|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 羊膜培养液抑制角膜新生血管的实验研究显示文摘目的 研究羊膜培养液对小鼠角膜新生血管的抑制作用及机制。方法 应用cornealmicropocket方法 ,将含 10 0ng碱性成纤维细胞生长因子 (bFGF)和 12 %hydronpolymer的缓释颗粒植入角膜层间 ,制备小鼠角膜新生血管模型。实验分对照组、羊膜组和去上皮羊膜组 ,每组 10只眼 ,收集各组培养液于模型制作当日起 ,每日滴眼 4次至术后 7d摄片观测角膜新生血管长入情况并处死动物。对脐静脉血管内皮细胞 (HUVEC)进行体外培养 ,并应用Boyden小房技术和荧光结合(CyQUANT)实验分别检测羊膜培养液对HUVEC细胞迁移和细胞增殖的影响。利用酶联免疫吸附(ELISA)法检测各组培养液中金属蛋白酶抑制剂 1(TIMP1)和 2 (TIMP2 )的含量。结果 羊膜培养液明显抑制由bFGF诱发的小鼠角膜新生血管的形成 ,对照组、羊膜组和去上皮羊膜组角膜新生血管面积分别是 (2 4 8± 0 76 )mm2 、(0 6 4± 0 5 2 )mm2 和 (1 96± 0 6 5 )mm2 。羊膜培养液明显抑制血管内皮细胞的迁移和增殖 ,而对照组和去上皮羊膜组对HUVEC细胞迁移无作用。羊膜培养液中TIMP2水平明显增高 ,而TIMP1的含量无变化。结论 羊膜培养液中TIMP1的含量未增加。而羊膜上皮产生或释放大量的TIMP2 ,抑制血管内皮细胞的迁移和增殖 。 | 马翔 Haydee Bazan 李军 | 2003 | 中华眼科杂志2003，39，12： | 26 |
| 2 | 一种新型血小板激活因子受体拮抗剂预防碱烧伤引起的角膜基质溶解显示文摘目的:研究LAU0901(2,4,6-三甲基-1,4-二氢吡啶-3,5-二羧基酸酯),一种新型血小板激活因子受体拮抗剂,对严重碱烧伤兔眼角膜模型的作用。 | Jiucheng He Nicolas G. Bazan Haydee E. P. Bazan 王婷(译) | 2006 | 美国医学会眼科杂志(中文版)2006，18，4： | 10 |
| 3 | IL-33, an Interleukin-1-like Cytokine that Signals via the IL-1 Receptor-Related Protein ST2 and Induces T Helper Type 2-Associated Cytokines显示文摘 | Jochen Schmitz Alexander Owyang Elizabeth Oldham Yaoli Song Erin Murphy Terril K. McClanahan Gerard Zurawski Mehrdad Moshrefi Jinzhong Qin Xiaoxia Li Daniel M. Gorman J. Fernando Bazan Robert A. Kastelein | 2005 | Immunity2005，，5： | 6 |
| 4 | IL-33, an Interleukin-1-like Cytokine that Signals via the IL-1 Receptor-Related Protein ST2 and Induces T Helper Type 2-Associated Cytokines显示文摘 | Jochen Schmitz Alexander Owyang Elizabeth Oldham Yaoli Song Erin Murphy Terril K. McClanahan Gerard Zurawski Mehrdad Moshrefi Jinzhong Qin Xiaoxia Li Daniel M. Gorman J. Fernando Bazan Robert A. Kastelein | 2005 | Immunity2005，，5： | 3 |
| 5 | ECG Criteria to Identify Epicardial Ventricular Tachycardia in Nonischemic Cardiomyopathy显示文摘 | Ermengol Vallès Victor Bazan Francis E. Marchlinski | 2010 | Circulation: Arrhythmia and Electrophysiology2010，，1： | 2 |
| 6 | Secretory phospholipase A(2) induces delayed neuronal COX-2 expression compared with glutamate显示文摘 | Kolko M Nielsen M Bazan NG | 2002 | J Neurosci Res2002，69，2： | 2 |
| 7 | PI3K/Akt and mTOR/p70S6K pathways mediate neuroprotectin D1-induced retinal pigment epithelial cell survival during oxidative stress-induced apoptosis显示文摘 | Zahra Faghiri Nicolas G. Bazan | 2010 | Experimental Eye Research2010，，6： | 2 |
| 8 | The CD40 antigen and its ligand 显示文摘 | Banchereau J Bazan F Blanchard D | 1994 | Annu Rev Immunol1994，12，： | 2 |
| 9 | Electrophosphorescence from a conjugated copolymer doped with an iridium complex: high brightness andimproved operational stability显示文摘 | Gong X Ostrowski J C Bazan G C | 2003 | Advanced Materials2003，15，1： | 1 |
| 10 | Asteroid Bodies in a Patient with oil Breast Implants显示文摘 | MaLasso J Toledo GI Bazan A | 2001 | Plast Reconstr Surg2001，108，： | 1 |
| 11 | A new class of mere-brane-bound chemokine with a CX3C motif显示文摘 | Bazan JF Bacoon KB Hardiman G | 1997 | Nature1997，385，： | 1 |
| 12 | Specific codon 13 K- ras mutations are predictive of clinical outcome in eolorectal cancer patients, whereas eodon 12 K-ras mutations are associated with mucinous histotype 显示文摘 | Bazan V Migliavaeea M Zanna I | 2002 | Ann Oneol2002，13，： | 1 |
| 13 | Isolation, characteriza- tion and chromosomal localization of human WNT10B 显示文摘 | Hardiman G Kastelein RA Bazan JF | 1997 | Cytogenet Cell Genet1997，77，34： | 1 |
| 14 | c-Jun N-terminal kinase activation responses induced by hippocampal kindling are mediated by reactive astrocytes显示文摘 | Cole-Edwards KK Musto AE Bazan NG | 2006 | J Neurosci2006，26，： | 1 |
| 15 | Corned stimulation of MMP21,29 and uPA by platelet-activation factor is mediated by cyclooxygenase-2 metabolites显示文摘 | Ottino P Bazan H E | 2001 | Curr Eye Bes2001，23，2： | 1 |
| 16 | Autosomal SCID caused by a point mutation in the N-terminus of JAK3 : mapping of the Jak3-reeeptor interaction domain 显示文摘 | Cacalano b/A Migone TS Bazan F | 1999 | EMBO J1999，18，： | 1 |
| 17 | Post critical imperfection sensitivity of sandwich or homogenized orthotropic columns soft in shear and in transverse deformation 显示文摘 | BAZAN B | 2006 | International Journal of Solids and Structures2006，43，18： | 1 |
| 18 | Mediator ofinjury in neurotrauma : intracellular signal transduction andgene expression显示文摘 | Bazan N G Rodriguez de Turco E B Allan G | 1995 | J Neurotrauma1995，12，5： | 1 |
| 19 | DNA aneuploidy and high proliferative activity but not K-ras-2 mutations as independent predictors of clinical outcome in operable gastric carcinoma: results of a 5-year Group Oncologico dell' Italia Meridonale (GDIM) prospective study显示文摘 | Bazan V Migliavacca M | 2001 | Cancer2001，92，： | 1 |
| 20 | Specific codon 13 K-ras muta- tions are predictive of clinical outcome in eolorectal cancer patients, whereas cedon 12 K-ras mutations are associated with mucinous pheno- type显示文摘 | Bazan V Migliavacca M Zatma 1 | 2002 | Ann Oncol2002，13，9： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员