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| 1 | Methylation of DAPK and THBS1 genes in esophageal gastric-type columnar metaplasia显示文摘AIM: To explore methylation of DAPK, THBS1, CDH-1, and p14 genes, and Helicobacter pylori(H. pylori) status in individuals harboring esophageal columnar metaplasia.METHODS: Distal esophageal mucosal samples obtained by endoscopy and histologically diagnosed as gastric-type(non-specialized) columnar metaplasia, were studied thoroughly. DNA was extracted from paraffin blocks, and methylation status of deathassociated protein kinase(DAPK), thrombospondin-1(THBS1), cadherin-1(CDH1), and p14 genes, was examined using a methyl-sensitive polymerase chain reaction(MS-PCR) and sodium bisulfite modification protocol. H. pylori cag A status was determined by PCR.RESULTS: In total, 68 subjects(33 females and 35 males), with a mean age of 52 years, were included. H. pylori cag A positive was present in the esophageal gastric-type metaplastic mucosa of 18 individuals. DAPK, THSB1, CDH1, and p14 gene promoters were methylated by MS-PCR in 40(58.8%), 33(48.5%), 46(67.6%), and 23(33.8%) cases of the 68 esophageal samples. H. pyloristatus was associated with methylation of DAPK(P = 0.003) and THBS1(P = 0.019).CONCLUSION: DNA methylation occurs in cases of gastric-type(non-specialized) columnar metaplasia of the esophagus, and this modification is associated with H. pylori cag A positive infection. | Roberto Herrera-Goepfert Luis F Onate-Ocana José Luis Mosqueda-Vargas Luis A Herrera Clementina Castro Julia Mendoza Rodrigo González-Barrios | 2016 | World Journal of Gastroenterology2016，22，18： | 3 |
| 2 | Assessment and impact of diastolic function by echocardiography in elderly patients显示文摘Doppler echocardiography 是为对心脏舒张的机能障碍的评价的标准答案,它逐渐地作为心失败的一个原因被认出,在特别老。用 Doppler echocardiography 技术的联合,识别心脏舒张的机能障碍的等级是可能的,估计左室的充满压力并且建立心脏舒张的机能障碍的慢性。这些导出 physiologically 的措施广泛地对左心压力的侵略大小被验证了并且被显示了在大量临床的背景预示地珍贵。这评论探索机制,并且来临到对心脏舒张的机能障碍的评价在老。为临床医生的挑战是从与正常变老联系的那些识别 pathophysiological 变化。当在联合,和花的很长时间使用了进报道时, Doppler echocardiographic 参数在对在更老的病人的 dyspnoea 的评价是有用的并且提供预示的卓见。 | Clementina Dugo Marzia Rigolli Andrea Rossi Gillian A Whalley | 2016 | Journal of Geriatric Cardiology2016，13，3： | 3 |
| 3 | Ultrasonographic and hysteroscopic outcomes of uterine scar healing after cesarean section: Comparison of two types of single‐layer suture显示文摘 | Oronzo Ceci Clementina Cantatore Marco Scioscia Claudia Nardelli Mini Ravi Antonella Vimercati Stefano Bettocchi | 2012 | Journal of Obstetrics and Gynaecology Research2012，，11： | 1 |
| 4 | Foetal outcome in gestational diabetes in south Indians 显示文摘 | Ramachandran A Snehalatha C Clementina M | 1998 | Diabetes Res Clin Pract1998，41，3： | 1 |
| 5 | Fermentative production of superoxide dismutase with Kluyveromyces marxianus显示文摘 | Clementina D Alberto A Simona Z | 2007 | J Ind Microbiol Biotechnol2007，34，1： | 1 |
| 6 | The frail person and his caregiver:cure,care or simultaneous care:A conceptual article显示文摘 | Michele Vitacca Clementina Isimbaldi Angelo Mainini | 2011 | J Med Pers2011，9，1： | 1 |
| 7 | Redefining professionalism: Romanian secondary educa- tion teachers and the private tutoring system 显示文摘 | Popa Simona and Clementina Acedo | 2006 | International Journal of Educational Development2006，26，1： | 1 |
| 8 | Microbial translocation is associated with residual viral replication in HAART-treated HIV+ subjects with <50copies/ml HIV-1 RNA显示文摘 | Silvia Baroncelli Clementina Maria Galluzzo Maria Franca Pirillo Maria Grazia Mancini Liliana Elena Weimer Mauro Andreotti Roberta Amici Stefano Vella Marina Giuliano Lucia Palmisano | 2009 | Journal of Clinical Virology2009，，： | 1 |
