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| 1 | Screening and Surveillance for the Early Detection of Colorectal Cancer and Adenomatous Polyps, 2008: A Joint Guideline From the American Cancer Society, the US Multi-Society Task Force on Colorectal Cancer, and the American College of Radiology显示文摘 | Bernard Levin David A. Lieberman Beth McFarland Kimberly S. Andrews Durado Brooks John Bond Chiranjeev Dash Francis M. Giardiello Seth Glick David Johnson C. Daniel Johnson Theodore R. Levin Perry J. Pickhardt Douglas K. Rex Robert A. Smith Alan Thorson S | 2008 | Gastroenterology2008，，5： | 8 |
| 2 | Adaptive and maladaptive expression of the mRNA regulatory protein HuR显示文摘The RNA-binding proteins involved in regulation of mRNA post-transcriptional processing and translation control the fates of thousands of mRNA transcripts and basic cellular processes. The best studied of these, HuR, is well characterized as a mediator of mRNA stability and translation, and more recently, as a factor in nuclear functions such as pre-mRNA splicing. Due to HuR's role in regulating thousands of mRNA transcripts, including those for other RNA-binding proteins, HuR can act as a master regulator of cell survival and proliferation. HuR itself is subject to multiple post-translationa modifications including regulation of its nucleocytoplasmic distribution. However, the mechanisms that govern HuR levels in the cell have only recently begun to be defined. These mechanisms are critical to cell health, as it has become clear in recent years that aberrant expression of HuR can lead alternately to decreased cell viability or to promotion of pathological proliferation and invasiveness. HuR is expressed as alternate mRNAs that vary in their untranslated regions, leading to differences in transcript stability and translatability. Multiple transcription factors and modulators of mRNA stability that regulate HuR mRNA expression have been identified. In addition, translation of HuR is regulated by numerous microRNAs, several of which have been demonstrated to have anti-tumor properties due to their suppression of HuR expression. This review summarizes the current state of knowledge of the factors that regulate HuR expression, along with the circumstances under which these factors contribute to cancer and inflammation. | Suman Govindaraju Beth S Lee | 2013 | World Journal of Biological Chemistry2013，4，4： | 7 |
| 3 | Green tea extract:A potential cause of acute liver failure显示文摘The use of herbal products has increased significantly in recent years.Because these products are not subject to regulation by the Food and Drug Administration and are often used without supervision by a healthcare provider,the indication for and consumption of these supplements is quite variable.Moreover,their use is generally regarded as safe and natural by the lay-public.Unfortunately,there has been an increase in the number of reported adverse events occurring with the use of herbal products.We present a case of acute impending liver failure in an adolescent male using a weightloss product containing green tea extract.Our case adds to the growing concern surrounding the ingestion of green tea extract and serves to heighten healthcare provider awareness of a potential green tea extract hepatotoxicity.Despite the generally touted benefits of green tea as a whole,clinical concern regarding its use is emerging and has been linked to its concentration in multiple herbal supplements.Interestingly,the suspected harmful compounds are those previously proposed to be advantageous for weight-loss,cancer remedy,and anti-inflammatory purposes.Yet,we emphasize the need to be aware of not just green tea extract,but the importance of monitoring patient use of all dietary supplements and herbal products. | Shreena S Patel Stacey Beer Debra L Kearney Garrett Phillips Beth A Carter | 2013 | World Journal of Gastroenterology2013，19，31： | 3 |
