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| 1 | Cardiac autonomic nerve fiber regeneration in chronic heart failure Do Akt gene-transduced mesenchymal stem cells promote repair?显示文摘BACKGROUND: Transplantation of Akt-over-expressing mesenchymal stem cells (Akt-MSCs) has been shown to repair infarcted myocardium and improve cardiac function. However, little is known about the therapeutic effects of Akt-MSCs on cardiac autonomic neuropathy in chronic heart failure (CHF). OBJECTIVE: The present study used adriamycin-induced CHF rat models to observe the effect of Akt-MSCs on cardiac autonomic nervous regeneration and the factors mediating this effect. DESIGN, TIME AND SETTING: A randomized, controlled animal experiment was performed at the Central Laboratory of Basic Medical College, China Medical University, between September 2008 and April 2009. MATERIALS: Rabbit anti-choline acetyltransferase (ChAT), growth associated protein-43 (GAP-43), synaptophysin (SYN) polyclonal antibodies and the secondary antibody (goat anti-rabbit IgG) were purchased from Boster, China. Cat-A-Kit assay system was provided by Amersham, USA. METHODS: (1) Adult rat MSCs were isolated and cultured for the preparation of Akt-MSCs. (2) Forty male Wistar rats were intramyocardially administered adriamycin at 2 mg/kg over 3 days for a total of five times and once a week for additional five times thereafter to establish CHF models. At 2 weeks after final adriamycin treatment, 34 successful CHF rat models were randomized to three groups: Akt-MSCs (n = 11), simple MSCs (s-MSCs, n =11), and control (n = 12). Each group was intravenously administered Akt-MSCs (2×106 cells in 100 μL PBS), s-MSCs (2×106 cells in 100 μL PBS) or equal volume of phosphate buffered saline, once a day for a total of three times. MAIN OUTCOME MEASURES: At 4 weeks after final adriamycin treatment, myocardial norepi- nephrine (NE) content was detected using a Cat-A-Kit assay system. Myocardial ChAT, SYN and GAP-43 were performed by immunohistochemistry and Western blot analysis. Prior to, 2 and 4 weeks after adriamycin treatment, echocardiographic examination was performed and left ventricular ejection fraction (LVEF) was determined. RESULTS: Myocardial NE content, as well as SYN-positive and GAP-43-positive nerve fiber density and expression, and LVEF, was the greatest in the Akt-MSCs group, followed by the s-MSCs group, and lastly the control group (P < 0.05 or P < 0.01). ChAT expression was similar between Akt-MSCs and s-MSCs groups, but it was higher compared with the control group (P < 0.05). NE contents were negatively correlated to LVEF (r = -0.64, P = 0.015). CONCLUSION: Transplantation of MSCs, in particular Akt-MSCs, promotes cardiac nervous regeneration in failing heart, which might be mediated by GAP-43. | Hongliang Kong Zhanquan Li Shumei Zhao Li Zhu Yingjun Zhao Weiwei Zhang GuipingXu Wenjun Hao Huijun Li Guoxian Qi | 2010 | Neural Regeneration Research2010，5，1： | 13 |
| 2 | Insight-HXMT observations of the first binary neutron star merger GW170817显示文摘Finding the electromagnetic(EM) counterpart of binary compact star merger, especially the binary neutron star(BNS) merger,is critically important for gravitational wave(GW) astronomy, cosmology and fundamental physics. On Aug. 17, 2017,Advanced LIGO and Fermi/GBM independently triggered the first BNS merger, GW170817, and its high energy EM counterpart,GRB 170817 A, respectively, resulting in a global observation campaign covering gamma-ray, X-ray, UV, optical, IR, radio as well as neutrinos. The High Energy X-ray telescope(HE) onboard Insight-HXMT(Hard