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| 1 | Expression of human cytomegalovirus components in the brain tissues of patients with Rasmussen's encephalitis显示文摘Rasmussen's encephalitis(RE) is a rare and severe progressive epileptic syndrome with unknown etiology. Infection by viruses, including human cytomegalovirus(HCMV), has been speculated to be a potential trigger for RE. However, no viral antigens have been detected in the brains of patients with RE; thus, a possible clinical linkage between viral infections and RE has not been firmly established. In this study, we evaluated the expression of HCMV pp65 antigen in brain sections from 26 patients with RE and 20 non-RE patients by immunohistochemistry and in situ hybridization, and assessed the associations between HCMV infection and clinical parameters.Elevated expression of HCMV pp65 protein and DNA was observed in 88.5%(23/26) and 69.2%(18/26) of RE cases, respectively. In the non-RE group, HCMV pp65 antigen was detected only in two cases(10%), both of which were negative for DNA staining. Additionally, the intensity of HCMV pp65 staining was correlated with a shorter duration of the prodromal stage, younger age of seizure onset, and more severe unilateral cortical atrophy. Elevated expression of HCMV pp65 was observed in RE brain tissue and was correlated with the clinical features of RE disease. In summary, our results suggested that HCMV infection may be involved in the occurrence and progression of RE disease. Thus, further studies are needed to determine whether early treatment with anti-HCMV antibodies could modulate the course of RE. | Yao Zhang Yisong Wang Sichang Chen Shuai Chen Yuguang Guan Changqing Liu Tianfu Li Guoming Luan Jing An | 2017 | Virologica Sinica2017，32，2： | 9 |
| 2 | Multistring analysis of wellhead movement and uncemented casing strength in offshore oil and gas wells显示文摘This paper presents a theoretical method and a finite element method to describe wellhead movement and uncemented casing strength in offshore oil and gas wells. Parameters considered in the theoretical method include operating load during drilling and completion and the temperature field, pressure field and the end effect of pressure during gas production. The finite element method for multistring analysis is developed to simulate random contact between casings. The relevant finite element analysis scheme is also presented according to the actual procedures of drilling, completion and gas production. Finally, field cases are presented and analyzed using the proposed methods. These are four offshore wells in the South China Sea. The calculated wellhead growths during gas production are compared with measured values. The results show that the wellhead subsides during drilling and completion and grows up during gas production. The theoretical and finite element solutions for wellhead growth are in good agreement with measured values and the deviations of calculation are within 10%. The maximum von Mises stress on the uncemented intermediate casing occurs during the running of the oil tube. The maximum von Mises stress on the uncemented production casing, calculated with the theoretical method occurs at removing the blow-out-preventer(BOP) while that calculated with the finite element method occurs at gas production. Finite element solutions for von Mises stress are recommended and the uncemented casings of four wells satisfy strength requirements. | Liu Xiuquan Chen Guoming Chang Yuanjiang Zhang Lei Zhang Weiguo Xie Hua | 2014 | Petroleum Science2014，11，1： | 7 |
| 3 | Direct Reduction of Solid Fe_2O_3 in Molten CaCl_2 by Potentially Green Process显示文摘Sintered (300°C) porous pellets of Fe2O3 were electrolyzed to Fe in molten CaCl2 (800–900°C) under argon at 1.8–3.2 V for 2–20 h. The laboratory scale experiments show that it was a potentially direct green method to produce Fe powder. At lower electrolysis voltage (<2.2 V), higher current efficiency (>90%) and smaller energy consumption (~3.0 kWh/kg) can be obtained. When the electrolysis voltage was above 2.4 V, the deposition of metal Ca from the salt lowered the current efficiency and increased the energy consumption. The electrolysis voltage also had effects on the micrographs of the reduced powder. The cubic particles can be seen in the products at the voltage lower than 2.2 V; when the voltage was higher than 2.2 V, it was nodular. The reduction proceeds at the cathode in two steps, i.e., from Fe2O3 to FeO and then to Fe. The oxygen emits at the anode. The process is potentially free of carbon emission and produces two useful products at both cathode and anode, promising a zero-emission technology for the extractive metallurgical industry. | Guoming Li Dihua Wang Zhen Chen | 2009 | Journal of Materials Science & Technology2009，25，6： | 5 |
