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    题名 作者 年代 出处 被引量
1Clean Coal Technologies in China: Current Status and Future Perspectives显示文摘Shiyan Chang Jiankun Zhuo Shuo Meng Shiyue Qin Qiang Yao 2016Engineering2016,2,4:43
2Cardiomyocyte overexpression of miR-27b induces cardiac hypertrophy and dysfunction in mice显示文摘最近的研究开始在心脏的肥大和机能障碍的致病揭示了 microRNAs (miRNAs ) 的关键角色。在这研究,我们测试了是否转变生长 factor-β(TGF-β) 调整 miRNA 在心脏的肥大和心失败(HF ) 的发展起了一个枢轴的作用。我们观察到 miR-27b 是在 cardiomyocyte 特定的 Smad4 猛烈老鼠的心的 upregulated,它开发了心脏的肥大。在 vitro,实验证明 miR-27b 表示能被 TGF-β 禁止; 1 并且它的 overexpression 支持了 hypertrophic 房间生长,当 miR-27b 抑制导致了 hypertrophic 房间的抑制时,生长由 phenylephrine (PE ) 引起了处理。而且,有 miR-27b 的 cardiomyocyte 特定的 overexpression 的转基因的老鼠的分析表明 miR-27b overexpression 是足够的导致心脏的肥大和机能障碍。我们验证了 peroxisome 激活 proliferator 的 receptor-γ(PPAR-γ) 作为在 cardiomyocyte 的 miR-27b 的一个直接目标。一致地, miR-27b 转基因的老鼠显著地显示了 PPAR-γ 的底层;比控制鼠标。而且,在用在一只 pressure-overload-induced 老鼠的特定的 antagomir 的 miR-27b 的 vivo silencing, HF 的模型增加了心脏的 PPAR-γ表示,稀释心脏的肥大和机能障碍。我们的学习的结果表明那 TGF-β 1-regulated miR-27b 涉及心脏的肥大的规定,并且为心脏病作为一个有效治疗学的目标验证 miR-27b。Jian Wang Yao Song Yan Zhang Han Xiao Qiang Sun Ning Hou Shuilong Guo Youliang Wang Kaiji Fan Dawei Zhan Lagabaiyila Zha Yang Cao Zhenhua Li Xuan Cheng Youyi Zhang Xiao Yang 2012Cell Research2012,22,3:36
3Broadband diffusion of terahertz waves by multi-bit coding metasurfaces显示文摘The terahertz region is a special region of the electromagnetic spectrum that incorporates the advantages of both microwaves and infrared light waves.In the past decade,metamaterials with effective medium parameters or gradient phases have been studied to control terahertz waves and realize functional devices.Here,we present a new approach to manipulate terahertz waves by using coding metasurfaces that are composed of digital coding elements.We propose a general coding unit based on a Minkowski closed-loop particle that is capable of generating 1-bit coding(with two phase states of 0 and 180°),2-bit coding(with four phase states of 0,90°,180°,and 270°),and multi-bit coding elements in the terahertz frequencies by using different geometric scales.We show that multi-bit coding metasurfaces have strong abilities to control terahertz waves by designing-specific coding sequences.As an application,we demonstrate a new scattering strategy of terahertz waves—broadband and wide-angle diffusion—using a 2-bit coding metasurface with a special coding design and verify it by both numerical simulations and experiments.The presented method opens a new route to reducing the scattering of terahertz waves.Li-Hua Gao Qiang Cheng Jing Yang Shao-Jie Ma Jie Zhao Shuo Liu Hai-Bing Chen Qiong He Wei-Xiang Jiang Hui-Feng Ma Qi-Ye Wen Lan-Ju Liang Biao-Bing Jin Wei-Wei Liu Lei Zhou Jian-Quan Yao Pei-Heng Wu Tie-Jun Cui 2015Light(Science & Applications)2015,4,1:31
4Specific CEA-producing colorectal carcinoma cell killing with recombinant adenoviral vector containing cytosine deaminase gene显示文摘瞄准:到杀死 CEA 积极颜色明确地使用 E 关口 i cytosine 脱氨基酶(CD ) 的表面的癌房间自杀基因,新复制缺乏的 recombinant adenoviral 向量在在哪个 CD,基因在 CEA 倡导者下面被控制被构造并且它的在里面 vitro 细胞毒素的效果被评估。方法:梭原生质标志包含 CD 基因和 CEA 基因的规章的顺序在 293 房间紧张与侵入人体气管粘膜的病菌染色体 DNA 的右手臂被构造并且重新结合。点弄污, PCR 被用来识别积极的匾。侵入人体气管粘膜的病菌的纯化被执行与在 CsCl 步坡度和滴定极端集中与匾形成试金被测量。细胞毒素的效果是有 MTT 方法的 assayed, 5-FC 的百分之五十抑制集中(IC (50 )) 用一个曲线试穿参数被计算。表面的癌房间线,是生产 CEA,和 CEA-nonproducing Hela 房间衬里的人的颜色在 cytological 测试被使用。确定的 recombinant 侵入人体气管粘膜的病菌向量 AdCMVCD, CD 基因在 CMV 倡导者下面在被控制,被用作病毒控制。量的结果被表示为平均数的吝啬的 +/- SD。统计分析用 ANOVA 测试被执行。结果:需要的 recombinant 侵入人体气管粘膜的病菌向量被称为 AdCEACD。