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| 1 | Gestational weight gain and risk of gestational diabetes mellitus among Chinese women显示文摘 | Liu Zheng Ao Deng Yang Huixia Wang Yan | 2014 | Chinese Medical Journal2014，，7： | 42 |
| 2 | Metallothionein mediates cardioprotection of isoliquiritigenin against ischemia-reperfusion through JAK2/STAT3 activation显示文摘瞄准:检验 isoliquiritigenin (ISL ) 是否能稀释心肌的 ischemiareperfusion (MI/R ) 在由通过双面联胎激酶的激活导致 metallothionein (MT ) 的老鼠的损害 2 (JAK 2 )/signal 变换器和抄写 3 的使活跃之物(STAT 3 ) 小径。方法:在老鼠的 MI/R 的试验性的模型被局部缺血和灌注的 30 min 为 2 h 产生。MT, COX-2,和 i NOS 的 mRNA 表示被 RT-PCR 测量。MT, JAK/STAT,细胞外的调整信号的激酶(英皇家空军之阶级最低之兵) ,和 Akt 的蛋白质表情被在一个 JAK 激酶禁止者的缺席或存在的西方的弄污决定, tyrphostin AG490 (1.0 mg/kg, iv,在局部缺血前的 1 h ) 。结果:有 ISL 的预告的处理显著地减少了导致 reperfusion 的心律不齐和心肌的梗塞尺寸的严厉。在 ISL 20 mg/kg 组,当时, lactate 脱氢酶(LDH ) 和肌酸酐磷酸激酶(CPK ) 的活动被 38.4% 和 51.3% 减少与车辆组相比。增加的 JAK 2/STAT 3 磷酸化被 MT 然而并非 COX-2 或 i NOS 的增加的合成在对待 ISL 的组伴随。AG490 能显著地削弱导致 ISL 的 cardioprotection 并且阻止 MT 表示和 JAK 2/STAT 的增加 3 磷酸化。结论:ISL 通过 JAK 2/STAT 的激活保护了 MI/R 损害 3 信号转导变异小径,它可能涉及调停起来 MT 的规定表示。 | Wei AN Jing YANG Ying AO | 2006 | Acta Pharmacologica Sinica2006，27，11： | 23 |
| 3 | Factors affecting proprioceptive recovery after anterior cruciate ligament reconstruction显示文摘背景 Proprioception 戏在在那里的膝 movements.Since 的一个重要角色是包围 proprioception 追随者外科的全面恢复时间的争吵,在以后,定义影响 proprioceptive 恢复的因素是必要的前面的十字形的系带( ACL )重建并且有他们的 ACL 的 36 个病人的一个总数与 semitendinosus/gracilis 接枝重建了调查在 proprioception 和肌肉 strength.Methods 之间的关系(重建的 group:6 | ZHOU Mou-wang GU Li CHEN Ya-ping YU Chang-long AO Ying-fang HUANG Hong-shi YANG Yan-yan | 2008 | Chinese Medical Journal2008，，22： | 22 |
| 4 | Anatomy of composition and nature of plate convergence: Insights for alternative thoughts for terminal India-Eurasia collision显示文摘The pattern and timing of collision between India and Eurasia have long been a major concern of the international community. However, no consensus has been reached hitherto. To explore and resolve the disagreements in the Himalayan study,in this paper we begin with the methodology and basic principles for the anatomy of composition and nature of convergent margins,then followed by an effort to conduct a similar anatomy for the India-Eurasia collision. One of the most common patterns of plate convergence involves a passive continental margin, an active continental margin and intra-oceanic basins together with accreted terranes in between. The ultimate configuration and location of the terminal suture zone are controlled by the basal surface of the accretionary wedge, which may show fairly complex morphology with Z-shape and fluctuant geometry. One plausible method to determine the terminal suture zone is to dissect the compositions and structures of active continental margins. It requires a focus on various tectonic elements belonging to the upper plate, such as accretionary wedges, high-pressure(HP)-ultra-high-pressure(UHP) metamorphic rocks, Barrovian-type metamorphic rocks and basement nappes, together with superimposed forearc basins.Such geological records can define the extreme limits and the intervening surface separating active margin from the passive one,thus offering a general sketch for the surface trace of the terminal suture zone often with a cryptic feature. Furthermore, the occurrence of the cryptic suture zone in depth may be constrained by geophysical data, which, in combination with outcrop studies of HP-UHP metamorphic rocks, enables us to outline the terminal suture zone. The southern part of the Himalayan orogen records complicated temporal and spatial features, which are hard to be fully explained by the classic 'two-plate-one-ocean' template,therefore re-anatomy of the compositions and nature for this region is necessitated. Taking advantage of the methodology and basic principles of plate convergence anatomy and synthesizing previous studies together with our recent research, we may gain new insights into the evolution of the Himalayan orogeny.(1) The Yarlung-Zangbo ophiolite is composed of multiple tectonic units rather than a single terminal suture zone, and a group of different tectonic units were juxtaposed against each other in the backstop of the Gangdese forearc.