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| 1 | Contributions of phosphatase and microbial activity to internal phosphorus loading and their relation to lake eutrophication显示文摘Phosphatase may accelerate the process of lake eutrophication through improving phosphorus bioavailability. This mechanism was studied in three Chinese eutrophic shallow lakes (Lake Taihu, Lake Longyang and Lake Lianhua). Phosphatase activity was related to the concentration of soluble reactive phosphorus (SRP) and chlorophyll a. Stability of dissolved phosphatase in reverse micelles may be attributed to molecular size, conformation and active residues of the enzyme.At the site with Microcystis bloomed in Lake Taihu, dissolved phosphatase activity was higher and more stable in micelles, SRP concentrations were lower in interstitial water, the contents of different forms of phosphorus and the amounts of aerobic bacteria were lower while respiration efficiency was higher in sediments. Phosphobacteria, both inorganic and organic and other microorganisms were abundant in surface water but rare in sediments. Therefore, internal phosphorus may substantially flux into water column by enzymatic hydrolysis and anaerobic release, together with mobility of bacteria,thereby initiating the bloom. In short, biological mechanism may act in concert with physical and chemical factors to drive the internal phosphorus release and accelerate lake eutrophication. | SONG Chunlei, CAO Xiuyun, LI Jianqiu, LI Qingman, CHEN Guoyuan & ZHOU Yiyong Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, China Graduate School of the Chinese Academy of Sciences, Beijing 100039, China | 2006 | Science China Earth Sciences2006，49，z1： | 5 |
| 2 | Cloning and expression of the Chinese wheat mosaic virus RNA2 coat protein read-through and 19 ku cysteine-rich domains and localization of these proteins显示文摘The 5’-terminal (RTn) and 3’-terminal (RTc) halves of the coat protein readthrough domain and the 19 ku cysteine-rich protein of Chinese wheat mosaic virus (CWMV) were amplified by RT-PCR, cloned and expressed in E. coll. Antisera and monoclonal antibodies against these proteins were prepared by immunising these purified proteins to mice. Detection of RTn, RTc and 19 ku proteins in CWMV infected wheat sap and leaf tissue indicated that the RTn and RTc proteins were distributed on the surface of virus particles whereas the 19 ku protein was in the cytoplasm of the infected wheat cells. | XU Lei CHEN Jianping YE Rong ZHAO Xiuyun YU Shanqing | 2002 | Chinese Science Bulletin2002，47，12： | 4 |
| 3 | Hydrogen production from ammonia decomposition over Ni/CeO_(2) catalyst:Effect of CeO_(2) morphology显示文摘Ammonia(NH_(3)) decomposition to release CO_x-free hydrogen(H_(2)) over non-noble catalysts has gained increasing attention.In this study,three nanostructured CeO_(2) with different morphologies,viz.rod(R).sphere(Sph),and spindle(Spi),were fabricated and served as supports for Ni/CeO_(2) catalyst.The CeO_(2)supports are different in particle sizes,specific surface area and porosity,resulting in the formation of Ni nanoparticles with distinguished sizes and dispersions.The surface properties of the Ni/CeO_(2) catalysts are not only distinct but also influential,affecting the adsorption and desorption of NH_(3),N_(2),and/or H_(2)molecules.The Ni/CeO_(2)-R catalyst shows superior catalytic activity compared to the other two,owing to its smaller Ni crystallite size and larger BET surface area.The most abundant strong basic sites are observed for Ni/CeO_(2)-Spi catalyst based on its exposed CeO_(2)(110) planes,which facilitates the donation of electrons to the Ni particles,benefiting the associative desorption of N atoms.Thus,Ni/CeO_(2)-Spi shows higher catalytic activity than Ni/CeO_(2)-Sph,despite their almost identical Ni crystallite sizes. | Chongqi Chen Xiaoshuang Fan Chen Zhou Li Lin Yu Luo Chaktong Au Guohui Cai Xiuyun Wang Lilong Jiang | 2023 | Journal of Rare Earths2023，41，7： | 3 |
