|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | A Review of Seasonal Climate Prediction Research in China显示文摘The ultimate goal of climate research is to produce climate predictions on various time scales. In China, efforts to predict the climate started in the 1930 s. Experimental operational climate forecasts have been performed since the late 1950 s,based on historical analog circulation patterns. However, due to the inherent complexity of climate variability, the forecasts produced at that time were fairly inaccurate. Only from the late 1980 s has seasonal climate prediction experienced substantial progress, when the Tropical Ocean and Global Atmosphere project of the World Climate Research program(WCRP) was launched. This paper, following a brief description of the history of seasonal climate prediction research, provides an overview of these studies in China. Processes and factors associated with the climate variability and predictability are discussed based on the literature published by Chinese scientists. These studies in China mirror aspects of the climate research effort made in other parts of the world over the past several decades, and are particularly associated with monsoon research in East Asia. As the climate warms, climate extremes, their frequency, and intensity are projected to change, with a large possibility that they will increase. Thus, seasonal climate prediction is even more important for China in order to effectively mitigate disasters produced by climate extremes, such as frequent floods, droughts, and the heavy frozen rain events of South China. | WANG Huijun FAN Ke SUN Jianqi LI Shuanglin LIN Zhaohui ZHOU Guangqing CHEN Lijuan LANG Xianmei LI Fang ZHU Yali CHEN Hong ZHENG Fei | 2015 | Advances in Atmospheric Sciences2015，32，2： | 20 |
| 2 | Hypocrellin A-based photodynamic action induces apoptosis in A549 cells through ROS-mediated mitochondrial signaling pathway显示文摘Over recent decades, many studies have reported that hypocrellin A(HA) can eliminate cancer cells with proper irradiation in several cancer cell lines. However, the precise molecular mechanism underlying its anticancer effect has not been fully defined. HA-mediated cytotoxicity and apoptosis in human lung adenocarcinoma A549 cells were evaluated after photodynamic therapy(PDT). A temporal quantitative proteomics approach by isobaric tag for relative and absolute quantitation(iTRAQ) 2 D liquid chromatography with tandem mass spectrometric(LC–MS/MS) was introduced to help clarify molecular cytotoxic mechanisms and identify candidate targets of HA-induced apoptotic cell death. Specific caspaseinhibitors were used to further elucidate the molecular pathway underlying apoptosis in PDT-treated A549 cells. Finally, down-stream apoptosis-related protein was evaluated. Apoptosis induced by HA was associated with cell shrinkage, externalization of cell membrane phosphatidylserine, DNA fragmentation,and mitochondrial disruption, which were preceded by increased intracellular reactive oxygen species(ROS) generations. Further studies showed that PDT treatment with 0.08 mmol/L HA resulted in mitochondrial disruption, pronounced release of cytochrome c, and activation of caspase-3,-9, and-7.Together, HA may be a possible therapeutic agent directed toward mitochondria and a promising photodynamic anticancer candidate for further evaluation. | Shanshan Qi Lingyuan Guo Shuzhen Yan Robert J.Lee Shuqin Yu Shuanglin Chen | 2019 | Acta Pharmaceutica Sinica B2019，9，2： | 12 |