(2) The Tethyan Himalayan Sequence(THS) contains mélanges with typical block-in-matrix structures, uniform southwards paleocurrents and age spectra of detrital zircons typical of Eurasia continent. All of these facts indicate that the THS belonged to Eurasia plate before the terminal collision, emplaced in the forearc of the Gangdese arc.(3) The Greater Himalayan Crystalline Complex(GHC) and Lesser Himalayan Sequence(LHS) comprise complex components including eclogites emplaced into the GHC and the upper part of the LHS. Judging from the fact that HP-UHP metamorphic rocks are exhumed and emplaced in the upper plate, the GHC and the upper part of the LHS where eclogite occur should be assigned to the upper plate, lying above the terminal subduction zone surface. It is the very surface along which the continuous subduction of the India subcontinent occurred, therefore acting as the terminal, cryptic suture. From the suture further southward, the bulk rock associations of the LHS and Sub-Himalayan Sequence(Siwalik) show little affinity of mélange, probably belonging to the foreland system of the India plate. By the anatomy of tectonic features of all the tectonic units in the Himalayan orogen as well as the ages of the subduction-accretion related deformation, we conclude that the terminal India-Eurasia collision occurred after 14 Ma, the timing of the metamorphism of the eclogites emplaced into the upper plate. The development of rifts stretching in N-S direction in Tibet and tectonic events with the transition from sinistral to dextral movements in shear zones, such as the Ailaoshan fault in East Tibet, can coordinately reflect the scale and geodynamic influence of the India-Eurasia convergence zone.By conducting a detailed anatomy of the southern Himalayas, we propose a new model for the final collision-accretion of the Himalayan orogeny. Our study indicates that the anatomy of structures, composition, and tectonic nature is the key to a better understanding of orogenic belts, which may apply to all the orogenic belts around the world. We also point out that several important issues regarding the detailed anatomy of the structures, compositions and tectonic nature of the Himalayan orogeny in future. | XIAO WenJiao AO SongJian YANG Lei HAN ChunMing WAN Bo ZHANG Ji'En ZHANG ZhiYong LI Rui CHEN ZhenYu SONG ShuaiHua | 2017 | Science China Earth Sciences2017，60，6： | 20 |
| 5 | Prevalence of Developmental Dysplasia of the Hip in Chinese Adults: A Cross-sectional Survey显示文摘 | Feng-De Tian De-Wei Zhao Wei Wang Lin Guo Si-Miao Tian Ao Feng Fan Yang Dong-Yi Li | 2017 | Chinese Medical Journal2017，，11： | 18 |
| 6 | Water regime-nitrogen fertilizer incorporation interaction:Field study on methane and nitrous oxide emissions from a rice agroecosystem in Harbin, China显示文摘Water regime and nitrogen(N) fertilizer are two important factors impacting greenhouse gases(GHG) emission from paddy field, whereas their effects have not been well studied in cold region. In this study, we conducted a two-year field experiment to study the impacts of water regime and N fertilizer on rice yields and GHG emissions in Harbin, China, a cold region located in high latitudes. Our results showed that intermittent irrigation significantly decreased methane(CH_4) emission compared with continuous flooding, however,the decrement was far lower than the global average level. The N_2O emissions were very small when flooded but peaked at the beginning of the disappearance of floodwater. The N fertilizer treatments increased CH_4 emissions at low level(75 kg N/ha). But both CH_4 and N_2O emissions were uninfluenced at the levels of 150 kg N/ha and 225 kg N/ha. Rice yields increased under intermittent irrigation and were highest at the level of 150 kg N/ha. From our results, we recommended that the intermittent irrigation and 150 kg N/ha as the ideal water regime-nitrogen fertilizer incorporation for this area to achieve low GHG emissions without impacting rice yields. | Wenjun Dong Jia Guo Lijun Xu Zhifeng Song Jun Zhang Ao Tang Xijuan Zhang Chunxu Leng Youhong Liu Lianmin Wang Lizhi Wang Yang Yu Zhongliang Yang Yilei Yu Ying Meng Yongcai Lai | 2018 | Journal of Environmental Sciences2018，30，2： | 12 |
