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| 1 | Precise localization of small pulmonary nodules using Pre-VATS with Xper-CT in combination with real-time fluoroscopy-guided coil:report of 15 patients显示文摘Purpose: This study aimed to evaluate the value of precise localization of nodules using pre-video-assisted thoracic surgery(VATS) Xper–CT in combination with real-time fluoroscopy-guided coil in the resection of pulmonary nodules using VATS. Materials and Methods: Precise localization of nodules using Xper-CT in combination with real-time fluoroscopy-guided coil and wedge resection using VATS were conducted on 15 patients with 17 small pulmonary nodules(diameter 0.5–1.5 cm) from April 2015 to January 2016. The value of localization was evaluated in terms of procedure time, type of coils, associated complications of localization, and VATS success rate. Results: The success rate of coil localization was found to be 100% in the primary stage(as shown by the CT scan), and the average procedure time was 30–45 min(35.6 ± 3.05 min). No deaths or major complications occurred. Minor complications included five incidents of pneumothorax(the morbidity was 29.4%, 5/17; no patient required chest tube drainage). The dislocation of coil was found in one patient. The results of pathological examination of 17 small pulmonary nodules revealed 11 primary lung cancers, 1 mesenchymal tumor, 3 nonspecific chronic inflammations, 1 hamartoma, and 1 tuberculosis. Two patients with primary lung cancer underwent lobectomy with mediastinal lymph node dissection. Conclusion: The preoperative precise localization of small pulmonary nodules using Xper-CT-guided coil is an effective and safe technique. It helps in the resection of nodules using VATS. It increases the rate of lung wedge resection with few complications and allows for proper diagnosis with a low thoracotomy conversion rate. | Jiemin Cheng Changyu Li Liangwen Wang Jiting Liang Zhiping Yan Jiani Hu Huibing Shi | 2018 | Journal of Interventional Medicine2018，1，2： | 8 |
| 2 | Thermodynamic analysis of metal dusting on iron in CO-H_2-H_2O atmosphere显示文摘This paper provides a calculation method for carbon activity in CO-H2-H2O atmosphere. The thermodynamic parameters (aC)gas (carbon activity in environment) of different compositions at any temperature can be obtained by △GTo . A theoretical analysis has been conducted into the thermodynamic role of iron and the dependence of possible metal-dusting occurrence on temperature, gas composition and total pressure. In CO-H2-H2O gas mixtures, decreasing the molar fraction of H2O and increasing total pressure expands the temperature region for metal dusting. In CO-H2-H2O gas mixture of different compositions at any temperature and pressure for Fe, depending on relative values of (aC)gas, (aC)Fe3C/Fe and aC = 1, three zones were found to exist. | Na Lei Changyu Zhou Guiming Hu Cheng Chen | 2009 | Journal of Natural Gas Chemistry2009，18，2： | 1 |
| 3 | A QSAR of the toxicity of amino-benzenes and their structures显示文摘 | Lu Xu Yaping Wu Changyu Hu Hua Li | 2000 | Science in China Series B: Chemistry2000，，2： | 1 |
| 4 | Fuzzy comprehensive evaluation method on flood-control risk consequence assessment of bridge 显示文摘 | Wang Hongwei Hu Changyu Yu Jianxing | 2012 | Affective Computing and Intelligent Interaction2012，137，3： | 1 |
