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| 1 | Standard triple therapy for Helicobacter pylori infection in China: A meta-analysis显示文摘AIM:To assess the efficacy and safety of standard triple therapy compared with other pre-existing and new therapies in China.METHODS:Literature searches were conducted in the following databases:PubMed,EMBASE,the Cochrane Central Register of Controlled Trials,the VIP database,the China National Knowledge Infrastructure database,and the Chinese Biomedical Database.A meta-analysis of all randomized controlled trials(RCTs)comparing standard triple therapy for the eradication of Helicobacter pylori with pre-existing and new therapies in China was performed using Comprehensive Meta-Analysis 2.0.There were 49 studies that met our criteria and the qualities of these studies were assessed using the Jadad scale.The Mantel-Haenszel method was used for pooling dichotomous data.We also conducted subgroupanalyses according to age,duration of treatment and drug type.Sensitivity analyses and a cumulative metaanalysis were also performed with CMA 2.0.Publication bias was evaluated using Egger’s test,Begg’s test or a funnel plot.RESULTS:A total of 49 RCTs including 8332 patients were assessed.This meta-analysis showed that standard triple therapy with proton pump inhibitors(PPIs),amoxicillin(AMO)and clarithromycin(CLA)was inferior to sequential therapy[relative risk(RR)=0.863;95%confidence interval(CI):0.824-0.904],but was not superior to quadruple therapy(RR=1.073;95%CI:0.849-1.357)or other triple therapies(RR=1.01;95%CI:0.936-1.089).The meta-analysis also suggested that standard triple therapy is slightly more effective than dual therapy(RR=1.14;95%CI:0.99-1.31).However,the differences were not statistically significant.We removed the only trial with a regimen lasting14 d by sensitivity analysis and found that 7-d standard triple therapy was superior to 7-d dual therapy(RR=1.222;95%CI:1.021-1.461).Moreover,a sub-analysis based on the duration of quadruple therapy indicated that the 7-d and 10-d standard triple therapies were inferior to sequential therapy(RR=0.790;95%CI:0.718-0.868;RR=0.917;95%CI:0.839-1.002,respectively).Additionally,there were no significant differences in cure rate or adverse events among standard triple therapy,quadruple therapy,and other triple therapies(RR=0.940;95%CI:0.825-1.072;RR=1.081;95%CI:0.848-1.378,respectively).Standard triple therapy had a higher occurrence of side effects than sequential therapy(RR=1.283;95%CI:1.066-1.544).CONCLUSION:The eradication rates with a standard triple therapy consisting of PPI,AMO,and CLA are suboptimal in China,and new treatment agents need to be developed. | Ben Wang Zhi-Fa Lv You-Hua Wang Hui Wang Xiao-Qun Liu Yong Xie Xiao-Jiang Zhou | 2014 | World Journal of Gastroenterology2014，20，40： | 46 |
| 2 | Effect of local wound infiltration with ropivacaine on postoperative pain relief and stress response reduction after open hepatectomy显示文摘AIM To prospectively evaluate the effect of local wound infiltration with ropivacaine on postoperative pain relief and stress response reduction after open hepatectomy.METHODS A total of 56 patients undergoing open hepatectomy were randomly divided into two groups:a ropivacaine group(wound infiltration with ropivacaine solution)and a control group(infiltration with isotonic saline solution).A visual analog scale(VAS)at rest and on movement was used to measure postoperative pain for the first 48 h after surgery.Mean arterial pressure(MAP),heart rate(HR),time to bowel recovery,length of hospitalization after surgery,cumulative