘China has required a large quantity of commodities in order to keep with its economic growth path,driven by large exports,rapid urbanization and investment in fixed assets.Commodities exporter countries have benefited from China ’s immense'hunger'for commodities,especially during the 2000s.Brazil,for instance,has emerged in this scenario as one of the largest iron ore producers and exporters.However,the cooling down of the Chinese economy has brought doubts to the iron ore industry,which may remain strong in near future but one cannot claim for certain whether or not this trend will remain this positive in the long run. | ANELISE REZENDE DE MORAES | 2013 | 科技致富向导2013，，14： | 0 |
| 17 | Shade and sapling size influence restoration of Araucaria angustifolia显示文摘Toward improving reforestation of Brazilian pine(Araucaria angustifolia),two contrasting sapling sizes in either full sun or in the shade of a mixed plantation and the effect of opening the canopy were evaluated for survival,growth,gas exchange,photosynthetic pigments,and leaf anatomy 18 months after being planted.At 23 months after planting,a partial opening was made in the canopy in the mixed plantation,then the saplings were evaluated again after 2 months for the same morphophysiological traits.After 18 months,saplings planted in the full sun had higher survival,growth,pigments,and photosynthesis compared to the shaded saplings.Large saplings had higher survival and growth compared to the small ones.Shaded leaves were thinner and little differentiation of palisade parenchyma and hypodermis.After opening of the canopy,photo synthetically active radiation was 10 times higher,and the saplings quickly grew in height due to increased photosynthesis.Thus,although the species can tolerate shade,growth in the shade is limited.We recommend that for reforestation purposes of Brazilian pine,large saplings should be selected and planted in the open for better development. | Simone Aparecida Zolet Sasso JoséAbramo Marchese Amanda Pacheco Cardoso Moura Bruna Valéria Gil Anelise Tessari Perboni Joel Donazzolo Fabrícia Lorrane Rodrigues Oliveira Bruno Francisco Sant’Anna-Santos Angela Rohr Moeses Andrigo Danner | 2021 | Journal of Forestry Research2021，32，5： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员