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| 1 | Characterization of acid-and pepsin-soluble collagens from spines and skulls of skipjack tuna(Katsuwonus pelamis)显示文摘Acid-soluble collagen(ASC) and pepsin-soluble collagen(PSC) from the spine(ASC-SP and PSC-SP) and skull(ASC-SK and PSC-SK) of the skipjack tuna, Katsuwonus pelamis, were successfully isolated and characterized. The yields of ASC-SP, PSC-SP, ASC-SK and PSC-SK were(2.47 ± 0.39)%,(5.62 ± 0.82)%,(3.57 ± 0.40)%, and(6.71 ± 0.81)%, respectively, on the basis of dry weight. The four collagens contained Gly(330.2-339.1 residues/1 000 residues) as the major amino acid, and their imino acid contents were between 168.8 and 178.2 residues/1 000 residues. Amino acid composition, SDS-PAGE, and FTIR investigations confirmed that ASC-SP and ASC-SK were mainly composed of type I collagen, and had higher contents of high-molecular weight cross-links than those of PSC-SK and PSC-SP. The FTIR investigation also certified all the collagens had triple helical structure. The denaturation temperatures of ASC-SK, PSC-SK, ASC-SP, and PSC-SP were 17.8, 16.6, 17.6, and 16.5 °C, respectively. All isolated collagens were soluble at acidic pH(1-5) and lost their solubilities when the NaCl concentration was above 2%(W/V). The isolated collagens from the spines and skulls of skipjack tuna could serve as an alternative source of collagens for further application in food, cosmetic, biomedical, and pharmaceutical industries. | YU Di CHI Chang-Feng WANG Bin DING Guo-Fang LI Zhong-Rui | 2014 | Chinese Journal of Natural Medicines2014，12，9： | 14 |
| 2 | Overexpression of SIRT3 disrupts mitochondrial proteostasis and cell cycle progression显示文摘 | Xiaofei Wang Haiping Tang Yuling Chen Binghuan Chi Shiyu Wang Yang Lv Di WU Renshan Ge Haiteng Deng | 2016 | Protein & Cell2016，7，4： | 3 |
| 3 | Priming of NLRP3 inflammasome activation by Msn kinase MINK1 in macrophages显示文摘The nucleotide-binding domain,leucine-rich-repeat containing family,pyrin domain-containing 3(NLRP3)inflammasome is essential in inflammation and inflammatory disorders.Phosphorylation at various sites on NLRP3 differentially regulates inflammasome activation.The Ser725 phosphorylation site on NLRP3 is depicted in multiple inflammasome activation scenarios,but the importance and regulation of this site has not been clarified.The present study revealed that the phosphorylation of Ser725 was an essential step for the priming of the NLRP3 inflammasome in macrophages.We also showed that Ser725 was directly phosphorylated by misshapen(Msn)/NIK-related kinase 1(MINK1),depending on the direct interaction between MINK1 and the NLRP3 LRR domain.MINK1 deficiency reduced NLRP3 activation and suppressed inflammatory responses in mouse models of acute sepsis and peritonitis.Reactive oxygen species(ROS)upregulated the kinase activity of MINK1 and subsequently promoted inflammasome priming via NLRP3 Ser725 phosphorylation.Eliminating ROS suppressed NLRP3 activation and reduced sepsis and peritonitis symptoms in a MINK1-dependent manner.Altogether,our study reveals a direct regulation of the NLRP3 inflammasome by Msn family kinase MINK1 and suggests that modulation of MINK1 activity is a potential intervention strategy for inflammasomerelated diseases. | Kaixiang Zhu Xuexiao Jin Zhexu Chi Sheng Chen Songquan Wu Richard D.Sloan Xuai Lin Dante Neculai Di Wang Hu Hu Linrong Lu | 2021 | Cellular & Molecular Immunology2021，18，10： | 2 |