| 4 | Studies on the edwardsiellosis and characterization of pathogenic bacteria from diseased flounder (Paralichthys olivaceus L.) and turbot (Scophthalmus maximus L.)显示文摘Edwardsiellosis of flounder and turbot occurring in different mariculture farms during 2001~2004 was examined, including the conditions of disease occurrence, clinical signs and pathological changes. The results showed that all diseased fishes expressed bacterial septicaemia. A total of 148 strains were identified using a combination of traditional physiological and biochemical tests and partial 16S rRNA gene analysis. In addition, the mole fraction G+C ratio of the DNA of representative strain of isolates and serum homology were detected, and pathogenicity tests of isolates were conducted by experimental infection. The results revealed that 148 strains were identified as E.tarda of genus Edwardsiella, all the isolates are of serologic similarity, and have strong pathogenicity to flounder and turbot. | FANG Hai ZHANG Xiaojun CHEN Cuizhen JIN Xiaomin WANG Xiuyun | 2006 | Acta Oceanologica Sinica2006，25，3： | 3 |
| 5 | Methyltransferase like 13 mediates the translation of Snail in head and neck squamous cell carcinoma显示文摘Methyltransferase like 13(METTL13),a kind of methyltransferase,is implicated in protein binding and synthesis.The upregulation of METTL13 has been reported in a variety of tumors.However,little was known about its potential function in head and neck squamous cell carcinoma(HNSCC)so far.In this study,we found that METTL13 was significantly upregulated in HNSCC at both mRNA and protein level.Increased METTL13 was negatively associated with clinical prognosis.And METTL13 markedly affected HNSCC cellular phenotypes in vivo and vitro.Further mechanism study revealed that METTL13 could regulate EMT signaling pathway by mediating enhancing translation efficiency of Snail,the key transcription factor in EMT,hence regulating the progression of EMT.Furthermore,Snail was verified to mediate METTL13-induced HNSCC cell malignant phenotypes.Altogether,our study had revealed the oncogenic role of METTL13 in HNSCC,and provided a potential therapeutic strategy. | Xiaochen Wang Kang Li Yuehan Wan Fangfang Chen Maosheng Cheng Gan Xiong Ganping Wang Shuang Chen Zhi Chen Jianwen Chen Xiuyun Xu Cheng Wang Liang Peng Demeng Chen | 2021 | International Journal of Oral Science2021，13，3： | 3 |
| 6 | Injectable melatonin-loaded carboxymethyl chitosan(CMCS)-based hydrogel accelerates wound healing by reducing inflammation and promoting angiogenesis and collagen deposition显示文摘Carboxymethyl chitosan(CMCS)-based hydrogels have antibacterial activity,and have shown the abilities of preventing wound infection,promoting cell proliferation,accelerating collagen deposition,and stimulating hyaluronic acid formation during wound healing.As a hormone produced by the pineal gland in humans and animals,melatonin promotes skin wound healing by regulating the release of inflammatory mediators and accelerating the proliferation and migration of cells,angiogenesis,and collagen deposition.However,the combined effects of CMCS and melatonin on wound healing remain unclear.Injectable CMCS-based hydrogels containing melatonin were prepared,and their healing effects were evaluated using a full-thickness cutaneous wound model in rats.Compared with the control and the hydrogel with no melatonin groups,the melatonin-loaded hydrogel significantly increased the percentage of wound closure,promoted the proliferation of granulation tissue and re-epithelialization,and accelerated collagen deposition.Additionally,the melatonin-loaded hydrogel promoted angiogenesis and vascular endothelial growth factor receptor protein expression and increased the expression of cyclooxygenase-2 and inducible nitric oxide synthase.The melatonin-loaded hydrogel also markedly increased the expression of collagen III,α-smooth muscle actin,and transforming growth factor-β1 proteins and reduced collagen I expression.These results suggest that the melatonin-loaded hydrogel promoted granulation tissue formation and accelerated wound healing by reducing inflammation and promoting angiogenesis and collagen deposition. | Kai Chen Changci Tong Jinge Yang Peifang Cong Ying Liu Xiuyun Shi Xu Liu Jun Zhang Rufei Zou Keshen Xiao Yuyang Ni Lei Xu Mingxiao Hou Hongxu Jin Yunen Liu | 2021 | Journal of Materials Science & Technology2021，，4： | 2 |