| 4 | Detection of EBV and HHV6 in the Brain Tissue of Patients with Rasmussen's Encephalitis显示文摘Rasmussen's encephalitis (RE) is a rare pediatric neurological disorder, and the exact etiology is not clear. Viral infection may be involved in the pathogenesis of RE, but conflicting results have reported. In this study, we evaluated the expression of both Epstein-Barr virus (EBV) and human herpes virus (HHV) 6 antigens in brain sections from 30 patients with RE and16 control individuals by immunohistochemistry. In the RE group, EBV and HHV6 antigens were detected in 56.7% (17/30) and 50% (15/30) of individuals, respectively. In contrast, no detectable EBV and HHV6 antigen expression was found in brain tissues of the control group. The co-expression of EBV and HHV6 was detected in 20.0% (6/30) of individuals. In particular, a 4-year-old boy had a typical clinical course, including a medical history of viral encephalitis,intractable epilepsy, and hemispheric atrophy. The co-expression of EBV and HHV6 was detected in neurons and astrocytes in the brain tissue, accompanied by a high frequency of CD8?T cells. Our results suggest that EBV and HHV6 infection and the activation of CD8?T cells are involved in the pathogenesis of RE. | Dong Liu Xin Wang Yisong Wang Peigang Wang Dongying Fan Sichang Chen Yuguang Guan Tianfu Li Jing An Guoming Luan | 2018 | Virologica Sinica2018，33，5： | 4 |
| 5 | γδT17 Cells Promote the Accumulation and Expansion of Myeloid-Derived Suppressor Cells in Human Colorectal Cancer显示文摘 | Pin Wu Dang Wu Chao Ni Jun Ye Wuzhen Chen Guoming Hu Zhen Wang Changrong Wang Zhigang Zhang Wenjie Xia Zhigang Chen Ke Wang Tao Zhang Jinghong Xu Yuehua Han Ting Zhang Xianguo Wu Jianwei Wang Weihua Gong Shu Zheng Fuming Qiu Jun Yan Jian Huang | 2014 | Immunity2014，，5： | 2 |
| 6 | Feasibility of C_(3)F_(7)CN/CO_(2)gas mixtures in high-voltage DC GIL:a review on recent advances显示文摘With the rise of renewable energy resources,especially offshore wind power plant,the DC transmission concept has attracted more and more attention.The selection of eco-friendly insulating gas,as most critical insulating part of gas-insulated equipment is top priority for developing highly reliable system.Moreover,it is acknowledged that eco-friendly C_(3)F_(7)CN/CO_(2) gas mixtures have become a potential alternative to SF_(6) gas due to its excellent performance.This study reviews the basic physical properties of C_(3)F_(7)CN gas/gas mixtures and insulation properties including the gas gap breakdown and surface flashover performance at DC,as well as lightning impulse voltage.Investigation about the gas stability is presented,including the compatibility of gas with solid materials in gas-insulated transmission line(GIL),and the decomposition characteristics under long-term electrical and thermal stresses.The important progress on the charge accumulation characteristics of gas-solid interface in the novel gas environment under DC voltage stress is analysed.Finally,the key issues that need to be paid attention to and further followed through regarding the application of this novel gas in GIL are summarised and put forward.This study hopefully can provide a complete reference for the development of eco-friendly DC gas insulation equipment with C_(3)F_(7)CN/CO_(2) gas mixtures. | Youping Tu Geng Chen Cong Wang Yuming Shao Yujing Tong Chuanyang Li Guoming Ma Tohid Shahsavarian | 2020 | High Voltage2020，5，4： | 2 |
| 7 | Capacitive Imaging Technique for the Inspection of Composite Sucker Rod显示文摘Composite sucker rod has been extensively used due to its high strength, light weight and corrosion resistive nature. However, such composite sucker rod is diffcult for conventional non-destructive evaluation(NDE) techniques to inspect because of its complex material and/or structure. It is thus useful to embark research on developing novel NDE technique to comply the inspection requirement. This work demonstrates the feasibility of using the capacitive imaging(CI) technique for the inspection of composite sucker rod. Finite element(FE) models were constructed in COMSOL to simulate the detection of defects in the glass-fiber layer and on the carbon core surface. An FE Model based inversion method is proposed to obtain the profile of the carbon core. Preliminary CI experimental results are then presented, including the detection of surface wearing defect in the glass-fiber layer, and obtaining the profile of the carbon core. A set of accelerated aging experiments were also carried out and the results indicate that the CI technique is potentially useful in evaluating the ageing status of such composite sucker rod. The CI technique described in this work shows great potential to target some challenging tasks faced in the non-destructive evaluation of composite sucker rod, including quality control, defect detection and ageing assessment. | Kefan Wang Xiaokang Yin Chen Li Wei Li Guoming Chen | 2019 | Chinese Journal of Mechanical Engineering2019，32，6： | 2 |