| 7 | Cytocompatibility with osteogenic cells and enhanced in vivo anti-infection potential of quaternized chitosan-loaded titania nanotubes显示文摘Infection is one of the major causes of failure of orthopedic implants. Our previous study demonstrated that nanotube modification of the implant surface, together with nanotubes loaded with quaternized chitosan(hydroxypropyltrimethyl ammonium chloride chitosan, HACC), could effectively inhibit bacterial adherence and biofilm formation in vitro. Therefore, the aim of this study was to further investigate the in vitro cytocompatibility with osteogenic cells and the in vivo anti-infection activity of titanium implants with HACC-loaded nanotubes(NT-H). The titanium implant(Ti), nanotubes without polymer loading(NT), and nanotubes loaded with chitosan(NT-C) were fabricated and served as controls. Firstly, we evaluated the cytocompatibility of these specimens with human bone marrow-derived mesenchymal stem cells in vitro.The observation of cell attachment, proliferation, spreading, and viability in vitro showed that NT-H has improved osteogenic activity compared with Ti and NT-C. A prophylaxis rat model with implantation in the femoral medullary cavity and inoculation with methicillin-resistant Staphylococcus aureus was established and evaluated by radiographical, microbiological, and histopathological assessments. Our in vivo study demonstrated that NT-H coatings exhibited significant anti-infection capability compared with the Ti and NT-C groups. In conclusion, HACC-loaded nanotubes fabricated on a titanium substrate show good compatibility with osteogenic cells and enhanced anti-infection ability in vivo, providing a good foundation for clinical application to combat orthopedic implant-associated infections. | Ying Yang Haiyong Ao Yugang Wang Wentao Lin Shengbing Yang Shuhong Zhang Zhifeng Yu Tingting Tang | 2016 | Bone Research2016，4，3： | 9 |
| 8 | Adsorption characteristics of a novel ceramsite for heavy metal removal from stormwater runoff显示文摘Urban sediments have rapidly increased in recent years around the world,and their effective management has become an important problem.To remove heavy metals from stormwater runoff and use sediments as a resource,a novel ceramsite was developed using sewer pipe sediments(SPS),river bed sediments(RBS),urban water supply treatment sludge(WSTS),and wastewater treatment plant excess sludge(WWTS).The optimal composition was determined based on the Brunauer–Emmett–Teller specific surface area and an orthogonal test design.The adsorption characteristics of the novel ceramsite for dissolved heavy metals(Cu^(2+)and Cd^(2+)) were investigated through adsorption isotherms and kinetic experiments at(25±1)℃.Both Cu^(2+) and Cd^(2+) were effectively removed by the novel ceramsite,and their equilibrium adsorption was 4.96 mg·g^(-1) and 3.84 mg·g^(-1),respectively.Langmuir isotherms and a pseudo-first-order kinetic equation described the adsorption process better than other techniques.Characterization analysis of the ceramsite composition before and after heavy metal adsorption showed that the Cu^(2+) and Cd^(2+) contents in the ceramsite increased after adsorption.The results revealed that adsorption is both a physical and chemical process,and that ceramsite can be used as a bioretention medium to remove heavy metals from stormwater runoff while simultaneously converting problematic urban sediments into a resource. | Jianlong wang Yuanling Zhao Pingping Zhang Liqiong Yang Huai'ao Xu Guangpeng Xi | 2018 | Chinese Journal of Chemical Engineering2018，26，1： | 9 |
| 9 | Lead?Free Halide Double Perovskite Materials: A New Superstar Toward Green and Stable Optoelectronic Applications显示文摘Lead-based halide perovskites have emerged as excellent semiconductors for a broad range of optoelectronic applications, such as photovoltaics, lighting, lasing and photon detection. However, toxicity of lead and poor stability still represent significant challenges. Fortunately, halide double perovskite materials with formula of A_2M(I)M(III)X_6 or A_2M(IV)X_6 could be potentially regarded as stable and green alternatives for optoelectronic applications, where two divalent lead ions are substituted by combining one monovalent and one trivalent ions, or one tetravalent ion. Here, the article provides an up-to-date review on the developments of halide double perovskite materials and their related optoelectronic applications including photodetectors, X-ray detectors, photocatalyst, light-emitting diodes and solar cells. The synthesized halide double perovskite materials exhibit exceptional stability, and a few possess superior