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| 1 | 血液透析滤过的技术及应用现状显示文摘血液透析滤过逐渐成为一种常见的肾脏替代治疗方式。血液透析滤过在一次透析中,溶质的清除方式同时包含了弥散和对流,可以同时实现小分子和中大分子量毒素的有效清除。来自中国和国际的近期报告显示,使用在线透析滤过治疗的患者总数逐渐增加。从目前的研究和临床应用情况,亚太地区的临床经验和实践模式与欧洲有所不同,需要根据实际情况进行具体分析。本文综述了血液透析滤过的技术要求和临床研究及应用的现状。 | 陈育青 Bernard Canaud | 2021 | 中国血液净化2021，20，10： | 4 |
| 2 | Irradiation uniformity at the Laser MegaJoule facility in the context of the shock ignition scheme显示文摘The use of the Laser MegaJoule facility within the shock ignition scheme has been considered. In the first part of the study, one-dimensional hydrodynamic calculations were performed for an inertial confinement fusion capsule in the context of the shock ignition scheme providing the energy gain and an estimation of the increase of the peak power due to the reduction of the photon penetration expected during the high-intensity spike pulse. In the second part, we considered a Laser MegaJoule configuration consisting of 176 laser beams that have been grouped providing two different irradiation schemes. In this configuration the maximum available energy and power are 1.3 MJ and 440 TW. Optimization of the laser–capsule parameters that minimize the irradiation non-uniformity during the first few ns of the foot pulse has been performed. The calculations take into account the specific elliptical laser intensity profile provided at the Laser MegaJoule and the expected beam uncertainties. A significant improvement of the illumination uniformity provided by the polar direct drive technique has been demonstrated. Three-dimensional hydrodynamic calculations have been performed in order to analyse the magnitude of the azimuthal component of the irradiation that is neglected in twodimensional hydrodynamic simulations. | Mauro Temporal Benoit Canaud Warren J. Garbett Rafael Ramis Stefan Weber | 2014 | High Power Laser Science and Engineering2014，2，2： | 3 |
| 3 | Hidden risks associated with conventional short intermittent hemodialysis:A call for action to mitigate cardiovascular risk and morbidity显示文摘The development of maintenance hemodialysis(HD)for end stage kidney disease patients is a success story that continues to save many lives.Nevertheless,intermittent renal replacement therapy is also a source of recurrent stress for patients.Conventional thrice weekly short HD is an imperfect treatment that only partially corrects uremic abnormalities,increases cardiovascular risk,and exacerbates disease burden.Altering cycles of fluid loading associated with cardiac stretching(interdialytic phase)and then fluid unloading(intradialytic phase)likely contribute to cardiac and vascular damage.This unphysiologic treatment profile combined with cyclic disturbances including osmotic and electrolytic shifts may contribute to morbidity in dialysis patients and augment the health burdenof treatment. As such, HD patients are exposed to multiple stressors including cardiocirculatory,inflammatory, biologic, hypoxemic, and nutritional. This cascade of events can be termed thedialysis stress storm and sickness syndrome. Mitigating cardiovascular risk and morbidityassociated with conventional intermittent HD appears to be a priority for improving patientexperience and reducing disease burden. In this in-depth review, we summarize the hidden effectsof intermittent HD therapy, and call for action to improve delivered HD and develop treatmentschedules that are better tolerated and associated with fewer adverse effects. | Bernard Canaud Jeroen P Kooman Nicholas M Selby Maarten Taal Andreas Maierhofer Pascal Kopperschmidt Susan Francis Allan Collins Peter Kotanko | 2022 | World Journal of Nephrology2022，11，2： | 2 |
| 4 | Why hemodialysis patients are in a prooxidant state? What could be done to correct the pro/antioxidant imbalance 显示文摘 | Morena M Cristol JP Canaud B | 2000 | Blood Purif2000，18，3： | 1 |
| 5 | The importance of diabetic nephropathy in current nephrological practice 显示文摘 | Locatelli F Canaud B Eckardt KU | 2003 | Nephrol Dial Transplant2003，18，9： | 1 |
| 6 | Mortality risk for patients receiving hemodiafiltration versus hemodialysis: Euro- pean results from the DOPPS 显示文摘 | Canaud B Bragg - Gresham JL Marshall MR | 2006 | Kidney Int2006，69，11： | 1 |
| 7 | Urea as a marker of adequacy in hemodialysis : Lesson from in vivo urea dynamics monitoring显示文摘 | Canaud B Bosc JY Cabrol L | 2000 | Kidney Int2000，58，： | 1 |
| 8 | Effect of online hemodiafiltration on morbidity and mortality of chronic kidney disease patients显示文摘 | Canaud B | 2007 | Contrib Nephrol2007，158，： | 1 |
| 9 | Dialysis adequacy today: a Euro pean perspective显示文摘 | Locatelli F Canaud B | 2012 | Nephrol Dial Transplant2012，27，30： | 1 |
| 10 | Haemodialysis with online monitoring equipment: tools or toys 显示文摘 | Locatelli F Buoncristiani U Canaud B | 2005 | Nephrol Dial Transplant2005，20，1： | 1 |
| 11 | Low initial aspect-ratio direct-drive target designs for shock- or self-ignition in the context of the laser Megajoule显示文摘 | V. Brandon B. Canaud M. Temporal R. Ramis | 2014 | Nuclear Fusion2014，，8： | 1 |
| 12 | Creatine kinitie modeling:a simple and reliable tool for the assessment of protein nutritional status in hemodialysis patients显示文摘 | Canaud B Garred IJ Argiles A | 1995 | Nephrol-Dial-Transplant1995，10，： | 1 |
| 13 | The importanceof diabetic nephropathy in current nephrological practice显示文摘 | Locatelli F Canaud B Eckardt K U | 2003 | Nephrol Dia Transplant2003，18，9： | 1 |
| 14 | Polar direct drive illumination uniformity provided by the Orion facility显示文摘 | Mauro Temporal Benoit Canaud Warren J. Garbett Franck Philippe Rafael Ramis | 2013 | The European Physical Journal D2013，，10： | 1 |
| 15 | Recommendations of iron management in chronic kid- ney patients 显示文摘 | Canaud B | 2006 | Nephrol Ther2006，11，2： | 1 |
| 16 | Slow continuous and daily ultrafitration for refractory congestive heart failure显示文摘 | Canaud B Leblanc M Leray-Maragues H | 1998 | Nephrol Dial Transplant1998，13，4： | 1 |
| 17 | High-fluxor low-flux dialysis: a position statement following publication ofthe Mem- brane Permeability Outcome study 显示文摘 | TattersaU J Canaud B Heimburger O | 2010 | Nephrol Dial Trans2010，25，4： | 1 |
| 18 | Optimal management of central venous catheters for hemodialysis 显示文摘 | Canaud B Chenine L Henriet D | 2008 | Contrib Nephrol2008，161，： | 1 |
| 19 | Hemodiafiltration : clini-cal evidence and remaining questions 显示文摘 | Blankestijn PJ Ledebo I Canaud B | 2010 | Kidney Internation-al2010，77，7： | 1 |
| 20 | 2D analysis of direct-drive shock-ignited HiPER-like target implosions with the full laser megajoule显示文摘 | B. Canaud S. Laffite V. Brandon M. Temporal | 2012 | Laser and Particle Beams2012，，2： | 1 |
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