点弄污和 PCR 的结果证明 recombinant 侵入人体气管粘膜的病菌包含了 CEA 倡导者和 CD 基因。病毒 titer 是大约 5.0 X 10 (14 ) pfu/L (在纯化以后的 -1) 。 生产CEA Lovo 房间对 5-FC 敏感并且与 AdCEACD 和 AdCMVCD 在感染以后有一样的细胞毒素的效果(在父母 Lovo 房间,感染 100 M.O.I AdCEACD 的 Lovo 房间和感染 10 M.O.I AdCMVCD 的 Lovo 房间的 5-FC 的 IC ( 50 )价值是 >15000 , 216.5+/-38.1 和 128.8+/-25.4 micromol.L (-1), P<0.001 ,分别地),并且当侵入人体气管粘膜的病菌的 m.o.i 被提高时, 5-FC 的 cytotoxicity 因此增加了( 5-FC 的 IC ( 50 )的价值被归结为 27.9+/-4.2 micromol.L (在 1000 M.O.I AdCEACD 的-1)感染了 Lovo 房间和 24.8+/-7.1 micromol.L (在 100 M.O.I AdCMVCD 的-1)感染了 Lovo 房间, P<0.05 , P<0.01 ,分别地)。CEA-nonproducing Hela 房间没与 AdCEACD 在感染以后有效果,但是 Hela 房间与 AdCMVCD 在感染以后有细胞毒素的敏感到 5-FC (在在 10 M.O.I 感染 AdCMVCD 的父母 Hele 房间和 Hela 房间的 5-FC 的 IC (50 ) 是 >15000 和 214.5+/-31.3 micromol.L (-1), P<0.001 ) 。AdCEACD/5-FC 系统也有旁观者效果,并且当 transfected 房间的比例仅仅是 10% 时,生存能力是大约 30% 。结论:recombinant 侵入人体气管粘膜的病菌向量 AdCEACD 有房间的特性类型特定的基因交货。AdCEACD/5-FC 系统可以变得一新,为 CEA 积极的瘤的基因治疗的有势力和特定的途径,特别结肠癌。Li-Zong Shen Wen-Xi Wu Qiang Ding Yi-Bing Hua,Department of General Surgery,The First Affiliated Hospital of Nanjing Medical University,Nanjing,210029,Jiangsu Province,China De-Hua Xu Zhong-Cheng Zheng Xin-Yuan Liu,Shanghai Institute of Biochemistry and Cell Biology,The Chinese Academy of Sciences,Shanghai,200031,China Kun Yao,Department of Microbiology and Immunology,Nanjing Medical University,Nanjing,210029,Jiangsu Province,China 2002World Journal of Gastroenterology2002,8,2:29
5Homology-mediated end joining-based targeted integration using CRISPR/Cas9显示文摘Yao, Xuan Wang, Xing Hu, Xinde Liu, Zhen Liu, Junlai Zhou, Haibo Shen, Xiaowen Wei, Yu Huang, Zijian Ying, Wenqin Wang, Yan Nie, Yan-Hong Zhang, Chen-Chen Li, Sanlan Cheng, Leping Wang, Qifang Wu, Yan Huang, Pengyu Sun, Qiang Shi, Linyu Yang, Hui 2017Cell Research2017,27,6:28
6A comprehensive review of Energy Internet: basic concept,operation and planning methods, and research prospects显示文摘With the intensifying energy crisis and environmental pollution, the Energy Internet and corresponding patterns of energy use have been attracting more and more attention. In this paper, the basic concept and characteristics of the Energy Internet are summarized, and its basic structural framework is analyzed in detail. On this basis,couplings between the electric power system and other systems such as the cooling and heating system, the natural gas system, and the traffic system are analyzed, and the operation and planning of integrated energy systems in both deterministic and uncertain environments are comprehensively reviewed. Finally, the research prospects and main technical challenges of the Energy Internet are discussed.Yijia CAO Qiang LI Yi TAN Yong LI Yuanyang CHEN Xia SHAO Yao ZOU 2018Journal of Modern Power Systems and Clean Energy2018,6,3:25
7Changes of activated circulating endothelial cells and survivin in patients with non-small cell lung cancer after antiangiogenesis therapy显示文摘背景尽管 antiangiogenesis 治疗与它的公认的功效和细微不利效果在反肿瘤的治疗起一个重要作用,没有未来的临床的试用为预言 antiangiogenic therapy.This 学习的功效被承担在预言非小的 cel 的 therapy.Methods 病人的功效在 anti-angiogenesis 治疗和他们的意义以后调查激活的传播 endothelial 房间( aCECs )和 survMnWANG Jing HUANG Chun WEI Xi-yin QI Da-liang GONG Li-qun MU Hai-yu YAO Qiang LI Kai 2008Chinese Medical Journal2008,,22:24