| 3 | Recent advances in the role of toll-like receptors and TLR agonists in immunotherapy for human glioma显示文摘Gliomas 是有很差的预后的极其好攻击的大脑肿瘤。为人的 gliomas 的处理的更有希望的策略之一是对肿瘤唯一的抗原被利用产生疫苗的指向的免疫疗法。然而,途径由由创造一个免疫者的那人的 gliomas 逃跑免疫者监视压制了微型环境的事实是复杂的。为了反对 glioma,强加了作为辅助涉及成熟,扩大,和移植在集中的临床的调查下面的有免疫力的房间的有免疫力的抑制,分子和小径治疗。像使用费的受体(TLR ) 调停因此,许多在有免疫力的房间类型,和 TLR 收缩筋的这些功能当前是在许多癌症要用作重要助手的主要候选人分子。在为 glioma 的动物模型, TLR 收缩筋由便于抗原表示并且刺激天生、适应的免疫展出了 antitumor 性质。在临床的试用,几 TLR 收缩筋完成了幸存利益,并且许多更多的试用正在招募或进行中。然而,复杂化因素的一秒是 TLR 也在他们能在包括细胞生长,增长,侵略,移植,和甚至干细胞维护支持活动的许多肿瘤相反参与的癌症细胞上被表示。因此, TLR 收缩筋能可能在肿瘤生物学起双作用。这里, TLR 和 TLR 收缩筋怎么在 glioma 生物学并且在 anti-glioma 治疗工作,被总结以为免疫疗法提供与免疫系统和含意的 glioma 的复杂关系的一幅当前的图画。 | Shuanglin Deng Shan Zhu Yuan Qiao Yong-Jun Liu Wei Chen Gang Zhao Jingtao Chen | 2014 | Protein & Cell2014，5，12： | 6 |
| 4 | A Comparison of the Effects of Interannual Arctic Sea Ice Loss and ENSO on Winter Haze Days: Observational Analyses and AGCM Simulations显示文摘This study compares the impacts of interannual Arctic sea ice loss and ENSO events on winter haze days in China's Mainland through observational analyses and AGCM sensitivity experiments. The results suggest that(1) Arctic sea ice loss favors an increase in haze days in central–eastern China;(2) the impact of ENSO is overall contained within southern China, with increased(reduced) haze days during La Ni?a(El Ni?o) winters; and(3) the impacts from sea ice loss and ENSO are linearly additive. Mechanistically, Arctic sea ice loss causes quasi-barotropic positive height anomalies over the region from northern Europe to the Ural Mountains(Urals in brief) and weak and negative height anomalies over the region from central Asia to northeastern Asia. The former favors intensified frequency of the blocking over the regions from northern Europe to the Urals, whereas the latter favors an even air pressure distribution over Siberia, Mongolia, and East Asia. This large-scale circulation pattern favors more frequent occurrence of calm and steady weather in northern China and, as a consequence, increased occurrence of haze days. In comparison,La Ni?a(El Ni?o) exerts its influence along a tropical pathway by inducing a cyclonic(anticyclonic) lower-tropospheric atmospheric circulation response over the subtropical northwestern Pacific. The northeasterly(southwesterly)anomaly at the northwestern rear of the cyclone(anticyclone) causes reduced(intensified) rainfall over southeastern China, which favors increased(reduced) occurrence of haze days through the rain-washing effect. | Shuanglin LI Zhe HAN Huopo CHEN | 2017 | Journal of Meteorological Research2017，31，5： | 6 |
| 5 | KCTDIO is critical for heart and blood vessel development of zebrafish显示文摘 | Xiang Hu Shiquan Gan Guie Xie Li Li Cheng Chen Xiaofeng Ding Mei Han Shuanglin Xiang Jian Zhang | 2014 | Acta Biochimica et Biophysica Sinica2014，46，5： | 4 |
| 6 | Roles of various Ni species on TiO2 in enhancing photocatalytic H2 evolution显示文摘Low-cost nickels can be used as cocatalyst to improve the performance of photocatalysts,which may be promising materials applied in the field of photocatalytic water splitting.In this study,different nickel species Ni,Ni(OH)2,NiO,NiOx,and NiS are used to modified titanium dioxide(P25)to investigate their roles on the photocatalytic hydrogen evolution activities.UV-visible,X-ray diffraction(XRD),Brunner-Emmet-Teller(BET)measurements,transmission electron microscopy(TEM),X-ray photoelectron spectroscopy(XPS)analysis etc.are employed to characterize the physical and chemical properties of catalysts.The results indicate that all the nickel species can improve the photocatalytic hydrogen production activity of P25.The P25 modified with NiOx and NiS has more superior photocatalytic hydrogen evolution activities than those modified with other nickel species.The reason for this is that NiOx and NiS can form p-n junctions with P25 respectively.In addition,NiOx can be selectively deposited on the active sites of P25 via in situ the photodeposition method and NiS is beneficial for H+reacting with photo-excited electrons. | Xiaoping CHEN Jihai XIONG Jinming SHI Song XIA Shuanglin GUI Wenfeng SHANGGUAN | 2019 | Frontiers in Energy2019，13，4： | 2 |
