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| 1 | Cropland redistribution to marginal lands undermines environmental sustainability显示文摘Cropland redistribution to marginal land has been reported worldwide;however,the resulting impacts on environmental sustainability have not been investigated sufficiently.Here we investigated the environmental impacts of cropland redistribution in China.As a result of urbanization-induced loss of high-quality croplands in south China(~8.5 t ha^(-1)),croplands expanded to marginal lands in northeast(~4.5 t ha^(-1)) and northwest China(~2.9 t ha^(-1)) during 1990-2015 to pursue food security.However,the reclamation in these low-yield and ecologically vulnerable zones considerably undermined local environmental sustainability,for example increasing wind erosion(+3.47%),irrigation water consumption(+34.42%),fertilizer use(+20.02%) and decreasing natural habitats(-3.11%).Forecasts show that further reclamation in marginal lands per current policies would exacerbate environmental costs by 2050.The future cropland security risk will be remarkably intensified because of the conflict between food production and environmental sustainability.Our research suggests that globally emerging reclamation of marginal lands should be restricted and crop yield boost should be encouraged for both food security and environmental benefits. | Wenhui Kuang Jiyuan Liu Hanqin Tian Hao Shi Jinwei Dong Changqing Song Xiaoyong Li Guoming Du Yali Hou Dengsheng Lu Wenfeng Chi Tao Pan Shuwen Zhang Rafiq Hamdi Zherui Yin Huimin Yan Changzhen Yan Shixin Wu Rendong Li Jiuchun Yang Yinyin Dou Wenbin Wu Liqiao Liang Bao Xiang Shiqi Yang | 2022 | National Science Review2022，9，1： | 13 |
| 2 | Circular BANP knockdown inhibits the malignant progression of residual hepatocellular carcinoma after insufficient radiofrequency ablation显示文摘Background:Circular RNAs(circRNAs)are endogenous non-coding RNAs,some of which have pathological roles.The current study aimed to explore the role of circRNA BTG3-associated nuclear protein(circ-BANP)binding with let-7f-5p and its regulation of the toll-like receptor 4(TLR4)/signal transducer and activator of transcription 3(STAT3)signaling pathway in residual hepatocellular carcinoma(HCC)after insufficient radiofrequency ablation(RFA).Methods:Circ-BANP,let-7f-5p,and TLR4 expressions in HCC samples were assessed using reverse transcription-quantitative polymerase chain reaction(RT-qPCR)and Western blotting.Bioinformatics prediction,RNA pull-down assay,and dual luciferase reporter gene assay were used to analyze the relationships among circ-BANP,let-7f-5p,and TLR4.Huh7 cells were used to generate an in vitro model of residual HCC,defined as Huh7-H cells,which were transfected with either a plasmid or the sequence of circ-BANP,let-7f-5p,or TLR4.Expression of circ-BANP,let-7f-5p,and TLR4 mRNA was determined by RT-qPCR.TLR4,STAT3,p-STAT3,vascular endothelial growth factor A,vascular endothelial growth factor receptor-2,and epithelialmesenchymal transformation(EMT)-related factors proteins were determined by Western blotting.Cell proliferation was determined by cell counting kit-8 and 5-Ethynyl-2’-deoxyuridine(EdU)assay and cell migration and invasion by Transwell assay.Animal studies were performed by inducing xenograft tumors in nude mice.Results:Circ-BANP and TLR4 mRNAs were upregulated in HCC tissues(the fold change for circ-BANP was 1.958 and that for TLR4 was 1.736 relative to para-tumors)and expression further increased following insufficient RFA(fold change for circBANP was 2.407 and that of TLR4 was 2.224 relative to para-tumors).Expression of let-7f-5p showed an opposite tendency(fold change for let-7f-5p in HCC tissues was 0.491 and that in tumors after insufficient RFA was 0.300 relative to paratumors).Competitive binding of circ-BANP to let-7f-5p was demonstrated and TLR4 was identified as a target of let-7f-5p(P<0.01).Knockdown of circ-BANP or elevation of let-7f-5p expression inhibited the TLR4/STAT3 signaling pathway,proliferation,invasion,migration,angiogenesis,and EMT in Huh7 and Huh7-H cells(P<0.01).The effects induced by circBANP knockdown were reversed by let-7f-5p inhibition.Overexpression of TLR4 reversed the impact of let-7f-5p upregulation on the cells(P<0.01).Silencing of circ-BANP inhibited the in vivo growth of residual HCC cells after insufficient RFA(P<0.01).Conclusions:Knockdown of circ-BANP upregulated let-7f-5p to inhibit proliferation,migration,and EMT formation in residual HCC remaining after insufficient RFA.Effects occur via regulation of the TLR4/STAT3 signaling pathway. | Guoming Li Jian Kong Shuying Dong Haigang Niu Shilun Wu Wenbing Sun | 2022 | Chinese Medical Journal2022，，13： | 2 |
