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| 1 | Kernel matrix learning with a general regularized risk functional criterion显示文摘Kernel-based methods work by embedding the data into a feature space and then searching linear hypothesis among the embedding data points. The performance is mostly affected by which kernel is used. A promising way is to learn the kernel from the data automatically. A general regularized risk functional (RRF) criterion for kernel matrix learning is proposed. Compared with the RRF criterion, general RRF criterion takes into account the geometric distributions of the embedding data points. It is proven that the distance between different geometric distributions can be estimated by their centroid distance in the reproducing kernel Hilbert space. Using this criterion for kernel matrix learning leads to a convex quadratically constrained quadratic programming (QCQP) problem. For several commonly used loss functions, their mathematical formulations are given. Experiment results on a collection of benchmark data sets demonstrate the effectiveness of the proposed method. | Chengqun Wang Jiming Chen Chonghai Hu Youxian Sun | 2010 | Journal of Systems Engineering and Electronics2010，21，1： | 3 |
| 2 | CRISPR/Cas9-mediated genome engineering of the ferret显示文摘 | Zhaohui Kou Qian Wu Xiaochen Kou Chonghai Yin Hong Wang Zhentao Zuo Yan Zhuo Antony Chen Shaorong Gao Xiaoqun Wang | 2015 | Cell Research2015，25，12： | 3 |
| 3 | SIGNIFICANCE OF LANGUAGE LEARNER’S ERRORS TO THE TEACHER显示文摘IntroductionThe attitudes towards foreign learners’ errors have changed remarkably from the 1960s to recentyears.In the eyes of behaviourists in the 1960s,errors were considered terrible.Teachers tried tostructure the classroom situation so as to make it ideally impossible for students to make errors.Sincethe evolution of Chomsky’s theory and modernism,teachers have begun to believe thatcommunication in the language is more important than a sterile perfection of form.and therefore,they have become more tolerant of students’ errors.Making errors has been recognised more andmore as inevitable and as an essential part of language learning. | Qi Chonghai Public Security University | 1996 | Chinese Journal of Applied Linguistics1996，19，1： | 2 |
| 4 | Developing hierarchical CdS/NiO hollow heterogeneous architectures for boosting photocatalytic hydrogen generation显示文摘The hierarchical binary CdS/NiO hollow heterogeneous architectures(HHAs)with p–n heterojunction are constructed by a facile microwave-assisted wet chemical process for high-efficient photocatalytic hydrogen evolution reaction(HER)from water.The as-designed CdS/NiO HHAs are composed of hexagonal n-type CdS nanoparticles with a size in the range of 20–40 nm attaching to cubic p-type NiO hollow microspheres(HMSs)which are aggregates of porous nanoplates with a thickness of about 20 nm.The photocatalytic water splitting over CdS/NiO HHAs is significantly increased under simulated solar irradiation,among which the most active sample of CdS/NiO-3(the mass ratio of CdS to NiO is 1:3)exhibits the fastest photocatalytic HER rate of 1.77 mmol∙g^(−1)∙h^(−1),being 16.2 times than that of pure CdS.The boosted photocatalytic HER could be attributed to the synergistic effect on the proportional p–n heterojunction with special hierarchical hollow and porous morphology,an enhancement of visible light absorption,and an improvement of photoinduced charge separation as well as the photo-stability given by the composite heterojunction.This work shows a viable strategy to design the heterojunction with special morphology for the efficient hydrogen generation by water splitting utilizing solar energy. | Chonghai Deng Fan Ye Tao Wang Xiaohui Ling Lulu Peng Hong Yu Kangzhe Ding Hanmei Hu Qiang Dong Huirong Le Yongsheng Han | 2022 | Nano Research2022，15，3： | 2 |
| 5 | Transcriptome dynamics of hippocampal neurogenesis in macaques across the lifespan and aged humans显示文摘Whether adult hippocampal neurogenesis(AHN)persists in adult and aged humans continues to be extensively debated.A major question is whether the markers identified in rodents are reliable enough to reveal new neurons and the neurogenic trajectory in primates.Here,to provide a better understanding of AHN in primates and to reveal more novel markers for distinct cell types,droplet-based single-nucleus RNA sequencing(snRNA-seq)is used to investigate the cellular heterogeneity and molecular characteristics of the hippocampi in macaques across the lifespan and in aged humans.All of the major cell types in the hippocampus and their expression profiles were identified.The dynamics of the neurogenic lineage was revealed and the diversity of astrocytes and microglia was delineated.In the neurogenic lineage,the regulatory continuum from adult neural stem cells(NSCs)to