8New composite grouting materials:Modified urea-formaldehyde resin with cement显示文摘A new composite two component grout comprised of modified urea-formaldehyde resin and cement was formulated to take account of the advantages and disadvantages of both the cement grout and the chemical grout.The new grout is designed for water blocking by reinforcing as well as seepage control by bore grouting.The A component consists of a modified urea-formaldehyde resin A component,some cement,and some water.The B component is an alkaline coagulant.An orthogonal test of four factors at three levels showed that gel time increased with increased water content and with urea-formaldehyde resin content.Gel time decreased at increased levels of alkaline coagulant.The A component of this new composite grout is stable over time.A mixed cross-over test showed that as the volume ratio of A to B increases the gel time falls at first but then increases.The solid strength decreases with increasing levels of the B component.The solid strength increases over time and becomes stable by the 28th day after mixing.The viscosity increases with increasing levels of resin A component.The increase is exponential and may be fit to:l = 8.162e0.0286x.Duan Hongfei Jiang Zhenquan Zhu Shuyun Yao Pu Sun Qiang 2012International Journal of Mining Science and Technology2012,22,2:22
9Molecular mechanisms of diabetic coronary dysfunction due to large conductance Ca2+-activated K+ channel impairment显示文摘WANG Ru-xing SHI Hai-feng CHAI Qiang WU Ying SUN Wei JI Yuan YAO Yong LI Ku-lin ZHANG Chang-ying ZHENG Jie GUO Su-xia LI Xiao-rong LU Tong 2012Chinese Medical Journal2012,,14:21
10One-step generation of complete gene knockout mice and monkeys by CRISPR/Cas9-mediated gene editing with multiple sgRNAs显示文摘CRISPR/Cas9 系统是一个有效编辑基因的方法,但是编辑基因的动物的多数显示出 mosaicism,与编辑仅仅在房间的部分发生。这里,我们证明那单个基因或多重基因能被 Cas9 mRNA 和多重邻近的单个指南的 RNA 的 zygotic 注射完全在老鼠和猴子胚胎击倒(spaced 10-200 bp 分开) 指向仅仅一把单个钥匙每基因的 exon。个别地在 Y 染色体上跟随八基因的指向的删除的 F0 老鼠的 Phenotypic 分析在产生猛烈老鼠表明了这条途径的坚韧性。重要地,这条途径在高效率交付完全的基因大美人(Arntl 上的 100% 并且 91% 在 Prrt2 上) 在猴子胚胎。最后,我们能在一个单个步骤产生一只完全的 Prrt2 猛烈猴子,表明在很快建立编辑基因的猴子模型的这条途径的实用性。Erwei Zuo Yi-Jun Cai Kui Li Yu Wei Bang-An Wang Yidi Sun Zhen Liu Jiwei Liu Xinde Hu Wei Wei Xiaona Huo Linyu Shi Cheng Tang Dan Liang Yan Wang Yan-Hong Nie Chen-Chen Zhang Xuan Yao Xing Wang Changyang Zhou Wenqin Ying Qifang Wang Ren-Chao Chen Qi Shen Guo-Liang Xu Jinsong Li Qiang Sun Zhi-Qi Xiong Hui Yang 2017Cell Research2017,27,7:21
11Blocking the recruitment of naive CD4+ T cells reverses immunosuppression in breast cancer显示文摘渗入肿瘤的 Tregs 的起源,肿瘤免疫力的抑制的批评调停人,是不清楚的。这里,,我们证明在人的乳癌的渗入肿瘤的天真的 CD4 + T 房间和 Tregs 有重叠 TCR 全部剧目几乎别与传播 Tregs 重叠,建议 intratumoral Tregs 主要在 situ 而非从招募的 Tregs 从天真的 T 房间发展。而且,许多天真的 CD4 + T 房间和 Tregs 密切被相关,两个显示的穷人为乳癌病人的预后。天真的 CD4 + T 房间与许多生产 CCL18 巨噬细胞成比例遵守肿瘤片。而且,采纳地转移的人的天真的 CD4 + T 房间以一种 CCL18 依赖的方式渗入人的乳癌 orthotopic 异种皮移植。在在人性化的鼠标的人的乳癌异种皮移植,由将 PITPNM3 的表达式击倒堵住天真的 CD4 + T 房间的招募进肿瘤, CCL18 受体,显著地减少 intratumoral Tregs 并且禁止肿瘤前进。这些调查结果建议那个乳房渗入肿瘤的 Tregs 从在 situ 区分进 Tregs 的传播天真的 CD4 + T 房间的趋化性产生。由防碍 CCL18 的 PITPNM3 识别禁止天真的 CD4 + T 房间招募进肿瘤可以是为 anticancer 免疫疗法的吸引人的策略。Shicheng Su Jianyou Liao Jiang Liu Di Huang Chonghua He Fei Chen LinBing Yang Wei Wu Jianing Chen Ling Lin Yunjie Zeng Nengtai Ouyang Xiuying Cui Herui Yao Fengxi Su Jian-dong Huang Judy Lieberman Qiang Liu Erwei Song 2017Cell Research2017,27,4:19
12Role of Ni(NO_3)_2 in the preparation of a magnetic coal-based activated carbon显示文摘The role of Ni(NO3)2 in the preparation of a magnetic activated carbon is reported in this paper.Magnetic coal-based activated carbons(MCAC) were prepared from Taixi anthracite with low ash content in the presence of Ni(NO3)2.The MCAC materials were characterized by a vibrating sample magnetometer(VSM),X-ray diffraction(XRD),a scanning electric microscope(SEM),and by N2 adsorption.The cylindrical precursors and derived char were also subjected to thermogravimetric