X-ray Modulation Telescope) is the unique high-energy gamma-ray telescope that monitored the entire GW localization area and especially the optical counterpart(SSS17 a/AT2017 gfo) with very large collection area(~1000 cm^2) and microsecond time resolution in 0.2-5 MeV. In addition,Insight-HXMT quickly implemented a Target of Opportunity(ToO) observation to scan the GW localization area for potential X-ray emission from the GW source. Although Insight-HXMT did not detect any significant high energy(0.2-5 MeV) radiation from GW170817, its observation helped to confirm the unexpected weak and soft nature of GRB 170817 A. Meanwhile,Insight-HXMT/HE provides one of the most stringent constraints(~10^(-7) to 10^(-6) erg/cm^2/s) for both GRB170817 A and any other possible precursor or extended emissions in 0.2-5 MeV, which help us to better understand the properties of EM radiation from this BNS merger. Therefore the observation of Insight-HXMT constitutes an important chapter in the full context of multi-wavelength and multi-messenger observation of this historical GW event. | TiPei Li ShaoLin Xiong ShuangNan Zhang FangJun Lu LiMing Song XueLei Cao Zhi Chang Gang Chen Li Chen TianXiang Chen Yong Chen YiBao Chen YuPeng Chen Wei Cui WeiWei Cui JingKang Deng YongWei Dong YuanYuan Du MinXue Fu GuanHua Gao He Gao Min Gao MingYu Ge YuDong Gu Ju Guan ChengCheng Guo DaWei Han Wei Hu Yue Huang Jia Huo ShuMei Jia LuHua Jiang WeiChun Jiang Jing Jin YongJie Jin Bing Li ChengKui Li Gang Li MaoShun Li Wei Li Xian Li XiaoBo Li XuFang Li YanGuo Li ZiJian Li ZhengWei Li XiaoHua Liang JinYuan Liao CongZhan Liu GuoQing Liu HongWei Liu ShaoZhen Liu XiaoJing Liu Yuan Liu YiNong Liu Bo Lu XueFeng Lu Tao Luo Xiang Ma Bin Meng Yi Nang JianYin Nie Ge OU JinLu Qu Na Sai Liang Sun Yin Tan Lian Tao WenHui Tao YouLi Tuo GuoFeng Wang HuanYu Wang Juan Wang WenShuai Wang YuSa Wang XiangYang Wen BoBing WU Mei Wu GuangCheng Xiao He Xu YuPeng Xu LinLi Yan JiaWei Yang Sheng Yang YanJi Yang AiMei Zhang ChunLei Zhang ChengMo Zhang Fan Zhang HongMei Zhang Juan Zhang Qiang Zhang Shu Zhang Tong Zhang Wei Zhang WanChang Zhang WenZhao Zhang Yi Zhang Yue Zhang YiFei Zhang YongJie Zhang Zhao Zhang ZiLiang Zhang HaiSheng Zhao JianLing Zhao XiaoFan Zhao ShiJie Zheng Yue Zhu YuXuan Zhu ChangLin Zou | 2018 | Science China(Physics,Mechanics & Astronomy)2018，61，3： | 12 |
| 3 | The enhanced X-ray Timing and Polarimetry mission—eXTP显示文摘In this paper we present the enhanced X-ray Timing and Polarimetry mission—eXTP. eXTP is a space science mission designed to study fundamental physics under extreme conditions of density, gravity and magnetism. The mission aims at determining the equation of state of matter at supra-nuclear density, measuring effects of QED, and understanding the dynamics of matter in strong-field gravity. In addition to investigating fundamental physics, eXTP will be a very powerful observatory for astrophysics that will provide observations of unprecedented quality on a variety of galactic and extragalactic objects. In particular, its wide field monitoring capabilities will be highly instrumental to detect the electro-magnetic counterparts of gravitational wave sources.The paper provides a detailed description of:(1) the technological and technical aspects, and the expected performance of the instruments of the scientific payload;(2) the elements and functions of the mission, from the spacecraft to the ground segment. | ShuangNan Zhang Andrea Santangelo Marco Feroci YuPeng Xu FangJun Lu Yong Chen Hua Feng Shu Zhang Sφren Brandt Margarita Hernanz Luca Baldini Enrico Bozzo Riccardo Campana