|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | KCNE3 R53H substitution in familial atrial fibrillation显示文摘 | ZHANG Dai-fu LIANG Bo LIN Jie LIU Ban ZHOU Qin-shu YANG Yi-qing | 2005 | Chinese Medical Journal2005，，20： | 18 |
| 2 | Genome-wide DNA methylation profiles in Tibetan and Yorkshire pigs under highaltitude hypoxia显示文摘Background: Tibetan pigs, which inhabit the Tibetan Plateau, exhibit distinct phenotypic and physiological characteristics from those of lowland pigs and have adapted well to the extreme conditions at high altitude.However, the genetic and epigenetic mechanisms of hypoxic adaptation in animals remain unclear.Methods: Whole-genome DNA methylation data were generated for heart tissues of Tibetan pigs grown in the highland(TH, n = 4) and lowland(TL, n = 4), as well as Yorkshire pigs grown in the highland(YH, n = 4) and lowland(YL, n = 4), using methylated DNA immunoprecipitation sequencing.Results: We obtained 480 million reads and detected 280679, 287224, 259066, and 332078 methylation enrichment peaks in TH, YH, TL, and YL, respectively. Pairwise TH vs. YH, TL vs. YL, TH vs. TL, and YH vs. YL comparisons revealed6829, 11997, 2828, and 1286 differentially methylated regions(DMRs), respectively. These DMRs contained 384, 619,192, and 92 differentially methylated genes(DMGs), respectively. DMGs that were enriched in the hypoxia-inducible factor 1 signaling pathway and pathways involved in cancer and hypoxia-related processes were considered to be important candidate genes for high-altitude adaptation in Tibetan pigs.Conclusions: This study elucidates the molecular and epigenetic mechanisms involved in hypoxic adaptation in pigs and may help further understand human hypoxia-related diseases. | Bo Zhang Dongmei Ban Xiao Gou Yawen Zhang Lin Yang Yangzom Chamba Hao Zhang | 2019 | Journal of Animal Science and Biotechnology2019，10，2： | 6 |
| 3 | Identification of differentially expressed genes in mouse hepatocarcinoma ascites cell line with low potential of lymphogenous metastasis显示文摘AIM: To identify genes differentially expressed in mouse hepatocarcinoma ascites cell line with low potential of lymphogenous metastasis. METHODS: A subtracted cDNA library of mouse hepatocarcinoma cell line with low potential of lympho- genous metastasis Hca-P and its synogenetic cell line Hca-F with high metastatic potential was constructed by suppression subtracted hybridization (SSH) method. The screened clones of the subtracted library were sequenced and GenBank homology search was performed. RESULTS: Fifteen differentially expressed cDNA fragments of Hca-P were obtained which revealed 8 known genes, 4 expressed sequence tags (ESTs) and 3 cDNAs showed no homology. CONCLUSION: Tumor metastasis is an incident involving multiple genes. SSH is a useful technique to detect differentially expressed genes and an effective method to clone novel genes. | Xiao-Nan Cui Jian-Wu Tang Li Hou Bo Song Li-Ying Ban | 2006 | World Journal of Gastroenterology2006，12，42： | 5 |
| 4 | Real-time visualization of 3D city models at street-level based on visual saliency显示文摘Street-level visualization is an important application of 3D city models.Challenges to street-level visualization include the cluttering of buildings due to fine detail and visualization performance.In this paper,a novel method is proposed for streetlevel visualization based on visual saliency evaluation.The basic idea of the method is to preserve these salient buildings in a scene while removing those that are non-salient.The method can be divided into pre-processing procedures and real-time visualization.The first step in pre-processing is to convert 3D building models at higher Levels of Detail(Lo Ds) into LoD 1 models with simplified ground plans.Then,a number of index viewpoints are created along the streets; these indices refer to both the position and the direction of each street site.A visual saliency value is computed for each building,with respect to the index site,based on a visual difference between the original model and the generalized model.We calculate and evaluate three methods for visual saliency:local difference,global difference and minimum projection area.The real-time visualization process begins by mapping the observer to its closest indices.The street view is then generated based on the building information stored in those indexes.A user study shows that the local visual saliency method performs better than do the global visual saliency,area and image-based methods and that the framework proposed in this paper may improve the performance of 3D visualization. | MAO Bo BAN YiFang Lars HARRIE | 2015 | Science China Earth Sciences2015，58，3： | 5 |
