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| 1 | Improved TQWT for marine moving target detection显示文摘Under the conditions of strong sea clutter and complex moving targets,it is extremely difficult to detect moving targets in the maritime surface.This paper proposes a new algorithm named improved tunable Q-factor wavelet transform(TQWT)for moving target detection.Firstly,this paper establishes a moving target model and sparsely compensates the Doppler migration of the moving target in the fractional Fourier transform(FRFT)domain.Then,TQWT is adopted to decompose the signal based on the discrimination between the sea clutter and the target’s oscillation characteristics,using the basis pursuit denoising(BPDN)algorithm to get the wavelet coefficients.Furthermore,an energy selection method based on the optimal distribution of sub-bands energy is proposed to sparse the coefficients and reconstruct the target.Finally,experiments on the Council for Scientific and Industrial Research(CSIR)dataset indicate the performance of the proposed method and provide the basis for subsequent target detection. | PAN Meiyan SUN Jun YANG Yuhao LI Dasheng XIE Sudao WANG Shengli CHEN Jianjun | 2020 | Journal of Systems Engineering and Electronics2020，31，3： | 6 |
| 2 | Adenosine A 2A R modulates cardiovascular function by activating ERK1/2 signal in the rostral ventrolateral medulla of acute myocardial ischemic rats显示文摘 | Meiyan Jiang Chengrong Zhang Jin Wang Jun Chen Chunmei Xia Dongshu Du Na Zhao Yinxiang Cao Linlin Shen Danian Zhu | 2011 | Life Sciences2011，，5： | 4 |
| 3 | The IAA-and ABA-responsive transcription factor CgMYB58 upregulates lignin biosynthesis and triggers juice sac granulation in pummelo显示文摘In citrus,lignin overaccumulation in the juice sac results in granulation and an unpleasant fruit texture and taste.By integrating metabolic phenotyping and transcriptomic analyses,we found 702 differentially expressed genes(DEGs),including 24 transcription factors(TFs),to be significantly correlated with lignin content.CgMYB58 was further identified as a critical R2R3 MYB TF involved in lignin overaccumulation owing to its high transcript levels in Huanong Red-fleshed pummelo(HR,Citrus grandis)fruits.Transient expression of CgMYB58 led to an increase in the lignin content in the pummelo fruit mesocarp,whereas its stable overexpression significantly promoted lignin accumulation and upregulated 19 lignin biosynthetic genes.Among these genes,CgPAL1,CgPAL2,Cg4CL1,and CgC3H were directly modulated by CgMYB58 through interaction with their promoter regions.Moreover,we showed that juice sac granulation in pummelo fruits could be affected by indole-3-acetic acid(IAA)and abscisic acid(ABA)treatments.In HR pummelo,ABA significantly accelerated this granulation,whereas IAA effectively inhibited this process.Taken together,these results provide novel insight into the lignin accumulation mechanism in citrus fruits.We also revealed the theoretical basis via exogenous IAA application,which repressed the expression of CgMYB58 and its target genes,thus alleviating juice sac granulation in orchards. | Meiyan Shi Xiao Liu Haipeng Zhang Zhenyu He Hongbin Yang Jiajing Chen Jia Feng Wenhui Yang Youwu Jiang Jia-Long Yao Cecilia Hong Deng Juan Xu | 2020 | Horticulture Research2020，7，1： | 4 |
| 4 | Dielectric metalens for miniaturized imaging systems:progress and challenges显示文摘Lightweight, miniaturized optical imaging systems are vastly anticipated in these fields of aerospace exploration, industrial vision, consumer electronics, and medical imaging. However, conventional optical techniques are intricate to downscale as refractive lenses mostly rely on phase accumulation. Metalens, composed of subwavelength nanostructures that locally control light waves, offers a disruptive path for small-scale imaging systems. Recent advances in the design and nanofabrication of dielectric metalenses have led to some high-performance practical optical systems. This review outlines the exciting developments in the aforementioned area whilst highlighting the challenges of using dielectric metalenses to replace conventional optics in miniature optical systems. After a brief introduction to the fundamental physics of dielectric metalenses, the progress and challenges in terms of the typical performances are introduced. The supplementary discussion on the common challenges hindering further development is also presented, including the limitations of the conventional design methods, difficulties in scaling up, and device integration. Furthermore, the potential approaches to address the existing challenges are also deliberated. | Meiyan Pan Yifei Fu Mengjie Zheng Hao Chen Yujia Zang Huigao Duan Qiang Li Min Qiu Yueqiang Hu | 2022 | Light(Science & Applications)2022，11，8： | 3 |