Alessandra De Rosa YongWei Dong Yuri Evangelista Vladimir Karas Norbert Meidinger Aline Meuris Kirpal Nandra Teng Pan Giovanni Pareschi Piotr Orleanski QiuShi Huang Stephane Schanne Giorgia Sironi Daniele Spiga Jiri Svoboda Gianpiero Tagliaferri Christoph Tenzer Andrea Vacchi Silvia Zane Dave Walton ZhanShan Wang Berend Winter Xin Wu Jean J.M.in't Zand Mahdi Ahangarianabhari Giovanni Ambrosi Filippo Ambrosino Marco Barbera Stefano Basso Jörg Bayer Ronaldo Bellazzini Pierluigi Bellutti Bruna Bertucci Giuseppe Bertuccio Giacomo Borghi XueLei Cao Franck Cadoux Francesco Ceraudo TianXiang Chen Yu Peng Chen Jerome Chevenez Marta Civitani Wei Cui WeiWei Cui Thomas Dauser Ettore Del Monte Sergio Di Cosimo Sebastian Diebold Victor Doroshenko Michal Dovciak YuanYuan Du Lorenzo Ducci QingMei Fan Yannick Favre Fabio Fuschino JoséLuis Ga'lvez Min Gao MingYu Ge Olivier Gevin Marco Grassi QuanYing Gu YuDong Gu DaWei Han Bin Hong Wei Hu Long Ji ShuMei Jia WeiChun Jiang Thomas Kennedy Ingo Kreykenbohm Irfan Kuvvetli Claudio Labanti Luca Latronico Gang Li MaoShun Li Xian Li Wei Li ZhengWei Li Olivier Limousin HongWei Liu XiaoJing Liu Bo Lu Tao Luo Daniele Macera Piero Malcovati Adrian Martindale Malgorzata Michalska Bin Meng Massimo Minuti Alfredo Morbidini Fabio Muleri Stephane Paltani Emanuele Perinati Antonino Picciotto Claudio Piemonte JinLu Qu Alexandre Rachevski Irina Rashevskaya Jerome Rodriguez Thomas Schanz ZhengXiang Shen LiZhi Sheng JiangBo Song LiMing Song Carmelo Sgro Liang Sun Ying Tan Phil Uttley Bo Wang DianLong Wang GuoFeng Wang Juan Wang LangPing Wang YuSa Wang Anna L.Watts XiangYang Wen Jörn Wilms ShaoLin Xiong JiaWei Yang Sheng Yang YanJi Yang Nian Yu WenDa Zhang Gianluigi Zampa Nicola Zampa Andrzej A.Zdziarski AiMei Zhang ChengMo Zhang Fan Zhang Long Zhang Tong Zhang Yi Zhang XiaoLi Zhang ZiLiang Zhang BaoSheng Zhao ShiJie Zheng Yu Peng Zhou Nicola Zorzi J.Frans Zwart | 2019 | Science China(Physics,Mechanics & Astronomy)2019，62，2： | 11 |
| 4 | Bacterial Community and Function of Biological Activated Carbon Filter in Drinking Water Treatment显示文摘Objective It aims to investigate the changes in composition and structure of bacterial communities de-veloping on biological activated carbon (BAC) particles, and the bacterial functions. Method A pilot plant had been in service for 180 days, aiming to develop bacterial communities on acti-vated carbon naturally. After 180 days of operation, the bacterial communities were determined by dena-turing gradient gel electrophoresis (DGGE) analyses of PCR-amplified 16S rRNA genes. The study on community composition and the phylogenetic relationships of the organisms was complemented by a se-quence analysis of cloned PCR products from 16S rRNA genes. Gas chromatorgaphy-mass (GC-MS) mea-surement was used to determine organic chemical composition of inflow and outflow water on the 300th day. TOC and NH 4 + -N were also tested in this experiment. Results It showed that the stable bacterial structure did not develop on BAC particles until the 9th month during running time of the BAC filter. The communities were finally dominated by Pseudomonas sp., Ba-cillus sp., Nitrospira sp., and an uncultured bacterium. Stable bacterial communities played an important role in removal of NH 4 + -N and total organic carbon (TOC). Results from gas chromatorgaphy-mass (GC-MS) showed that 36 kinds of chemicals in feed water were eliminated, and concentrations of 5 kinds of chemicals decreased. These chemicals served as nutrients for the dominant bacteria. Conclusion The findings from the study suggested that the stability of microbial structure was beneficial for improving NH 4 + -N and TOC removal efficiencies. The dominant bacteria had the advantage of biode-grading a wide range of organic chemicals and NH 4 + -N. | ZHANG DuoYing LI WeiGuang ZHANG ShuMei LIU Miao ZHAO XiaoYu ZHANG XianCheng | 2011 | Biomedical and Environmental Sciences2011，24，2： | 8 |