| 5 | Corrigendum to Anthropogenic emission inventories in China:a review显示文摘In the Figure 4 of ‘Anthropogenic emission inventories in China:a review'(National Science Review,Volume 4,Issue 6, 2017,Pages 834-866,doi:10.1093/nsr/nwx150),the data for the MEIC vl.2 was incorrectly plotted.The corrected version of Figure 4 is presented below. | Meng Li Huan Liu Guannan Geng Chaopeng Hong Fei Liu Yu Song Ban Tong Bo Zheng Hongyang Cui Hanyang Man Qiang Zhang Kebin He | 2018 | National Science Review2018，5，4： | 5 |
| 6 | Directional Growth of Tin Crystals Controlled by Combined Solute Concentration Gradient Field and Static Magnetic Field显示文摘A new method was introduced to achieve directional growth of Sn crystals. Microstructures in liquid(Pb)/liquid(Sn) diffusion couples were investigated under various static magnetic fields. Results show that the β-Sn crystals mainly reveal an irregular dendritic morphology without or with a relatively low static magnetic field(B0.3 T). When the magnetic field is increased to 0.5 T, the β-Sn dendrites close to the final stage of growth begin to show some directional character. With a further increase in the magnetic field to a higher level(0.8–5 T), the β-Sn dendrites have an enhanced directional growth character, but the dendrites show a certain deflection. As the magnetic field is increased to 12 T, the directional growth of the β-Sn dendrites in the center of the couple is severely destroyed. The mechanism of the directional growth of the β-Sn crystals and the deflection of the β-Sn crystals with the application of static magnetic field was tentatively discussed. | Lei Li Bo Xu Wei-Ping Tong Hui Zhang Chun-Yan Ban Li-Zi He Zhi-Hao Zhao Yu-Bo Zuo Qing-Feng Zhu Jian-Zhong Cui | 2015 | Acta Metallurgica Sinica(English Letters)2015，28，6： | 3 |
| 7 | Effects of Multiple Cleaning and Disinfection Interventions on Infectious Diseases in Children: A Group Randomized Trial in China显示文摘Objective To assess the effectiveness of multiple cleaning and disinfection interventions in the homes and kindergartens, in reducing gastrointestinal and respiratory illnesses of children. Methods From October 2010 to September 2011, we performed a prospective, controlled study in China. 408 children under 5 years old were recruited and group randomized into intervention and control groups. Families and kindergartens in the intervention group were provided with antibacterial products for hand hygiene and surface cleaning or disinfection for one year. Each child's illness symptoms and sick leave were recorded every day. Results A total of 393 children completed the study, with similar baseline demographics in each of the 2 groups. Except for abdominal pain, the odds of symptoms(fever, cough and expectoration, runny nose and nasal congestion, diarrhea), illness(acute respiratory illness and gastrointestinal illness), and sick leave per person each month were significantly reduced by interventions. The rates of fever, diarrhea, acute respiratory illness, gastrointestinal illness and sick leave per person per year were significantly decreased as well. Conclusion Not only the acute respiratory and gastrointestinal illness but the sick leave rate in children were significantly reduced by multiple interventions. | BAN Hai Qun LI Tao SHEN Jin LI Jin PENG Pin Zhang YE Heng Ping ZHANG Liu Bo | 2015 | Biomedical and Environmental Sciences2015，28，11： | 2 |
| 8 | Population structure and genetic diversity distribution in wild and cultivated populations of the traditional Chinese medicinal plant Magnolia officinalis subsp. biloba (Magnoliaceae)显示文摘 | Jingsheng He Ling Chen Ying Si Bo Huang Xiaoquan Ban Youwei Wang | 2009 | Genetica2009，，2： | 1 |
| 9 | Hepatoprotective and anfioxidant activity of ethanolic extracts of edible lotus (Nelumbo nucifera Gaertn) leaves显示文摘 | HUANG Bo BAN Xiaoquan HE Jingsheng | 2010 | Food Chemistry2010，120，3： | 1 |
| 10 | Generalization of 3D building texture using image compression and multiple representation data structure显示文摘 | Bo Mao Yifang Ban | 2013 | ISPRS Journal of Photogrammetry and Remote Sensing2013，79，： | 1 |
| 11 | Long-term ethanol exposure inhibits glucose transporter 4 expression via an AMPK-dependent pathway in adipocytes显示文摘 | Li FENG Yong-feng SONG Qing-bo GUAN Hong-jun LIU Bo BAN Hai-xin DONG Xiao-lei HOU Kok-onn LEE Ling GAO Jia-jun ZHAO | 2010 | Acta Pharmacologica Sinica2010，31，3： | 1 |
