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| 1 | Neo-adjuvant chemo(radio)therapy in gastric cancer: Current status and future perspectives显示文摘In the last 20 years, several clinical trials on neoadjuvant chemotherapy and chemo-radiotherapy as a therapeutic approach for locally advanced gastric cancer have been performed. Even if more data are necessary to define the roles of these approaches, the results of preoperative treatments in the combined treatment of gastric adenocarcinoma are encouraging because this approach has led to a higher rate of curative surgical resection. Owing to the results of most recent randomized phase III studies, neoadjuvant chemotherapy for locally advanced resectable gastric cancer has satisfied the determination of level I evidence. Remaining concerns pertain to the choice of the optimal therapy regimen, strict patient selection by accurate pre-operative staging, standardization of surgical procedures, and valid criteria for response evaluation. New well-designed trials will be necessary to find the best therapeutic approach in pre-operative settings and the best way to combine old-generation chemotherapeutic drugs with new-generation molecules. | Alberto Biondi Maria C Lirosi Domenico D'Ugo Valeria Fico Riccardo Ricci Francesco Santullo Antonia Rizzuto Ferdinando CM Cananzi Roberto Persiani | 2015 | World Journal of Gastrointestinal Oncology2015，7，12： | 13 |
| 2 | Percutaneous coronary intervention in nonagenarians: pros and cons显示文摘Percutaneous coronary intervention is a mainstay in the management of symptomatic or high-risk coronary artery disease. The bulk of clinical evidence and experience underlying this fact relies, however, on relatively young patients. Indeed, few data of very limited quality are available which adequately define the risk-benefit and cost-benefit profile of coronary angioplasty and stenting in very old subjects, such as those of 90 years of age or older (i.e., nonagenarians). The aim of this review is to provide a concise, yet practical, synthesis of the available evidence on percutaneous coronary revascularization in the very elderly. The main arguments elaborated upon are to what extent we can extrapolate findings from studies including younger patients to nonagenarians, whether we should provide higher priority to prognosis or quality of life in such patients, and whether we can afford to allocate vast resources to care for such subjects in an era of financial constraints. Our review of 18 studies and 1082 patients suggest that percutaneous coronary intervention is feasible and associated with acceptable short- and long-term results in this population, which is nonetheless fraught with a high mortality risk irrespective of the revascularization procedure. Accordingly, the pros and cons of percutaneous coronary intervention should be carefully weighed when considering this treatment in nonagenarians. | Giuseppe Biondi Zoccai Antonio Abbate Fabrizio D'Ascenzo Davide Presutti Mariangela Peruzzi Elena Cavarretta Antonino G.M. Marullo Marzia Lotrionte Giacomo Frati | 2013 | Journal of Geriatric Cardiology2013，10，1： | 6 |
| 3 | R0 resection in the treatment of gastric cancer:Room for improvement显示文摘Gastric carcinoma is one of the most frequent malignancies in the world and its clinical behavior especially depends on the metastatic potential of the tumor.In particular,lymphatic metastasis is one of the main predictors of tumor recurrence and survival,and current pathological staging systems reflect the concept that lymphatic spread is the most relevant prognostic factor in patients undergoing curative resection.This is compounded by the observation that two-thirds of gastric cancer in the Western world presents at an advanced stage,with lymph node metastasis at diagnosis.All current therapeutic efforts in gastric cancer are directed toward individualization of therapeutic protocols,tailoring the extent of resection and the administration of preoperative and postoperative treatment.The goals of all these strategies are to improve prognosis towards the achievement of a curative resection(R0 resection) with minimal morbidity and mortality,and better postoperative quality of life. | Alberto Biondi Roberto Persiani Ferdinando Cananzi Marco Zoccali Vincenzo Vigorita Andrea Tufo Domenico D'Ugo | 2010 | World Journal of Gastroenterology2010，16，27： | 4 |