optoelectronic properties. However, the number of synthesized halide double perovskites is limited, and more limited materials have been developed for optoelectronic applications to date. In addition, the band structures and carrier transport properties of the materials are still not desired, and the films still manifest low quality for photovoltaic applications. Therefore, we propose that continuing e orts are needed to develop more halide double perovskites, modulate the properties and grow high-quality films, with the aim of opening the wild practical applications. | Liang Chu Waqar Ahmad Wei Liu Jian Yang Rui Zhang Yan Sun Jianping Yang Xing'ao Li | 2019 | Nano-Micro Letters2019，11，1： | 8 |
| 10 | Identification,bioinformatic analysis and expression profiling of candidate mRNA-like non-coding RNAs in Sus scrofa显示文摘Messenger RNA-like non-coding RNAs(mlncRNAs) are a newly identified group of non-coding RNAs(ncRNAs) that may be in-volved in a number of critical cellular events.In this study,93 candidate porcine mlncRNAs were obtained by computational prediction and screening,among which 72 were mapped to the porcine genome.Further analysis of 8 representative candidates revealed that these mlncRNA candidates are not highly conserved among species.Remarkably,one of the candidates,sTF35495,was found to be precursor of a putative porcine microRNA.By RACE PCR,we determined that the full length of sTF35495 was 3 kb.The protein-coding potential of this RNA was tested in silico with no significant finding.Semi-quantitative RT-PCR analysis of the subgroup of 8 candidates revealed two distinct expression profiles and two molecules were further validated by real-time PCR.The predicted pre-microRNA sequence in this study provides a potentially interesting insight into the in vivo function of porcine mlncRNAs and our findings suggest that they play key biological roles in Sus scrofa. | Bang Xiao Xingju Zhang Yong Li Zhonglin Tang Shulin Yang Yulian Mu Wentao Cui Hong Ao Kui Li | 2009 | Journal of Genetics and Genomics2009，36，12： | 7 |
| 11 | ESTIMATION METHOD ON THE BATTERY STATE OF CHARGE FOR HYBRID ELECTRIC VEHICLE显示文摘A combined algorithm for battery state of charge(SOC)estimation is proposed to solve the critical issue of hybrid electric vehicle(HEV).To obtain a more accurate SOC,both coulomb-accumulation and battery resistance-capacitor(RC)model are weighted combined to compensate the deficiencies of individual methods.In order to solve the key issue of coulomb-accumulation,the battery thermal model is used.Based on the principle of energy conservation,the heat generated from battery charge and discharge process is converted into the equivalent electricity to calculate charge and discharge efficiency under variable current.The extended Kalman filter(EKF)as a closed loop algorithm is applied to estimate the parameters of resistance-capacitor model.The input variables do not increase much computing difficulty.The proposed combined algorithm is implemented by adjusting the weighting factor of coulomb- accumulation and resistance-capacitor model In the end,four different methods including Ah-efficiency,Ah-Equip,RC-SOC and Combined-SOC are compared in federal testing procedure (FTP)drive cycle.The experiment results show that the proposed method has good robustness and high accuracy which is suitable for HEV application. | QIANG Jiaxi AO Guoqiang YANG Lin | 2008 | Chinese Journal of Mechanical Engineering2008，21，3： | 7 |
| 12 | Targeted therapy for hepatocellular carcinoma显示文摘The last 3 years have seen the emergence of promising targeted therapies for the treatment of hepatocellular carcinoma(HCC).Sorafenib has been the mainstay of treatment for a decade and newer modalities were ineffective and did not confer any increased therapeutic benefit until the introduction of lenvatinib which was approved based on its non-inferiority to sorafenib.The subsequent success of regorafenib in HCC patients who progress on sorafenib treatment heralded a new era of second-line treatment and was quickly followed by ramucirumab,cabozantinib,and the most influential,immune checkpoint inhibitors(ICIs).Over the same period combination therapies,including anti-angiogenesis agents with ICIs,dual ICIs and targeted agents in conjunction with surgery or other loco-regional therapies,have been extensively investigated and have shown promise and provided the basis for exciting clinical trials.Work continues to develop additional novel therapeutic agents which could potentially augment the presently available options and understand the underlying mechanisms responsible for drug resistance,with the goal of improving the survival of patients with HCC. | Ao Huang Xin-Rong Yang Wen-Yuan Chung Ashley R.Dennison Jian Zhou | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 7 |
