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| 1 | Ultrasonography guided percutaneous radiofrequency ablation for hepatic cavernous hemangioma显示文摘AIM: Hepatic cavernous hemangioma (HCH) is the mostcommon benign tumor of the liver and its management isstill controversial. Recent successin situ radiofrequencyablation of hepatic malignancies has led us to consider usingthis technique in patients with HCH. This study was to assessthe efficacy, safety, and complications of percutaneousradiofrequency ablation (PRFA) under ultrasonographyguidance in patients with HCH.METHODS: Twelve patients (four men and eight women,age ranged 33-56 years, mean age was 41.7 years) with 15hepatic cavernous hemangiomas (2.5 cm to 9.5 cm) weretreated using the RF-2000 generator and 10-needle LeVeenelectrode percutaneously guided by B-ultrasound. Lesionslarger than 3 cm were treated by multiple overlappingablations that encompass the entire lesion as well as a rimof normal liver tissue (approximately 0.5 cm).RESULTS: All the patients who received PRFA therapy hadno severe pain, bleeding or bile leakage during and afterthe procedures. Nine to 34 months′ follow-up (mean, 21months) by ultrasound and/or spiral CT scan demonstratedthat the ablated lesions in this group were shrunk remarkably,and the shrunken range was 38-79 % (mean, 67 % per 21months). The contrast enhancement was disappeared withinthe tumor or at its periphery in all cases on spiral CT scansobtained 3 to 6 months after treatment.CONCLUSION: The results of this study suggest that PRFAtherapy is a mini-invasive, simple, safe, and effective methodfor the treatment of selected patients with HCH. | Yan Cui Li-Yan Zhou Man-Ku Dong Ping Wang Min Ji Xiao-Ou Li Chang-Wei Chen Zi-Pei Liu Yong-Jie Xu Hong-Wen Zhang Department of Hepatobiliary Surgery,Beijing 306 Hospital,Chaoyang District,Beijing 100101,China | 2003 | World Journal of Gastroenterology2003，9，9： | 43 |
| 2 | A series of Er3+-activated SrLaGa3O7 single crystal fibers for mid-infrared laser application显示文摘A multidisciplinary approach for the production and characterization of a series of high concentration Er3+activated SrLaGa3 O7(abbreviated as Er:SLGO)crystal fibers is shown to have a great promise for implementation in mid-infrared laser applications.The current approach includes the design and formation of unique layered tetrahedral network structures with several kinds of rare earth(RE)ions including Er ions distributing statistically between layers,such as Er:SLGO,Er,Nd:SLGO,Er,Yb,Ho:SLGO,Er,Eu:SLGO and Er,Ho:SLGO.Five kinds of Er:SLGO crystal fibers were designed to grow via a micropulling down method.Spectroscopic analyses show that Er,Yb,Ho:SLGO and Nd,Er:SLGO crystal fibers were superiorly endowed with inhomogeneous broadening absorption and strong emission.The unique structural components design enables the generation of improved absorption and emission recombination,and the inhibition of self-termination as well.Generally,the use of structural components design may warrant high-efficiency emissions in RE-doped crystal fibers. | Yan Wang Yingshu Lian Yanping Zhang Chaoyang Tu Dongfeng Xue | 2020 | Journal of Rare Earths2020，38，5： | 5 |
| 3 | A panel of monoclonal antibodies against the prion protein proves that there is no prion protein in human pancreatic ductal epithelial cells显示文摘Prion diseases are a group of neurodegenerative diseases that are fatal. The study of these unique diseases in China is hampered by a lack of resources. Amongst the most important resources for biological study are monoclonal antibodies. Here, we characterize a panel of monoclonal antibodies specific for cellular prion protein by enzyme-linked immunosorbent assay(ELISA), immunofluorescent staining, flow cytometry, and western blotting. We identify several antibodies that can be used for specific applications and we demonstrate that there is no prion protein expression in human pancreatic ductal epithelial cells(HPDC). | Liheng Yang Yan Zhang Lipeng Hu Ying Zhu Man-Sun Sy Chaoyang Li | 2014 | Virologica Sinica2014，29，4： | 3 |