sufentanil consumption,and incidence of nausea and vomiting were compared between the two groups.Surgical stress hormones(epinephrine,norepinephrine,and cortisol)were detected using enzyme-linked immunosorbent assay,and the results were compared. RESULTS VAS scores both at rest and on movement at 24 h and48 h were similar between the two groups.Significantly lower VAS scores were detected at 0,6,and 12 h in the ropivacaine group compared with the control group(P<0.05 for all).MAP was significantly lower at 6,12,and 24 h(P<0.05 for all);HR was significantly lower at 0,6,12,and 24 h(P<0.05 for all);time to bowel recovery and length of hospitalization after surgery(P<0.05 for both)were significantly shortened;and cumulative sufentanil consumption was significantly lower at 6,12,24,and 36 h(P<0.05 for all)in the ropivacaine group than in the control group,although the incidence of nausea and vomiting showed no significant difference between the two groups.The levels of epinephrine,norepinephrine,and cortisol were significantly lower in the ropivacaine group than in the control group at 24 and 48 h(P<0.01 for all). CONCLUSION Local wound infiltration with ropivacaine after open hepatectomy can improve postoperative pain relief,reduce surgical stress response,and accelerate postoperative recovery. | Jing-Xian Sun Ke-Yun Bai Yan-Feng Liu Gang Du Zhi-Hao Fu Hao Zhang Jin-Huan Yang Ben Wang Xiu-Yu Wang Bin Jin | 2017 | World Journal of Gastroenterology2017，23，36： | 25 |
| 3 | Regulation of HMGB1 release by infl ammasomes显示文摘High mobility group box 1(HMGB1)is an evolutionarily conserved non-histone chromatin-binding protein.During infection or injury,activated immune cells and damaged cells release HMGB1 into the extracellular space,where HMGB1 functions as a proinflammatory mediator and contributes importantly to the pathogenesis of inflammatory diseases.Recent studies reveal that infl ammasomes,intracellular protein complexes,critically regulate HMGB1 release from activated immune cells in response to a variety of exogenous and endogenous danger signals.Double stranded RNA dependent kinase(PKR),an intracellular danger-sensing molecule,physically interacts with inflammasome components and is important for infl ammasome activation and HMGB1 release.Together,these studies not only unravel novel mechanisms of HMGB1 release during infl ammation,but also provide potential therapeutic targets to treat HMGB1-related infl ammatory diseases. | Ben Lu Haichao Wang Ulf Andersson Kevin J.Tracey | 2013 | Protein & Cell2013，4，3： | 21 |
| 4 | An alternative therapy for drug-resistant epilepsy: transcutaneous auricular vagus nerve stimulation显示文摘 | Rong Peijing Liu Aihua Zhang Jianguo Wang Yuping Yang Anchao Li Liang Ben Hui Li Liping Liu Rupeng He Wei Liu Huanguang Huang Feng Li Xia Wu Peng Zhu Bing | 2014 | Chinese Medical Journal2014，，2： | 20 |
| 5 | An insight into the removal of fluoroquinolones in activated sludge process:Sorption and biodegradation characteristics显示文摘The detailed sorption steps and biodegradation characteristics of fluoroquinolones(FQs)including ciprofloxacin, enrofloxacin, lomefloxacin, norfloxacin, and ofloxacin were investigated through batch experiments. The results indicate that FQs at a total concentration of 500 μg/L caused little inhibition of sludge bioactivity. Sorption was the primary removal pathway of FQs in the activated sludge process, followed by biodegradation, while hydrolysis and volatilization were negligible. FQ sorption on activated sludge was a reversible process governed by surface reaction. Henry and Freundlich models