| 4 | ATP: an extracellular signaling molecule between neurons and glia显示文摘 | Douglas FR Beth S | 2000 | Trends Neurosci2000，23，： | 1 |
| 5 | Serelaxin, recombinant human relaxin-2, for treatment of acute heart failure (RELAX-AHF): a randomised, placebo-controlled trial显示文摘 | John R Teerlink Gad Cotter Beth A Davison G Michael Felker Gerasimos Filippatos Barry H Greenberg Piotr Ponikowski Elaine Unemori Adriaan A Voors Kirkwood F Adams Maria I Dorobantu Liliana R Grinfeld Guillaume Jondeau Alon Marmor Josep Masip Peter S Pang | 2013 | The Lancet . 2013 (9860)2013，，9860： | 1 |
| 6 | A suivey of data provenance in e-science显示文摘 | Yogesh L S Beth P Dennis G | 2005 | SIGMOD Record2005，34，3： | 1 |
| 7 | The prognostic significance of thrombocytosis in epithelial ovarian carcinoma显示文摘 | Andrew J Li Alison C Madden Ilana Cass Ronald S Leuchter Leo D Lagasse Beth Y Karlan | 2003 | Gynecologic Oncology2003，，1： | 1 |
| 8 | Computational and experimental study of axisymmetric coflow partially premixed methane/air flames显示文摘 | Beth A V B Charles S M Lisa D P | 2000 | Combustion and Flame2000，123，4： | 1 |
| 9 | Guidelines for the use of an insulin infusion for the management of hyperglycemia in critically ill patients显示文摘 | Judith Jacobi Nicholas Bircher James Krinsley Michael Agus Susan S. Braithwaite Clifford Deutschman Amado X. Freire Douglas Geehan Benjamin Kohl Stanley A. Nasraway Mark Rigby Karen Sands Lynn Schallom Beth Taylor Guillermo Umpierrez John Mazuski Holger S | 2012 | Critical Care Medicine2012，，12： | 1 |
| 10 | Improvement of the composting time for household waste during an initial low pH phase by mesophilic temperature control显示文摘 | Srnars S Gustafsson L Beth - Friis B | 2002 | Bioresource Technology2002，84，： | 1 |
| 11 | Organizational citizenship behaviors:a critical review of the theoretical and empirical literature and suggest ions for future research显示文摘 | Podsakoff P M Mac Kenzie S B Julie Beth Paine | 2000 | Journal of Management2000，，3： | 1 |
| 12 | Role of preoperative ultrasonography in the surgical management of patients with thyroid cancer显示文摘 | Maria A Kouvaraki Suzanne E Shapiro Bruno D Fornage Beth S Edeiken-Monro Steven I Sherman Rena Vassilopoulou-Sellin Jeffrey E Lee Douglas B Evans | 2003 | Surgery2003，，6： | 1 |
| 13 | Patient and Facility Safety in Hemodialysis: Opportunities and Strategies to Develop a Culture of Safety显示文摘 | Renee G Alan K Beth S | 2012 | Clin J Am Soc Nephrol2012，7，4： | 1 |
| 14 | Metrics for ranking the performance of supercomputers显示文摘 | Tzu Y C Meghan G Beth S | 2006 | CTWatch2006，2，4： | 1 |
| 15 | Segmental tuberous sclerosis presenting as unilateral facial angiofibromas显示文摘 | Michael A Trauner Beth S Ruben Peter J Lynch | 2003 | Journal of the American Academy of Dermatology2003，，2： | 1 |
| 16 | Estimation of saliva production in crib-biting and normal horses显示文摘 | Beth A M Cynthia A McC Sara J S | 2008 | J Equine Vet Sci2008，28，2： | 1 |
| 17 | In - Home Services for the Dependent Elderly : Determinants of Current Use and Implications for Future Demand显示文摘 | BETH J S | 1985 | Research on Aging1985，，1： | 1 |
| 18 | Species relationship based on sequences of the mitochondrial Cytb gene显示文摘 | Frank BG Beth S Frededck HS | | 0，，01： | 1 |
| 19 | Reverse genetic characterization of cytosolic aeetyl - CoA generation by ATP- Citrate Lyase in Arabidopsis显示文摘 | Beth L F Basil J N Wurtelea E S | 2005 | The Plant Cell2005，17，： | 1 |
| 20 | Synthetic latex products显示文摘 | Beth W Mcnin W Scott S et a1 | 1995 | Adhesives Age1995，，11： | 1 |
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