| 7 | Electrical Properties of Expanded Graphite Intercalation Compounds显示文摘The intercalation compounds of CuCl2 were synthesized with expanded graphite, whose magni-tude of the electrical conductivity is about 103S.cm1. Their electrical conductivity is 3-6 times as high as that of the expanded graphite, and about 10 times as high as that of GIC made of the non-expanded graphite. The microanalysis results of chemical compounds by X-ray energy spectrum scanning of TEM testified that the atomic ratio of chloride and cupric is nonstoichoi-metric. The multivalence and exchange of electrovalence of the cupric ion was confirmed by the XPS-ESCA. Vacancy of chlorine anion increases the concentration of charge carrier. The special stage structure, made of graphite and chloride, produces a weak chemical bond belt and provides a carrier space in the direction of GIC layer. These factors develop the electrical properties. | Xiuyun CHUAN Department of Geology, Peking University, Beijing 100871, China Daizhang CHEN and Xunruo ZHOU Department of Materials Science, China University of Geosciences, Beijing 100083, China E-mail: cxyljhcj@pku.edu.cn | 2001 | Journal of Materials Science & Technology2001，17，3： | 2 |
| 8 | Phosphorus fractions and alkaline phosphatase activity in sediments of a large eutrophic Chinese lake (Lake Taihu)显示文摘 | Yiyong Zhou Chunlei Song Xiuyun Cao Jianqiu Li Guoyuan Chen Zhuoying Xia Pinghong Jiang | 2008 | Hydrobiologia2008，，1： | 1 |
| 9 | Subdivision Surface-Based Isogeometric Boundary Element Method for Steady Heat Conduction Problems with Variable Coefficient显示文摘The present work couples isogeometric analysis(IGA)and boundary element methods(BEM)for three dimensional steady heat conduction problems with variable coefficients.The Computer-Aided Design(CAD)geometries are built by subdivision surfaces,and meantime the basis functions of subdivision surfaces are employed to discretize the boundary integral equations for heat conduction analysis.Moreover,the radial integration method is adopted to transform the additional domain integrals caused by variable coefficients to the boundary integrals.Several numerical examples are provided to demonstrate the correctness and advantages of the proposed algorithm in the integration of CAD and numerical analysis. | Xiuyun Chen Xiaomeng Yin Kunpeng Li Ruhui Cheng Yanming Xu Wei Zhang | 2021 | Computer Modeling in Engineering & Sciences2021，，10： | 1 |
| 10 | The Strategy of Combined Ischemia Preconditioning and Salvianolic Acid-B Pretreatment to Prevent Hepatic Ischemia-Reperfusion Injury in Rats显示文摘 | Rui Kong Yue Gao Bei Sun Hua Chen Gang Wang Xiuyun Wang Hong Zhu Shangha Pan Dongbo Xue Hongchi Jiang | 2009 | Digestive Diseases and Sciences2009，，12： | 1 |
| 11 | Simultaneous improvement in cold tolerance and yield of temperate japonica rice ( O ryza sativa L .) by introgression breeding显示文摘 | Lijun Meng Xiuyun Lin Jinming Wang Kai Chen Yanru Cui Jianlong Xu Zhikang Li | 2013 | Plant Breed2013，，6： | 1 |
| 12 | Morphology ecology and contaminant removal efficiency of eight wetland plants with di- ffering root systems 显示文摘 | Cheng Xiuyun Chen Wenyin Gu Binhe | 2009 | Hydrobiologia2009，623，1： | 1 |
| 13 | Phosphorus fractions and alkaline phosphatase activity in sediments of a large eutrophic Chinese lake (Lake Taihu)显示文摘 | Yiyong Zhou Chunlei Song Xiuyun Cao Jianqiu Li Guoyuan Chen Zhuoying Xia Pinghong Jiang | 2008 | Hydrobiologia2008，，1： | 1 |
| 14 | Novel air-cooling bainitic steels显示文摘 | FANG Hongsheng ZHENG Yankang CHEN Xiuyun | 1988 | Journal of Metals1988，40，3： | 1 |
| 15 | Novel air-cooling bainitic steels显示文摘 | Fang Hongsheng Zheng Yankang Chen Xiuyun | 1988 | Journal of Metals1988，40，3： | 1 |