could describe the FQ sorption isotherms well in the concentration range of 100–300 μg/L. Thermodynamic parameters revealed that FQ sorption on activated sludge is spontaneous, exothermic, and enthalpy-driven. Hydrophobicity-independent mechanisms determined the FQ sorption affinity with activated sludge. The zwitterion of FQs had the strongest sorption affinity, followed by cation and anion, and aerobic condition facilitated FQ sorption. FQs were slowly biodegradable, with long half-lives(> 100 hr). FQ biodegradation was enhanced with increasing temperature and under aerobic condition,and thus was possibly achieved through co-metabolism during nitrification. This study provides an insight into the removal kinetics and mechanism of FQs in the activated sludge process, but also helps assess the environmental risks of FQs resulting from sludge disposal. | Lu Wang Zhimin Qiang Yangang Li Weiwei Ben | 2017 | Journal of Environmental Sciences2017，29，6： | 18 |
| 6 | Meta-analysis:Is combination of tetracycline and amoxicillin suitable for Helicobacter pylori infection?显示文摘AIM:To access the efficacy of combination with amoxicillin and tetracycline for eradication of Helicobacter pylori(H.pylori),thus providing clinical practice guidelines.METHODS:Pub Med,EMBASE,Cochrane Central Register of Controlled Trials,Science Citation Index,China National Knowledge Infrastructure,Wanfang,and Chinese Biomedical Literature databases and abstract books of major European,American,and Asian gastroenterological meetings were searched.All clinical trials that examined the efficacy of H.pylori eradication therapies and included both tetracycline and amoxicillin in one study arm were selected for this systematic review and meta-analysis.Statistical analysis was performed with Comprehensive Meta-Analysis Software(Version 2).Subgroup,meta-regression,and sensitivity analyses were also carried out.RESULTS:Thirty-three studies met the inclusion criteria.The pooled odds ratio(OR)was 0.90(95%CI:0.42-1.78)for quadruple therapy with amoxicillin and tetracycline vs other quadruple regimens,and total eradication rates were 78.1%by intention-to-treat(ITT)and 84.5%by per-protocol(PP)analyses in the experimental groups.The pooled eradication rates of 14-d quadruple regimens with a combination of amoxicillin and tetracycline were 82.3%by ITT and89.0%by PP,and those of 10-d regimens were 84.6%by ITT and 93.7%by PP.The OR by ITT were 1.21(95%CI:0.64-2.28)for triple regimens with amoxicillin and tetracycline vs other regimens and 1.81(95%CI:1.37-2.41)for sequential treatment with amoxicillin and tetracycline vs other regimens,respectively.CONCLUSION:The effectiveness of regimens employing amoxicillin and tetracycline for H.pylori eradication may be not inferior to other regimens,but further study should be necessary. | Zhi-Fa Lv Fu-Cai Wang Hui-Lie Zheng Ben Wang Yong Xie Xiao-Jiang Zhou Nong-Hua Lv | 2015 | World Journal of Gastroenterology2015，21，8： | 17 |
| 7 | Predictors to assess non-sentinel lymph node status in breast cancer patients with only one sentinel lymph node metastasis显示文摘 | YANG Ben YANG Li ZUO Wen-shu GE Wen-kai ZHENG Gang ZHENG Mei-zhu YU Zhi-yong WANG Yong-sheng | 2013 | Chinese Medical Journal2013，，3： | 17 |
| 8 | Accelerometer-based Chinese Traffic Police Gesture Recognition System显示文摘 | YUAN Tao WANG Ben | 2010 | Chinese Journal of Electronics2010，19，2： | 14 |