| 5 | Nine-month angiographic and two-year clinical follow-up of polymer-free sirolimus-eluting stent versus durable-polymer sirolimus-eluting stent for coronary artery disease: the Nano randomized trial显示文摘 | Zhang Yaojun Chen Fang Takashi Muramatsu Xu Bo Li Zhanquan Ge Junbo He Qing Yang Zhijian Li Shumei Wang Lefeng Wang Haichang He Ben Li Kang Qi Guoxian Li Tianchang Zeng Hesong Peng Jianjun Jiang Tieming Zeng Qiutang Zhu Jianhua Fu Guosheng Christos V. Bourantas Patrick W. Serruys Huo Yong | 2014 | Chinese Medical Journal2014，，11： | 8 |
| 6 | Basin assemblages and tectonic evolution in the Bohai Gulfand its neighbors显示文摘According to multi- disciplinary research advances in recent years, three blocks which named Jiaoliao - Bohai block, central North China block and Ordos block are divided. The differences of the tectonic association, types, styles and features in the space, and evolution from Archaean to Cenozoic in the time, between the former two blocks are discussed. Tectonic features and evolution in the four tectonic stages of Precambrian, Indo- China, Yanshanian and Cenozoic are emphasized especially here. All of them described above have inherit and neogenic property. The temporal-spatial change and interaction among basin assemblages in the above four stages are analyzed. Escape tectonic model is employed to interpret coeval compressive and extensional basins in the study area. | Li Sanzhong Xu Shumei Shan Yehua Li Xishuang Zhou Lihong Hao Yinquan Fan Zheqing Liang Huilan | 2000 | Acta Oceanologica Sinica2000，19，4： | 7 |
| 7 | An infectious disease of ducks caused by a newly emerged Tembusu virus strain in mainland China显示文摘 | Pixi Yan Youshu Zhao Xu Zhang Dawei Xu Xiaoguang Dai Qiaoyang Teng Liping Yan Jiewen Zhou Xiwen Ji Shumei Zhang Guangqing Liu Yanjun Zhou Yoshihiro Kawaoka Guangzhi Tong Zejun Li | 2011 | Virology2011，，1： | 5 |
| 8 | A study of soil organic carbon distribution and storage in the Northeast Plain of China显示文摘采用联合起来的土壤碳数量(USCA ) 途径,土壤碳存储基于在 20042006 进行的多种用途的地区性的 Geochemical 调查(MRGS ) 越过中国的东北平原被计算。结果显示在表层土(00.2 m ) 的器官的碳(SOC ) 存储,心土(01 m ) 和深土壤(01.8 m ) 是的土壤有 3327.8 t/km2, 12,904.7 t/km2 和 16,157.5 t/km2 的密度的 768.1 山, 2978.4 山和 3729.2 山分别地。而土壤碳密度从东北平原(辽宁)的南部的区域显示出一个清楚的增加趋势,这些价值以表层土特别地与国家一般水准一致,到中间(吉林)和北平原( Heilongjiang )碳密度,从 2284.2 增加了,到 3436.7 和 3861.5 t/km2 ,分别地。与在 19841986 从第二国家土壤调查获得的碳数据(SNSS ) 相比,从 MRGS 的表层土 SOC 存储值被发现由 320.59 山(29.4%) 减少了,与在 20 年的 16.0 山(l.73%) 的平均年度衰落。在平原的南部、中间、北的区域,分别地,土壤碳密度为整个平原与 1389.0 t/km2 的平均价值由 1060.6 t/km2, 1646.4 t/km2 和 1300.2 t/km2 减少了。这些调查结果显示在土壤碳密度的减少根据不同生态系统和陆地使用类型变化了。因此,土壤碳密度的比率被计算以便学习碳,并且进一步探索分发特征在生态系统之间的动态平衡,以及 SOC 的隐遁潜力。 | Xiaohuan Xi Zhongfang Yang Yujun Cui Shumei Sun Chengguang Yu Min Li | 2011 | Geoscience Frontiers2011，2，2： | 5 |
| 9 | Quantitative response of oil sunflower yield to evapotranspiration and soil salinity with saline water irrigation显示文摘Appropriate application of water-salt-crop function model can optimize agricultural water management in regions with declining water supply,such as the Hetao district.Appropriate use of saline water is also based on the effects of irrigation water demand and water quality on crop growth quantitatively.Therefore,oil sunflower growth testing under both water and salt stress was completed from 2013 to 2014.Water salinity