| 4 | Preoperative chemotherapy in gastric cancer: expanding the indications, limiting the overuse显示文摘 | Ferdinando C. M. Cananzi Alberto Biondi Luca Cozzaglio Domenico D’Ugo Roberto Persiani Vittorio Quagliuolo | 2015 | Gastric Cancer2015，，1： | 2 |
| 5 | Response to neoadjuvant chemotherapy and effects of tumor regression in gastric cancer显示文摘 | D. D’Ugo R. Persiani S. Rausei A. Biondi V. Vigorita S. Boccia R. Ricci | 2006 | European Journal of Surgical Oncology2006，，10： | 2 |
| 6 | Preoperative treatment and surgery in gastric cancer: friends or foes?显示文摘 | Domenico D’Ugo Stefano Rausei Alberto Biondi Roberto Persiani | 2009 | Lancet Oncology2009，，2： | 2 |
| 7 | 卒中介入治疗培训指南:国际多学会共识文件显示文摘1背景
缺血性卒中是全球人口死亡和残疾的首要原因。很多急性大血管闭塞(emergent large vesselocclusion,ELVO)患者都会遗留长期残疾。事实上,这些颅内大动脉闭塞经常会导致大面积脑损伤,进而造成患者死亡或严重致残。 | Lavine SD Cockroft K Hoh B Bambakidis N Khalessi AA Woo H Riina H Siddiqui A Hirsch JA Chong W Rice H Wenderoth J Mitchell P Coulthard A Signh TJ Phatorous C Khangure M Klurfan P ter Brugge K Iancu D Gunnarsson T Pongpech S Rodesch G Soderman M Taylor A Krings T Orbach D Picard L Suh DC Zheng HQ Jansen O Muto M Szikora I Pierot L Brouwer P Gralla J Renowden S Andersson T Fiehler J Turjman F White P Januel AC Spelle L Kulcsar Z Chapot R Biondi A Dima S Taschner C Szajner M Krajina A Sakai N Matsumaru Y Yoshknura S Ezura M Fujinaka T Iihara K Ishii A Higashi T Hirohata M Hyodo A Ito Y Kawanishi M Kiyosue H Kobayashi E Kobayashi S Kuwayama N Matsumoto Y Miyachi S Murayama Y Nagata I Nakahara I Nemoto S Niimi Y Oishi H Satomi J Satow T Sugiu K Tanaka M Terada T Yamagami H Diaz O Lylyk P Jayaraman MV Patsalides A Gandhi CD Lee SK Abruzzo T Albani B Ansari SA Arthur AS Baxter BW Bulsara KR Chen M Almandoz JE Fraser JF Heck DV Hetts SW Hussain MS Klucznik RP Leslie-Mawzi TM Mack WJ McTaggart RA Meyers PM Mocco J Prestigiacomo CA Pride GL Rasmussen PA Starke RM Sunenshine PJ Tarr RW Frei DF Pabo M Nogueira RG Zaidat OO Jovin T Linfante I Yavagal D Liebeskind D Novakovic R Pongpech S 许岩 孙瑞 郭芮兵 | 2017 | 国际脑血管病杂志2017，25，5： | 2 |
| 8 | Wave-equation angle-domain common-image gathers for converted waves显示文摘 | Rosales D A Fomel S Biondi B L | 2008 | Geophysics2008，73，1： | 1 |
| 9 | Impact of mul - tives- sel stenting on top of percutaneous revascularization for unpro- tected left main disease in the drug - eluting stentera: insights from the Turin registry显示文摘 | Sheiban I Sillano D Biondi - Zoceai G | 2009 | J Cardiovasc Med2009，10，6： | 1 |
| 10 | Cervicogenic headaches:a review of diagnostic and treatment strategies显示文摘 | BIONDI D M | 2005 | J Am Osteopath Assoc2005，105，4： | 1 |
| 11 | A novel ketolide class: synthesis and antibacterial activity of a lead compound显示文摘 | Andreotti D Bientinesi I Biondi S | 2007 | Bioorg Med Chem Lett2007，17，18： | 1 |
| 12 | Long-term MR follow-up of cerebral lesions in neuro-Behcet's disease显示文摘 | GERBER S BIONDI A DORMONT D | 1996 | Neuroradiology1996，38，8： | 1 |
| 13 | Antioxidant activity of extracts of the marine algal genus,Cystoseira in amicel-lar model system显示文摘 | RUBERTO G BARATTA M T BIONDI D M | 2001 | Journal of Applied Phycology2001，13，5： | 1 |
| 14 | Subclinical thyroid disease显示文摘 | COOPER D S BIONDI B | 2012 | The Lancet2012，379，9821： | 1 |
| 15 | Constituents of stem and flower oils of Helichrysum litoreum Guss显示文摘 | RUBERTO G BIONDI D BARBAGALLO C | 2002 | Flavour Fragr J2002，17，1： | 1 |
| 16 | The clinical significance of subclinical thyroid dysfunction显示文摘 | BIONDI B COOPER D S | 2008 | Endocr Rev2008，29，1： | 1 |
| 17 | Relationship between volatile components of citrus fruit essential oils and antimicrobial action on Penicillium digitatum and Penicillium italicum显示文摘 | Caccioni D R L Guizzardi M Biondi D M Renda A Ruberto C | 1998 | Int J Food Microbiol1998，43，12： | 1 |
| 18 | Rela- tionship between volatile components of citrus fruit essential oils and antimicrobial action on Penicillium digitatum and Penicillium italicum 显示文摘 | Caccioni D R L Guizzardi M Biondi D M | 1998 | Int J Food Microbiol1998，43，12： | 1 |
| 19 | Cavernous sinus dural fistulae treated by transvenous approach through the facial vein:report of seven cases and review of the literature显示文摘 | Biondi A Milea D Cognard C | 2003 | Am J Neuroradiol2003，24，： | 1 |
| 20 | Antioxidant activity of extracts of the marine algal genus Cystoseira in a micellar model system显示文摘 | Ruberto G Baratta M T Biondi D M | 2001 | J Appl Phycol2001，13，： | 1 |
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