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| 1 | Comparison of operative link for gastritis assessment, operative link on gastric intestinal metaplasia assessment, and TAIM stagings among men with atrophic gastritis显示文摘BACKGROUND Gastric cancer is the world’s third most lethal malignancy. Most gastric cancers develop through precancerous states of atrophic gastritis and intestinal metaplasia. Two staging systems, operative link for gastritis assessment(OLGA)and operative link on gastric intestinal metaplasia assessment(OLGIM), have been developed to detect high gastric cancer risk. European guidelines recommend surveillance for high-risk OLGA/OLGIM patients(stages Ⅲ–Ⅳ),and for those with advanced stage of atrophic gastritis in the whole stomach mucosa. We hypothesize, that by combining atrophy and intestinal metaplasia into one staging named TAIM, more patients with increased gastric cancer risk could be detected.AIM To evaluate the clinical value of the OLGA, OLGIM, and novel TAIM stagings as prognostic indicators for gastric cancer.METHODS In the Helsinki Gastritis Study, 22346 elderly male smokers from southwestern Finland were screened for serum pepsinogen I(PGI). Between the years 1989 and1993, men with low PGI values(PGI < 25 μg/L), were invited to undergo an oesophagogastroduodenoscopy. In this retrospective cohort study, 1147 men that underwent gastroscopy were followed for gastric cancer for a median of 13.7 years, and a maximum of 27.3 years. We developed a new staging system, TAIM,by combining the topography with the severity of atrophy or intestinal metaplasia in gastric biopsies. In TAIM staging, the gastric cancer risk is classified as low or high.RESULTS Twenty-eight gastric cancers were diagnosed during the follow-up, and the incidence rate was 1.72 per 1000 patient-years. The cancer risk associated positively with TAIM [Hazard ratio(HR) 2.70, 95%CI: 1.09–6.69, P = 0.03]. The risk increased through OLGIM stages 0-Ⅳ(0 vs Ⅳ: HR 5.72, 95%CI: 1.03–31.77, P for trend = 0.004), but not through OLGA stages 0–Ⅳ(0 vs Ⅳ: HR 5.77, 95%CI:0.67–49.77, P for trend = 0.10). The sensitivities of OLGA and OLGIM stages Ⅲ–Ⅳ were low, 21% and 32%, respectively, whereas that of TAIM high-risk was good, 79%. On the contrary, OLGA and OLGIM had high specificity, 85% and81%, respectively, but TAIM showed low specificity, 42%. In all three staging systems, the high-risk men had three-to four-times higher gastric cancer risk compared to the general male population of the same age.CONCLUSION OLGIM and TAIM stagings show prognostic value in assessing gastric cancer risk in elderly male smokers with atrophic gastritis. | Anna A Nieminen Jukka Kontto Pauli Puolakkainen Jarmo Virtamo Arto Kokkola | 2020 | World Journal of Gastroenterology2020，26，24： | 7 |
| 2 | Helicobacter pylori infection and low serum pepsinogen I level as risk factors for gastric carcinoma显示文摘AIM: To study whether examination of CagA antibodies could increase the odds ratio for gastric cancer in a casecontrol study, and how often other serum markers of gastric cancer risk could be found in Helicobacter pylorinegative patients.METHODS: H pylori CagA and parietal cell antibodies(PCAs), and serum pepsinogen Ⅰ (SPGI) levels were compared between patients with gastric cancer and controls who received endoscopic examination due to reasons other than gastrointestinal malignancy.RESULTS: The odds ratio (OR) for gastric cancer was2.9 (95% CI 1.4-5.8) in H pylori+ patients, and 2.4 (95%CI 1.2-4.9) in CagA+ patients. When results of H pylori and CagA antibodies were combined, OR increased to5.0 (95% CI 2.5-10.0). Furthermore, if cardia cancer patients were excluded, the OR increased to 6.8 (95% CI3.1-14.8). Among patients with a low SPGI level, the OR was 12.0 (95% CI 4.1-35.3). However, the risk was significant only in the older age group. The number of patients with low SPGI was significantly higher in H pylori-/CagA+ patients as compared to other cancer patients.CONCLUSION: Examination of both H pylori and CagA antibodies increases the OR for gastric cancer in our casecontrol study. CagA antibodies are important in detecting previous H pylori infection in advanced atrophic gastritis or cancer when spontaneous decline of H pylori antibodies occurs. SPGI may be helpful in screening elderly gastric cancer patients. | Arto Kokkola Johanna Louhimo Pauli Puolakkainen Henrik Alfthan Caj Haglund Hilpi Rautelin | 2005 | World Journal of Gastroenterology2005，11，7： | 6 |