levels at 1.7 ds/m,4 ds/m,6 ds/m and 8 ds/m were used in the experiments.Two water deficit levels were reported,60%and 80%of the irrigation quota,which were considered moderate and mild deficit levels,respectively.All treatments were applied in planting the oil sunflower in critical growing periods,namely,floral initiation,anthesis and maturity.Linear,Cobb-Douglas,quadratic and transcendental function models were used to simulate the relative yield,evapotranspiration(ET)and electrical conductivity(EC).The predictive ability and sensitivity of each model were then evaluated.Compared with salt stress,water stress exerted a more significant effect on the oil sunflower yield;the water parameters(a1 and a3)were most sensitive in the water-salt-crop function model.Oil sunflower was most sensitive to water and salt stress during anthesis.The transcendental function generally showed a relatively high sensitivity coefficient and a relatively small statistical error.Therefore,the transcendental function is the most appropriate model for simulating and predicting the yield of oil sunflower irrigated with saline water.Applying the water-salt-crop function model in planting of oil sunflower can help in the development and utilization of saline water in the Hetao district. | He Xin Yang Peiling Ren Shumei Li Yunkai Jiang Guangyu Li Lianhao | 2016 | International Journal of Agricultural and Biological Engineering2016，9，2： | 4 |
| 10 | A review of whole-process control of industrial volatile organic compounds in China显示文摘Volatile organic compounds(VOCs)play an important role in the formation of ground-level ozone and secondary organic aerosol(SOA),and they have been key issues in current air pollution prevention and control in China.Considerable attention has been paid to industrial activities due to their large and relatively complex VOCs emissions.The present research aims to provide a comprehensive review on whole-process control of industrial VOCs,which mainly includes source reduction,collection enhancement and end-pipe treatments.Lower VOCs materials including water-borne ones are the keys to source substitution in industries related to coating and solvent usage,leak detection and repair(LDAR)should be regarded as an efficient means of source reduction in refining,petrochemical and other chemical industries.Several types of VOCs collection methods such as gas-collecting hoods,airtight partitions and others are discussed,and airtight collection at negative pressure yields the best collection efficiency.Current end-pipe treatments like UV oxidation,low-temperature plasma,activated carbon adsorption,combustion,biodegradation,and adsorption-combustion are discussed in detail.Finally,several recommendations are made for future advanced treatment and policy development in industrial VOCs emission control. | Hailin Wang Shumei Sun Lei Nie Zhongshen Zhang Wenpeng Li Zhengping Hao | 2023 | Journal of Environmental Sciences2023，，1： | 4 |
| 11 | Mechanism Analysis of Stiffness Improvement by Waterborne Epoxy Resin Surface Sizing Agent显示文摘Low-basis-weight paper lacks normal strength and stiffness. Waterborne epoxy resin could be employed with oxidized starch to improve paper stiffness through surface sizing. In this study,the mechanism of enhancing stiffness by adding waterborne epoxy resin was fully investigated. The results indicated that through surface sizing with epoxy resin,the paper thickness was preserved,whereas the elastic modulus increased significantly and the epoxy resin had positive impact on single fiber strength. A rigid resin layer and interpenetrating polymer