analysis to compare their behavior of weight losses during carbonization.The results show that MCAC has a larger surface area(1074 m2/g) and a higher pore volume(0.5792 cm3/g) with enhanced mesopore ratio(by about 10%).It also has a high saturation magnetization(1.6749 emu/g) and low coercivity(43.26 Oe),which allows the material to be magnetically separated.The MCAC is easily magnetized because the nickel salt is converted into Ni during carbonization and activation.Metallic Ni has a strong magnetism on account of electrostatic interaction.Added Ni(NO3)2 catalyzes the carbonization and activation process by accelerating burn off of the carbon,which contributes to the development of mesopores and macropores in the activated carbon.ZhangJun Xie Qiang Liu Juan Yang Mingshun Yao Xing 2011Mining Science and Technology2011,21,4:17
13Pore-structure-mediated hierarchical SAPO-34:Facile synthesis,tunable nanostructure,and catalysis applications for the conversion of dimethyl ether into olefins显示文摘Hierarchical cross-like SAPO-34 catalysts with different pore size distributions were obtained via hydrothermal synthesis with polyethylene glycol(PEG) as the mesopore-generating agent.The hierarchical SAPO-34 molecular sieves were characterized using X-ray diffraction,scanning electron microscopy,N_2adsorption-desorption,thermogravimetric analysis,and temperature-programmed NH_3 desorption.The cross-like SAPO-34 catalysts exhibited enriched multi-porosity,and the sizes of their mesopores ranged from 10 to 50 nm.Both the mesoporous structures and morphologies of the hierarchical SAPO-34 could be further tuned through adjustments of the amount of PEG used.The as-obtained SAPO-34 showed dramatic catalytic performance in the conversion of dimethyl ether into olefins.A maximum selectivity of olefins of 96%was achieved,which was attributed to the rapid transport of the reactants and products in zeolitic micropores through mesopores.Yu Cui Qiang Zhang Jie He Yao Wang Fei Wei 2013Particuology2013,11,4:17
14New progress in endoscopic treatment of esophageal diseases显示文摘The technique of endoscopic submucosal dissection(ESD),which was developed for en bloc resection of large lesions in the stomach,has been widely accepted for the treatment of the entire gastrointestinal tract.Many minimally invasive endoscopic therapies based on ESD have been developed recently.Endoscopic submucosal excavation,submucosal tunneling endoscopic resection and laparoscopic-endoscopic cooperative surgery have been used to remove submucosal tumors,especially tumors which originate from the muscularis propria of the digestive tract.Peroral endoscopic myotomy has recently been described as a scarless and less invasive surgical myotomy option for the treatment of achalasia.Patients benefit from minimally invasive endoscopic therapy.This article,in the highlight topic series,provides detailed information on the indications and treatments for esophageal diseases.Ping-Hong Zhou Qiang Shi Yun-Shi Zhong Li-Qing Yao 2013World Journal of Gastroenterology2013,19,41:16