| 12 | Antioxidant activity of bovine and porcine meat treated with extracts from edible lotus (Nelumbo nucifera) rhizome knot and leaf显示文摘 | HUANG Bo HE Jingsheng BAN Xiaoquan | 2011 | Meat Science2011，87，1： | 1 |
| 13 | Chemical composition and antifungal activity of essential oil from Cicuta virosa L. var. latisecta Celak显示文摘 | Jun Tian Xiaoquan Ban Hong Zeng Jingsheng He Bo Huang Youwei Wang | 2011 | International Journal of Food Microbiology2011，，2： | 1 |
| 14 | Chemical composition and antifungal activity of essential oil from Cicuta virosa L. var. latisecta Celak显示文摘 | Jun Tian Xiaoquan Ban Hong Zeng Jingsheng He Bo Huang Youwei Wang | 2011 | International Journal of Food Microbiology2011，，2： | 1 |
| 15 | Generalization of 3D Building Texture Using Image Compression and Multiple Representation Data Structure显示文摘 | Bo Mao Yifang Ban | 2013 | ISPRS Journal of Photogrammetry and Remote Sensing2013，79，： | 1 |
| 16 | The control of Aspergillus flavus with Cinnamomum jensenianum Hand.-Mazz essential oil and its potential use as a food preservative显示文摘 | Jun Tian Bo Huang Xiuli Luo Hong Zeng Xiaoquan Ban Jingsheng He Youwei Wang | 2011 | Food Chemistry2011，，3： | 1 |
| 17 | A phase III randomized,double-blind,placebo-controlled trial of the denosumab biosimilar QL1206 in postmenopausal Chinese women with osteoporosis and high fracture risk显示文摘The current study evaluated the efficacy and safety of a denosumab biosimilar,QL1206(60 mg),compared to placebo in postmenopausal Chinese women with osteoporosis and high fracture risk.At 31 study centers in China,a total of 455 postmenopausal women with osteoporosis and high fracture risk were randomly assigned to receive QL1206(60 mg subcutaneously every 6 months)or placebo.From baseline to the 12-month follow-up,the participants who received QL1206 showed significantly increased bone mineral density(BMD)values(mean difference and 95%CI)in the lumbar spine:4.780%(3.880%,5.681%),total hip:3.930%(3.136%,4.725%),femoral neck 2.733%(1.877%,3.589%)and trochanter:4.058%(2.791%,5.325%)compared with the participants who received the placebo.In addition,QL1206 injection significantly decreased the serum levels of C-terminal crosslinked telopeptides of type 1 collagen(CTX):−77.352%(−87.080%,−66.844%),and N-terminal procollagen of type l collagen(P1NP):−50.867%(−57.184%,−45.217%)compared with the placebo over the period from baseline to 12 months.No new or unexpected adverse events were observed.We concluded that compared with placebo,QL1206 effectively increased the BMD of the lumbar spine,total hip,femoral neck and trochanter in postmenopausal Chinese women with osteoporosis and rapidly decreased bone turnover markers.This study demonstrated that QL1206 has beneficial effects on postmenopausal Chinese women with osteoporosis and high fracture risk. | Hao Zhang Jie-mei Gu Ai-jun Chao Qun Cheng Dong-hui Teng Jin-ming Yu Bing-wu Wang Ya-nan Huo Li Mao Qiu Zhang Hong Yang Shi-gui Yan Ke-qin Zhang Xue-ling Zhao Hua Lin Yu Pei Zhong Yuan Ru-chun Dai Liang He Li Chen Yong-feng Su Zhong-liang Deng Li You Bo Ban Mei Zhu You-liang Cao Yi-kun Zhu Zhi-jun Li Zhi Zhang Cheng-qing Yi Yi-bing Lu Guang Wang Cui-cui Han Zhen-jiang Wang Xian-xing Li Zhen-lin Zhang | 2023 | Acta Pharmacologica Sinica2023，44，2： | 1 |
| 18 | Microbial Presence on Kitchen Dishcloths in Chinese Housholds显示文摘To study the microbiological contamination of kitchen dishcloths in Chinese housholds,1010‘in-use’kitchen dishcloths were collected from residential premises in Beijing and Shanghai,and they were sent to the laboratory for microbiological quality analysis.The aerobic plate counts for dishcloths were 10-109 cfu/cm2 in the range of | SHEN Jin ZHAO Bin Xiu LI Tao BAN Hai Qun TIAN Liang GE Yi Lin CHEN Tai Yao LI Shi Yue ZHANG Liu Bo | 2014 | Biomedical and Environmental Sciences2014，27，12： | 0 |
| 19 | Development and validation of a nomogram for predicting metachronous peritoneal metastasis in colorectal cancer:A retrospective study显示文摘BACKGROUND Peritoneal metastasis(PM)after primary surgery for colorectal cancer(CRC)has the worst prognosis.Prediction and early detection of metachronous PM(m-PM)have an important role in improving postoperative prognosis of CRC.However,commonly used imaging methods have limited sensitivity to detect PM early.We aimed to establish a nomogram model to evaluate the individual probability of m-PM to facilitate early interventions for high-risk patients.AIM To establish and validate a nomogram model for predicting the occurrence of m-PM in CRC within 