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3篇 您的检索式:作者名="Chengyan Jin"
    题名 作者 年代 出处 被引量
1Guards at the gate: physiological and pathological roles of tissue-resident innate lymphoid cells in the lung显示文摘Hang Cheng Chengyan Jin Jing Wu Shan Zhu Yong-Jun Liu Jingtao Chen 2017Protein & Cell2017,8,12:3
2Recommendation for Cardiac Magnetic Resonance Imaging-Based Phenotypic Study:Imaging Part显示文摘Cardiac magnetic resonance(CMR)imaging provides important biomarkers for the early diagnosis of many cardiovascular diseases and has been reported to reveal phenome-wide associations of cardiac/aortic structure and functionality in popula-tion studies.Nevertheless,due to the complexity of operation and variations among manufactural vendors,magnetic field strengths,coils,sequences,scan parameters,and image analysis approaches,CMR is rarely used in large cohort studies.Existing guidelines mainly focused on the diagnosis of cardiovascular diseases,which did not aim to basic research.The purpose of this study was to propose a recommendation for CMR based phenotype measurements for cohort study.We classify the imaging sequences of CMR into three categories according to the importance and universality of correspond-ing measurable phenotypes.The acquisition time and repeatability of the phenotypic measurement were also taken into consideration during the categorization.Unlike other guidelines,this recommendation focused on quantitative measurement of large amount of phenotypes from CMR.Chengyan Wang Yan Li Jun Lv Jianhua Jin Xumei Hu Xutong Kuang Weibo Chen He Wang 2021Phenomics2021,1,4:1
3Reciprocal costimulatory molecules control the activation of mucosal type 3 innate lymphoid cells during engagement with B cells显示文摘Innate lymphoid cells(ILCs)are the counterpart of T helper cells in the innate immune system and share multiple phenotypes with T helper cells.Inducible T-cell costimulator(ICOS)is recognized on T cells and participates in T-cell activation and T and B-cell engagement in lymphoid tissues.However,the role of ICOS in ILC3s and ILC3-involved interactions with the immune microenvironment remains unclear.Here,we found that ICOS expression on human ILC3s was correlated with the activated state of ILC3s.ICOS costimulation enhanced the survival,proliferation,and capacity of ILC3s to produce cytokines(IL-22,IL-17A,IFN-γ,TNF,and GM-CSF).Via synergistic effects of ICOS and CD40 signaling,B cells promoted ILC3 functions,and ILC3-induced T-cellindependent B-cell IgA and IgM secretion primarily required CD40 signaling.Hence,ICOS is essential for the nonredundant role of ILC3s and their interaction with adjacent B cells.Xinping Lv Shan Zhu Jing Wu Jinfeng Shi Qiuyu Wei Tete Li Ning Yang Chunyan Liu Lingli Qi Guoxia Zang Hang Cheng Zhiguang Yang Chengyan Jin Yusheng Wang Jiuwei Cui Hideki Ueno Yong-Jun Liu Jingtao Chen 2023Cellular & Molecular Immunology2023,20,7:0
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