| 8 | Structural optimization of 2-D array probe for ACFM显示文摘 | CHEN Guoming LI Wei WANG Zexin | 2007 | NDT&E International2007，40，6： | 1 |
| 9 | Nonlinear dynamic analysis of deepwater drilling risers subjected to random loads显示文摘 | Chang Yuanjiang Chen Guoming Sun Youyi | 2008 | China Ocean Engineering2008，22，3： | 1 |
| 10 | Simulation and assessment of SOitoxic environment after ignition of uncontrolled sour gas flowof well blowout in hills显示文摘 | Zhu Yuan Chen Guoming | 2010 | Journal of Hazardous Materials2010，178，13： | 1 |
| 11 | Preparation and antimicrobial activity of rosin- based carbamate group- containing quaternary ammonium salt derivatives 显示文摘 | Liu Guifeng Chen Caifeng Wu Guoming | 2013 | Bioresources2013，8，3： | 1 |
| 12 | Structural optimazation of 2-D array probe for alternaing current field measurement显示文摘 | Chen Guoming Li Wei Wang Zexin | 2007 | NDT&E International2007，40，6： | 1 |
| 13 | Detecting surface features on conducting specimens through an insulation layer using a capacitive imaging technique显示文摘 | Yin Xiaokang David A Hutchins Chen Guoming | 2012 | NDT E Int2012，，： | 1 |
| 14 | Quantitative risk analysisof toxic gas release caused poisoning: a CFD and dose-response model combined approach显示文摘 | ZHANG Bo CHEN Guoming | 2010 | Process Safetyand Environmental Protection2010，88，4： | 1 |
| 15 | Environment-friendly Insulating Gases for HVDC Gas-insulated Transmission Lines显示文摘Environment-friendly gas insulating mediums adapted to a DC gas-insulated transmission line(GIL)electric field condition is the key to the next generation of Environment-friendly HVDC GILs.In this paper,we review the literature on sulfur hexafluoride(SF6)alternatives including the scientific understanding,control,and implementation of gas-solid systems in this type of power transmission.First,the structure-activity relationship between the molecular structure and physico-chemical properties of Environment-friendly insulating gases is presented.Then,the search and prediction of important physicochemical properties of gases are summarized.Subsequently,in view of the potential of environmental friendly insulating gases,the swarm parameters of gas discharge and breakdown properties in a quasi-uniform field,inhomogeneous field,and at the gas-solid interface,that need to be taken into account with industrialized DC GILs are discussed.The latest research progress on insulation characteristics,especially the polarity effect in DC gas-solid insulation systems,the sensitivity to the electrode surface state,and the non-uniformity of the electric field,and the influence of metal particles and their variation with air pressure,is highlighted.In addition,the heat transfer characteristics of insulating gases,related to DC GIL transmission with a large current-carrying capacity and the influence of alternative gases on the heat transfer characteristics are described.Finally,aiming at solving the contradiction of low environmental impact,high dielectric strength and low liquefaction temperatures in the selection of alternative gases,an coordinated regulation model for Environment-friendly gases in DC GILs is established.Considerations for future work on this topic are also presented. | Geng Chen Youping Tu Cong Wang Jue Wang Zhikang Yuan Guoming Ma Jian Wang Bo Qi Chuanyang Li | 2021 | CSEE Journal of Power and Energy Systems2021，7，3： | 1 |
| 16 | Relationships of the dimensions of intercultural communication competence 显示文摘 | Chen Guoming | 1989 | Communication Quarterly1989，，37： | 1 |
| 17 | Synthesis and properties of copolymer microemulsions of siloxane and acrylate with a high solid content显示文摘 | Zhang Li Zhang Chen Li Guoming | 2007 | J Appl Polym Sci2007，104，2： | 1 |
| 18 | Structural optimization of 2-D array probe for alternating current field measurement显示文摘 | CHEN Guoming LI Wei WANG Zexin | 2007 | NDT&E International2007，40，6： | 1 |
| 19 | Measuring In-tercultural Sensitivity in Different Cultural Context显示文摘 | Fritz&-Mollenberg&Chen Guoming | 2002 | Intercultural Communication Studies2002，，11： | 1 |
| 20 | Intercultural Communication Competence: Some Perspectives of Research 显示文摘 | Chen Guoming | 1990 | Eastern Communication Association1990，，： | 1 |
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