| 3 | Selective recognition of aromatic hydrocarbons by endo-functionalized molecular tubes via C/N-H…π interactions显示文摘Molecular recognition of aromatic hydrocarbons by four endo-functionalized molecular tubes has been studied by ~1H NMR spectroscopy, computational methods, and single crystal X-ray crystallography. The binding selectivity is rationalized by invoking shape complementarity and dipole alignment. The noncovalent interactions are proved to predominantly be C/N-H…π interactions. | Guo-Bao Huang Wei-Er Liu Arto Valkonen Huan Yao Kari Rissanen Wei Jiang | 2018 | Chinese Chemical Letters2018，29，1： | 2 |
| 4 | Selective Recognition of Phenazine by 2,6-Dibutoxylnaphthalene-Based Tetralactam Macrocycle显示文摘A 2,6-dibutoxylnaphthalene-based tetralactam macrocycle was designed and synthesized.This macrocycle shows highly selective recognition to phenazine-a well-known secondary metabolite in bacteria and an emerging disinfection byproduct in drinking water.In contrast,the macrocycle shows no binding to the structurally similar dibenzo-1,4-dioxin.It was revealed that hydrogen bonding,π-π and σ-π interactions are the major driving forces between phenazine and the new tetralactam macrocycle.A perfect complementarity in electrostatic potential surfaces may explain the high selectivity.In addition,the macrocycle shows fluorescent response to phenazine,demonstrating its potential in fluorescent detection of phenazine. | Li-Li Wang Yi-Kuan Tu Arto Valkonen Kari Rissanen Wei Jiang | 2019 | Chinese Journal of Chemistry2019，37，9： | 2 |
| 5 | 儿童通过2年校园基础计划形成的预期信念和主观任务值及其与体育课喜爱程度和体力活动的关系(英文)显示文摘目的:本研究旨在分析通过实施以'体力活动作为国民技能'计划形成的儿童预期信念与主观任务值模式,并探索其与体育课程喜爱程度和体力活动总量相关联。方法:研究样本包含芬兰东北部3个小城镇的401名9-13岁儿童。这些儿童在五至七年级2年时间内接受校园基础体力活动培养计划。2012-2014年通过3个阶段的问卷调查获得数据。结果:该计划成功的预期信念和主观任务价值水平都相对较高且发展稳定,特别在预期信念、实现价值和成本方面,而兴趣值和实用价值在特定阶段内下降。男生普遍认为自己身体素质比别人更具竞争力,而且比女生更加重视体力活动课程。此外,学生报告参与的体力活动越多,越喜爱体育课程。结论:当前的计划包括通过采用心理及生理校园环境调整提高学生体力活动,本研究表明该计划是防止儿童预期信念和任务值水平下降的有效策略。 | Arto Gr?stén | 2016 | Journal of Sport and Health Science2016，5，4： | 2 |
| 6 | International Trade, Entrepreneurship, and Monopolistic Competition: German Hidden Champions and Global Markets显示文摘 | Arto Lahti | 2014 | China-USA Business Review2014，13，9： | 2 |
| 7 | The IFC Standard-a Review of History, Development, and Standardization 显示文摘 | Mikael Laakso Arto Kiviniemi | 2012 | Journal of Information Technology in Construction2012，，： | 1 |
| 8 | Ceramic - filter behavior in gasification显示文摘 | Lehtovaara Arto | 1993 | Bio- resource Technol1993，46，： | 1 |
| 9 | Cc ra m is filter behavior in gasification 显示文摘 | Lehtovaara Arto | 1993 | Bio - resource Technol1993，46，： | 1 |
| 10 | Putative surface proteins encoded within a novel transferable locus confer a high-biofilm phenotype to enterococcus faecalis显示文摘 | Preeti MT Arto SB Nathan S | 2006 | J Bacteriol2006，188，6： | 1 |
| 11 | Selective muscle hypertrophy, changes in EMG and force, and serum hormones during strength training in older women显示文摘 | Arto Pakarinen | 2001 | Journal of applied physiology2001，91，2： | 1 |
| 12 | Cryptographic protocols for Vickrey auctions显示文摘 | Hannu Nurmi Arto Salomaa | 1993 | Group Decision and Negotiation1993，，4： | 1 |
| 13 | Surgical or Nonoperative Treatment for Lumbar Spinal Stenosis?: A Randomized Controlled Trial显示文摘 | Antti Malmivaara P?r Sl?tis Markku Heli?vaara P?ivi Sainio Heikki Kinnunen Jyrki Kankare Nina Dalin-Hirvonen Seppo Seitsalo Arto Herno Pirkko Kortekangas Timo Niinim?ki Hannu R?nty Kaj Tallroth Veli Turunen Paul Knekt Tommi H?rk?nen Heikki Hurri | 2007 | Spine2007，，1： | 1 |
| 14 | Organizing Marketing in Industrial High-Tech Firms显示文摘 | Kristian Moller Arto Rajala | 1999 | Industrial Marketing Management1999，，28： | 1 |
| 15 | Different effects of pH on the permeation of pilocarpine and pilocarpine prodrugs across the isolated rabbit cornea显示文摘 | Pekka Suhonen Tomi J?rvinen Satu Koivisto Arto Urtti | 1998 | European Journal of Pharmaceutical Sciences1998，，3： | 1 |
| 16 | Narratives of Men's Experiences in Sport显示文摘 | Arja Laitinen Arto Tiihonen | 1990 | International Review for the Sociology of Sport1990，25，3： | 1 |
| 17 | Gastric outlet obstruction in gastric cancer: A comparison of three palliative methods显示文摘 | Ilona Ker?nen Leena Kyl?np?? Marianne Udd Johanna Louhimo Anna Lepist? Jorma Halttunen Arto Kokkola | 2013 | Oncol2013，，8： | 1 |
| 18 | Modeling of chromatographic sep- aration process with Wiener-MLP representation 显示文摘 | ARTO V HANNU P HALME A | 2001 | Journal of Pro- cess Control2001，11，5： | 1 |
| 19 | Transcatheter Embolization of a Renal Artery Aneurysm Using Ethylene Vinyl Alcohol Copolymer显示文摘 | Riitta Rautio Arto Haapanen | 2007 | CardioVascular and Interventional Radiology2007，，2： | 1 |
| 20 | Attrition of coal ash particles in a fluidized bed显示文摘 | Pis J J Fuertes A B Artos V | 1991 | Powder Technology1991，66，： | 1 |
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