| 3 | γδT17 Cells Promote the Accumulation and Expansion of Myeloid-Derived Suppressor Cells in Human Colorectal Cancer显示文摘 | Pin Wu Dang Wu Chao Ni Jun Ye Wuzhen Chen Guoming Hu Zhen Wang Changrong Wang Zhigang Zhang Wenjie Xia Zhigang Chen Ke Wang Tao Zhang Jinghong Xu Yuehua Han Ting Zhang Xianguo Wu Jianwei Wang Weihua Gong Shu Zheng Fuming Qiu Jun Yan Jian Huang | 2014 | Immunity2014，，5： | 2 |
| 4 | ASYMPTOTIC SURROGATE CONSTRAINT METHOD AND ITS CONVERGENCE FOR A CLASS OF SEMI-INFINITE PROGRAMMING显示文摘A class of constrained semi\|infinite minimax problem is transformed into a simple constrained problem, by means of discretization decomposition and maximum entropy method, making use of surrogate constraint. The paper deals with the convergence of this asymptotic approach method. | Wan Zhongping\ Wu Guoming | 1999 | Applied Mathematics(A Journal of Chinese Universities)1999，14，4： | 2 |
| 5 | Review of flash sintering with strong electric field显示文摘Flash sintering is a novel field‐assisted sintering technology for ceramics that allows a dramatic reduction in processing time and temperature.Since 2010,when flash sintering was first reported,it has been a focus of research interest in the field of materials science.Recent study results have confirmed that the sintering temperature decreases with the strength of the applied electric field;for some ceramics,the sintering temperature can be lowered even to room temperature.This represents an innovative breakthrough for ceramic sintering at ultra‐low temperatures.However,once the electric field strength in flash sintering is increased,new questions and challenges arise,such as whether or not partial discharge occurs in the green body if under electro‐thermal coupling stress,how to quantitatively analyse the impact of discharge on sintering,and,moreover,whether the sintering mechanism under a strong electric field is consistent with that under a weak electric field.These research questions require knowledge of partial discharge detection,dielectric theory,and other topics that are beyond the scope of materials science.To address this need,this review summarises the work carried out in flash sintering with a strong electric field from the perspective of high voltage and insulation technology.First,the flash sintering process and mechanism are briefly introduced.Then,the published literature on flash sintering with a strong electric field for various ceramic materials is summarised in depth.In addition,experimental phenomena that are observed in flash sintering with a strong electric field,such as flash and blackening,are discussed.Finally,some suggestions for future work are presented.It is anticipated that the knowledge gap between different areas of study can be filled by this review. | Hongyang Zhou Xiang Li Yuchen Zhu Jieming Liu Angxuan Wu Guoming Ma Xilin Wang Zhidong Jia Liming Wang | 2022 | High Voltage2022，7，1： | 2 |
| 6 | High‐performance ZnO varistor ceramics prepared by arc‐induced flash sintering with low energy consumption at room temperature显示文摘The development of ultra‐high voltage transmission lines requires a ZnO arrester with excellent electrical response and high voltage gradient.Compared with conventional preparation methods,flash sintering allows fast production of novel high‐performance ZnO varistor ceramics with low energy consumption and controlled grain growth.Herein,ZnO varistor ceramics were prepared using the flash sintering method at an air pressure of 21 kPa for 60 s at 25℃.The results showed that the flash‐sintered samples had fine grains and reduced loss of volatile elements.Moreover,the voltage gradient,leakage current density,and non‐linear coefficient of the flash‐sintered varistor ceramics were significantly improved compared with those of conventionally sintered samples.Owing to the short preparation time and absence of a heating process,the energy consumption of the proposed flash sintering method was significantly reduced to 10%of that by conventional sintering.The proposed method is a promising approach for the preparation of ZnO arresters with excellent electrical properties and serves as an effective method that realises energy saving and emission reduction. | Angxuan Wu Zhixiang Zhu Xilin Wang Nianping Yan Hongyang Zhou Rongxia Huang Guoming Ma Zhidong Jia Liming Wang | 2022 | High Voltage2022，7，2： | 2 |