| 5 | Carrier-free highly drug-loaded biomimetic nanosuspensions encapsulated by cancer cell membrane based on homology and active targeting for the treatment of glioma显示文摘Nanosuspensions,as a new drug delivery system for insoluble drugs,are only composed of a drug and a small amount of stabilizer,which is dispersed in an aqueous solution with high drug-loading,small particle size,high dispersion,and large specific surface area.It can significantly improve the dissolution,bioavailability,and efficacy of insoluble drugs.In this study,paclitaxel nanosuspensions((PTX)NS)were prepared by an ultrasonic precipitation method,with the characteristics of simple preparation and easy repetition.With the help of a homologous targeting mechanism,a kind of glioma C6 cancer cell membrane(CCM)-coated(PTX)NS was developed and modified with DWSW peptide to obtain DWSW-CCM-(PTX)NS with the functions of BBB penetration and tumor targeting.The results showed that the cancer cell membrane could effectively camouflage the nanosuspensions so that it was not cleared by the immune system and could cross the blood-brain-barrier(BBB)and selectively target tumor tissues.Cell uptake experiments and in vivo imaging confirmed that the uptake of DWSW-CCM-(PTX)NS by tumor cells and the distribution in intracranial gliomas increased.Cytotoxicity test and in vivo anti-glioma studies showed that DWSW-CCM-(PTX)NS could significantly inhibit the growth of glioma cells and significantly prolong the survival time of glioma-bearing mice.Finally,the cancer cell membrane coating endowed the nanosuspensions with the biological properties of homologous adhesion and immune escape.This study provides an integrated solution for improving the targeting of nanosuspensions and demonstrates the encouraging potential of biomimetic nanosuspensions applicable to tumor therapy. | Yueyue Fan Yuexin Cui Wenyan Hao Mengyu Chen Qianqian Liu Yuli Wang Meiyan Yang Zhiping Li Wei Gong Shiyong Song Yang Yang Chunsheng Gao | 2021 | Bioactive Materials2021，6，12： | 3 |
| 6 | The analysis of trans fatty acid profiles in deep frying palm oil and chicken fillets with an improved gas chromatography method显示文摘 | Yi Chen Ying Yang Shaoping Nie Xi Yang Yuting Wang Meiyan Yang Chang Li Mingyong Xie | 2014 | Food Control2014，，： | 2 |
| 7 | Cloning of a Putative Pheromone Receptor Gene Fragment from Lentinula edodes显示文摘A 508 bp fragment of a putative pheromone receptor gene from Lentinula edodes was amplified by PCR using a pair of degenerate primers designed according to conserved sequences of pheromone receptor genes reported in other Basidiomycetes.The fragment encodes 117 amino acids and contains three introns,56 bp,51 bp and 50 bp in size.Alignment analysis revealed that the deduced amino acid sequence of the L.edodes fragment exhibited 65% identity and 82% similarity with the corresponding segments of pheromone receptors reported in Coprinus cinereus and Schizophyllum commune. | BAO Dapeng ZHANG Meiyan LI Su CHEN Mingjie | 2008 | 食用菌学报2008，15，2： | 2 |
| 8 | Mycorrhizal Synthesis Involving Boletus edulis and Pinus massoniana显示文摘Mycorrhizae involving Boletus edulis and Pinus massoniana have been successfully established and their morphological characteristics described.Optimal conditions for mycorrhizal synthesis were determined using orthogonal testing of three parameters:substrate,age of host plant and inoculation procedure.Following integration analysis of plant survival rates,diameter of seedling rootstock,height of seedling shoot,number of mycorrhizae,ratio of shoot/root biomass,number of mycorrhizae,and the ratio of infected/non-infected root tips,we concluded that a double-layered growth substrate that simulated natural soil structure was superior for mycorrhizal synthesis compared with the more commonly used single-layered peat moss and vermiculite substrate,especially when sepiolite powder was also added. | FU Shaochun TAN Qi CHEN Mingjie SHANG Xiaodong CAI Lingyi ZHANG Meiyan | 2009 | 食用菌学报2009，16，1： | 2 |