15Adipose-derived mesenchymal stem cell transplantation promotes adult neurogenesis in the brains of Alzheimer's disease mice显示文摘In the present study,we transplanted adipose-derived mesenchymal stem cells into the hippocampi of APP/PS1 transgenic Alzheimer’s disease model mice.Immunofluorescence staining revealed that the number of newly generated(BrdU+)cells in the subgranular zone of the dentate gyrus in the hippocampus was significantly higher in Alzheimer’s disease mice after adipose-derived mesenchymal stem cell transplantation,and there was also a significant increase in the number of BrdU+/DCX+neuroblasts in these animals.Adipose-derived mesenchymal stem cell transplantation enhanced neurogenic activity in the subventricular zone as well.Furthermore,adipose-derived mesenchymal stem cell transplantation reduced oxidative stress and alleviated cognitive impairment in the mice.Based on these findings,we propose that adipose-derived mesenchymal stem cell transplantation enhances endogenous neurogenesis in both the subgranular and subventricular zones in APP/PS1 transgenic Alzheimer’s disease mice,thereby facilitating functional recovery.Yufang Yan Tuo Ma Kai Gong Qiang Ao Xiufang Zhang Yao Gong 2014Neural Regeneration Research2014,9,8:16
16Efficacy of postoperative antiviral combined transcatheter arterial chemoembolization therapy in prevention of hepatitis B-related hepatocellular carcinoma recurrence显示文摘YAN Qiang NI Jun ZHANG Guo-lei YAO Xing YUAN Wen-bin ZHOU Lin ZHENG Shu-sen 2013Chinese Medical Journal2013,,5:16
17Influence of flue gas cleaning system on characteristics of PM_(2.5)emission from coal-fired power plants显示文摘This study investigated the influence of precipitators and wet flue gas desulfurization equipment on characteristics of PM_(2.5)emission from coal-fired power stations.We measured size distribution and removal efficiencies,including hybrid electrostatic precipitator/bag filters(ESP/BAGs)which have rarely been studied.A bimodal distribution of particle concentrations was observed at the inlet of each precipitator.After the precipitators,particle concentrations were significantly reduced.Although a bimodal distribution was still observed,all peak positions shifted to the smaller end.The removal efficiencies of hybrid ESP/BAGs reached 99%for PM_(2.5),which is considerably higher than those for other types of precipitators.In particular,the influence of hybrid ESP/BAG operating conditions on the performance of dust removal was explored.The efficiency of hybrid ESP/BAGs decreased by 1.9%when the first electrostatic field was shut down.The concentrations and distributions of particulate matter were also measured in three coal-fired power plants before and after desulfurization devices.The results showed diverse removal efficiencies for different desulfurization towers.The reason for the difference requires further research.We estimated the influence of removal technology for particulate matter on total emissions in China.Substituting ESPs with hybrid ESP/BAGs could reduce the total emissions to 104.3 thousand tons,with 47.48 thousand tons of PM_(2.5).Ao Wang Qiang Song Gongming Tu Hui Wang Yong Yue Qiang Yao 2014International Journal of Coal Science & Technology2014,1,1:16
18S-1-based vs non-S-1-based chemotherapy in advanced gastric cancer: A meta-analysis显示文摘AIM: To assess the efficacy and tolerability of S-1-based vs non-S-1-based chemotherapy in advanced gastric cancer(AGC). METHODS: We extracted reported endpoints, including overall survival(OS), progression-free survival(PFS), time-to-treatment failure(TTF), objective response rate(ORR) and adverse effects, from randomized controlled trials identified in PubMed, the Cochrane library, Science Direct, EMBASE and American Society of Clinical Oncology meetings. Stata software was used to calculate the pooled values.RESULTS: Seven randomized controlled trials involving 2176 patients were included in this meta-analysis. Compared to non-S-1-based regimens, the use of S-1-based regimens were associated with an increase in