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| 1 | mm Wave communications for 5G: implementation challenges and advances显示文摘The requirement of the fifth generation(5 G) wireless communication for high throughput motivates the wireless industry to use the mm Wave(millimeter wave) communications for its wide bandwidth advantage. To compensate the heavy path loss and increase the communications capacity, phased array beamforming and massive multiple-input multiple-output(MIMO) techniques are employed at both the user equipment(UE) and base stations(BS). Considering the commercial requirements, 5 G mm Wave large array systems should be implemented in an energy-and cost-efficient way with a small form factor. To address above issues and realize a reliable communications link, taking into account the particular characteristics of5 G mm Wave systems, this paper firstly examines the design challenges and trade-offs in system implementations, then some of the design strategies are summarized. At last, recent advance in RF front-end circuits and receiver sub-systems is then highlighted. | Lianming LI Dongming WANG Xiaokang NIU Yuan CHAI Linhui CHEN Long HE Xu WU Fuchun ZHENG Tiejun CUI Xiaohu YOU | 2018 | Science China(Information Sciences)2018，61，2： | 19 |
| 2 | Gefitinib plus Fuzheng Kang'ai Formula(扶正抗癌方) in Patients with Advanced Non-Small Cell Lung Cancer with Epidermal Growth Factor Receptor Mutation:A Randomized Controlled Trial显示文摘Objective: To evaluate the effect of Fuzheng Kang'ai Formula(扶正抗癌方, FZKA) plus gefitinib in patients with advanced non-small cell lung cancer with epidermal growth factor receptor(EGFR) mutations. Methods: A randomized controlled trial was conducted from 2009 to 2012 in South China. Seventy chemotherapynaive patients diagnosed with stage ⅢB/Ⅳ non-small cell lung cancer with EGFR mutations were randomly assigned to GF group [gefitinib(250 mg/day orally) plus FZKA(250 m L, twice per day, orally); 35 cases] or G group(gefitinib 250 mg/day orally; 35 cases) according to the random number table and received treatment until progression of the disease, or development of unacceptable toxicities. The primary endpoint [progression-free survival(PFS)] and secondary endpoints [median survival time(MST), objective response rate(ORR), disease control rate(DCR) and safety] were observed. Results: No patient was excluded after randomization. GF group had significantly longer PFS and MST compared with the G group, with median PFS of 12.5 months(95% CI 3.30–21.69) vs. 8.4 months(95% CI 6.30–10.50; log-rank P<0.01), MST of 21.5 months(95% CI 17.28–25.73) vs. 18.3 months(95% CI 17.97–18.63; log-rank P<0.01). ORR and DCR in GF group and G group were 65.7% vs. 57.1%, 94.3% vs. 80.0%, respectively(P>0.05). The most common toxic effects in the GF group and G group were rash or acne(42.8% vs. 57.1%, P>0.05), diarrhea(11.5% vs. 31.4%, P<0.05), and stomatitis(2.9% vs. 8.7%, P>0.05). Conclusion: Patients with advanced non-small cell lung cancer selected by EGFR mutations have longer PFS, MST with less toxicity treated with gefitinib plus FZKA than gefitinib alone. | YANG Xiao-bing CHAI Xiao-shu WU Wan-yin LONG Shun-qin DENG Hong PAN Zong-qi HE Wen-feng ZHOU Yu-shu LIAO Gui-ya XIAO Shu-jing | 2018 | Chinese Journal of Integrative Medicine2018，24，10： | 15 |
| 3 | Survivability-oriented optimal node density for randomly deployed wireless sensor networks显示文摘The survivability is usually critical for wireless sensor networks,which are often deployed in the unattended harsh environment.Lots of technical schemes to improve the survivability depend on the redundant resources of the sensor networks.The amount of resources is usually determined by the node density during the deployment phase.For the random deployment and random node failures,the quantitative relation between the survivability and the node density is studied.Based on the conditional survivability,the node density to meet the required survivability level is presented.Finally,the survivability for unpredictable failures and the optimal node density to maximize the price–performance ratio are also discussed. | HUANGFU Wei ZHANG ZhongShan CHAI XiaoMeng LONG KePing | 2014 | Science China(Information Sciences)2014，57，2： | 5 |