| 13 | Comprehensive circRNA-microRNA-mRNA network analysis revealed the novel regulatory mechanism of Trichosporon asahii infection显示文摘Background:Invasive Trichosporon asahii(T.asahii)infection frequently occurs with a high mortality in immunodeficient hosts,but the pathogenesis of T.asahii infection remains elusive.Circular RNAs(circRNAs)are a type of endogenous noncoding RNA that participate in various disease processes.However,the mechanism of circRNAs in T.asahii infection remains completely unknown.Methods:RNA sequencing(RNA-seq)was performed to analyze the expression profiles of circRNAs,microRNAs(miRNAs),and mRNAs in THP-1 cells infected with T.asahii or uninfected samples.Some of the RNA-seq results were verified by RT-qPCR.Gene Ontology(GO)enrichment and Kyoto Encyclopedia of Genes and Genomes(KEGG)pathway analyses were used to analyze the differentially expressed mRNAs.A circRNA-miRNA-mRNA network was constructed and verified by dual-luciferase reporter assay and overexpression experiments.Results:A total of 46 circRNAs,412 mRNAs and 47 miRNAs were differentially expressed at 12 h after T.asahii infection.GO and KEGG analyses showed that the differentially expressed mRNAs were primarily linked to the leukocyte migration involved in the inflammatory response,the Toll-like receptor signaling pathway,and the TNF signaling pathway.A competing endogenous RNA(ceRNA)network was constructed with 5 differentially expressed circRNAs,5 differentially expressed miRNAs and 42 differentially expressed mRNAs.Among them,hsa_circ_0065336 was found to indirectly regulate PTPN11 expression by sponging miR-505-3p.Conclusions:These data revealed a comprehensive circRNA-associated ceRNA network during T.asahii infection,thus providing new insights into the pathogenesis of the T.asahii-host interactions. | Ming-Wang Zhang Zhi-Hong Zhu Zhi-Kuan Xia Xin Yang Wan-Ting Luo Jun-Hong Ao Rong-Ya Yang | 2021 | Military Medical Research2021，8，4： | 6 |
| 14 | Extractive distillation: Advances in conceptual design, solvent selection,and separation strategies显示文摘Extractive distillation(ED) is one of the most promising approaches for the separation of the azeotropic or closeboiling mixtures in the chemical industry. The purpose of this paper is to provide a broad overview of the recent development of key aspects in the ED process involving conceptual design, solvent selection, and separation strategies. To obtain the minimum entrainer feed flow rate and reflux ratio for the ED process, the conceptual design of azeotropic mixture separation based on a topological analysis via thermodynamic feasibility insights involving residue curve maps, univolatility lines, and unidistribution curves is presented. The method is applicable to arbitrary multicomponent mixtures and allows direct screening of design alternatives. The determination of a suitable solvent is one of the key steps to ensure an effective and economical ED process. Candidate entrainers can be obtained from heuristics or literature studies while computer aided molecular design(CAMD) has superiority in efficiency and reliability. To achieve optimized extractive distillation systems, a brief review of evaluation method for both entrainer design and selection through CAMD is presented. Extractive distillation can be operated either in continuous extractive distillation(CED) or batch extractive distillation(BED), and both modes have been well-studied depending on the advantages in flexibility and low capital costs. To improve the energy efficiency, several configurations and technological alternatives can be used for both CED and BED depending on strategies and main azeotropic feeds. The challenge and chance of the further ED development involving screening the best potential solvents and exploring the energy-intensive separation strategies are discussed aiming at promoting the industrial application of this environmentally friendly separation technique. | Shirui Sun Liping Lü Ao Yang Shun'an Wei Weifeng Shen | 2019 | Chinese Journal of Chemical Engineering2019，27，6： | 6 |