| 7 | Engineering immune-responsive biomaterials for skin regeneration显示文摘The progress of biomaterials and tissue engineering has led to significant advances in wound healing,but the clinical therapy to regenerate perfect skin remains a great challenge.The implantation of biomaterial scaffolds to heal wounds inevitably leads to a host immune response.Many recent studies revealed that the immune system plays a significant role in both the healing process and the outcome.Immunomodulation or immuno-engineering has thus become a promising approach to develop pro-regenerative scaffolds for perfect skin regeneration.In this paper,we will review recent advancements in immunomodulating biomaterials in the field of skin repair and regeneration,and discuss strategies to modulate the immune response by tailoring the chemical,physical and biological properties of the biomaterials.Understanding the important role of immune responses and manipulating the inherent properties of biomaterials to regulate the immune reaction are approaches to overcome the current bottleneck of skin repair and regeneration. | Pingli Wu Yangyang Liang Guoming Sun | 2021 | Biomaterials Translational2021，2，1： | 1 |
| 8 | Preparation and antimicrobial activity of rosin- based carbamate group- containing quaternary ammonium salt derivatives 显示文摘 | Liu Guifeng Chen Caifeng Wu Guoming | 2013 | Bioresources2013，8，3： | 1 |
| 9 | Promoter methylation profiles between human lung adencarcinoma MDR A549/DDP ceils with its progenitor A549 cells显示文摘 | Ruffing Guo Guoming Wu Haidong Li | 2013 | Biol Pharm Bull2013，36，8： | 1 |
| 10 | FeOOH-loaded mesoporous silica nanoparticles as a theranostic platform with pH-responsive MRI contrast enhancement and drug release显示文摘The development of stimuli-responsive theranostic platforms is of great demand for efficient cancer treatment because they can enhance diagnostic specificity and sensitivity.In this work,we report a p H-responsive theranostic nanoplatform based on Fe OOH clusters loaded mesoporous silica nanoparticles(Fe@MSNs).The as-synthesized Fe@MSNs possess activatable T_1magnetic resonance imaging(MRI)performance that can respond to the acidic microenvironment of solid tumor to turn on T_1singals by releasing paramagnetic Fe^(3+)ions.The Fe@MSNs are biocompatible without appreciable cytotoxicity.Moreover,the unique mesoporous structure endows the Fe@MSNs with significant advantages to effectively deliver chemotherapeutic drug for inhibiting the growth of solid tumor.We believe that this novel p H-responsive theranostic nanoplatform holds great promise in cancer treatment. | Guoming Huang Rui Liu Yuehua Hu Shi-Hua Li Ying Wu Yuan Qiu Jingying Li Huang-Hao Yang | 2018 | Science China Chemistry2018，61，7： | 1 |
| 11 | Study on the manufacture of rayon fiber from a PF/DMSO solvent system显示文摘 | Yang Zhili Wu Guoming Mei Qianfang | 1987 | Cellulose Chem Technol1987，21，： | 1 |
| 12 | Ex vivo expanded human circulating Vδ1 γδT cells exhibit favorable therapeutic potential for colon cancer显示文摘 | Dang Wu Pin Wu Xianguo Wu Jun Ye Zhen Wang Shuai Zhao Chao Ni Guoming Hu Jinghong Xu Yuehua Han Ting Zhang Fuming Qiu Jun Yan Jian Huang | 2015 | OncoImmunology2015，，3： | 1 |
| 13 | Application of hot spring gases to the study of active volcanoes in the Changbaishan Mountain region, Northeast China显示文摘The authors reviewed the history of geochemistry involved in active volcano monitoring and analyzed the relationship between variations in volcanic gas composition observed at the Changbaishan Volcano Observatory and volcanic activities. It is concluded that both geochemical method and routine gas analysis can provide the information about volcanic activity and earthquake activity, and both of them can play an important role in predicting volcano eruption. | WU Chengzhi LIU Guoming WANG Pan | 2009 | Chinese Journal Of Geochemistry2009，28，4： | 1 |