| 4 | Arsenic Trioxide Combined with Chinese Traditional Jianpiliqi Formula in the Treatment of Advanced Hepatocellular Carcinoma: An Analysis of 32 Cases显示文摘 | WU Wan-yin CHAI Xiao-shu HUANG Li LONG Shun-qin DENG Hong ZHENG Jian-xiao HE Wen-feng XUE Xiao-guang ZHANG Hai-bo | 2009 | Journal of US-China Medical Science2009，6，6： | 5 |
| 5 | Consensus on the digestive endoscopic tunnel technique显示文摘With the digestive endoscopic tunnel technique(DETT), many diseases that previously would have been treated by surgery are now endoscopically curable by establishing a submucosal tunnel between the mucosa and muscularis propria(MP). Through the tunnel, endoscopic diagnosis or treatment is performed for lesions in the mucosa, in the MP, and even outside the gastrointestinal(GI) tract.At present, the tunnel technique application range covers the following:(1)Treatment of lesions originating from the mucosal layer, e.g., endoscopic submucosal tunnel dissection for oesophageal large or circular early-stage cancer or precancerosis;(2) treatment of lesions from the MP layer, per-oral endoscopic myotomy, submucosal tunnelling endoscopic resection, etc.; and(3) diagnosis and treatment of lesions outside the GI tract, such as resection of lymph nodes and benign tumour excision in the mediastinum or abdominal cavity. With the increasing number of DETTs performed worldwide, endoscopic tunnel therapeutics, which is based on DETT, has been gradually developed and optimized. However, there is not yet an expert consensus on DETT to regulate its indications, contraindications, surgical procedure, and postoperative treatment.The International DETT Alliance signed up this consensus to standardize the procedures of DETT. In this consensus, we describe the definition, mechanism,and significance of DETT, prevention of infection and concepts of DETTassociated complications, methods to establish a submucosal tunnel, and application of DETT for lesions in the mucosa, in the MP and outside the GI tract(indications and contraindications, procedures, pre-and postoperative treatments, effectiveness, complications and treatments, and a comparison between DETT and other operations). | Ning-Li Chai Hui-Kai Li En-Qiang Linghu Zhao-Shen Li Shu-Tian Zhang Yu Bao Wei-Gang Chen Philip WY Chiu Tong Dang Wei Gong Shu-Tang Han Jian-Yu Hao Shui-Xiang He Bing Hu1 Bing Hu2 Xiao-Jun Huang Yong-Hui Huang Zhen-Dong Jin Mouen A Khashab James Lau Peng Li Rui Li De-Liang Liu Hai-Feng Liu Jun Liu Xiao-Gang Liu Zhi-Guo Liu Ying-Cai Ma Gui-Yong Peng Long Rong Wei-Hong Sha Pateek Sharma Jian-Qiu Sheng Shui-Sheng Shi Dong Wan Seo Si-Yu Sun Gui-Qi Wang Wen Wang Qi Wu Hong Xu Mei-Dong Xu Ai-Ming Yang Fang Yao Hong-Gang Yu Ping-Hong Zhou Bin Zhang Xiao-Feng Zhang Ya-Qi Zhai | 2019 | World Journal of Gastroenterology2019，25，7： | 5 |
| 6 | In situ observation of C_(60)(C(COOH)_(2))_(2) interacting with living cells using fluorescence microscopy显示文摘The interactions between nanoparticles and living cells were investigated by an imaging technique of fluorescence microscopy. For this pur- pose, the C60 derivative C60(C(COOH)2)2, a thera- peutic agent for degeneration diseases of central nervous system, was synthesized, purified and characterized. Its interaction with the living cell and penetration of the cellular membrane were in situ studied using the real time imaging technique, and its potential cytotoxicity was also examined by flow cy- tometry. The results indicate that C60(C(COOH)2)2 can easily enter cells, and is mainly located in cytoplasm by fluorescein labeling. Furthermore, C60(C(COOH)2)2 can carry the molecule that cannot cross cellular membranes into cells, because fluo- rescein compound itself cannot enter the cell or ad- here to membrane. At concentrations ranging from 1×10?2 to 1×102 mg/L, C60(C(COOH)2)2 does not show any detectable cytotoxicity. | YE Chang CHEN Chunying CHEN Zhen MENG Huan XING Li JIANG Yaxin YUAN Hui XING Gengmei ZHAO Feng ZHAO Yuliang CHAI Zhifang FANG Xiaohong HAN Dong CHEN Long WANG Chen WEI Taotao | 2006 | Chinese Science Bulletin2006，51，9： | 4 |