| 9 | Prognostic factors for ampullary adenocarcinomas: tumor stage, tumor histology, tumor location, immunohistochemistry and microsatellite instability显示文摘 | Fausto Sessa Daniela Furlan Clementina Zampatti Ileana Carnevali Francesca Franzi Carlo Capella | 2007 | Virchows Archiv2007，，3： | 1 |
| 10 | Hereditary hemochromatosis type 1 phenotype modifiers in Italian patients. The controversial role of variants in HAMP , BMP2 , FTL and SLC40A1 genes显示文摘 | Francesca Clementina Radio Silvia Majore Caterina Aurizi Fiammetta Sorge Gianfranco Biolcati Sara Bernabini Irene Giotti Francesca Torricelli Diana Giannarelli Carmelilia De Bernardo Paola Grammatico | 2015 | Blood Cells, Molecules and Diseases2015，，1： | 1 |
| 11 | Antioxidant effect of red wine polyphenols on red blood cells显示文摘 | Idolo Tedesco Maria Russo Paola Russo Giuseppe Iacomino Gian Luigi Russo Antonio Carraturo Clementina Faruolo Luigi Moio Rosanna Palumbo | 2000 | The Journal of Nutritional Biochemistry2000，，2： | 1 |
| 12 | Combination of carbamazepine and Valproate in different dose proportions in maximal electroshock seizure model in mice显示文摘 | Sun Meizhen Clementina Mvan Rijn Lui Yuxi | 2002 | Epilepsy Research2002，51，： | 1 |
| 13 | Prostaglandin E2 inhibits the interleukin-2 promoter activity through down-regulation of the Oct-dependent transcription of the octamer motif显示文摘 | Maria F Clementina M Anonietta RF | 1996 | Cell Immunol1996，172，3： | 1 |
| 14 | Effect of linear alkylbenzene sulfonates on the growth of aerobic heterotrophic cultivable bacteria isolated from an agricultural soil显示文摘 | María del Mar Sánchez-Peinado Jesús González-López Belén Rodelas Vanesa Galera Clementina Pozo María Victoria Martínez-Toledo | 2008 | Ecotoxicology2008，，6： | 1 |
| 15 | Formulation to optimize the risk reductionprocess based on LOPA显示文摘 | Clementina Ramirez-Marengo Julio de Lira-Flores AntiocoL6pez-Molina | 2013 | Journal of Loss Prevention in Process Industries2013，26，3： | 1 |
| 16 | Sorafenib plus octreotide is an effective and safe treatment in advanced hepatocellular carcinoma: multicenter phase II So.LAR. study显示文摘 | Salvatore Del Prete Liliana Montella Michele Caraglia Luigi Maiorino Gregorio Cennamo Vincenzo Montesarchio Guido Piai Antonio Febbraro Luciano Tarantino Elena Capasso Giovannella Palmieri Rosario Guarrasi Maddalena Bianco Rosanna Mamone Clementina Savast | 2010 | Cancer Chemotherapy and Pharmacology2010，，5： | 1 |
| 17 | Denitrifying activity of Xanthobacter autotrophicus strains isolated from a submerged fixed-film reactor显示文摘 | Miguel Angel Gómez Belén Rodelas Florentina Sáez Clementina Pozo María Victoria Martínez-Toledo Ernesto Hontoria Jesús González-López | 2005 | Applied Microbiology and Biotechnology2005，，5： | 1 |
| 18 | Onset of inflammatory bowel diseases during combined α-interferon and ribavirin therapy for chronic hepatitis C: report of two cases显示文摘 | Federica Villa Maria Grazia Rumi Clementina Signorelli Simone Saibeni Ersilio Del Ninno Stefano Ferrero Bogetto Roberto de Franchis Maurizio Vecchi | 2005 | European Journal of Gastroenterology & Hepatology2005，，11： | 1 |
| 19 | Gender and Age-Dependent Etiology of Community-Acquired Urinary Tract Infections显示文摘 | Enrico Magliano Vittorio Grazioli Loredana Deflorio Antonia Isabella Leuci Roberto Mattina Paolo Romano Clementina Elvezia Cocuzza A. I. El Sakka R. Gonzalez | 2012 | The Scientific World Journal2012，，： | 1 |
| 20 | Analysis of Epoxyeicosatrienoic Acids by Chiral Liquid Chromatography/Electron Capture Atmospheric Pressure Chemical Ionization Mass Spectrometry Using[13C]-Analog Internal Standards显示文摘 | CLEMENTINA M SEON H L BLAIR A | | 0，，： | 1 |
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