| 9 | Extracellular vesicles from human urine-derived stem cells prevent osteoporosis by transferring CTHRC1 and OPG显示文摘Osteoporosis is a debilitating bone disease affecting millions of people. Here, we used human urine-derived stem cells(USCs),which were noninvasively harvested from unlimited and easily available urine, as a 'factory' to obtain extracellular vesicles(USCEVs) and demonstrated that the systemic injection of USC-EVs effectively alleviates bone loss and maintains bone strength in osteoporotic mice by enhancing osteoblastic bone formation and suppressing osteoclastic bone resorption. More importantly, the anti-osteoporotic properties of USC-EVs are not notably disrupted by the age, gender, or health condition(with or without osteoporosis) of the USC donor. Mechanistic studies determined that collagen triple-helix repeat containing 1(CTHRC1) and osteoprotegerin(OPG) proteins are enriched in USC-EVs and required for USC-EV-induced pro-osteogenic and anti-osteoclastic effects. Our results suggest that autologous USC-EVs represent a promising novel therapeutic agent for osteoporosis by promoting osteogenesis and inhibiting osteoclastogenesis by transferring CTHRC1 and OPG. | Chun-Yuan Chen Shan-Shan Rao Yi-Juan Tan Ming-Jie Luo Xiong-Ke Hu Hao Yin Jie Huang Yin Hu Zhong-Wei Luo Zheng-Zhao Liu Zhen-Xing Wang Jia Cao Yi-Wei Liu Hong-Ming Li Yang Chen Wei Du Jiang-Hua Liu Yan Zhang Tuan-Hui Chen Hao-Ming Liu Ben Wu Tao Yue Yi-Yi Wang Kun Xia Peng-Fei Lei Si-Yuan Tang Hui Xie | 2019 | Bone Research2019，7，3： | 14 |
| 10 | The Change of the Inlet Geometry of a Centrifugal Compressor Stage and its Influence on the Compressor Performance显示文摘The impact on the compressor performance is important for designing the inlet pipe of the centrifugal compressor of a vehicle turbocharger with different inlet pipes. First, an experiment was performed to determine the compressor performance from three cases: a straight inlet pipe, a long bent inlet pipe and a short bent inlet pipe. Next, dynamic sensors were installed in key positions to collect the sign of the unsteady pressure of the centrifugal compressor. Combined with the results of numerical simulations, the total pressure distortion in the pipes, the pressure distributions on the blades and the pressure variability in the diffuser are studied in detail. The results can be summarized as follows: a bent pipe results in an inlet distortion to the compressor, which leads to performance degradation, and the effect is more apparent as the mass flow rate increases. The distortion induced by the bent inlet is not only influenced by the distance between the outlet of the bent section and the leading edge of the impeller but also by the impeller rotation. The flow fields in the centrifugal impeller and the diffuser are influenced by a coupling effect produced by the upstream inlet distortion and the downstream blocking effect from the volute tongue. If the inlet geometry is changed, the distributions and the fluctuation intensities of the static pressure on the main blade surface of the centrifugal impeller and in the diffuser are changed accordingly. | WANG Leilei YANG Ce ZHAO Ben LAO Dazhong MA Chaochen LI Du | 2013 | Journal of Thermal Science2013，22，3： | 13 |
| 11 | Evaluation of the Prostate Imaging Reporting and Data System for Magnetic Resonance Imaging Diagnosis of Prostate Cancer in Patients with Prostate-specific Antigen 〈20 ng/ml显示文摘 | Xuan Wang Jian-Ye Wang Chun-Mei Li Ya-Qun Zhang Jian-Long Wang Ben Wan Wei Zhang Min Chen Sa-Ying Li Gang Wan Ming Liu | 2016 | Chinese Medical Journal2016，，12： | 13 |
