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| 1 | Osteoprotegerin: A Novel Secreted Protein Involved in the Regulation of Bone Density显示文摘 | W.S Simonet D.L Lacey C.R Dunstan M Kelley M.-S Chang R Lüthy H.Q Nguyen S Wooden L Bennett T Boone G Shimamoto M DeRose R Elliott A Colombero H.-L Tan G Trail J Sullivan E Davy N Bucay L Renshaw-Gegg T.M Hughes D Hill W Pattison P Campbell S Sander G Van | 1997 | Cell1997，，2： | 6 |
| 2 | CONSORT指南:整群随机试验扩展版显示文摘 | Marion K Campbell Diana R Elbourne Douglas G Altman 杜亮 姚巡 周吉祥 | 2006 | 中国循证医学杂志2006，6，6： | 5 |
| 3 | 心肺复苏时使用喉罩通气所致的胃破裂显示文摘喉罩的应用在麻醉科气道管理上是一种根本性的变化,而且在用于复苏抢救时似乎也是如此。与面罩或支气管插管相比,它基本上既不需要太多技术也不需要培圳。。作为一种普运的设施.它在所有的医疗辅助部门和急诊科都有配备.在医院复苏抢救过程中其应用也越来越普及。使用喉罩行正压通气时,常见的并发症为漏气和胃膨胀,选二者部易被发现。下面列举一个院外心脏停搏后使用喉罩引起胃扩张、破裂及高度气腹的病例。 | Nathaniel Haslam G Claire Campbell John E Duggan James Cook 苏珊 | 2005 | 英国医学杂志中文版2005，8，2： | 3 |
| 4 | Re-challenge chemotherapy with gemcitabine plus carboplatin in patients with non-small cell lung cancer显示文摘Despite recent improvements to current therapies and the emergence of novel agents to manage advanced non-small cell lung cancer(NSCLC),the patients′overall survival remains poor.Re-challenging with first-line chemotherapy upon relapse is common in the management of small cell lung cancer but is not well reported for advanced NSCLC.NSCLC relapse has been attributed to acquired drug resistance,but the repopulation of sensitive clones may also play a role,in which case re-challenge may be appropriate.Here,we report the results of re-challenge with gemcitabine plus carboplatin in 22 patients from a single institution who had previously received gemcitabine plus platinum in the first-line setting and had either partial response or a progression-free interval of longer than 6 months.In this retrospective study,the charts of patients who underwent second-line chemotherapy for NSCLC in our cancer center between January 2005 and April 2010 were reviewed.All the patients who received a combination of gemcitabine and carboplatin for re-challenge were included in the study.These patients were offered second-line treatment on confirmation of clear radiological disease progression.The overall response rate was 15%and disease control rate was 75%.The median survival time was 10.4 months,with 46%of patients alive at 1 year.These results suggest that re-challenge chemotherapy should be considered in selected patients with radiological partial response or a progression-free survival of longer than 6 months to the initial therapy. | Khurum Khan Gerard G Hanna Lynn Campbell Paula Scullin Adnan Hussain Ruth L Eakin Jonathan McAleese | 2013 | Chinese Journal of Cancer2013，32，10： | 3 |
| 5 | Global, regional, and national causes of child mortality in 2008: a systematic analysis显示文摘 | Robert E Black Simon Cousens Hope L Johnson Joy E Lawn Igor Rudan Diego G Bassani Prabhat Jha Harry Campbell Christa Fischer Walker Richard Cibulskis Thomas Eisele Li Liu Colin Mathers | 2010 | The Lancet2010，，9730： | 3 |
| 6 | Modeling Klamath River system operations for quantity and quality 显示文摘 | Campbell S G Hanna R B Flug M | 2001 | Journal of Water Resources Planning and Management2001，127，5： | 2 |
| 7 | Global, regional, and national causes of child mortality in 2008: a systematic analysis显示文摘 | Robert E Black Simon Cousens Hope L Johnson Joy E Lawn Igor Rudan Diego G Bassani Prabhat Jha Harry Campbell Christa Fischer Walker Richard Cibulskis Thomas Eisele Li Liu Colin Mathers | 2010 | The Lancet . 2010 (9730)2010，，： | 2 |