| 14 | Electron-ion collider in China显示文摘Lepton scattering is an established ideal tool for studying inner structure of small particles such as nucleons as well as nuclei.As a future high energy nuclear physics project,an Electron-ion collider in China(EicC)has been proposed.It will be constructed based on an upgraded heavy-ion accelerator,High Intensity heavy-ion Accelerator Facility(HIAF)which is currently under construction,together with a new electron ring.The proposed collider will provide highly polarized electrons(with a po-larization of 80%)and protons(with a polarization of 70%)with variable center of mass energies from 15 to 20 GeV and the luminosity of(2–3)×1033 cm^(−2)·s^(−1).Polarized deuterons and Helium-3,as well as unpolarized ion beams from Carbon to Uranium,will be also available at the EicC.The main foci of the EicC will be precision measurements of the structure of the nucleon in the sea quark region,including 3D tomography of nucleon;the partonic structure of nuclei and the parton interaction with the nuclear environment;the exotic states,especially those with heavy flavor quark contents.In addition,issues fundamental to understanding the origin of mass could be addressed by measurements of heavy quarkonia near-threshold production at the EicC.In order to achieve the above-mentioned physics goals,a hermetical detector system will be constructed with cutting-edge technologies.This document is the result of collective contributions and valuable inputs from experts across the globe.The EicC physics program complements the ongoing scientific programs at the Jefferson Laboratory and the future EIC project in the United States.The success of this project will also advance both nuclear and particle physics as well as accelerator and detector technology in China. | Daniele PAnderle Valerio Bertone Xu Cao Lei Chang Ningbo Chang Gu Chen Xurong Chen Zhuojun Chen Zhufang Cui Lingyun Dai Weitian Deng Minghui Ding Xu Feng Chang Gong Longcheng Gui Feng-Kun Guo Chengdong Han Jun He Tie-Jiun Hou Hongxia Huang Yin Huang KrešImir KumeričKi LPKaptari Demin Li Hengne Li Minxiang Li Xueqian Li Yutie Liang Zuotang Liang Chen Liu Chuan Liu Guoming Liu Jie Liu Liuming Liu Xiang Liu Tianbo Liu Xiaofeng Luo Zhun Lyu Boqiang Ma Fu Ma Jianping Ma Yugang Ma Lijun Mao Cédric Mezrag HervéMoutarde Jialun Ping Sixue Qin Hang Ren Craig DRoberts Juan Rojo Guodong Shen Chao Shi Qintao Song Hao Sun PawełSznajder Enke Wang Fan Wang Qian Wang Rong Wang Ruiru Wang Taofeng Wang Wei Wang Xiaoyu Wang Xiaoyun Wang Jiajun Wu Xinggang Wu Lei Xia Bowen Xiao Guoqing Xiao Ju-Jun Xie Yaping Xie Hongxi Xing Hushan Xu Nu Xu Shusheng Xu Mengshi Yan Wenbiao Yan Wencheng Yan Xinhu Yan Jiancheng Yang Yi-Bo Yang Zhi Yang Deliang Yao Zhihong Ye Peilin Yin C-PYuan Wenlong Zhan Jianhui Zhang Jinlong Zhang Pengming Zhang Yifei Zhang Chao-Hsi Chang Zhenyu Zhang Hongwei Zhao Kuang-Ta Chao Qiang Zhao Yuxiang Zhao Zhengguo Zhao Liang Zheng Jian Zhou Xiang Zhou Xiaorong Zhou Bingsong Zou Liping Zou | 2021 | Frontiers of physics2021，16，6： | 1 |
| 15 | The numerical study of piston ring elastohydrodynamic lubrication by the multigrid method显示文摘 | GUOMING WU ZHAOXIONG CHEN | | 0，，： | 1 |
| 16 | Consensus on pediatric epilepsy Che up surgery for young children:an investigation by the China Association Against Epilepsy task force on epilepsy surgery显示文摘Researchers have widely acknowledged the therapeutic value of epilepsy surgery for drug-resistant epilepsy.None-theless,there is a substantial gap in the surgical treatment for appropriate candidates owing to several factors,particularly in the population of young children.To standardize the protocols of preoperative evaluation and sur-gery of young children for epilepsy surgery,the China Association Against Epilepsy has appointed an expert task force to standardize the protocols of preoperative evaluation and surgery in pediatric epilepsy patients.It adopted the modifed Delphi method and performed two rounds of surveys through an anonymous inquiry among 75 experts from four subgroups including pediatric neurologists,epileptologists,pediatric epilepsy surgeons,and functional neurosurgeons.The survey contents contained:(1)the