| 12 | 2018 update of expert consensus statement on antiplatelet therapy in East Asian patients with ACS or undergoing PCI显示文摘East Asians are the most populous race in the world and their health status is an important global issue.Compared with Caucasian populations, East Asian patients have a different benefit/risk ratio when using antithrombotic treatment. Despite this observation, treatment strategies in East Asian patients are mostly based on the American and European guidelines. Despite a lower platelet inhibitory response to clopidogrel, East Asian patients show a similar or even a lower rate of ischemic event occurrence and higher bleeding risk compared with Caucasian patients. For potent P2Y_(12) inhibitors(ticagrelor and prasugrel),East Asian patients have shown less favorable net clinical benefits compared with Caucasian patients,which may be related to differences in pharmacokinetic/pharmacodynamic profiles and therapeutic zone of antiplatelet effect. This updated consensus mainly focuses on state-of-the-art and current controversies in the East Asian population. In addition, when East Asian patients are administered potent P2Y_(12) receptor inhibitors, the strategies and ongoing trials to overcome the related hurdles are discussed. | Yong Huo Young-Hoon Jeong Yanjun Gong Daowen Wang Ben He Jiyan Chen Guosheng Fu Yundai Chen Jianping Li Yi Li Shinya Goto Udaya S.Tantry Paul A.Gurbel Jong-Hwa Ahn Hyo-Soo Kim Myung Ho Jeong Yaling Han Sidney C.Smith Jr. Junbo Ge | 2019 | Science Bulletin2019，64，3： | 12 |
| 13 | A general theoretical principle for single-phase convection heat transfer enhancement显示文摘The main methods of single-phase convection heat transfer enhancement are analyzed in this paper, and the unity of contradiction between heat transfer enhancement and energy consumption(or exergy destruction)is expounded.The thermodynamic relationship between heat(or exergy)transfer efficiency and energy consumption(or exergy destruction)as well as driving forces is established,and a general theoretical principle for single-phase convection heat transfer enhancement is further obtained. The principle shows that temperature gradient field distribution and velocity field distribution constrain each other,and that the optimum heat transfer efficiency can be obtained when they are synergetic.If the level of the synergy of temperature gradient field distribution with velocity field distribution is determined,the relative uniform temperature gradient is required,and vice versa.The principle also shows the relationship of relative temperature gradient with specific heat and coefficient of heat conductivity.The deduced results can be used as a theoretical guidance for single-phase convection heat transfer enhancement and optimum design of heat exchangers. | WANG SongPing CHEN QingLin ZHANG BingJian HUA Ben | 2009 | Science China(Technological Sciences)2009，52，12： | 12 |
| 14 | Adsorptive removal of antibiotics from water using magneticion exchange resin显示文摘The occurrence of antibiotics in the environment has recently raised serious concern regarding their potential threat to aquatic ecosystem and human health. In this study, the magnetic ion exchange(MIEX) resin was applied for removing three commonly-used antibiotics, sulfamethoxazole(SMX), tetracycline(TCN) and amoxicillin(AMX) from water.The results of batch experiments show that the maximum adsorption capacities on the MIEX resin for SMX, TCN and AMX were 789.32, 443.18 and 155.15 μg/m L at 25°C,respectively, which were 2–7 times that for the powdered activated carbon. The adsorption kinetics of antibiotics on the MIEX resin could be simulated by the pseudo-second-order model(R^2= 0.99), and the adsorption isotherm data were well described by the Langmuir model(R^2= 0.97). Solution p H exhibited a