| 7 | Pilomyxoid Astrocytoma in Cerebellum显示文摘Pilomyxoid astrocytoma is a new identified variant type of pilocytic astrocytoma,and typically locates in the hypothalamic and chiasmatic region.Herein,we reported a nine-year-old boy with pilomyxoid astrocytoma in the cerebellum.MRI scanning showed a tumor involved the cerebellar vermis,tonsil,the forth ventricle and brainstem.It was homogeneous isointensity on T1WI,relative hyper-intensity on T2WI,hyper-intensity on fluid attenuated inversion recovery (FLAIR) images,and uniform enhancement on contrast T1WI.The tumor was sub-totally removed and was proved histologically to be pilomyxoid astrocytoma.Follow-up at the 5th month,MRI showed the residual tumor enlarged at the brainstem.The patient survived 10 months after the operation,and finally died of respiration failure resulting from brainstem dysfunction. | Peng-fei Ge Hai-feng Wang Li-mei Qu Bo Chen Shuanglin Fu Yinan Luo | 2011 | Chinese Journal of Cancer Research2011，23，3： | 2 |
| 8 | Involvement of post?transcriptional regulation of FOXO1 by HuR in 5?FU?inducedapoptosis in breast cancer cells显示文摘 | Yunbo Li Jinhai Yu Danhua Du Shuanglin Fu Ye Chen Fang Yu Peng Gao | 2013 | Oncology Letters2013，，1： | 2 |
| 9 | 秦岭山区粘菌纲菌物名录(英文) | Chen Shuanglin 1 Li Yu 2 Zhang Xianchun 3 (1.Institute of Microbiology,Academia Sinica,Beijing 100080 2.Jilin Agricultural University 3.Institute of Botany,Academia Sinica) | 1999 | 安徽农业大学学报1999，26，3： | 1 |
| 10 | Phase diagram calculation:past,present and future显示文摘 | Chang Y Austin Chen Shuanglin Zhang Fan | 2004 | Prog in Mater Sci2004，49，34： | 1 |
| 11 | Structural changes of a bacteriophage upon DNA packaging and maturation显示文摘Dear Editor,Tailed,double-stranded DNA(dsDNA)bacteriophages,which belong to the order of Caudovirales,have a tail attached to a pentameric vertex of the icosahedral capsid shell(head)through a 12-fold portal(Johnson and Chiu,2007).The phages package genomic dsDNA into a round procapsid using the portal in complex with an ATP-dependent terminase complex as the motor.During packaging,the procapsid shell expands to a more angular intermediate to match the size of the viral genome(Guo et al.,2014).When the phage head is full,the portal detects internal pressure and conveys a signal from the inner capsid to the exterior,which triggers a sequence of events-the terminase complex cleaving mature DNA genome from a multi-genome concatemer,the release of the terminase complex from the portal,and the attachment of the tail complex-in the completion of phage assembly(Lander et al.,2006;Johnson and Chiu,2007).At the beginning of phage infection,the tail is responsible for receptor recognition,and the portal and tail act as a tunnel for DNA delivery into the host cytoplasm(Johnson and Chiu,2007).These mechanisms of DNA packaging and ejection may also be conserved in many other DNA viruses,including herpesvirus(Wang et al.,2020;Yang et al.,2020). | Wenyuan Chen Hao Xiao Xurong Wang Shuanglin Song Zhen Han Xiaowu Li Fan Yang Li Wang Jingdong Song Hongrong Liu Lingpeng Cheng | 2020 | Protein & Cell2020，11，5： | 1 |
| 12 | Phase diagram calculation: Past, present and future 显示文摘 | Austin Chang Y Shuanglin Chen Fan Zhang | 2004 | Prog Ma- ter Sci2004，49，： | 1 |
| 13 | Notes on Myx- omycetes from Qinghai, China 显示文摘 | Yah ShuZhen Liu QiSha Chen ShuangLin | 2010 | Myeosystema2010，29，6： | 1 |
| 14 | An analysis of the genetic diversity and genetic structure of Eucommia ulmoides u- sing inter - simple sequence repeat ( ISSR ) markers 显示文摘 | Wu Mingqian Chen Shuanglin Wang Meixia | 2011 | African Journal of Biotechnology2011，10，19： | 1 |
| 15 | Phase diagram calculation: past, present and future显示文摘 | Y.Austin Chang Shuanglin Chen Fan Zhang Xinyan Yan Fanyou Xie Rainer Schmid-Fetzer W.Alan Oates | 2003 | Progress in Materials Science2003，，3： | 1 |