| 5 | A practical method for solving the ignition delay of small solid rocket motor显示文摘 | ZHANG Qiufang HU Changyu LI Yuesen | 2003 | Theory and Pratice of Energetic Materials2003，5，： | 1 |
| 6 | Wavelength stability in a hybrid photonic crystal laser through controlled nonlinear absorptive heating in the reflector显示文摘The need for miniaturized,fully integrated semiconductor lasers has stimulated significant research efforts into realizing unconventional configurations that can meet the performance requirements of a large spectrum of applications,ranging from communication systems to sensing.We demonstrate a hybrid,silicon photonicscompatible photonic crystal(PhC)laser architecture that can be used to implement cost-effective,high-capacity light sources,with high side-mode suppression ratio and milliwatt output output powers.The emitted wavelength is set and controlled by a silicon PhC cavity-based reflective filter with the gain provided by a Ⅲ–Ⅴ-based reflective semiconductor optical amplifier(RSOA).The high power density in the laser cavity results in a significant enhancement of the nonlinear absorption in silicon in the high Q-factor PhC resonator.The heat generated in this manner creates a tuning effect in the wavelength-selective element,which can be used to offset external temperature fluctuations without the use of active cooling.Our approach is fully compatible with existing fabrication and integration technologies,providing a practical route to integrated lasing in wavelength-sensitive schemes. | Andrei P.Bakoz Alexandros A.Liles Alfredo A.Gonzalez-Fernandez Tatiana Habruseva Changyu Hu Evgeny A.Viktorov Stephen P.Hegarty Liam O’Faolain | 2018 | Light(Science & Applications)2018，7，1： | 1 |
| 7 | Gynecologic infections seen in ThinPrep cytological test in Wuhan, China显示文摘这研究试图分析流行细菌,在 ThinPrep cytological 测试(TCT ) 的 Candida, Trichomonas,和人的乳头状瘤病毒(HPV ) 感染表现在中国武汉的女人上。ThinPrep 油迹被二个独立富有经验的病理学家屏蔽并且从 2008 ~ 2010 报导了。46 866 ThinPrep 油迹的一个总数被学习,并且有发炎的油迹被分析。44 162 个注册病人,发炎变化被观察在 21 935 (49.7%) 并且在 6884 的特定的感染(31.4%) 。检测的感染如下:细菌, 5663 (82.3%) ;Candida, 825 (12.0%) ;Trichomonas, 273 (4.0%) ;并且 HPV, 148 (2.1%) 。重要变化在在 2010 前后经历了 TCT 的女人之中在细菌和 Candida 的流行被发现。< 啜 class= “ a-plus-plus ” > 2 揭示了在 2010 以后在油迹发现的特定的感染的一个增加的比例(P = 0.000 ) 。在结论,细菌的感染在 ThinPrep 油迹是最可检测的,由 Candida 和 Trichomonas 列在后面。TCT 识别的感染的流行被发现在在中国的以前的文学类似。 | Hang Zhou Yao Jia Jian Shen Shaoshuai Wang Xiong Li Ru Yang Kecheng Huang Ting Hu Fangxu Tang Jin Zhou Jingping Yuan Lei Huang Xun Tian Zhilan Chen Qinghua Zhang Changyu Wang Ling Xi Dongrui Deng Hui Wang Ding Ma Shuang Li | 2014 | Frontiers of Medicine2014，8，2： | 1 |
| 8 | 阿卡波糖心血管评估(ACE)试验依据与设计显示文摘心血管疾病(CVD)患者和糖耐量减低(IGT)者患2型糖尿病(T2DM)的风险较高。生活方式的调整或药物干预可以延缓T2DM的进展,但没有证据表明它们能够降低该人群的心血管风险。阿卡波糖是一种α-葡萄糖苷酶抑制剂,能够降低餐后血糖;其被证明能够使T2DM风险降低25%,并有可能降低无CVD的IGT受试者的心血管风险。阿卡波糖心血管评估(ACE)试验是一项随机、安慰剂对照、双盲、二级预防试验,受试者为7500例患有冠心病(定义为既往心肌梗死、不稳定型心绞痛或当前稳定的心绞痛)并伴有IGT且年龄I〉50岁的患者。以1:1的比例将患者随机分组,分别在标准CVD治疗药物基础上服用阿卡波糖50mg,每天3次或相匹配的安慰剂。排除标准包括糖尿病病史、过去3个月内发生过心血管事件、NYHAⅢ/Ⅳ级心力衰竭、重度肝病和重度肾功能损害。本研究在中国内地和中国香港的约150家医院内进行。主要复合心血管终点是至首次发生心血管死亡、非致死性心肌梗塞或非致死性卒中的时间。次要终点包括全因死亡和新发T2DM。ACE是一项对CVD进行二级预防的研究,用于评估冠心病患者和IGT者在标准心血管治疗的基础上加用阿卡波糖的效果。CVD的治疗与干预标准包括合理使用能降低心血管风险因素的药物,例如B肾上腺素能受体阻断剂、血管紧张素转换酶抑制剂、抗血小板药物和降血脂药物。