remarkable impact on the adsorption process and the absorbed concentrations of the tested antibiotics were obtained around the neutral p H.The MIEX resin could be easily regenerated by 2 mol/L Na Cl solution and maintained high adsorption removal for the tested antibiotics after regeneration. Anion exchange mechanism mainly controlled the adsorption of antibiotic and the formation of hydrogen binding between the antibiotic and resin can also result in the increase of adsorption capacity. The high adsorption capacity, fast adsorption rate and prominent reusability make the MIEX resin a potential adsorbent in the application for removing antibiotics from water. | Tianyue Wang Xun Pan Weiwei Ben Jianbing Wang Pin Hou Zhimin Qiang | 2017 | Journal of Environmental Sciences2017，29，2： | 12 |
| 15 | Absence of gender disparity in short-term clinical outcomes in patients with acute ST-segment elevation myocardial infarction undergoing irolimus-eluting stent based primary coronary intervention: a report from Shanghai Acute Coronary Event (SACE) Registry显示文摘背景使随机化的、控制试用表明了 sirolimus-eluting stent (SES ) 的优势培植在主要经皮的冠的干预(一种总线标准) 期间与赤裸金属的 stents 对比,在有圣举起心肌的梗塞(STEMI ) 的病人。这研究试图测试 SES 治疗的临床的好处独立于在这 setting.Methods 的性的假设有经历基于 SES 的主要一种总线标准的 STEMI 的 2042 个病人的一个总数有希望地被注册进上海尖锐冠的事件(SACE ) 登记(1574 个男人和 468 个女人) 。基线人口分布, angiographic 和一种总线标准特征,和在里面医院和 30 天的主要不利心脏的事件(向) 作为性的功能被分析。与男人相比结果,女人们是更旧、更经常有的高血压,糖尿病,和血胆脂醇过多。血小板 glycoprotein IIb/IIIa 受体禁止者的使用(GPI, 65.5% 对 62.2% , P=0.10 ) 并且程序的成功率(95.0% 对 94.2% , P=0.52 ) 在两性是类似的。在里面医院死亡和向发生了在 3.8% 和 7.6% ,和 4.5% 和 8.1% 在男、女的病人,分别地(所有 P > 0.05 ) 。在 30 天的后续,幸存(94.3% 对 93.8% , P=0.66 ) 并且没有向的幸存(90.2% 对 89.3% , P=0.52 ) 显著地没在男人和女人之间不同。在为在耐心的人口分布, angiographic 和 proceduralfeatures 的差别的调整以后,在任何一个在里面医院没有重要差别( OR=0.77 , 0.48~1.22 的95%C/, P=0.30 )或30天的死亡( OR=1.28 , 0.73~2.23 的95%C/, P=0.38 )在尽管有更先进的年龄的女人和 men.Conclusion 之间并且在女人风险因素聚类,有 基于SES 的主要一种总线标准对待的 STEMI 的女病人作为他们的男对应物有类似的在里面医院和短期的临床的结果。 | ZHANG Qi QIU Jian-ping ZHANG Rui-yan LI Yi-gang HE Ben JIN Hui-gen ZHANG Jun-feng WANG Xiao-long JIANG Li LIAO Min-lei HU Jian SHEN Wei-feng | 2010 | Chinese Medical Journal2010，，7： | 10 |
| 16 | The Future of Manufacturing: A New Perspective显示文摘关于智能制造,前人已发表了很多文章。其大多数内容都集中在硬件、软件、增材制造、机器人、物联网(Internet of Thing,IoT)以及工业4.0等话题,而对另一些极重要的领域却少有讨论,如混合系统、先进制造业重定义、新制造的基本构成元素、制造业生态系统准备水平及技术可扩展性等。本文将通过实例,从全新的视角,为读者剖析这些领域中目前的四个挑战。挑战一:当我们希望提高公众对新制造业经济及其社会影响的认识水平,并获得政策制定者的明确支持时,应如何重新定义未来制造业。挑战二:如何正确认识到未来制造业的关键词是'混合'。它具有人类与机器人协作、增材制造与减材制造结合、金属材料与复合材料并用以及网络系统与物理系统融合等特点。因此,划定界限与制定标准变得尤其重要。挑战三:如何开发一个同时对技术、制造商业化和新制造生态系统做出评估的通用框架,以缩短生产到交付之间的时间;以及在该框架下,如何进一步制定一套可被广泛采用的、针对非信息技术的可扩增性测量的标准。最后,也是同样重要的是挑战四:如何通过公司多方合作,来验证'产-学-政'三位一体的模型是否成功。本文将详细讨论上述四大挑战。 | Ben Wang | 2018 | Engineering2018，4，5： | 9 |
| 17 | A Review on the 3D Printing of Functional Structures for Medical Phantoms and Regenerated Tissue and Organ Applications显示文摘医学模型或模具已广泛应用于医学培训和医患互动领域,同时也日益应用于手术规划、医学计算模型、算法核实和验证以及医疗器械的开发等方面。这种新应用需要高保真度、患者特异性及模拟组织结构的医学模具,其不仅能够模拟人体器官的几何结构,而且还具有器官的功能。随着三维(3D)打印和3D生物打印技术的快速发展,许多研究人员已经开始使用增材制造技术来生产具有多种功能的医学模具。本文综述了3D打印和3D生物打印技术在制作功能性医学模具和生物结构方面的应用。特别讨论了3D打印功能性医学模具(即组织模拟医学模具、放射性医学模具和生理医学模具)及被用于再生组织和器官的3D生物打印模具的制备(即混合模式支架材料、可转换支架和集成传感器)工艺、发展现状以及未来发展趋势。 | Kan Wang Chia-Che Ho Chuck Zhang Ben Wang | 2017 | Engineering2017，3，5： | 9 |