| 16 | Feasibility Study on the Controlled Hydriding Com- bustion Synthesis of Mg-La-Ni Ternary Hydrogen Storage Composite 显示文摘 | Li Qian Lu Xionggang Chou Kuochih Xu Kuangdi Zhang Jieyu Chen Shuanglin | 2007 | Inter J Hydrogen Energy2007，32，： | 1 |
| 17 | Effect of process conditions on the synthesis of carbon nanotubes by catalytic decomposition of methane显示文摘A new dual-composition catalyst based on Ni-Mo/MgO with high efficiency of producing carbon nanotubes (CNTs) from methane was reported recently. In the present article, with this type of catalyst, the impact of such experimental parameters as reaction temperature, reaction time, concentration of H2, ?ow rate ratio of CH4 to H2 on yield and graphitization were investigated, leading to the following optimal growth conditions: reaction time 60 min, reaction temperature 900 ?C, CH4:H2 about 100:20 mL/min, under which high-yield multi-walled CNTs bundles were synthesized. Raman measurement indicated that the as-synthesized product was well-graphitized, and the purity was estimated over 95% by TG-DSC analysis. In terms of the above results, an explanation of high-efficiency formation of CNTs bundles and the co-catalysis mechanism of Ni-Mo/MgO were suggested. | Shuanglin Zhan Yajun Tian Yanbin Cui Hao Wu Yonggang Wang Shufeng Ye Yunfa Chen | 2007 | China Particuology2007，5，3： | 1 |
| 18 | Direct electrochemical preparation of CeNi 5 and La x Ce 1? x Ni 5 alloys from mixed oxides by SOM process显示文摘 | Bingjian Zhao Xionggang Lu Qingdong Zhong Chonghe Li Shuanglin Chen | 2010 | Electrochimica Acta2010，，8： | 1 |
| 19 | Quantifying the Response Strength of the Southern Stratospheric Polar Vortex to Indian Ocean Warming in Austral Summer显示文摘A previous multiple-AGCM study suggested that Indian Ocean Warming(IOW) tends to warm and weaken the southern polar vortex. Such an impact is robust because of a qualitative consistency among the five AGCMs used. However, a significant difference exists in the modeled strengths, particularly in the stratosphere, with those in three of the AGCMs(CCM3, CAM3, and GFS) being four to five times as strong as those in the two other models(GFDL AM2, ECHAM5). As to which case reflects reality is an important issue not only for quantifying the role of tropical ocean warming in the recent modest recovery of the ozone hole over the Antarctic, but also for projecting its future trend. This issue is addressed in the present study through comparing the models' climatological mean states and intrinsic variability, particularly those influencing tropospheric signals to propagate upward and reach the stratosphere. The results suggest that differences in intrinsic variability of model atmospheres provide implications for the difference. Based on a comparison with observations, it is speculated that the impact in the real world may be closer to the modest one simulated by GFDL AM2 and ECHAM5, rather than the strong one simulated by the three other models(CCM3, CAM3 and GFS). In particular, IOW during the past 50 years may have dynamically induced a 1.0℃ warming in the polar lower stratosphere(~100 hPa), which canceled a fraction of radiative cooling due to ozone depletion. | LI Shuanglin CHEN Xiaoting | 2014 | Advances in Atmospheric Sciences2014，31，2： | 0 |
| 20 | Calculation and application of liquidus projection显示文摘Liquidus projection usually refers to a two-dimensional projection of ternary liquidus univariant lines at constant pressure. The algorithms used in Pandat for the calculation of liquidus projection with isothermal lines and invariant reac- tion equations in a ternary system are presented. These algorithms have been extended to multicomponent liquidus projec- tions and have also been implemented in Pandat. Some examples on ternary and quaternary liquidus projections are pre- sented. | CHEN Shuanglin CAO Weisheng YANG Ying ZHANG Fan WU Kaisheng DU Yong YAustin Chang | 2006 | Rare Metals2006，25，5： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员