| 16 | Homogeneous distributed natural pyrite-derived composite induced by modified graphite as high-performance lithium-ion batteries anode显示文摘Natural minerals-based energy materials have attracted enormous attention because of the advantages of good materials consistency,high production,environmental friendliness,and low cost.The uniform distribution of grains can effectively inhibit the aggregation of active materials,improving lithium storage performance.In this work,natural graphite is modified by polyvinylpyrrolidone to obtain modified graphite with reduced size and better dispersion.Natural pyrite composite polyvinylpyrrolidone-modified graphite(pyrite/PG)material with uniform particle distribution is obtained by the ball milling process.The subsequent calcination process converts pyrite/PG into Fe_(1-x)Scompounded with polyvinylpyrrolidone-modified graphite(Fe_(1-x)S/PG).The homogeneous grain distributions of active material can facilitate the faster transfer of electrons and promote the efficient utilization of active materials.The as-prepared Fe_(1-x)S/PG electrode exhibits a remarkably reversible specific capacity of 613.0 mAh·g^(-1)at 0.2 A·g^(-1)after 80 cycles and an excellent rate capability of 523.0 mAh·g^(-1)at 5 A·g^(-1).Even at a higher current density of 10 A·g^(-1),it can deliver a specific capacity of 348.0 mAh·g^(-1).Moreover,the dominant pseudocapacitance in redox reactions accounts for the impressive rate and cycling stability.This work provides a low-cost and facile method to fabricate natural mineral-based anode materials and apprise readers about the impact of uniform particle distribution on lithium storage performance. | Juan Yu Yinbo Wei Bicheng Meng Jiaxin Peng Kai Yang Tianxing Chen Naixing Yang Xiuyun Chuan | 2023 | International Journal of Minerals,Metallurgy and Materials2023，30，7： | 0 |
| 17 | Single-cell transcriptomic analysis uncovers the origin and intratumoral heterogeneity of parotid pleomorphic adenoma显示文摘Pleomorphic adenoma(PA)is the most common benign tumour in the salivary gland and has high morphological complexity.However,the origin and intratumoral heterogeneity of PA are largely unknown.Here,we constructed a comprehensive atlas of PA at single-cell resolution and showed that PA exhibited five tumour subpopulations,three recapitulating the epithelial states of the normal parotid gland,and two PA-specific epithelial cell(PASE)populations unique to tumours.Then,six subgroups of PASE cells were identified,which varied in epithelium,bone,immune,metabolism,stemness and cell cycle signatures.Moreover,we revealed that CD36+myoepithelial cells were the tumour-initiating cells(TICs)in PA,and were dominated by the PI3K-AKT pathway.Targeting the PI3K-AKT pathway significantly inhibited CD36+myoepithelial cell-derived tumour spheres and the growth of PA organoids.Our results provide new insights into the diversity and origin of PA,offering an important clinical implication for targeting the PI3K-AKT signalling pathway in PA treatment. | Xiuyun Xu Jiaxiang Xie Rongsong Ling Shengqi Ouyang Gan Xiong Yanwen Lu Bokai Yun Ming Zhang Wenjin Wang Xiqiang Liu Demeng Chen Cheng Wang | 2023 | International Journal of Oral Science2023，15，3： | 0 |
| 18 | Facile Synthesis and High-Value Utilization of Ammonia显示文摘Ammonia is a key component in fertilizer and the carbon-free hydrogen carrier.Catalytic ammonia synthesis and utilization have played a central role in the development of chemical engineering.The industrial production of ammonia remains dependent on the energy-and carbon-intensive Haber-Bosch process.A major effort has been devoted to developing robust and efficient catalysts,as well as alternative benign processes.Herein,we detail our endeavors that develop the ammonia synthesis and decomposition catalysts,and utilize the ammonia energy.We firstly discuss the catalysts for ammonia synthesis via dissociative and associative process,and the regulation of catalysts'properties.Then,we review the burgeoning electrocata-lytic nitrogen reduction process,focusing on the enhanced catalytic performances by the regulation of the catalysts and the electrode.Additionally,we provide a novel high-value utilization of ammonia to achieve the'zero-carbon'circular economy.The promising catalysts,reactors,and ammonia energy systems have been discussed in detail.We end this Account that offers future research directions and prospects of ammonia. | Yu Luo Shijing Liang Xiuyun Wang Bingyu Lin Chongqi Chen Lilong Jiang | 2022 | Chinese Journal of Chemistry2022，40，8： | 0 |