| 9 | Effect of anaerobic reaction time on denitrifying phosphorus removal and N 2 O production显示文摘 | Yayi Wang Junjun Geng Zhongjia Ren Weitao He Meiyan Xing Min Wu Shaowei Chen | 2011 | Bioresource Technology2011，，10： | 1 |
| 10 | Preventive effect of nasal Timosaponin BII-loaded temperature-/ionsensitive in situ hydrogels on Alzheimer’s disease显示文摘Objective:To study the preventive effect of Timosaponin BII(T-BII)-loaded temperature/ion-sensitive nasal in situ hydrogels(ISGs)on Alzheimer's disease(AD),its preparation technology,characteristics and in vivo effects were evaluated.Methods:The morphological and rheological properties were evaluated.The preventive effects of T-BII ISG on scopolamine-induced AD in mice were determined with the index of muscarinicreceptor 1(M1)expression and pathological changes.Results:Results revealed that T-BII ISG significantly increased the content of M1 choline receptors in the hippocampus of mice and ameliorated the damage incurred to the hippocampal cornu ammonis 1(CA1)area.Conclusion:T-BII ISGs is a reasonable and convenient method of exerting an obvious preventive effect on mice with AD induced by scopolamine.This,thereby,lays forth a new treatment option for preventing AD. | Ge Ou Wenyuan Chen Meiyan Yang Qian Li Yuanyuan Zhang Delian Wan Lina Du Baiping Ma | 2021 | Journal of Traditional Chinese Medical Sciences2021，8，1： | 1 |
| 11 | Identification of A Novel SBF2 Frameshift Mutation in Charcot–Marie–Tooth Disease Type 4B2 Using Whole-exome Sequencing显示文摘Charcot–Marie–Tooth disease type 4B2 with early-onset glaucoma(CMT4B2, OMIM604563) is a genetically-heterogeneous childhood-onset neuromuscular disorder. Here, we report the case of a 15-year-old male adolescent with lower extremity weakness, gait abnormalities, foot deformities and early-onset glaucoma. Since clinical diagnosis alone was insufficient for providing pathogenetic evidence to indicate that the condition belonged to a consanguineous family, we applied whole-exome sequencing to samples from the patient, his parents and his younger brother,assuming that the patient's condition is transmitted in an autosomal recessive pattern. A frame-shift mutation, c.4571 del G(P.Gly1524Glufs*42), was revealed in the CMT4B2-related gene SBF2(also known as MTMR13, MIM 607697), and this mutation was found to be homozygous in the proband and heterozygous in his parents and younger brother. Together with the results of clinical diagnosis,this case was diagnosed as CMT4B2. Our finding further demonstrates the use of whole-exome sequencing in the diagnosis and treatment of rare diseases. | Meiyan Chen Jing Wu Ning Liang Lihui Tang Yanhua Chen Huishuang Chen Wei Wei Tianying Wei Hui Huang Xin Yi Ming Qi | 2014 | Genomics, Proteomics & Bioinformatics2014，12，5： | 1 |
| 12 | 显示文摘 | Zhan Meiyan Chen Zhenhua Yan Hongge | 2007 | Journal of Materials Processing Technology2007，182，： | 1 |
| 13 | Red soil for sediment capping to control the internal nutrient release under flow conditions显示文摘 | Lei Xia Guo Liu Chunmei Chen Meiyan Wen Yangyang Gao | 2016 | Frontiers of Environmental Science & Engineering2016，10，6： | 1 |
| 14 | Cloning of le-pyrG, an Orotidine-5'-monophosphate Decarboxylase Encoding Gene from Lentinula edodes显示文摘 | BAO Dapeng FENG Aiping ZHANG Meiyan TAN Qi CHEN Mingjie NIU Liying PAN Yingjie | 2009 | 食用菌学报2009，16，2： | 1 |
| 15 | 显示文摘 | Zhang Yanghuan Chen Meiyan Wang Xinlin | 2004 | J Power Sources2004，125，： | 1 |
| 16 | 显示文摘 | Zhang Yanghuan Chen Meiyan Dong Xiaoping | 2004 | J Alloys Comp2004，376，： | 1 |
| 17 | 显示文摘 | Zhang Yanghuan Chen Meiyan Wang Xinlin | 2003 | J Power Sources2003，125，： | 1 |
| 18 | 显示文摘 | Zhang Yanghuan Chen Meiyan Wan Xinlin | 2004 | Electrochima Acta2004，49，： | 1 |
| 19 | Two novel rolling processes of porous metal performs prepared by spray deposition technique using conventional roiling mill 显示文摘 | Zhan Meiyan Chen Zhenhua Yan Hongge | 2008 | Journal of materials processing technology2008，202，： | 1 |
| 20 | Streamflow simulation by SWAT using different precipitation sources in large arid basins with scarce raingauges显示文摘 | YU Meiyan CHEN Xi LI Lanhai | 2011 | Water Resources Management2011，25，11： | 1 |
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