3 years after surgery.METHODS We used the clinical data of 878 patients at the Second Hospital of Jilin University,between January 1,2014 and January 31,2019.The patients were randomly divided into training and validation cohorts at a ratio of 2:1.The least absolute shrinkage and selection operator(LASSO)regression was performed to identify the variables with nonzero coefficients to predict the risk of m-PM.Multivariate logistic regression was used to verify the selected variables and to develop the predictive nomogram model.Harrell’s concordance index,receiver operating characteristic curve,Brier score,and decision curve analysis(DCA)were used to evaluate discrimination,distinctiveness,validity,and clinical utility of this nomogram model.The model was verified internally using bootstrapping method and verified externally using validation cohort.RESULTS LASSO regression analysis identified six potential risk factors with nonzero coefficients.Multivariate logistic regression confirmed the risk factors to be independent.Based on the results of two regression analyses,a nomogram model was established.The nomogram included six predictors:Tumor site,histological type,pathological T stage,carbohydrate antigen 125,v-raf murine sarcoma viral oncogene homolog B mutation and microsatellite instability status.The model achieved good predictive accuracy on both the training and validation datasets.The C-index,area under the curve,and Brier scores were 0.796,0.796[95%confidence interval(CI)0.735-0.856],and 0.081 for the training cohort and 0.782,0.782(95%CI 0.690-0.874),and 0.089 for the validation cohort,respectively.DCA showed that when the threshold probability was between 0.01 and 0.90,using this model to predict m-PM achieved a net clinical benefit.CONCLUSION We have established and validated a nomogram model to predict m-PM in patients undergoing curative surgery,which shows good discrimination and high accuracy. | Bo Ban An Shang Jian Shi | 2023 | World Journal of Gastrointestinal Oncology2023，15，1： | 0 |
| 20 | Efficacy of staple line reinforcement by barbed suture for preventing anastomotic leakage in laparoscopic rectal cancer surgery显示文摘BACKGROUND Anastomotic leakage(AL) is a severe complication in rectal cancer surgery.Various methods, including intracorporeal reinforcing suturing, have been used to reduce the incidence of AL. However, little is known about the efficacy of staple-line reinforcement by barbed suture for preventing AL.AIM To evaluate the efficacy of staple-line reinforcement using barbed suture for preventing AL in laparoscopic surgery for rectal cancer.METHODS We retrospectively reviewed the clinical datum of 319 patients undergoing laparoscopic low anterior resection combined with double stapling technique between May 1, 2017 and January 31, 2021. All surgeries were performed by the same surgical team specializing in colorectal surgery. Patients were divided into two groups depending on whether they received reinforcing sutures. Patients’ baseline characteristics did not show any significant difference between the two groups. We analyzed patient-, tumor-, as well as surgery-related variables using univariate and multivariate logistic analyses.RESULTS There were 168 patients in the reinforcing suture group and 151 patients in the non-reinforcing suture group. AL occurred in 25 cases(7.8%). Its incidence was significantly higher in the non-reinforcing suture group than in the reinforcing suture group(4.8% vs 11.3%, P = 0.031). The multivariate analyses demonstrated that the tumor site, tumor size and presence of staple-line reinforcement were independent risk factors for AL. We divided these patients into two risk groups based on the combination of tumor site and tumor size. Patients without any risk factor were assigned to the low-risk group(n = 177), whereas those having one or two risk factors were assigned to the high-risk group(n = 142). In the high-risk group, the AL incidence considerably decreased in the reinforcing suture group compared with that in the non-reinforcing suture group(P = 0.038). Nonetheless, no significant difference was found in the low-risk group between the two groups.CONCLUSION Staple-line reinforcement by barbed suture may decrease the incidence of AL. A large-scale prospective randomized controlled trial is needed for evaluating the efficacy of staple-line reinforcement for preventing AL. | Bo Ban An Shang Jian Shi | 2022 | World Journal of Gastrointestinal Surgery2022，14，8： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员