| 4 | Cross-Scale Synthesis of Organic High-k Semiconductors Based on Spiro-Gridized Nanopolymers显示文摘High dielectric constants in organic semiconductors have been identified as a central challenge for the improvement in not only piexoelectric,preolecric,and freeltric efcts but also photoclecric conversion eficiency in OPVs,carrier mobility in OFETS,and charge density in charge-trapping memories.Herein,we report an ultralong persistence length(≈41 nm)efet of spiro-fused organic nanopolymers on dielectric properties,together with excitonic and charge carrier behaviors.The state-of-the-art nanopolymers,namely,nanopolyspirogrids(NPSGs),are synthesized via the simple crossscale Friedel-Crafts polygridlization of AjB-type nanomonomers.The high dielectric constant(k=8.43)of NPSG is firstly achieved by locking spiro-polygridization efect that results in the enhancement of dipole polarization.When doping into a polystyrene-based dielectric layer,such a high-k feature of NPSG increases the feld-ffct carrier mobility from 0.20 to 0.90cm^(2)Vl s'in pentacene OFET devices.Meanwhile,amorphous NPSG film exhibits an ultralow energy disorder(<50 meV)for an exellent zero-field hole mobility of 3.94×10^(-1)cm^(2)V^(-1)s^(-1).surpassing most of the amorphousπconjugated polymers Onganic nanopolymers with high dielectric constants open a new way to break through the bottleneck of eficiency and multifunctionality in the blueprint of the fourth generation semiconductors. | Dongqing Lin Wenhua Zhang Hang Yin Haixia Hu Yang Li He Zhang Le Wang Xinmiao Xie Hongkai Hu Yongxia Yan Haifeng Ling Jin'an Liu Yue Qian Lei Tang Yongxia Wang Chaoyang Dong Linghai Xie Hao Zhang Shasha Wang Ying Wei Xuefeng Guo Dan Lu Wei Huang | 2022 | Research2022，，2： | 3 |
| 5 | Prion protein and cancers显示文摘正常细胞的 prion 蛋白质, PrP C 是一高度在所有哺乳动物保存了并且广泛地表示了房间表面 glycoprotein。PrP 的表示是 prion 疾病的枢轴的 inthe 致病;然而, PrP C 遗体不完全地理解。在房间模型,基于研究功能的过多被归因于 PrP C 。在这份报纸,我们考察了潜在的角色那 PrP 在房间生理学的 C 戏并且集中了于它对 tumorigenesis 的贡献。 | Xiaowen Yang Yan Zhang Lihua Zhang Tianlin He Jie Zhang Chaoyang Li | 2014 | Acta Biochimica et Biophysica Sinica2014，46，6： | 3 |
| 6 | Structural and optical properties of Dy^(3+):YAlO3 phosphors for yellow light-emitting diode applications显示文摘The spectroscopic properties of a series of Dy^(3+)single-doped and Dy^(3+)/Nd^(3+),Dy^(3+)/Tb^(3+),and Dy^(3+)/Tm^(3+)co-doped YAlO_(3)(yttrium aluminum perovskite,YAP)phosphors were investigated and compared through the measurements of optical absorption,emission spectra,and fluorescence decay curves.For the Dy^(3+)ion single-doped samples,the intensity of each absorption band increases with an increment in Dy^(3+)ion doping concentration,and the identified strong absorption peak at 447 nm indicates that Dy^(3+):YAP phosphors are suitable to be pumped by a blue laser diode(LD).For all co-doped samples,absorption peaks of Dy^(3+)ion along with some of the absorption bands of Nd^(3+),Tb^(3+),and Tm^(3+)ions are observed.Under 351 and 447 nm excitation,a prominent emission peak at 572 nm was obtained in all the samples,corresponding to Dy^(3+):^(4)F_(9/2)→^(6)H_(13/2)transition.Here,2 at%Dy^(3+):YAP phosphor exhibits the highest yellow emission intensity under 447 nm pumping.Among the three kinds of Dy^(3+)co-doped phosphors,Dy^(3+)/Tb^(3+):YAP phosphor possesses the dominant yellow emission.The fluorescence decay curves show exponential behaviour and are fitted well.The Commission International de L’Eclairage(CIE)chromaticity coordinates were calculated following the respective emission spectra,and it is found that all the coordinates locate in the yellow region.The energy transfer(ET)processes were investigated and the concentration quenching mechanism was discussed.The obtained results suggest that Dy^(3+)-activated YAP phosphors are good candidates for yellow LED applications. | Yingshu Lian Yan Wang Jianfu Li Zhaojie Zhu Zhenyu You Chaoyang Tu Yadong Xu Wanqi Jie | 2021 | Journal of Rare Earths2021，39，8： | 2 |