ORR(RR = 1.300; 95%CI: 1.028-1.645); OS(HR = 0.89; 95%CI: 0.81-0.99; P = 0.025), TTF(HR = 0.83; 95%CI: 0.75-0.92; P = 0.000), and a lower risk of febrile neutropenia(RR = 0.225; P = 0.000) and stomatitis(RR = 0.230; P = 0.032). OS, PFS and TTFwere prolonged, especially in the Asian population. In subgroup analysis, statistically significant increases in ORR(RR = 1.454; P = 0.029), OS(HR = 0.895; P = 0.041) and TTF(HR = 0.832; P = 0.000) were found when S-1-based chemotherapy was compared to 5-fluorouracil(5-FU)-based chemotherapy. The incidence of leukopenia(RR = 0.584; P = 0.002) and stomatitis(RR = 0.230; P = 0.032) was higher in the 5-FU-based arm. S-1-based regimens had no advantage in ORR, OS, PFS, TTF and grade 3 or 4 adverse events over capecitabine-based regimens. CONCLUSION: S-1-based chemotherapy may be a good choice for AGC because of longer survival times, better tolerance and more convenient use.Jian Yang Yan Zhou Ke Min Qiang Yao Chun-Ni Xu 2014World Journal of Gastroenterology2014,20,33:15
19Rapid report of the 8 January 2022 M_(S)6.9 Menyuan earthquake,Qinghai,China显示文摘The M_(S)6.9 Menyuan earthquake in Qinghai Province,west China is the largest earthquake by far in 2022.The earthquake occurs in a tectonically active region,with a background b-value of 0.87 within 100 km of the epicenter that we derived from the unified catalog produced by China Earthquake Networks Center since late 2008.Field surveys have revealed surface ruptures extending 22 km along strike,with a maximum ground displacement of 2.1 m.We construct a finite fault model with constraints from In SAR observations,which showed multiple fault segments during the Menyuan earthquake.The major slip asperity is confined within 10 km at depth,with the maximum slip of 3.5 m.Near real-time back-projection results of coseismic radiation indicate a northwest propagating rupture that lasted for~10 s.Intensity estimates from the back-projection results show up to a Mercalli scale of IX near the ruptured area,consistent with instrumental measurements and the observations from the field surveys.Aftershock locations(up to January 21,2022)exhibit two segments,extending to~20 km in depth.The largest one reaches M_(S)5.3,locating near the eastern end of the aftershock zone.Although the location and the approximate magnitude of the mainshock had been indicated by previous studies based on paleoearthquake records and seismic gap,as well as estimated stressing rate on faults,significant surfacebreaching rupture leads to severe damage of the high-speed railway system,which poses a challenge in accurately assessing earthquake hazards and risks,and thus demands further investigations of the rupture behaviors for crustal earthquakes.Hongfeng Yang Dun Wang Rumeng Guo Mengyu Xie Yang Zang Yue Wang Qiang Yao Chuang Cheng Yanru An Yingying Zhang 2022Earthquake Research Advances2022,2,1:14
20Effect of advanced age on plasma homocysteine levels and its association with ischemic stroke in non-valvular atrial fibrillation显示文摘BackgroundElevated homocysteine (Hcy ) 被报导了在 atrial 与心血管的事件被联系纤维性颤动(AF ) 病人,当在 AF 的血浆 Hcy 的年龄相关的表示模式仍然保持未知时。学习被瞄准与非瓣膜的 AF 在 2562 个连续病人全部的非瓣膜的 AF patients.MethodsA 与 ischemic 击在血浆 Hcy 层次和它的协会上调查先进年龄的效果, 535 控制被注册并且把年龄组划分了成六。血浆 Hcy 层次在不同年龄组之中被分析,并且 Hcy 上的先进年龄的效果是 investigated.ResultsPlasma Hcy 层次没证明在组之中的任何差别在 65 年下面变老,当它 65-74 年并且超过 75 年在病人严厉地增加了时(15.Yan YAO Li-Jian GAO Yong ZHOU Jing-Hua ZHAO Qiang LV Jian-Zeng DONG Mei-Sheng SHANG 2017Journal of Geriatric Cardiology2017,14,12:13
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