participants,comprising children aged≤6 years;(2)adopted DRE definition proposed by the International League Against Epilepsy in 2010;and(3)investigated epilepsy surgery,principally referring to curative epilepsy surgeries.The neuromodulation therapies were excluded because of the differences in treatment mechanisms from the above-mentioned surgeries.According to the Delphi process,a con-sensus was achieved for most aspects by incorporating two rounds of surveys including preoperative assessment,sur-gical strategies and techniques,and perioperative and long-term postoperative management,despite controversial opinions on certain items.We hope the results of this consensus will improve the level of surgical treatment and man-agement of intractable epilepsy in young children. | Lixin Cai Kai Zhang Wenjing Zhou Xiaoqiu Shao Yuguang Guan Tao Yu Ye Wu Shuhua Chen Rui Zhao Shuli Liang Xun Wu Guoming Luan Yuwu Jiang Jianguo Zhang Xiaoyan Liu | 2023 | Acta Epileptologica2023，6，3： | 1 |
| 17 | Computation and measurement of winding tension in ring spinning显示文摘 | Ye Guoming Wu Wen-ying Chen Rui-qi | 1998 | Journal of China Textile University1998，15，4： | 1 |
| 18 | Transmission Probability Method for Soving Neutron Transport Equation in Three-Dimensional Triangular-z Geometry 显示文摘 | Liu Guoming Wu Hongchun Cao Liangzhi | 2008 | Nucl Eng Dis2008，238，9： | 1 |
| 19 | Correlation between per-well average dynamic reserves and initial absolute open flow potential(AOFP) for large gas fields in China and its application显示文摘Based on performance data of over 600 wells in 32 large gas fields of different types in China, the correlation is established between per-well average dynamic reserves( G) and average initial absolute open flow potential(IAOFq) of each field, and its connotation and applicability are further discussed through theoretical deduction. In log-log plot, G vs. IAOFq exhibit highly dependent linear trend, which implicates the compatibility between G and IAOFq attained through development optimization to reach the balance among annual flow capacity, maximum profits and certain production plateau, that is to match productivity with rate maintenance capacity. The correlation can be used as analogue in new gas field development planning to evaluate the minimum dynamic reserves which meet the requirement of stable and profitable production, and facilitate well pattern arrangement. It can also serve as criteria to appraise the effectiveness and infill drilling potential of well patterns for developed gas fields. | LI Xizhe LIU Xiaohua SU Yunhe WU Guoming LIU Huaxun LU Linlin WAN Yujin GUO Zhenhua SHI Shi | 2018 | Petroleum Exploration and Development2018，45，6： | 0 |
| 20 | A sustained release of BMP2 in urine-derived stemcells enhances the osteogenic differentiation and the potential of bone regeneration显示文摘Cell-based tissue engineering is one of the optimistic approaches to replace current treatments for bone defects.Urine-derived stem cells(USCs)are obtained non-invasively and become one of the promising seed cells for bone regeneration.An injectable BMP2-releasing chitosan microspheres/type I collagen hydrogel(BMP2-CSM/Col I hydrogel)was fabricated.USCs proliferated in a time-dependent fashion,spread with good extension and interconnected with each other in different hydrogels both for 2D and 3D models.BMP2 was released in a sustained mode for more than 28 days.Sustained-released BMP2 increased the ALP activities and mineral depositions of USCs in 2D culture,and enhanced the expression of osteogenic genes and proteins in 3D culture.In vivo,the mixture of USCs and BMP2-CSM/Col I hydrogels effectively enhanced bone regeneration,and the ratio of new bone volume to total bone volume was 38%after 8weeks of implantation.Our results suggested that BMP2-CSM/Col I hydrogels promoted osteogenic differentiation of USCs in 2D and 3D culture in vitro and USCs provided a promising cell source for bone tissue engineering in vivo.As such,USCs-seeded hydrogel scaffolds are regarded as an alternative approach in the repair of bone defects. | Shuang Wu Zhao Chen Xi Yu Xin Duan Jialei Chen Guoming Liu Min Gong Fei Xing Jiachen Sun Shishu Huang Zhou Xiang | 2022 | Regenerative Biomaterials2022，9，1： | 0 |
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