| 7 | Classification and influencing factors of rural elderly's vulnerability to health-related poverty in central and western regions of China显示文摘Objective:To calculate the health poverty vulnerability index of elderly households in rural areas of central and western China,and then to classify these samples,lastly to decompose their influencing factors.Methods:First,based on survey data in 2018,the three-stage feasible generalized least squares was used to calculate the health poverty vulnerability index of elderly households,and then combined with whether the household income was below the poverty line and whether the family was healthy poverty vulnerability,the sample households were divided into four categories,and then used multiple unordered logistic regression to analyze various types of influencing factors,and finally used the Shapley index to decompose the contribution of each influencing factor.Results:The average vulnerability of health poverty was 0.5979±0.25199,with 1169 households greater than or equal to 0.5,accounting for 63.26%;the number of households stuck in poverty,temporary poverty,potential poverty,and escaped from poverty were 489,300,680,and 379 households,accounting for 26.46%,16.23%,36.80%,and 20.51%of the total sample;compared with escaped from poverty families,the three variables of marital status,the number of chronically ill patients,and the number of annual hospitalizations were the common influencing factors of other three types families;The Shapley decomposition showed that the interviewees’education level and family members engaged in non-agricultural work have contributed significantly to the three types,however two indicators:time required to visit a medical institution and self-assessment of health status of the main interviewees showed great differences in different types of families.Conclusion:Rural elderly households have a high level of vulnerability to health poverty;potential poverty households and persistent poverty households account for a large proportion,and continuous intervention should be carried out;it is necessary to unify the implementation of basic poverty alleviation work,but also to enhance refined management capabilities and adopt differentiated intervention measures. | Qin Xiang Chaoyang Yan Ying Ma Hui Liao Jing Wang | 2021 | Global Health Journal2021，5，3： | 2 |
| 8 | Automatic extraction of power lines from aerial images显示文摘 | YAN Guangjian L1 Chaoyang ZHOU Guoqing | 2007 | IEEE Geoscience and Remote Sensing Letters2007，4，3： | 1 |
| 9 | The Growth and Spectroscopic Characteristics of Ca3Y2(BO3)4:Tm3+ Crystal 显示文摘 | Tu Chaoyang Wang Yan | 2004 | Journal of Alloys and Compounds2004，368，： | 1 |
| 10 | Innervation of cervical ventral facet joint capsule: Histological evidence显示文摘AIM: To assess the presence of nerves in ventral facet joint capsules as facet capsules are generally implicated in neck pain.METHODS: Twenty-four ventral cervical facet joint capsules were harvested from 3 unembalmed cadavers. Paraffin sections from these capsules were processed to identify neurofilament and substance P immunoreactive fibers. Nerve fiber presence was also verified by a silver impregnation method.RESULTS: Neurofilament reactive fibers were observed in sections from 9 capsules. They were observed in areas with collagen fibers and areas with irregular connective tissue. Substance P reactive nerve fibers were found in sections from 7 capsules in similar areas. Silver impregnation also revealed the presence of nerve fibers. The nerve fibers were also found as bundles in the lateral margins of the capsule. A Pacinian corpuscle-like ending was also observed in onespecimen.CONCLUSION: Nerve fibers revealed by neurofilament immunoreactivity and silver staining support innervation of the ventral aspect of the facet joint capsule. The presence of substance P reactive fibers supports the potential role of these elements in mediating pain. The presence of a Pacinian-like ending implicates a potential role in joint movement. | Srinivasu Kallakuri Yan Li Chaoyang Chen John M Cavanaugh | 2012 | World Journal of Orthopedics2012，3，2： | 1 |
| 11 | The Growth and Spectroscopic Characteristics of Ca3Y2(BO3)4:Er3+ Laser Crystal显示文摘 | Tu Chaoyang Wang Yan | 2004 | Journal of Crystal Growth2004，260，： | 1 |
| 12 | Identification of LepA as PPIase reveals a common molecular mechanism of translational GTPases regulating L11 switch on the ribosome显示文摘LepA, the highly conserved translational GTPase (trGTPase), triggers one-codon back-movement of the elongating ribosome. Here we identify a new enzymatic activity | Yan Qin Institute of Biophysics, Chinese, 15 Datun Road, Chaoyang District, Beijing, 100101, China | 2009 | 生物物理学报2009，25，S1： | 0 |