| 4 | 有机污染物和碳纳米颗粒:吸附机理及影响因素(英文)显示文摘研究目的:碳纳米颗粒由于其独特的优良性能被广泛应用,从而不可避免地进入环境。进入环境的碳纳米颗粒与有机污染物有很强的相互作用,并且碳纳米颗粒对有机污染物的吸附可能会影响污染物的环境风险和迁移。因此,本研究总结了目前有机污染物在碳纳米颗粒上吸附的研究进展,为有机污染物及碳纳米颗粒的环境行为研究及风险评价提供重要信息。重要结论:有机污染物和碳纳米颗粒的主要相互作用有憎水性、静电、氢键和π-π作用,这些作用及它们的强度受碳纳米颗粒的表面性质、形态及有机污染物的分子大小、结构和官能团等影响。不同的吸附机理可能同时控制有机物在碳纳米颗粒上的吸附过程,而且在不同的环境条件下吸附控制机理不同。区分吸附控制机理和影响因素的研究对预测有机污染物和碳纳米颗粒的环境行为和风险非常重要。 | Hong-bo PENG Di ZHANG Hao LI Chi WANG Bo PAN | 2014 | Journal of Zhejiang University-Science A(Applied Physics & Engineering)2014，15，8： | 2 |
| 5 | Intraoperative mild hypothemaia does not increase the plasma concentration of stress hormones during neurosurgery 显示文摘 | Chi OZ Choi YK Lee DI | 2001 | Can J Anaesth2001，48，： | 1 |
| 6 | Formylchromone derivatives as a novel class of protein tyrosine phosphatase 1B inhibitors显示文摘 | Shim YS Kim KC Chi DI | 2003 | Bioorg Mel Chem Lett2003，313，15： | 1 |
| 7 | The effects of morphine on bloo-d- brain barrier disruption caused by intracarotid injection of hyperosmolar mannitol in rats显示文摘 | Chi OZ Lee DI Liu X | 2000 | Anesth Analg2000，90，3： | 1 |
| 8 | Complex behavior in switching power converter显示文摘 | Chi K Tse Mario Di Bernardo | 2002 | Proceeding of IEEE2002，90，5： | 1 |
| 9 | The OTSC clip for endoscopic organ closure in NOTES: Device and technique显示文摘 | Marc O. Schurr Alberto Arezzo Chi‐Nghia Ho Gunnar Anhoeck Gerhard Buess Nicola Di Lorenzo | 2008 | Minimally Invasive Therapy & Allied Technologies2008，，4： | 1 |
| 10 | Biomass-based N doped carbon as metal-free catalyst for selective oxidation of D-xylose into D-xylonic acid显示文摘Rational design and facile preparation of low-cost and efficient catalysts for the selective converting of biomass-derived monosaccharides into high value-added chemicals is highly demanded,yet challenging.Herein,we first demonstrate a N doped defect-rich carbon(NC-800-5)as metal-free catalyst for the selective oxidation of D-xylose into D-xylonic acid in alkaline aqueous solution at 100℃ for 30 min,with 57.4%yield.The doped graphitic N is found to be the active site and hydroxyl ion participating in the oxidation of D-xylose.Hydroxyl ion and D-xylose first adsorb on NC-800-5 surface,and the aldehyde group of D-xylose is catalyzed to form germinal diols ion.Then,C–H bond break to yield carboxylic group.Furthermore,NC-800-5 catalyst shows high stability in recycled test. | Zengyong Li Yiming Huang Xiao Chi Di Li Linxin Zhong Xuehui Li Chuanfu Liu Xinwen Peng | 2022 | Green Energy & Environment2022，7，6： | 1 |
| 11 | Development of Micro Wire Electrical Discharge Machining Platform and Its Applications 显示文摘 | Huang Ruining Di Shichun Chi Gunxin | 2005 | Transactions of Nonferrous Metals Society of Chi- na2005，15，： | 1 |
| 12 | Ultrasonic and electric discharge machining to deep and small hole on titanium alloy显示文摘 | Zhao Wansheng Wang Zhenlong Di Shichun Chi Guanxin Wei Hongyu | 2002 | Journal of Materials Processing Tech2002，，1： | 1 |
| 13 | Amyotrophic lateral sclerosis associated with pregnancy:report of four new cases and review of the literature显示文摘 | Chiò A Calvo A Di Vito N | | 0，，01： | 1 |