network formed on the surface and in the inner layer of the paper,respectively. The formed resin layer and interpenetrating polymer network strongly supported the paper,leading to the improvement of the elastic modulus and stiffness. The stiffness improvement through surface sizing was mainly due to the formation of a fibrous composite layer and penetration of the sizing agent into the inner layers of the paper. The better the combination between fiber and sizing agent,the higher were the elastic modulus and the stiffness of the whole paper. | Hui Xu ShuMei Wang YuanYuan Li HongQi Dai | 2016 | Paper And Biomaterials2016，1，1： | 4 |
| 12 | Synthesis, DNA-binding and photocleavage studies of ruthenium(Ⅱ) complexes [Ru(btz)_3]^(2+) and [Ru(btz)(dppz)_2]^(2+)显示文摘Two new ruthenium(Ⅱ) complexes, [Ru(btz)3](ClO4)2 (1) and [Ru(btz)(dppz)2](ClO4)2 (2) (btz = 4,4′-bithi-azole, dppz = dipyrido[3,2-a:2′,3′-c]phenazine), have been synthesized and characterized by elemental analysis, 1H NMR, ES-MS and X-ray crystallography. The DNA binding behaviors of two complexes have been studied by spectroscopic and viscosity measurements. The results suggest that complex 1 binds to CT-DNA via an electrostatic mode, while complex 2 via an intercalative mode. Under irradiation at 365 nm, both complexes were found to promote the cleavage of plasmid pBR 322 DNA from supercoiled form Ⅰ to nicked form Ⅱ. The mechanism studies reveal that singlet oxygen 1O2 and hydroxyl radical (OH-) play a significant role in the photocleavage process. | YU HuiJuan, HUANG ShuMei, KOU JunFeng, LI LvYing, JIA HaiNa, CHAO Hui & JI LiangNian MOE Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry and Chemical Engineering, Sun Yat-Sen University, Guangzhou 510275, China | 2009 | Science China Chemistry2009，52，9： | 4 |
| 13 | Effect of cooling pad installation on indoor airflow distribution in a tunnel-ventilated laying-hen house显示文摘Extra cooling pads on the sidewalls are needed for larger poultry houses using tunnel ventilation system.Preliminary study showed that the airflow velocity going through different aisles varies greatly when the extra pads are installed at the end of sidewalls,making a“[”-shape air inlet.Combined with field tests,the CFD(computational fluid dynamics)technology was used to study the uniformity of airflow distribution in a tunnel-ventilated laying-hen house.The air distribution was first monitored in a layer house to find the main reason resulting in the variations of airflows in different aisles.Then CFD simulations were carried out with different distances(D=2 m,3 m or 4 m)between the pads on end-wall and the extra pads on side walls.The field test showed that airflow streams from the different groups of cooling pads collided vertically at the house corners,mixed with each other,then flew towards the center of the house.This was the main reason that the wind speed in the middle aisle was much higher than in other aisles,leaving large zones of lower ventilation in the aisles adjacent to the sidewalls.The results of CFD simulations indicated that air distributions could be significantly improved when the extra pieces of pads were moved away for an appropriate distance from the end coolingpads.As far as conventional poultry house with a span of 12 m,the air speeds in different aisles were more uniform when this distance was about 3 m. | Hui Xue Zhu Qiang Ji-Qin Ni Li Baoming Shi Zhengxiang Zhao Shumei Wang Yu | 2016 | International Journal of Agricultural and Biological Engineering2016，9，4： | 4 |