| 13 | Habitat Influence on the Molecular, Carbon and Hydrogen Isotope Compositions of Leaf Wax n-Alkanes in a Subalpine Basin, Central China显示文摘Epidermal leaf waxes of terrestrial higher plants have been widely utilized for the reconstructions of paleoenvironment and paleoclimate in peat deposits. In this study, specimens of four plant species growing in both peatland and non-peatland habitats were retrieved to compare their molecular, carbon(δ13 C) and hydrogen(δ2 H) isotopic compositions of leaf wax n-alkanes from a closed subalpine basin in Central China. Three of the four species show quite higher total concentrations of n-alkanes in the relatively dry non-peatland setting than in the peatland. In addition, the δ2 H values of long-chain n-alkanes are generally less depleted in the peatland and are comparable among different plant species, which is interpreted as the influence of inundation condition and the possible limited supply of photosynthetic products. This study reveals different patterns of plant wax molecular and isotopic compositions between peatland and the surrounding non-peatland conditions, and confirms the paleoenvironmental potential of leaf wax ratios on the peat sequences. | Chaoyang Yan Yiming Zhang Yanzhen Zhang Zhiqi Zhang Xianyu Huang | 2020 | Journal of Earth Science2020，31，4： | 0 |
| 14 | Are our clone detectors good enough?An empirical study of code effects by obfuscation显示文摘Clone detection has received much attention in many fields such as malicious code detection,vulnerability hunting,and code copyright infringement detection.However,cyber criminals may obfuscate code to impede violation detection.To date,few studies have investigated the robustness of clone detectors,especially in-fashion deep learning-based ones,against obfuscation.Meanwhile,most of these studies only measure the difference between one code snippet and its obfuscation version.However,in reality,the attackers may modify the original code before obfuscating it.Then what we should evaluate is the detection of obfuscated code from cloned code,not the original code.For this,we conduct a comprehensive study evaluating 3 popular deep-learning based clone detectors and 6 commonly used traditional ones.Regarding the data,we collect 6512 clone pairs of five types from the dataset BigCloneBench and obfuscate one program of each pair via 64 strategies of 6 state-of-art commercial obfuscators.We also collect 1424 non-clone pairs to evaluate the false positives.In sum,a benchmark of 524,148 code pairs(either clone or not)are generated,which are passed to clone detectors for evaluation.To automate the evaluation,we develop one uniform evaluation framework,integrating the clone detectors and obfuscators.The results bring us interesting findings on how obfuscation affects the performance of clone detection and what is the difference between traditional and deep learning-based clone detectors.In addition,we conduct manual code reviews to uncover the root cause of the phenomenon and give suggestions to users from different perspectives. | Weihao Huang Guozhu Meng Chaoyang Lin Qiucun Yan Kai Chen Zhuo Ma | 2023 | Cybersecurity2023，6，4： | 0 |
| 15 | Merger Risk Assessment Using Grey Method显示文摘 | Chaoyang Xu Xing Yan | 2004 | China-USA Business Review2004，3，1： | 0 |
| 16 | pIIIA/N2期非小细胞肺癌患者外科治疗的预后分析(英文)显示文摘Objective: The aim of the study was to identify prognostic factors in non-small-cell lung cancer (NSCLC) with N2 nodal involvement.Methods: A retrospective analysis of disease free survival and 5-year survival for NSCLC patients who underwent primary surgical resection without neoadjuvant chemotherapy were performed.Between January 1998 and May 2004,133 patients were enrolled.Several factors such as age,sex,skip metastasis,number of N2 lymph node stations,type of resection,histology,adjuvant therapy etc.,were recorded and analyzed.SPSS 16.0 software was used.Results: Overall 5-year survival for 133 patients was 32.33%,5-year survival for single N2 station and multiple N2 stations sub-groups were 39.62% and 27.50% respectively,and 5-year survival for cN0–1 and cN2 