在高血糖症患者中,血糖可能是另一个可调节的风险因素。流行病学证据表明,IGT会导致CVD发病率和死亡率上升,尽管其程度低于T2DM患者。餐后高血糖是餐后血糖代谢障碍的一个指标,它是心血管事件的一个独立的预测因子,因为负荷后血糖值与心血管事件的相关性比空腹血糖值更强,即使在非糖尿病受试者中也是这样。餐后代谢障碍影响动脉粥样硬化与CVD的机制包含多种因素。体内血糖的急性上升会诱导内皮功能障碍,可能是通过氧化应激引起。急性高血糖症也与血栓形成的激活以及炎性级联反应相关。用药物治疗来降低餐后高血糖会导致CVD的替代指标下降。在之前未用药物而被随机分配接受瑞格列奈(一种短效促泌剂,主要对餐后高血糖进行控制)或格列本脲(一种长效磺脲类药物)的患者中,使用瑞格列奈的患者C反应蛋白和白细胞介素-6的下降程度较大,颈动脉内一中膜厚度指标也是如此。阿卡波糖能够通过延缓碳水化合物的消化和吸收,降低餐后高血糖,改善内皮功能障碍,降低炎性指标(包括细胞核因子.xB活化及其核转位以及C反应蛋白),减少凝血因子(纤维蛋白原和凝血素),减少低密度脂蛋白氧化,降低颈动脉内一中膜厚度。相比那格列奈,阿卡波糖餐后血流量介导的血管扩张改善更显著。它也会放大二肽基肽酶4抑制剂阿格列汀的降血糖效应。IGT者中进行的降糖药物临床试验大都集中在预防T2DM上,而对心血管结局鲜有关注。STOP.NIDDM试验(1429名IGT受试者被随机分配阿卡波糖或安慰剂)显示,在平均3.3年的随访期后,阿卡波糖降低T2DM风险25%。后续分析也显示心肌梗死风险以及预先指定的任一心血管事件风险下降,但只有47名受试者发生了CVD。一项关于阿卡波糖的荟萃分析提示,阿卡波糖能显著降低T2DM患者的心肌梗死风险和心血管死亡、卒中、外周动脉疾病、心绞痛、心力衰竭和血管重建的风险。这些数据支持了该假设:使用阿卡波糖降低餐后高血糖能够消除IGT者的高CVD风险。目前为止唯一的有关降低餐后血糖药物的前瞻性CVD结局试验NAVIGATOR显示,那格列奈对心血管结局没有影响。ORIGIN试验(增大基础胰岛素用量以降低IGT者或早期T2DM患者的空腹血糖值)结果也显示对心血管结局没有影响。ACE试验的目的是确定阿卡波糖是否能够减少冠心病患者和IGT者中的心血管事件,其次要结局是T2DM的预防情况。 | Rury R Holman Mary A Bethel Juliana CN Chan Jean-Louis Chiasson Zoe Doran Junbo Ge Hertzel Gerstein Yong Huo John J McMurray Lars Ryden Winitha Liyanage Stefan Schroder Michal Tendera Michael J Theodorakis Jaakko Tuomilehto Wenying Yang Dayi Hu Changyu Pan 潘长玉 | 2016 | 国际内分泌代谢杂志2016，36，3： | 1 |
| 9 | A Practical method for solving the ignition delay of small solid rocketmotor显示文摘 | ZHANG Qiufang HU Changyu LI yuesen | 2003 | Theory and Practice of Energetic Materials2003，5，： | 1 |
| 10 | Advancing the pressure sensing performance of conductive CNT/PDMS composite film by constructing a hierarchical-structured surface显示文摘Flexible pressure sensors have attracted wide attention due to their applications to electronic skin,health monitoring,and human-machine interaction.However,the tradeoff between their high sensitivity and wide response range remains a challenge.Inspired by human skin,we select commercial silicon carbide sandpaper as a template to fabricate carbon nanotube(CNT)/polydimethylsiloxane(PDMS)composite film with a hierarchical structured surface(h-CNT/PDMS)through solution blending and blade coating and then assemble the h-CNT/PDMS composite film with interdigitated electrodes and polyurethane(PU)scotch tape to obtain an h-CNT/PDMS-based flexible pressure sensor.Based on in-situ optical images and finite element analysis,the significant compressive contact effect between the hierarchical structured surface of h-CNT/PDMS and the interdigitated electrode leads to enhanced pressure sensitivity and a wider response range(0.1661 kPa^(-1),0.4574 kPa^(-1)and 0.0989 kPa^(-1)in the pressure range of 0–18 kPa,18–133 kPa and 133–300 kPa)compared with planar CNT/PDMS composite film(0.0066 kPa^(-1)in the pressure range of 0–240 kPa).The prepared pressure sensor displays rapid response/recovery time,excellent stability,durability,and stable response to different loading modes(bending and torsion).In addition,our pressure sensor can be utilized to accurately monitor and discriminate various stimuli ranging from human motions to pressure magnitude and spatial distribution.This study supplies important guidance for the fabrication of flexible pressure sensors with superior sensing performance in next-generation wearable electronic devices. | Ye Zhao Taoyu Shen Minyue Zhang Rui Yin Yanjun Zheng Hu Liu Hongling Sun Chuntai Liu Changyu Shen | 2023 | Nano Materials Science2023，5，4： | 1 |