| 14 | Gigantic electric-field-induced second harmonic generation from an organic conjugated polymer enhanced by a band-edge effect显示文摘Electric-field-induced second harmonic generation(EFISH),a third-order nonlinear process,arises from the interaction between the electric field of an external bias and that of two incident photons.EFISH can be used to dynamically control the nonlinear optical response of materials and is therefore promising for active nonlinear devices.However,it has been challenging to achieve a strong modulation with EFISH in conventional nonlinear materials.Here,we report a large tunability of an EFISH signal from a subwavelength-thick polymer film sandwiched between a transparent electrode and a metallic mirror.By exploiting the band-edge-enhanced third-order nonlinear susceptibility of the organic conjugated polymer,we successfully demonstrate a gigantic EFISH effect with a modulation ratio up to 422%V^(−1) at a pumping wavelength of 840 nm.The band-edge-enhanced EFISH opens new avenues for modulating the intensity of SHG signals and for controlling nonlinear electro-optic interactions in nanophotonic devices. | Shumei Chen King Fai Li Guixin Li Kok Wai Cheah Shuang Zhang | 2019 | Light(Science & Applications)2019，8，1： | 3 |
| 15 | Overview to the Hard X-ray Modulation Telescope (Insight-HXMT) Satellite显示文摘As China’s first X-ray astronomical satellite, the Hard X-ray Modulation Telescope (HXMT), which was dubbed as Insight-HXMT after the launch on June 15, 2017, is a wide-band(1-250 ke V) slat-collimator-based X-ray astronomy satellite with the capability of all-sky monitoring in 0.2-3 Me V. It was designed to perform pointing, scanning and gamma-ray burst(GRB)observations and, based on the Direct Demodulation Method (DDM), the image of the scanned sky region can be reconstructed.Here we give an overview of the mission and its progresses, including payload, core sciences, ground calibration/facility, ground segment, data archive, software, in-orbit performance, calibration, background model, observations and some preliminary results. | Shuang-Nan Zhang TiPei Li FangJun Lu LiMing Song YuPeng X u CongZhan Liu Yong Chen XueLei Cao QingCui Bu Zhi Chang Gang Chen Li Chen TianXiang Chen YiBao Chen YuPeng Chen Wei Cui WeiWei Cui JingKang Deng YongWei Dong Yuan Yuan Du MinXue Fu GuanHua Gao He Gao Min Gao MingYu Ge YuDong Gu Ju Guan Can Gungor ChengCheng Guo DaWei Han Wei Hu Yue Huang Jia Huo ShuMei Jia LuHua Jiang WeiChun Jiang Jing Jin YongJie Jin Bing Li ChengKui Li Gang Li MaoShun Li Wei Li Xian Li XiaoBo Li XuFang Li YanGuo Li ZiJian Li ZhengWei Li XiaoHua Liang JinYuan Liao GuoQing Liu HongWei Liu ShaoZhen Liu XiaoJing Liu Yuan Liu YiNong Liu Bo Lu XueFeng Lu Tao Luo Xiang Ma Bin Meng Yi Nang JianYin Nie Ge Ou JinLu Qu Na Sai RenCheng Shang GuoHong Shen Liang Sun Ying Tan Lian Tao YouLi Tuo Chen Wang ChunQin Wang GuoFeng Wang HuanYu Wang Juan Wang WenShuai Wang YuSa Wang XiangYang Wen BaiYang Wu BoBing Wu Mei Wu GuangCheng Xiao ShaoLin Xiong LinLi Yan JiaWei Yang Sheng Yang YanJi Yang QiBin Yi Bin Yuan AiMei Zhang ChunLei Zhang ChengMo Zhang Fan Zhang HongMei Zhang Juan Zhang Qiang Zhang ShenYi Zhangs Shu Zhang Tong Zhang WanChang Zhang Wei Zhang WenZhao Zhang Yi Zhang YiFei Zhang YongJie Zhang Yue Zhang Zhao Zhang Zhi Zhang ZiLiang Zhang HaiSheng Zhao XiaoFan Zhao ShiJie Zheng JianFeng Zhou YuXuan Zhu Yue Zhu RenLin Zhuang | 2020 | Science China(Physics,Mechanics & Astronomy)2020，63，4： | 2 |