| 7 | Downtown Retailing Development Under Suburbanization——A Case Study of Beijing显示文摘The role of retailing has diminished in the center of cities of Western countries since its heyday in the 1920s. This trend was caused by violent transformations in the economic, social and locational contexts which involve resi- dential suburbanization, as well as new forms of commercial development out of town. As far as transforming China is concerned, the downtown retailing center has also come to turning point of development in the context of suburbaniza- tion. Based on the survey of Beijing residents’ shopping behavior, the present research tends to making clear the actual change and development problem of downtown retailing center. Combining with the macro retailing environment, re- lated influencing factors are further discussed too. Study results show that downtown retailing still plays an important part in resident’s shopping activity. However, with rapid urban sprawl, retailing in urban center has been greatly threatened by booming out-of-town commerce. In the course of such spatial change, the suburbanization of resident, the prevalence of new commercial forms and the change of consumers’ life style all have exerted their own pressure on downtown retailing. But for the special socioeconomic background of development and the support of government policy, it will still keep its vitality of retailing for a long period of time. | CHAI Yanwei SHEN Jie LONG Tao | 2007 | Chinese Geographical Science2007，17，1： | 4 |
| 8 | Ectopic expression of VRT-A2 underlies the origin of Triticum polonicum and Triticum petropavlovskyi with long outer glumes and grains显示文摘Polish wheat (Triticum polonicum) is a unique tetraploid wheat species characterized by an elongated outer glume. The genetic control of the long-glume trait by a single semi-dominant locus, P1 (from Polish wheat), was established more than 100 years ago, but the underlying causal gene and molecular nature remain elusive. Here, we report the isolation of VRT-A2, encoding an SVP-clade MADS-box transcription factor, as the P1 candidate gene. Genetic evidence suggests that in T. polonicum, a naturally occurring sequence rearrangement in the intron-1 region of VRT-A2 leads to ectopic expression of VRT-A2 in floral organs where the long-glume phenotype appears. Interestingly, we found that the intron-1 region is a key ON/OFF molecular switch for VRT-A2 expression, not only because it recruits transcriptional repressors, but also because it confers intron-mediated transcriptional enhancement. Genotypic analyses using wheat accessions indicated that the P1 locus is likely derived from a single natural mutation in tetraploid wheat, which was subsequently inherited by hexaploid T. petropavlovskyi. Taken together, our findings highlight the promoter-proximal intron variation as a molecular basis for phenotypic differentiation, and thus species formation in Triticum plants. | Jing Liu Zhaoyan Chen Zhihui Wang Zhaoheng Zhang Xiaoming Xie Zihao Wang Lingling Chai Long Song Xuejiao Cheng Man Feng Xiaobo Wang Yanhong Liu Zhaorong Hu Jiewen Xing Zhenqi Su Huiru Peng Mingming Xin Yingyin Yao Weilong Guo Qixin Sun Jie Liu Zhongfu Ni | 2021 | Molecular Plant2021，14，9： | 4 |
| 9 | Body temperature control in patients with refractory septic shock: too much may be harmful显示文摘 | YANG Yan-li LIU Da-wei WANG Xiao-ting LONG Yun ZHOU Xiang CHAI Wen-zao | 2013 | Chinese Medical Journal2013，，10： | 3 |
| 10 | Simultaneous Determination of Eight Constituents in Fruits of Rubus chingii by UPLC显示文摘Objective To develop a simple,efficient,and reliable method for routine quantitative analysis of main constituents presented in the fruits of Rubus chingii,which is widely used in Chinese materia medica(CMM),known as Fupenzi(FPZ) in Chinese.Methods An ultra performance liquid chromatography-photo diode array(UPLC-PDA) system was employed for simultaneous quantification of eight compounds,i.e.adenosine,gallic acid,brevifolin carboxylic acid,ethyl gallate,ellagic acid,kaempferol-3-O-rutinoside,kaempferol-3-O-β-D-glucopyranoside,and tiliroside.The chromatographic analysis was performed on a C_(18) column using a gradient elution of acetonitrile-0.1%formic acid aqueous solution within a runtime of 25 min.Results All calibration curves were linear(R^2> 0.9997) over the tested ranges.The intra- and inter-day precisions as determined from sample solutions were both less than 2.45%and 2.78%,respectively.The average recoveries for the eight constituents ranged from 94.77%to 101.35%with RSD ≤ 4.41%.The newly-developed method was applied to the quality assessment of various R.chingii samples,including both ripe and unripe fruits of R.chingii from different habitats.Conclusion The relative levels of the investigated compounds vary remarkably in the fruits of R.chingii collected from different habitats.As only two of the eight compounds,adenosine and ellagic acid,are determined in the ripe fruits of R.chingii,the results may explain the reason why only the unripe fruits can be used in CMM. | Xin Chai Long-fei Du Jing Yang Zhen-zuo Jiang Long Yang Yue-fei Wang Yan Zhu | 2016 | Chinese Herbal Medicines2016，8，3： | 3 |