| 11 | A Novel Airplane Detection Algorithm Based on Deep CNN显示文摘 | Ying Wang Aili Wang Changyu Hu | 2018 | 国际计算机前沿大会会议论文集2018，，1： | 0 |
| 12 | Adjuvant chemotherapy versus adjuvant concurrent chemoradiotherapy after radical surgery for early-stage cervical cancer:a randomized,non-inferiority,multicenter trial显示文摘We conducted a prospective study to assess the non-inferiority of adjuvant chemotherapy alone versus adjuvant concurrent chemoradiotherapy (CCRT) as an alternative strategy for patients with early-stage (FIGO 2009 stage IB–IIA) cervical cancer having risk factors after surgery. The condition was assessed in terms of prognosis, adverse effects, and quality of life. This randomized trial involved nine centers across China. Eligible patients were randomized to receive adjuvant chemotherapy or CCRT after surgery. The primary end-point was progression-free survival (PFS). From December 2012 to December 2014, 337 patients were subjected to randomization. Final analysis included 329 patients, including 165 in the adjuvant chemotherapy group and 164 in the adjuvant CCRT group. The median follow-up was 72.1 months. The three-year PFS rates were both 91.9%, and the five-year OS was 90.6% versus 90.0% in adjuvant chemotherapy and CCRT groups, respectively. No significant differences were observed in the PFS or OS between groups. The adjusted HR for PFS was 0.854 (95% confidence interval 0.415–1.757;P = 0.667) favoring adjuvant chemotherapy, excluding the predefined non-inferiority boundary of 1.9. The chemotherapy group showed a tendency toward good quality of life. In comparison with post-operative adjuvant CCRT, adjuvant chemotherapy treatment showed non-inferior efficacy in patients with early-stage cervical cancer having pathological risk factors. Adjuvant chemotherapy alone is a favorable alternative post-operative treatment. | Danhui Weng Huihua Xiong Changkun Zhu Xiaoyun Wan Yaxia Chen Xinyu Wang Youzhong Zhang Jie Jiang Xi Zhang Qinglei Gao Gang Chen Hui Xing Changyu Wang Kezhen Li Yaheng Chen Yuyan Mao Dongxiao Hu Zimin Pan Qingqin Chen Baoxia Cui Kun Song Cunjian Yi Guangcai Peng Xiaobing Han Ruifang An Liangsheng Fan Wei Wang Tingchuan Xiong Yile Chen Zhenzi Tang Lin Li Xingsheng Yang Xiaodong Cheng Weiguo Lu Hui Wang Beihua Kong Xing Xie Ding Ma | 2023 | Frontiers of Medicine2023，17，1： | 0 |
| 13 | Deep learning of DEM image texture for landform classification in the Shandong area,China显示文摘Landforms are an important element of natural geographical environment,and textures are the research basis for the spatial differentiation,evolution features,and analysis rules of the landform.Using the regional difference of texture to describe the spatial distribution pattern of macro landform features is helpful to the landform classification and identification.Digital elevation model(DEM)image texture,which gives full expression to texture difference,is key data source to reflect the surface features and landform classification.Following the texture analysis,landform features analysis is assistant to different landforms classification,even in landform boundary.With the increasing accuracy requirement of landform information acquisition in