| 18 | The Impacts of Urbanization on the Distribution and Body Condition of the Rice-paddy Frog(Fejervarya multistriata) and Gold-striped Pond Frog(Pelophylax plancyi) in Shanghai,China显示文摘Previous studies have suggested that urbanization presents a major threat to anuran populations. However, very few studies have looked at the relationship between urbanization and anuran body condition. We investigated whether the distribution and body condition of the rice-paddy frog(Fejervarya multistriata) and gold-striped pond frog(Pelophylax plancyi) are influenced by increasing urbanization in Shanghai, China. Four study sites with six indicators of the major land-cover types were scored to indicate their position on an urbanization gradient. We found that both the density and body condition of F. multistriata declined significantly along this gradient. Although we observed a significant difference in body condition of P. plancyi among study sites with different degrees of urbanization, we did not find any corresponding significant differences in population density. Our results indicate that both the densities and body condition of these two anuran species show a negative relationship with increasing urbanization, but that the density of P. plancyi was only slightly affected in Shanghai. | Ben LI Wei ZHANG Xiaoxiao SHU Enle PEI Xiao YUAN Yujie SUN Tianhou WANG Zhenghuan WANG | 2016 | Asian Herpetological Research2016，7，3： | 9 |
| 19 | Preparation of Cationic Chitosan-Polyacrylamide Flocculant and Its Properties in Wastewater Treatment显示文摘Chitosan derived from crab shells,was used to prepare the graft polymer in aqueous solution with acrylamide (AM) and methacrylatoethyl trimethyl ammonium chloride (DMC) as raw materials and ceric ammonium nitrate (CAN) as initiator.The floc-culation ability of the resulting polymer (PCAD) was studied in waste water treatment experiments.Its properties were determined on the basis of the transmittance of waste water after flocculation.The effects of chitosan and DMC content on PCAD’s flocculation ability were studied.Flocculation experiments were also undertaken under various pH conditions.According to the experimental data,the flocculation ability could be improved when chitosan content decreased in the raw material,but the monomer conversion would decrease obviously.When the chitosan’s content was more than 65%,AM and DMC groups were less on each chitosan molecule.So PCAD’s flocculation ability was poor.Similarly,high content of DMC would result in low monomer conversion and high floccula-tion ability.PCAD molecules with more DMC group had more positive charges.It was favorable to flocculation.However,monomer conversion would decrease with the increase of DMC content.The suitable conditions were that chitosan and DMC contents were 65% and 15-20%,respectively.The experiment data showed that PCAD had good flocculation ability under weak acidic condition.Its ability would be weakened by strong acidic or alkaline condition.The flocculation efficiency was the best at pH of 5.5 when PCAD’s dosage was 8mg?L-1.Compared with cationic polymer (the copolymer of AM and DMC,PAD),PCAD showed better floc-culation ability under acid and neutral conditions,but worse ability under alkaline condition. | WANG Ben ZHANG Yulian MIAO Chunbao | 2011 | Journal of Ocean University of China2011，10，1： | 9 |
| 20 | Nine-month angiographic and two-year clinical follow-up of polymer-free sirolimus-eluting stent versus durable-polymer sirolimus-eluting stent for coronary artery disease: the Nano randomized trial显示文摘 | Zhang Yaojun Chen Fang Takashi Muramatsu Xu Bo Li Zhanquan Ge Junbo He Qing Yang Zhijian Li Shumei Wang Lefeng Wang Haichang He Ben Li Kang Qi Guoxian Li Tianchang Zeng Hesong Peng Jianjun Jiang Tieming Zeng Qiutang Zhu Jianhua Fu Guosheng Christos V. Bourantas Patrick W. Serruys Huo Yong | 2014 | Chinese Medical Journal2014，，11： | 8 |
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