| 11 | Chromate reduction by resting cells of Achromobacter sp. Ch-1 under aerobic conditions显示文摘 | Zemin Ma Wenjie Zhu Huaizhong Long Liyuan Chai Qingwei Wang | 2007 | Process Biochemistry2007，，6： | 2 |
| 12 | Design of 60GHz RF Transceiver in CMOS:Challenges and Recent Advances显示文摘With more than 40 years Moore scaling, the speed of CMOS transistors is around 100 GHz. Such fact makes it possible to realize mm-wave circuits in CMOS. However, with the target of achieving broadband and power-efficient operation, 60 GHz CMOS RF transceiver faces severe challenges. After reviewing the technology issues, regarding the 60 GHz applications, this paper discusses design challenges both from the system and the building block levels, and also presents some simulated or measured circuits results. | LI Lianming NIU Xiaokang CHEN Linhui CHAI Yuan ZHANG Tao SHI Jun WANG Aili LUO Ying HE Long CHENG Depeng LIU Nan CUI Tiejun YOU Xiaohu | 2014 | China Communications2014，11，6： | 2 |
| 13 | Finite element analysis of embankment failure on soft subsoil显示文摘 | CHAI J C MIURA N BERGADO D T LONG P V | 1997 | Geotechnical Engineering1997，28，2： | 1 |
| 14 | The rs2227481 C>T Polymorphism in the IL22 Gene Promoter Significantly Reduces the Risk of Liver,Lung,and Gastric Cancer in a Han Chinese Population显示文摘Cancer is a serious threat to public health and the economy worldwide.Statistical data from the World Health Organization(WHO)in 2018 have demonstrated that lung cancer is the most commonly diagnosed cancer(11.6%of the total cases)and the leading cause of cancer death(18.4%of the total cancer deaths),closely followed bygastric cancer(5.7%and 8.2%),and liver cancer(4.7%and 8.2%). | CHAI Long Long XIAO Ying Xuan MENG Ling Han WANG Huan FENG Xian Hong GU Xiu Li LI Qi Chang XIONG Qian Tao CHEN Bi Feng | 2021 | Biomedical and Environmental Sciences2021，34，7： | 1 |
| 15 | Simple method of modeling PVD - improved subsoil 显示文摘 | Chai Jin - chun Shen Shui - long | 2001 | Journal of Geotechnical and Geoenvironmental Engineering2001，127，11： | 1 |
| 16 | Solvent extraction of zinc from zinc sulfate solution显示文摘 | Long H Z Chai L Y Qin W Q | 2010 | Journal of Central South University of Technology (English Edition)2010，17，4： | 1 |
| 17 | Towards a bright future:The versatile applications of organic solar cells显示文摘Due to the mechanical flexibility,light weight,aesthetics,absorption tunability and environmental friendliness,organic solar cells(OSCs)have superior application potential over their inorganic counterparts including silicon and perovskite solar cells(PSCs).Thanks to these benefits,the past decade have witnessed the rapid growth of flexible OSCs,semitransparent OSCs and indoor OSCs.In this progress report,we firstly overview the recent advance of the applications of the three promising OSCs.Subsequently,we sketch the critical points for the three classes of OSCs and highlight the efforts paid by the research community to address these issues.Besides,we discuss some popular strategies to afford great performance of each kind of OSC,respectively,and underline the corresponding breakthrough directions.Last but not least,we present the remaining challenges for advancing the commercial applications of these three classes of OSCs. | Junjiang Wu Mengyuan Gao Yubo Chai Pengke Liu Bo Zhang Junwei Liu Long Ye | 2021 | Materials Reports(Energy)2021，1，4： | 1 |
| 18 | Contribution of hydrogenperoxide to the cytotoxicity of green tea and red wines显示文摘 | Chai P C Long L H Halliwell B | 2003 | Biochem Biophys Res Commun2003，304，： | 1 |
| 19 | Galena-pyrolusite co- extraction in sodium chloride solution and its electrochemical analysis 显示文摘 | Long H Z Chai L Y Qin W Q | 2010 | Translations of Nonferrous Metals Society of China2010，20，5： | 1 |
| 20 | Green-revertible Chlorina 1 (grcl) is required for the biosynthesis of chlorophyll and the early development of chloroplasts in rice 显示文摘 | Li J Wang Y Chai J Wang L Wang C Long W Wang D Wang Y Zheng M Peng C | 2013 | Journal of Plant Biology2013，56，5： | 1 |
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