geomorphic thematic mapping,hierarchical landform classification has become the focus and difficulty in research.Recently,the pattern recognition represented by Convolutional Neural Network has made great achievements in landform research,whose multichannel feature fusion structure satisfies the network structure of different landform classification.In this paper,DEM image texture was taken as the data source,and gray level co-occurrence matrix was applied to extract texture measures.Owing to the similarity of similar landform and the difference of different landform in a certain scale,a comprehensive texture factor reflecting landform features was proposed,and the spatial distribution pattern of landform features was systematically analyzed.On this basis,the coupling relationship between texture and landform type was explored.Thus,the deep learning method of Convolutional Neural Network is used to train the texture features,and the second-class landform classification is carried out through softmax.The classification results in small relief and mid-relief low mountains,overall accuracy are 84.35%and 69.95%respectively,while kappa coefficient are 0.72 and 0.40 respectively,were compared to that of traditional unsupervised landform classification results,and the superiority of Convolutional Neural Network classification was verified,it approximately improved 6%in overall accuracy and 0.4 in kappa coefficient. | Yuexue XU Hongchun ZHU Changyu HU Haiying LIU Yu CHENG | 2022 | Frontiers of Earth Science2022，16，2： | 0 |
| 14 | Engineering hierarchical heterostructure material based on metal-organic frameworks and cotton fiber for high-efficient microwave absorber显示文摘Rational construction of hierarchical multi-component materials with abundant heterostructure is evolving as a promising strategy to achieve excellent metal-organic frameworks(MOFs)based electromagnetic wave(EMW)absorbers.Herein,hierarchical heterostructure WS_(2)/CoS_(2)@carbonized cotton fiber(CCF)was fabricated using the ZIF-67 MOFs nanosheets anchored cotton fiber(ZIF-67@CF)as a precursor through the tungsten etching,sulfurization,and carbonization process.Apart from the synergetic effect of dielectric-magnetic dual-loss mechanism,the hierarchical heterostructure and multicomponent of WS_(2)/CoS_(2)@CCF also display improved impedance matching.Furthermore,numerous W-S-Co bands and heterojunction interfaces of heterogeneous WS_(2)/CoS_(2)are beneficial to promoting additional interfacial/dipole polarization loss and conductive loss,thereby enhancing the EMW attenuation performance.Based on the percolation theory,a good balance between impedance matching and EMW absorption capacity was achieved for the WS_(2)/CoS_(2)@CCF/paraffin composite with 20 wt.%filler loading,exhibiting strong EMW absorption capability with a minimum reflection loss(RLmin)value of−51.26 dB at 17.36 GHz with 2 mm thickness and a maximum effective absorption bandwidth(EABmax)as wide as 6.72 GHz.Our research will provide new guidance for designing high-efficient MOFs derived EMW absorbers. | Yan Guo Hu Liu Dedong Wang Zeinhom M.El-Bahy Jalal T.Althakafy Hala M.Abo-Dief Zhanhu Guo Ben Bin Xu Chuntai Liu Changyu Shen | 2022 | Nano Research2022，15，8： | 0 |
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