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| 1 | Role of needle knife assisted ampullary biopsy in the diagnosis of periampullary carcinomaAbstractAIM:Tostudytheroleofneedleknifeassistedampul-显示文摘AIM:To study the role of needle knife assisted ampullary biopsy in the diagnosis of periampullary carcinoma.METHODS:In this study the authors retrospectively analyzed clinical records of patients with periampullary tumors diagnosed by ampullary biopsy taken after needle knife papillotomy in whom surface ampullary biopsies were non contributory.RESULTS:Between January 2008 and December 2010,38 patients with periampullary tumors were seen by us and initial side viewing endoscopy with surface biopsy from the papilla was positive for malignancy in 25 patients.Thirteen patients with a negative surface biopsy for malignancy underwent a repeat ampullary biopsy following needle knife papillotomy.There were 8(61.5%)males and 5(38.5%)females.The most common presenting symptom was jaundice(100%),followed by fever(46.2%),melena(38.5%),abdominal pain(30.8%)and weight loss(30.8%).All the patients had hyperbilirubinemia with a mean ± SD serum bilirubin of(11.2 ± 1.9)mg/dL(normal value <1 mg%)and the mean ± SD serum alkaline phosphatase was(288.0 ± 94.3)IU/L(normal value < 129 IU/L).Serum CA 19.9 level estimation was done in 11 patients;it was elevated(cut off value > 70.5 IU/L)in all of them with a median of 1200 IU/L(inter quartile range 274-3500).Side viewing endoscopy showed a bulky papilla in all of them.Adequate tissue was obtained in all of the 13 patients for histological evaluation;12 of the 13 patients were reported to have adenocarcinoma while one patient had adenoma.There were no complications from the needle knife papillotomy in any of the patients.CONCLUSION:Needle knife assisted ampullary biopsy appears to be a safe and effective diagnostic modality for periampullary carcinoma. | Mohd Talha Noor Kim Vaiphei Birinder Nagi Kartar Singh | 2011 | World Journal of Gastrointestinal Endoscopy2011，3，11： | 2 |
| 2 | Roles of syndecan-1, bcl6 and p53 in diagnosis and prognostication of immunoproliferative small intestinal disease显示文摘瞄准:在 immunoproliferative 的诊断和预知评估 syndecan-1, bcl6 和 p53 的角色小肠的疾病(IPSID ) 并且学习 kappa (kappa ) 和人字缝尖(人字缝尖) 的侧面轻链和 IgA 重链。方法:学习由 IPSID 的 11 个盒子和包括了 11 正常肠粘膜和回肠的 11 高等级 B 房间淋巴瘤的控制的类似的数字组成了。分析的参数包括了临床的侧面,生物化学并且另外的实验室调查,放射线学并且组织检查所见包括免疫组织化学。结果:所有 IPSID 箱子有可论证的浆液 IgA 重链和重粘膜血浆房间渗入。根据 Galian 的组织学的阶段,有有舞台 A 的 4 个病人并且 7 与舞台 B。kappa 和人字缝尖轻链在 7 个病人是过去表示的;1 舞台 A H pylori 的耐心的有的 H pylori 积极的活跃胃炎和根除导致了疾病宽恕。舞台 A 活体检视为 syndecan-1 有更高的表示,当舞台 B 为 bcl6 和 p53 有更高的表示时。Syndecan-1, kappa 和人字缝尖轻链和 IgA 重链与 bcl6 和 p53 显示出反的关系。所有病人与 doxycycline 被对待。砍政体在得了坦率的淋巴瘤的 5 个病人被增加。三由于广泛的机关渗入死于疾病。结论:象 syndecan-1, kappa 和人字缝尖轻链和 IgA 重链一样的某些免疫标记能具有在识别早阶段 IPSID 的许多帮助。舞台 B IPSID 比上演 IPSID 为 bcl6 和 p53 显示出更高的表示。bcl6 和 p53 表情与一个更多的病沉重期舞台和好攻击的瘤行为相关。 | Kim Vaiphei Neeraj Kumari Saroj Kant Sinha Usha Dutta Birinder Nagi Kusum Joshi Kartar Singh | 2006 | World Journal of Gastroenterology2006，12，22： | 2 |
| 3 | 4-1BBL ligand induces cell division,sustains survival,and enhances effector function of CD4 and CD8 T cells with similar efficacy显示文摘 | Peggy Lau Birinder Ghumman | 2001 | J Immunol2001，167，： | 1 |
| 4 | Sequential Endoscopic Papillary Balloon Dilatation Following Limited Sphincterotomy for Common Bile Duct Stones显示文摘 | Rakesh Kochhar Usha Dutta Rajat Shukla Birinder Nagi Kartar Singh Jai D. Wig | 2009 | Digestive Diseases and Sciences2009，，7： | 1 |
| 5 | Clinical, Biochemical, and Radiologic Parameters at Admission Predicting Formation of a Pseudocyst in Acute Pancreatitis显示文摘 | Kuchhangi Sureshchandra Poornachandra Deepak Kumar Bhasin Birinder Nagi Saroj Kant Sinha Surinder Singh Rana Nusrat Shafiq Katarina Greer Rajesh Gupta Mandeep Kang Samir Malhotra Kartar Singh | 2011 | Journal of Clinical Gastroenterology2011，，2： | 1 |
| 6 | Sequential Endoscopic Papillary Balloon Dilatation Following Limited Sphincterotomy for Common Bile Duct Stones显示文摘 | Rakesh Kochhar Usha Dutta Rajat Shukla Birinder Nagi Kartar Singh Jai D. Wig | 2009 | Digestive Diseases and Sciences2009，，7： | 1 |
| 7 | Sequential Endoscopic Papillary Balloon Dilatation Following Limited Sphincterotomy for Common Bile Duct Stones显示文摘 | Rakesh Kochhar Usha Dutta Rajat Shukla Birinder Nagi Kartar Singh Jai D. Wig | 2009 | Digestive Diseases and Sciences2009，，7： | 1 |
| 8 | Sequential Endoscopic Papillary Balloon Dilatation Following Limited Sphincterotomy for Common Bile Duct Stones显示文摘 | Rakesh Kochhar Usha Dutta Rajat Shukla Birinder Nagi Kartar Singh Jai D. Wig | 2009 | Digestive Diseases and Sciences2009，，7： | 1 |
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