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| 1 | Potential role of metabolomics in diagnosis and surveillance of gastric cancer显示文摘Gastric cancer is one of the deadliest cancers worldwide, and is especially prevalent in Asian countries. With such high morbidity and mortality, early diagnosis is essential to achieving curative intent treatment and long term survival. Metabolomics is a new field of study that analyzes metabolites from biofluids and tissue samples. While metabolomics is still in its infancy, there are numerous potential applications in oncology, specifically early diagnosis. Only a few studies in the literature have examined metabolomics' role in gastric cancer. Various fatty acid, carbohydrate, nucleic acid, and amino acid metabolites have been identified that distinguish gastric cancer from normal tissue and benign gastric disease. However, findings from these few studies are at times conflicting. Most studies demonstrate some relationship of cancer cells to the Warburg Effect, in that glycolysis predominates with conversion of pyruvate to lactate. This is one of the most consistent findings across the literature. There is less consistency in metabolomic signature with respect to nucleic acids, lipids and amino acids. In spite of this, metabolomics holds some promise for cancer surveillance but further studies are necessary to achieve consistency and validation before it can be widely employed as a clinical tool. | Angela W Chan Richdeep S Gill Daniel Schiller Michael B Sawyer | 2014 | World Journal of Gastroenterology2014，20，36： | 9 |
| 2 | Methanol removal efficiency and bacterial diversity of an activated carbon biofilter显示文摘 | Callie W B Adriana P Angela S Lindner | 2009 | Bioresour Techn2009，100，24： | 1 |
| 3 | Cardiac HCN chan-nels,structure,function,and modulation显示文摘 | Martin B Angela S Christian W | 2002 | Trends inCardiovascular Medicine2002，12，5： | 1 |
| 4 | Bacteria ingestion by Daphnia galeata in a biomanipulated reservoir:a mechanism stabilizing bioma- nipulation? 显示文摘 | Norbert K Angela B Clemens W | 1999 | Hydrobiologia1999，403，： | 1 |
| 5 | Chicken secure immune response to Salmonella enterica serovars of different levels of invasiveness显示文摘 | ANGELA B ANNE W CHRITIANE J | 2007 | Infect Immun2007，75，12： | 1 |
| 6 | Effective terminal sterilization using supercritieal carbon dioxide 显示文摘 | Angela W David B Tim W C | 2006 | Journal of Biotechnology2006，123，： | 1 |
| 7 | Effective terminal sterilization using supercritical carbon dioxide显示文摘 | Angela W David B Tim W C | 2006 | Journal of Biotechnology2006，4，： | 1 |
| 8 | Selecting Concrete Pavement Joint Sealant显示文摘 | ANGELA D R PEAR L S THEODORE W B | 1999 | Journal of Materials in Civil Engineering1999，11，4： | 1 |
| 9 | Viewing clinical research career development through the lens of social cognitive career theory显示文摘 | Lori L B Angela B W Minfen W | 2006 | Advances in Health Sciences Education2006，11，1： | 1 |
| 10 | Reliability assessment of continuously re- inforced concrete pavements显示文摘 | Weissmann Angela J McCullough B F Hudson W Ronald | 1994 | Journal of Transporta- tion Engineering1994，120，2： | 1 |
| 11 | Cardiac HCN channels,structure,function,and modulation显示文摘 | Martin B Angela S Christian W | 2002 | Trends in Cardiovascular Medicine2002，12，5： | 1 |
| 12 | Changes in systemic type 1 and type 2 immunity in normal pregnancy and pre-eclampsia may be mediatedby natural killer cells显示文摘 | Angela M Borzychowskil B Anne C W | 2005 | Eur J Immunol2005，35，： | 1 |
| 13 | Assessment of the potential suit- ability of selected commercially available enzymes for clean- ing-in-place(CIP)in the dairy industry显示文摘 | ANGELA B ANNA V P GARY W | 2010 | Biofouling2010，26，7： | 1 |
| 14 | Cytolethal distending toxin induced cell cycle arrest of lymphocytes is dependent upon recongnition and binding to cholesterol显示文摘 | Kathleen BB Angela B Lisa W | 2009 | J Biol Chem2009，284，16： | 1 |
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