| 15 | Dynamic Expression of MicroRNA-127 During Porcine Prenatal and Postnatal Skeletal Muscle Development显示文摘MicroRNAs(miRNAs), evolutionarily conserved non-coding RNAs in length 21-24 bp, play a critical role in skeletal muscle development. In this study, to explore the function of mircoRNA-127 in porcine skeletal muscle development, eight tissue samples from adult pigs and longissimus muscle samples at 26 developmental stages were collected from Tongcheng and Landrace pigs. The spatial-temporal expression profiles of miRNA-127 were carried out using step-loop quantitative real-time PCR(stemloop RT-PCR). To explore the molecular functions of miRNA-127, we predicted its target genes and performed functional annotation using bioinformatics methods. Results suggested that miRNA-127 was abundantly expressed in heart, ovary, uterus and spleen tissues and was weakly expressed in liver, lung, kidney and small intestine in both Tongcheng and Landrace pigs. And miRNA-127 showed significant expression differences in heart, ovary, spleen and uterus tissues between these two breeds. miRNA-127 basically kept at a relatively stable high level in middle and later embryonic stages and a low expression level in early embryonic stages and postnatal stages, but the expression levels of miRNA-127 were higher in Tongcheng pigs than in Landrace at most developmental stages. miRNA-127 potentially regulated 240 candidate genes. Results of Gene Ontology and KEGG pathway analysis indicated that these genes could be involved in many molecular functions and mechanisms, such as regulation of the force of heart contraction, regulation of transcription, regulation of T cell differentiation, MAPK signaling pathway and GnRH signaling pathway. Many significantly enriched GO terms and KEGG pathways were related to skeletal muscle development. This study will be helpful to understand the biological function for miRNA-127 and identify candidate gene associated with meat production traits in pigs. | YANG Ya-lan LI Yan LIANG Ru-yi ZHOU Rong AO Hong MU Yu-lian YANG Shu-lin LI Kui TANG Zhong-lin | 2014 | Journal of Integrative Agriculture2014，13，6： | 6 |
| 16 | Blockchain-Based Secure Distributed Control for Software Defined Optical Networking显示文摘Software defined optical networking(SDON)is a critical technology for the next generation network with the advantages of programmable control and etc.As one of the key issues of SDON,the security of control plane has also received extensive attention,especially in certain network scenarios with high security requirement.Due to the existence of vulnerabilities and heavy overhead,the existing firewalls and distributed control technologies cannot solve the control plane security problem well.In this paper,we propose a distributed control architecture for SDON using the blockchain technique(BlockCtrl).The proposed BlockCtrl model introduces the advantages of blockchain into SDON to achieve a high-efficiency fault tolerant control.We have evaluated the performance of our proposed architecture and compared it to the existing models with respect to various metrics including processing rate,recovery latency and etc.The numerical results show that the BlockCtrl is capable of attacks detection and fault tolerant control in SDON with high performance on resource utilization and service correlation. | Hui Yang Yongshen Liang Qiuyan Yao Shaoyong Guo Ao Yu Jie Zhang | 2019 | China Communications2019，16，6： | 5 |
| 17 | AI_4C_3 Hydration Thermochemical Analysis for Burned Carbon-containing Refractories with Al显示文摘In this paper, X-ray diffractogram analysis and SEM observation of Al4 C3 formed at high temperature from carbon-containing refractories with Al have been carried out.Aluminum added to carbon-containing refractories reacts with C(s)to form Al4 C3(s) gradually during heating from 600 ℃ to 1200℃.It is considered that the interlocked structure of Al4 C3 plate crystals promotes the outstanding increase of hot modulus of rupture of carbon-containing refractories with Al. The HMOR of carbon-containing refractories added with Al additive from 0 to 5wt% increases by 2.8 times being from 6.5MPa to 18.2MPa.After a thermochemical calculation