| 19 | Sox9^(+) cells are required for salivary gland regeneration after radiation damage via the Wnt/β-catenin pathway显示文摘Radiotherapy for head and neck cancer can cause serious side effects, including severe damage to the salivary glands, resulting in symptoms such as xerostomia, dental caries, and oral infection. Because of the lack of long-term treatment for the symptoms of xerostomia, current research has focused on finding endogenous stem cells that can differentiate into various cell lineages to replace lost tissues and restore functions. Here, we report that Sox9^(+)cells can differentiate into various salivary epithelial cell lineages under homeostatic conditions. After ablating Sox9^(+) cells, the salivary glands of irradiated mice showed more severe phenotypes and the reduced proliferative capacity. Analysis of online single-cell RNAsequencing data reveals the enrichment of the Wnt/β-catenin pathway in the Sox9^(+) cell population.Furthermore, treatment with a Wnt/β-catenin inhibitor in irradiated mice inhibits the regenerative capability of Sox9^(+) cells. Finally, we show that Sox9^(+) cells are capable of forming organoids in vitro and that transplanting these organoids into salivary glands after radiation partially restored salivary gland functions.These results suggest that regenerative therapy targeting Sox9^(+) cells is a promising approach to treat radiation-induced salivary gland injury. | Xiuyun Xu Gan Xiong Ming Zhang Jiaxiang Xie Shuang Chen Kang Li Jingting Li Yong Bao Cheng Wang Demeng Chen | 2022 | Journal of Genetics and Genomics2022，49，3： | 0 |
| 20 | Heterometallic cluster-based organic frameworks as highly active electrocatalysts for oxygen reduction and oxygen evolution reaction:a density functional theory study显示文摘Recently,metal–organic frameworks are one of the potential catalytic materials for electrocatalytic applications.The oxygen reduction reaction and oxygen evolution reaction catalytic activities of heterometallic cluster-based organic frameworks are investigated using density functional theory.Firstly,the catalytic activities of heterometallic clusters are investigated.Among all heterometallic clusters,Fe_(2)Mn–Mn has a minimum overpotential of 0.35 V for oxygen reduction reaction,and Fe_(2)Co–Co possesses the smallest overpotential of 0.32 V for oxygen evolution reaction,respectively 100 and 50 mV lower than those of Pt(111)and RuO_(2)(110)catalysts.The analysis of the potential gap of Fe_(2)M clusters indicates that Fe_(2)Mn,Fe_(2)Co,and Fe_(2)Ni clusters possess good bifunctional catalytic activity.Additionally,the catalytic activity of Fe_(2)Mn and Fe_(2)Co connected through 3,3′,5,5′-azobenzenetetracarboxylate linker to form Fe_(2)M–PCN–Fe_(2)M is explored.Compared with Fe_(2)Mn–PCN–Fe_(2)Mn,Fe_(2)Co–PCN–Fe_(2)Co,and isolated Fe_(2)M clusters,the mixed-metal Fe_(2)Co–PCN–Fe_(2)Mn possesses excellent bifunctional catalytic activity,and the values of potential gap on the Mn and Co sites of Fe_(2)Co–PCN–Fe_(2)Mn are 0.69 and 0.70 V,respectively.Furthermore,the analysis of the electron structure indicates that constructing a mixed-metal cluster can efficiently enhance the electronic properties of the catalyst.In conclusion,the mixed-metal cluster strategy provides a new approach to further design and synthesize high-efficiency bifunctional electrocatalysts. | Xin Chen Liang Luo Shihong Huang Xingbo Ge Xiuyun Zhao | 2023 | Frontiers of Chemical Science and Engineering2023，17，5： | 0 |
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