sub-groups were 37.78% and 20.93% respectively.COX regression analysis revealed that number of N2 station (P = 0.013,OR: 0.490,95% CI: 0.427–0.781) and cN status (P = 0.009,OR: 0.607,95% CI: 0.372–0.992) were two favorable prognostic factors of survival.Conclusion: Number of N2 station and cN status were two favorable prognostic factors of survival.In restrict enrolled circumstances,after combined therapy made up of surgery and postoperative adjuvant therapy have been performed,satisfied survival could be achieved. | Zhenrong Zhang Deruo Liu Yongqing Guo Bin Shi Yanchu Tian Zhiyi Song Yanning Shou Haitao Zhang Chaoyang Liang Zaiyong Wang Tong Bao Qjanli Ma | 2011 | The Chinese-German Journal of Clinical Oncology2011，10，1： | 0 |
| 17 | BRI's Glorious Chapter for Energy Cooperation显示文摘Since the Belt and Road Initiative(BRI)was put forward by Chinese President Xi Jinping in 2013,the PetroChina Great Wall Drilling Co.,Ltd.(GWDC)has been working in over 33 countries in Africa,Central Asia,the Middle East and America,providing engineering and technical services to 130-plus overseas customers. | Zhang Chaoyang Liu Yan | 2023 | China News Release2023，，4： | 0 |
| 18 | The substitution V379I in PA protein attenuates the pathogenicity of influenza A(H1N1)pdm09 viruses in mice显示文摘Dear Editor,Since August 2010,the world was in the post-pandemic period and the influenza A(H1N1)pdm09(pdmH1N1)virus co-circulated with H3N2 and B virus seasonally(WHO,2010).The continuous surveillance on the pdmH1N1 virus in the post-pandemic period was recommended by WHO.In order to detect unusual events that might indicate a shift in severity disease,or emergence of a new virus,we collected a total of 312 throat swabs of laboratory-confirmed pdmHlNl patients from Hunan and Jilin provinces in | Yongkun Chen Wenfei Zhu Tian Bai Xiaohui Zou Siyu Zhang Yan Sun Xiyan Li XingyYu Xiang Qinglong Zhao Chaoyang Huang Tao Chen Dayan Wang Yuelong Shu | 2017 | Science China(Life Sciences)2017，60，9： | 0 |
| 19 | Deciphering transcriptome alterations in bone marrow hematopoiesis at single-cell resolution in immune thrombocytopenia显示文摘Immune thrombocytopenia(ITP)is an autoimmune disorder,in which megakaryocyte dysfunction caused by an autoimmune reaction can lead to thrombocytopenia,although the underlying mechanisms remain unclear.Here,we performed single-cell transcriptome profiling of bone marrow CD34+hematopoietic stem and progenitor cells(HSPCs)to determine defects in megakaryopoiesis in ITP.Gene expression,cell-cell interactions,and transcriptional regulatory networks varied in HSPCs of ITP,particularly in immune cell progenitors.Differentially expressed gene(DEG)analysis indicated that there was an impaired megakaryopoiesis of ITP.Flow cytometry confirmed that the number of CD9+and HES1+cells from Lin−CD34+CD45RA−HSPCs decreased in ITP.Liquid culture assays demonstrated that CD9+Lin−CD34+CD45RA−HSPCs tended to differentiate into megakaryocytes;however,this tendency was not observed in ITP patients and more erythrocytes were produced.The percentage of megakaryocytes differentiated from CD9+Lin−CD34+CD45RA−HSPCs was 3-fold higher than that of the CD9−counterparts from healthy controls(HCs),whereas,in ITP patients,the percentage decreased to only 1/4th of that in the HCs and was comparable to that from the CD9−HSPCs.Additionally,when co-cultured with pre-B cells from ITP patients,the differentiation of CD9+Lin−CD34+CD45RA−HSPCs toward the megakaryopoietic lineage was impaired.Further analysis revealed that megakaryocytic progenitors(MkP)can be divided into seven subclusters with different gene expression patterns and functions.The ITP-associated DEGs were MkP subtype-specific,with most DEGs concentrated in the subcluster possessing dual functions of immunomodulation and platelet generation.This study comprehensively dissects defective hematopoiesis and provides novel insights regarding the pathogenesis of ITP. | Yan Liu Xinyi Zuo Peng Chen Xiang Hu Zi Sheng Anli Liu Qiang Liu Shaoqiu Leng Xiaoyu Zhang Xin Li Limei Wang Qi Feng Chaoyang Li Ming Hou Chong Chu Shihui Ma Shuwen Wang Jun Peng | 2022 | Signal Transduction and Targeted Therapy2022，7，11： | 0 |
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