for hydration reaction processes of Al4 C3 and H2O(g), the equilibrium partial pressure chart of H2O(g)in H2O-Al4C3-Al(OH)3 system vs various temperatures has been attained . The H2O (g) partial pressure in the air needed for the Al4 C3 hydration reaction is no more than 10~18 atm at the temperature below 120℃.It is considered that the burned carbon-containing refractories with Al is extremely easy to hydrate and the cracking of burned carbon-containing refractories is generated because that the hydration expansion is 2.11 times during transforming from Al4 C3 to Al(OH)3.The fundamental measure against hydration of the refractories is to insulate the refractories from H2O(g)by various means such as pitch impregnation or other sealing materials. | YANG Ding’ao, YU Zhiming and FAN Liuwu( Sanmenxia Polytechnic College, Sanmenxia, Henan 472000, China ) | 2003 | China's Refractories2003，12，1： | 5 |
| 18 | Edgence: A Blockchain-Enabled Edge-Computing Platform for Intelligent IoT-Based dApps显示文摘Nowadays scalable Io T management is a bottleneck of Io T development due to the geographically dispersed distribution, fragmented ownerships, and ever-growing population of Io T devices. To intelligently manage massive decentralized applications(d Apps) in Io T usecases, Edgence(EDGe + intellig ENCE) is proposed to use edge clouds to access Io T devices and users, and then use its in-built blockchain to realize self-governing and self-supervision of the edge clouds. Edgence proposes to use masternode technology to introduce Io T devices and users into a closed blockchain system, which can extend the range of blockchain to Io T-based d Apps. Further, masternodes do good to scalability by raising the TPS(transactions per second) of the blockchain network. To support various d Apps, a three-tier validation is proposed, namely script validation, smartcontract validation, and masternode validation. To avoid energy consumption resulted by blockchain consensus, Edgence proposes a random but verifiable way to elect a masternode to generate each new block. The potential of the tailored Edgence is shown by examples of decentralized crowdsourcing and AI training. | Jinliang Xu Shangguang Wang Ao Zhou Fangchun Yang | 2020 | China Communications2020，17，4： | 5 |
| 19 | A new cerebroside and its anti-proliferation effect on VSMCs from the radix of Cyperus rotundus L.显示文摘A new cerebroside,1-O-(β-D-glucopyranosyloxy)-(2S,3R,4E,8Z)-2-[(2′R)-2’-hydroxylignoceranoylamino]-4,8-tetradecene-3- diol was isolated from the 60%EtOH extract of traditional Chinese medical plant Cyperus rotundus L.Its structure was determined on the basis of spectroscopic data.This new compound showed anti-proliferation effect on vascular smooth muscle cells(VSMCs). | Pei Liu Li Liu Yu Ping Tang Jin Ao Duan Nian Yun Yang | 2010 | Chinese Chemical Letters2010，21，5： | 5 |
| 20 | Lateral Hypothalamic Area Glutamatergic Neurons and Their Projections to the Lateral Habenula Modulate the Anesthetic Potency of Isoflurane in Mice显示文摘The lateral hypothalamic area(LHA)plays a pivotal role in regulating consciousness transition,in which orexinergic neurons,GABAergic neurons,and melanin-concentrating hormone neurons are involved.Glutamatergic neurons have a large population in the LHA,but their anesthesia-related effect has not been explored.Here,we found that genetic ablation of LHA glutamatergic neurons shortened the induction time and prolonged the recovery time of isoflurane anesthesia in mice.In contrast,chemogenetic activation of LHA glutamatergic neurons increased the time to anesthesia and decreased the time to recovery.Optogenetic activation of LHA glutamatergic neurons during the maintenance of anesthesia reduced the burst suppression pattern of the electroencephalogram(EEG)and shifted EEG features to an arousal pattern.Photostimulation of LHA glutamatergic projections to the lateral habenula(LHb)also facilitated the emergence from anesthesia and the transition of anesthesia depth to a lighter level.Collectively,LHA glutamatergic neurons and their projections to the LHb regulate anesthetic potency and EEG features. | Shiyi Zhao Rui Li Huiming Li Sa Wang Xinxin Zhang Dan Wang Juan Guo Huihui Li Ao Li Tingting Tong Haixing Zhong Qianzi Yang Hailong Dong | 2021 | Neuroscience Bulletin2021，37，7： | 5 |
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