| 16 | Enhanced mechanical and thermal properties of γ-allyloxymethyl 18-crown-6 and polyimide composites through hydrosilylation crosslinking显示文摘The complexation of y-allyloxymethyl 18-crown-6(AC6) induced inferior mechanical and thermal properties of polyimide(PI) in spite of lowered dielectric constant(k). To solve this puzzle, tetrakis-(di methylsiloxy)-si lane was employed to crosslink the complex of AC6 and PI(AC6-PI) through hydrosilylation reaction. The crosslinked AC6-PI(SiAC-PI) composites possessed excellent mechanical and thermal properties as well as low k. The tensile strength and fracture energy of SiAC-PI were increased by 87% and 716%, and the glass transition temperature and 5% weight loss temperature elevated 14.5 ℃ and 38.8 ℃, respectively, compared with those of AC6-PI. The structure of SiAC-PI was characterized by FTIR spectra, crosslinked density and XRD diffraction patterns. | Chuqi Shi Shumei Liu Yang Li Jianqing Zhao Haohao Huang | 2019 | Chinese Chemical Letters2019，30，3： | 2 |
| 17 | Ultrastructural characterization of avian influenza A(H7N9) virus infecting humans in China显示文摘Dear Editor,In March 2013,the first 3 cases of severe disease dueto a novel avian-origin influenza A(H7N9)virus weredetected in the Chinese provinces of Shanghai and Anhui(Gao R,et al.,2013).A total of 339 laboratory-confirmedcases with 100 deaths were reported until January 142014(WHO,2014).To the best of our knowledge,thisis the first time that human infection with the avian in-fluenza A H7N9 subtype has been detected.Prior to | Rongbao Gao Jingdong Song Ye Zhang Shumei Zou Tian Bai Xiaodan Li Jianguo Qu Jianfang Zhou Tao Hung Yuelong Shu | 2014 | Virologica Sinica2014，29，2： | 2 |
| 18 | CFD and digital particle tracking to assess flow characteristics in the labyrinth flow path of a drip irrigation emitter显示文摘 | Yunkai Li Peiling Yang Tingwu Xu Shumei Ren Xiongcai Lin Runjie Wei Hongbing Xu | 2008 | Irrigation Science2008，，5： | 2 |
| 19 | Promising flu- orescent probes from phycobiliproteins 显示文摘 | Sun Li Wang Shumei Chen Lixue | 2003 | Selected Topics in Quantum Electronics2003，9，2： | 1 |
| 20 | The S190R mutation in the hemagglutinin protein of pandemic H1N1 2009 influenza virus increased its pathogenicity in mice显示文摘Human influenza viruses preferentially bind to sialic acid-α2,6-galactose (SAα2,6Gal) receptors, which are predominant in human upper respiratory epithelia, whereas avian influenza viruses preferentially bind to SAα2,3Gal receptors. However, variants with amino acid substitutions around the receptor-binding sites of the hemagglutinin (HA) protein can be selected after several passages of human influenza viruses from patients’ respiratory samples in the allantoic cavities of embryonated chicken eggs. In this study, we detected an egg-adapted HA S190R mutation in the pandemic H1N1 virus 2009 (pdmH1N1), and evaluated the effects of this mutation on receptor binding affinity and pathogenicity in mice. Our results revealed that residue 190 is located within the pocket structure of the receptor binding site. The single mutation to arginine at position 190 slightly increased the binding affinity of the virus to the avian receptor and decreased its binding to the long human α2,6-linked sialic acid receptor. Our study demonstrated that the S190R mutation resulted in earlier death and higher weight loss in mice compared with the wild-type virus. Higher viral titers at 1 dpi (days post infection) and diffuse damage at 4 dpi were observed in the lung tissues of mice infected with the mutant virus. | Yongkun Chen Tian Bai Wenfei Zhu Rongbao Gao Zhihong Deng Yi Shi Shumei Zou Yiwei Huang Xiyan Li Fangcai Li Zhaomin Feng Tao Chen Jing Yang Dayan Wang Lidong Gao Yuelong Shu | 2018 | Science China(Life Sciences)2018，61，7： | 1 |
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