| 14 | 3,4-Dichlorotoluene Ammoxidation to 3,4-Dichlorobenzonitrile over VPO/SiO_2 Catalyst显示文摘Ammoxidation of 3,4\|dichlorotoluene(DCT) to prepare 3,4\|dichlorobenzonitrile (DCBN) over silica supported vanadium phosphorus oxide catalysts has been studied. On the VPO/SiO 2 catalyst, the influence of the reaction temperature, the molar ratio of air/DCT, the molar ratio of NH 3 /DCT in the feed gas and the space velocity ( v s) on the conversion, yield and selectivity was observed. The most appropriate reaction condition is: reaction T =673 K, n (DCT)∶ n (NH 3 )∶ n (air)=1∶7∶30 and v s=250 h -1 . At this optimum reaction condition, the conversion of DCT is 97.8%; the molar yield of DCBN is 67.4%. It was found that the addition of element phosphorus can improve the yield of DCBN compared with VO/SiO 2 catalyst. | Huang Chi, Xiao Di, Xu Hai\|xia, Zheng Qiong, Chen Yuan\|yin College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, Hubei. China | 2002 | Wuhan University Journal of Natural Sciences2002，7，3： | 1 |
| 15 | Ultrasonic and electric discharge machi ning to deep and small hole on titanium alloy显示文摘 | Di S C Chi G X | 2002 | Journal of Materials Processing Technology2002，120，13： | 1 |
| 16 | MicroRNA-146a negatively regulates PTGS2 expression induced by Helicobacter pylori in human gastric epithelial cells显示文摘 | Zhen Liu Di Wang Yongliang Hu Guoyong Zhou Chaohui Zhu Qi Yu Yingchun Chi Yingli Cao Chiyu Jia Quanming Zou | 2013 | Journal of Gastroenterology2013，，1： | 1 |
| 17 | Systematic investigation of millimeter-wave optic modulation performance in thin-film lithium niobate显示文摘Millimeter-wave(mmWave)band(30–300 GHz)is an emerging spectrum range for wireless communication,short-range radar,and sensor applications.mmWave-optic modulators that could efficiently convert mmWave signals into the optical domain are crucial components for long-haul transmission of mmWave signals through optical networks.At these ultrahigh frequencies,however,the modulation performances are highly sensitive to the transmission line loss as well as the velocity-and impedance-matching conditions,while precise measurements and modeling of these parameters are often non-trivial.Here we present a systematic investigation of the mmWave-optic modulation performances of thin-film lithium niobate modulators through theoretical modeling,electrical verifications,and electro-optic measurements at frequencies up to 325 GHz.Based on our experimentally verified model,we demonstrate thin-film lithium niobate mmWave-optic modulators with a measured 3-dB electro-optic bandwidth of 170 GHz and a 6-dB bandwidth of 295 GHz.The device also shows a low RF half-wave voltage of 7.3 V measured at an ultrahigh modulation frequency of 250 GHz.This work provides a comprehensive guideline for the design and characterization of mmWave-optic modulators and paves the way toward future integrated mmWave photonic systems for beyond-5G communication and radar applications. | YIWEN ZHANG LINBO SHAO JINGWEI YANG ZHAOXI CHEN KE ZHANG KAM-MAN SHUM DI ZHU CHI HOU CHAN MARKO LONČAR CHENG WANG | 2022 | Photonics Research2022，10，10： | 1 |
| 18 | Inhibitory effect of rebamipide on the neutrophil adherence stimulated by conditional media form helicobacter pylori-infected gastric epithelial cells显示文摘 | Chi Dae Kim Hyun Hee Kim Di Whan Hong | 1999 | The Journal of pharmacology and experimental therapeutics1999，288，： | 1 |
| 19 | Development of MWEDM platform and its applications显示文摘 | HUANG R N DI S C CHI G X | 2005 | Transactions of Nonferrous Metals Society of China2005，15，3： | 1 |
| 20 | Design of energy-controllable pulse显示文摘 | Chi G X Cao G H Di S C | 2008 | Key Engeering Materials2008，，： | 1 |
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