immature and mature granule cells was investigated.A group of primate-specific markers were identified.We validated ETNPPL as a primate-specific NSC marker and verified STMN1 and STMN2 as immature neuron markers in primates.Furthermore,we illustrate a cluster of active astrocytes and microglia exhibiting proinflammatory responses in aged samples.The interaction analysis and the comparative investigation on published datasets and ours imply that astrocytes provide signals inducing the proliferation,quiescence and inflammation of adult NSCs at different stages and that the proinflammatory status of astrocytes probably contributes to the decrease and variability of AHN in adults and elderly individuals. | Wei Wang Mengdi Wang Meng Yang Bo Zeng Wenying Qiu Qiang Ma Xiaoxi Jing Qianqian Zhang Bosong Wang Chonghai Yin Jiyao Zhang Yuxin Ge Yufeng Lu Weizhi Ji Qian Wu Chao Ma Xiaoqun Wang | 2022 | Cell Research2022，32，8： | 2 |
| 6 | Particle Dispersed Ceramic Composite Reinforced with Rare Earth Additions显示文摘 | Xu Chonghai Ai Xing | 2001 | International Journal of Refractory Metals and Hard Materials2001，19，2： | 1 |
| 7 | Reserach on the advanced ceramic die materials and their properties显示文摘 | Chonghai Xu Guangchun Xue Rongbo Zhang | 2008 | Key Engineering Materials2008，375，： | 1 |
| 8 | Global 3He optical model potential below 270 MeV显示文摘 | Liang Chuntian Li Xiaohua Cai Chonghai | 2009 | J Phys2009，36，08： | 1 |
| 9 | Multiphase tailoring and design of an advanced ceramic material 显示文摘 | Xu Chonghai Ai Xing | 2004 | Key Eng Maters2004，，： | 1 |
| 10 | Research and development of rare-earth cemented carbides显示文摘 | Xu Chonghai | 2001 | International Journal of Refractory Metals and Hard Materi- als2001，19，3： | 1 |
| 11 | Calculations for proton-induced reactions below 250 MeV on ^208Pb and ^239Bi targets 显示文摘 | ZHANG Zhengjun SUN Xiuquan CAI Chonghai | 2003 | Nuclear Science and Engineering2003，143，： | 1 |
| 12 | CMUP2-A program for calculating complex reactions of a medium-heavy nucleus with charged particles 显示文摘 | Cai Chonghai Shen Qingbiao | 1992 | Nucl Sci & Eng1992，111，3： | 1 |
| 13 | Research and developmeat of rare earthcemented carbides显示文摘 | Xu Chonghai Ai Xing Huang Chuanzhen | | 0，，01： | 1 |
| 14 | Reseatch and Developmentof rare-earth cemented carbides显示文摘 | Chonghai Xu | 2001 | International Journal of Refractory Metals& Hard Materials2001，，19： | 1 |
| 15 | A single-cell transcriptome atlas of the aging human and macaque retina显示文摘The human retina is a complex neural tissue that detects light and sends visual information to the brain.However,the molecular and cellular processes that underlie aging primate retina remain unclear.Here,we provide a comprehensive transcriptomic atlas based on 119520 single cells of the foveal and peripheral retina of humans and macaques covering different ages.The molecular features of retinal cells differed between the two species,suggesting distinct regional and species specializations of the human and macaque retinae.In addition,human retinal aging occurred in a region-and cell-type-specific manner.Aging of human retina exhibited a foveal to peripheral gradient.MYO9A-rods and a horizontal cell subtype were greatly reduced in aging retina,indicating their vulnerability to aging.Moreover,we generated a dataset showing the cell-type-and region-specific gene expression associated with 55 types of human retinal disease,which provides a foundation to understanding of the molecular and cellular mechanisms underlying human retinal diseases.Such datasets are valuable to understanding of the molecular characteristics of primate retina,as well as molecular regulation of aging progression and related diseases. | Wenyang Yi Yufeng Lu Suijuan Zhong Mei Zhang Le Sun Hao Dong Mengdi Wang Min Wei Haohuan Xie Hongqiang Qu Rongmei Peng Jing Hong Ziqin Yao Yunyun Tong Wei Wang Qiang Ma Zeyuan Liu Yuqian Ma Shouzhen Li Chonghai Yin Jianwei Liu Chao Ma Xiaoqun Wang Qian Wu Tian Xue | 2021 | National Science Review2021，8，4： | 1 |
| 16 | Research on the advanced ceramic die materials and their properlies显示文摘 | XU Chonghai XIAO Guangchun ZHANG Rongbo | 2008 | Key Engineering Materials2008，，： | 1 |
| 17 | Calculation and analysis for p +Ni reactoins below 200 MeV显示文摘 | Liang Chuntian Cai Chonghai | 2007 | Nuclear Science and Engineering2007，157，： | 1 |
| 18 | MEND-a program for calculating the complete set of nuclear Data of medium-heavy nuclei in mediumlow energy region显示文摘 | Cai Chonghai | 2006 | Nuclear Science and Engineering2006，153，： | 1 |
| 19 | Si3N4 BN SiO2 based microwave transparent materials显示文摘 | Zhang Weiru Wang Chonghai Li Ling | 2008 | Key Engineering Materials2008，68，： | 1 |
| 20 | Fabrication and of an advanced ceramic tool material显示文摘 | Chonghai Xu | 2001 | Wear2001，249，： | 1 |
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