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9篇 您的检索式:作者名="Chengda He"
    题名 作者 年代 出处 被引量
1Combined effects of volume ratio and nitrate recycling ratio on nutrient removal,sludge characteristic and microbial evolution for DPR optimization显示文摘The optimization of volume ratio(V_(An)/V_(A)/V_(0))and nitrate recycling ratio(R)in a two-sludge denitrifying phosphorus removal(DPR)process of Anaerobic Anoxic Oxic-Moving Bed Biofilm Reactor(A^(2)/O-MBBR)was investigated.The results showed that prolonged anaerobic retention time(HRT An:1.25→3.75 hr)exerted favorable effect on chemical oxygen demand(COD)removal(57.26%→73.54%),poly-β-hydroxyalkanoates(PHA)synthesis(105.70→138.12 mg COD/L)and PO_(4)^(3-)release(22.3→38.9 mg/L).However,anoxic retention time(HRT A)and R exhibited positive correlation with PHA utilization(43.87%-81.34%)and denitrifying phosphorus removal(DPR)potential(NO_(3)-/PO^(3-)_(4):0.57-1.34 mg/mg),leading to dramatical TN removal variations from 68.86%to 81.28%.Under the V An/V A/V O ratio of 2:6:0,sludge loss deteriorated nutrient removals but the sludge bioactivity quickly recovered when the oxic zone was recovered.The sludge characteristic and microstructure gradually transformed under the dissolved oxygen(DO)control(1.0-1.5→1.5-2.0 mg/L),in terms of sludge volume index(SVI:194→57 m L/g VSS),median-particle-size(D 50:99.6→300.5μm),extracellular polymeric substances(EPS)(105.62→226.18 mg/g VSS)and proteins/polysaccharides(PN/PS)ratio(1.52→3.46).Fluorescence in situ hybridization(FISH)results showed that phosphorus accumulation organisms(PAOs)(mainly Cluster I of Accumulibacter,contribution ratio:91.79%-94.10%)dominated the superior DPR performance,while glycogen accumulating organisms(GAOs)(mainly Competibacter,contribution ratio:82.61%-86.89%)was responsible for deteriorative TN and PO_(4)^(3-)removals.The optimal HRT A and R assembled around 5-6.5 hr and 300%-400%based on the PHA utilization and DRP performance,and the oxic zones also contributed to PO_(4)^(3-)removal although it showed low dependence on DO concentration and oxic retention time(HRT_(0)).Miao Zhang Jing Gao Yajun Fan Xiaoge Wu Jun Wu Chengda He 2021Journal of Environmental Sciences2021,33,6:6
2An antiretroviral regimen containing 6 months of stavudine followed by long-term zidovudine for first-fine HIV therapy is optimal in resource-limited settings: a prospective, multicenter study in China显示文摘Li Taisheng Guo Fuping Li Yijia Zhang Chengda Han Yang Lye Wei He Yun Lu Hongzhou Xie Jing Huang Aiqiong Li Yanling Tang Xiaoping Wang Hui Zhang Tong Gao Guiju Lei Junkang Zhang Xiaoying Wu Xinhua Sun Yongtao Bai Jinsong Luo Ling Wang Huanlmg 2014Chinese Medical Journal2014,,1:6
3Corrosion analysis, and use of an inhibitor in oil wells显示文摘Jiandong Li Chengda Wang Jie Liu Li Liu Zhifu Yin Yongqiang Zhang Hui Li Fei He 2014Research on Chemical Intermediates2014,,2:1
4Modeling of the submerged membrane bioreaetor fouling by the combined pore constriction, pore blockage and cake formation mechanisms显示文摘Wu Jun He Chengda Jiang Xinyue 2011Desalination2011,279,:1
5Surface modification of pure titanium treated with B 4 C at high temperature显示文摘Lijian He Xiaonong Zhang Chengda Tong 2004Surface & Coatings Technology2004,,9:1
6Modeling membrane fouling in a submerged membrane bioreactor by considering the role of solid,colloidal and soluble components 显示文摘Wu Jun He Chengda Zhang Yaping 2012Journal of Membrane Science2012,397,:1
7Surface modifica- tion of pure titanium treated with B,C at high temperature 显示文摘He Lijian Zhang Xiaonong Tong Chengda 2006Surface & Coatings Technology2006,,200:1
8The effect of settlement on wastewater carbon source availability based on respirometric and granulometric analysis 显示文摘Wu Jun He Chengda 2012Chemical Engineering Journal2012,,5:1
9A boronic acid conjugation integrates antitumor drugs into albumin-binding prodrugs-based nanoparticles with robust efficiency for cancer therapy显示文摘Despite great therapeutic effect of Abraxane®,complex preparation technology and unfavorable pharmacokinetics still restricted the clinical application of albumin-based paclitaxel(PTX)nanoparticles(NPs).Herein,we reported that an albumin-binding prodrug,phenylboronic acid-conjugated PTX(P-PTX),can form the uniform NPs with the diameters around 100 nm with the help of albumin via simple one-step nano-precipitation method.The albumin-based nanomedicines were stabilized by the integration of a single boronic acid with PTX due to the increased affinity based on multiple intermolecular interactions.We found that albumin-based P-PTX NPs exhibited superior colloidal stability over albumin-based PTX NPs through one-step nanoprecipitation approach,achieving longer in vivo circulation time and higher concentration in tumor than those of the marketed Abraxane®.Furthermore,the albumin-based P-PTX NPs with great stability and enhanced intratumoral enrichment,increased the maximum tolerated dose of PTX,remarkably suppressed the growth of breast tumor and lung metastasis,prolonged survival of melanoma tumors-bearing mice.Such a convenient and effective system gains an insight into the impact of phenylboronic acid group on the albumin-based PTX NPs,provides potent strategy for the rational design of albumin-based antitumor nanomedicines.Weiyue Ban Qiuhua Luo Chengda Yan Xiaoying Fan Guorui Zhu Maosheng Cheng Zhonggui He Mengchi Sun Jin Sun 2023Nano Research2023,16,5:0
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