| 8 | Anti-hypertensive drugs in children and adolescents显示文摘Worldwide the prevalence of essential hypertension inchildren and adolescents continues to increase. Tradi-tionally providers have used 'off-label' drugs to treatpediatric hypertension, meaning that rigorous clinicaltrials of these drugs have not been specifically per-formed in pediatric patient populations. Consequentlyproviders have extrapolated dosing, safety and efficacyfrom trials in adults. This practice is sub-optimal as chil-dren demonstrate unique differences in drug metabo-lism and response. Use of unstudied or understudieddrugs increases risk of adverse events and/or can leadto sub-optimal efficacy. Recognizing these concerns,regulatory agencies have created financial incentivesfor industry to conduct pediatric clinical trials. Theseincentives, coupled with the emerging pediatric hyper-tension epidemic, have spurred over 30 clinical trialsof anti-hypertensive drugs over the past 15 years andhave resulted in labeling of 10 new drugs by the UnitedStates Food and Drug Administration for treatment ofhypertension in children and adolescents. Unfortunatelythe financial incentive structures focus on newer drugsand drug classes. Consequently there is now a relativedearth of trial data for older but sometimes commonlyprescribed pediatric antihypertensive drugs. This article reviews recent pediatric antihypertensive drug trials with a focus on trial design and endpoints, drug dosing, safety, efficacy and specific drug indications. We also review the available data and experience for some of the more commonly prescribed, but less well studied 'older' pediatric antihypertensive drugs. | Patricia Y Chu Michael J Campbell Stephen G Miller Kevin D Hill | 2014 | World Journal of Cardiology2014，6，5： | 2 |
| 9 | Blind invasive diagnostic procedures in ventilatorassociated pneumonia 显示文摘 | Campbell G D | 2000 | Chest2000，117，42： | 2 |
| 10 | The chemokine receptor CCR4 in vascular recognition by cutaneous but not intestinal memory T cells 显示文摘 | Campbell J J Haraldsen G Pan J | 1999 | Nature1999，400，： | 2 |
| 11 | Sequential extraction procedure for the speciation of parficuinte trace metals显示文摘 | TESSIER A CAMPBELL P G C BLSSOM M | 1979 | Anal Chem1979，51，7： | 1 |
| 12 | Evidence that adenosine triphosphate or a related nucleotide is the transmitter substance released by non-adrenergic inhibitory nerves in the gut显示文摘 | BURNSTOCK G CAMPBELL G SATCHELL D | 1970 | Br J Pharmacol1970，40，4： | 1 |
| 13 | Receive-operating characteristic plots:a fundamental evaluation tool in clinical medicine显示文摘 | Zweig HM Campbell G | 1993 | Clin Chem1993，39，4： | 1 |
| 14 | Sequential extraction procedure for the speciation of particulate trace metals 显示文摘 | TESSIER A CAMPBELL P G C BISSON M | 1979 | Anal Chem1979，51，7： | 1 |
| 15 | Physical and chemical characteristics of wood ash 显示文摘 | Etiegnil L Campbell A G | 1991 | Bioresource Technology1991，37，2： | 1 |
| 16 | Quantitative trait loci associated with kernel traits in a soft X hard wheat cross 显示文摘 | Campbell K G Bergman C J Gualberto D G | 1999 | Crop Science1999，39，4： | 1 |
| 17 | Microbial ex- pression in soil:methods, applications and challenges 显示文摘 | Saleh L S Miller M Campbell R G | 2005 | Microbiol Methods2005，63，： | 1 |
| 18 | Transient morphological features of identified ganglion cells in living fetal and neonatal retina显示文摘 | Ramoa AS Campbell G Shatz CJ | 1987 | Science1987，237，4814： | 1 |
| 19 | Sequential extraction procedure for the sspeciation of particulate trace elements显示文摘 | Tessier A Campbell P G C | 1997 | Anal Cbem1997，51，： | 1 |
| 20 | Preliminary evi-dence that chronic confinement stress reduces the quality of gametes produced by brown and rainbow trout显示文摘 | Campbell P M Pottinger T G Sumpter J P | 1994 | Aqua-culture1994，120，15： | 1 |
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