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| 1 | Noise simulation in cone beam CT imaging with parallel computing显示文摘 | Tu Shu-Ju Shaw Chris C Chen Lingyun | 2006 | Phys Med Biol2006，51，5： | 1 |
| 2 | Pixdwise Fusion for Optimizing SNR in Multiple - plate Computed Radiography Imaging, 显示文摘 | Tianpeng Wang Chris C Shaw Ching- Chung Li | 1999 | IEEE Transactions on Medical Imaging1999，18，3： | 1 |
| 3 | The toxicity of textile reactive azo dyes after hydrolysis and decoiourisation显示文摘 | Anna Gottlieb Chris Shaw Alan Smith | 2003 | Journal of Biotechnology2003，101，： | 1 |
| 4 | Noise simulation in cone beam CT imaging with parallel computing 显示文摘 | Shu-Ju Tu Chris C Shaw Lingyun Chen | 2006 | Physics in Medicine and Biology2006，51，5： | 1 |
| 5 | The up-regulation of voltage-gated sodium channels subtypes coincides with an increased sodium current in hippocampal neuronal culture model显示文摘 | Feng Guo Xiaoxue Xu Jiqun Cai Huiyuan Hu Wei Sun Guilin He Dongxue Shao Lei Wang Tianbao Chen Chris Shaw Tong Zhu Liying Hao | 2013 | Neurochemistry International2013，，3： | 1 |
| 6 | Evaluation of antimicrobial and anticancer activities of three peptides identified from the skin secretion of Hylarana latouchii显示文摘The skins of frogs of the family Ranidae are particularly rich sources of biologically active peptides, among which antimicrobial peptides (AMPs) constitute the major portion. Some of these have attracted the interest of researchers because they possess both antimicrobial and anticancer activities. In this study, with ‘shotgun’ cloning & MS/MS fragmentation, three AMPs, homologues of family brevinin-1 (brevinin-1HL), & temporin (temporin-HLa and temporin-HLb), were discovered from the skin secretion of the broad-folded frog, Hylarana latouchii. They exhibited various degrees of antimicrobial & antibiofilm activities against test microorganisms & hemolysis on horse erythrocytes. It was found that they could induce bacteria death through disrupting cell membranes & binding to bacterial DNA. In addition, they also showed different potencies towards human cancer cell lines. The secondary structure & physicochemical properties of each peptide were investigated to preliminarily reveal their structure–activity relationships. Circular dichroism spectrometry showed that they all adopted a canonical α-helical conformation in membrane-mimetic solvents. Notably, the prepropeptide of brevinin-1HL from H. latouchii was highly identical to that of brevinin-1GHd from Hylarana guentheri, indicating a close relationship between these two species. Accordingly, this study provides candidates for the design of novel anti-infective & antineoplastic agents to fight multidrug-resistant bacteria & malignant tumors & also offers additional clues for the taxonomy of ranid frogs. | Yan Lin Tianxing Lin Ningna Cheng Shuting Wu Jiancai Huang Xiaoling Chen Tianbao Chen Mei Zhou Lei Wang Chris Shaw | 2021 | Acta Biochimica et Biophysica Sinica2021，53，11： | 0 |
| 7 | REACH compliant epoxides used in the synthesis of Fe(Ⅲ)-based aerogel monoliths for target fabrication显示文摘Aerogel materials manufactured from metal oxides have been used as components in numerous high-energy density physics targets. These aerogels have been identified to be used as a future target material in the AWE fielded campaigns at the US National Ignition Facility. A wide variety of metal oxide aerogels are required for future campaigns and therefore a versatile manufacturing route is sought; as such, an epoxide-assisted sol–gel route was investigated. Under the European Union Registration, Evaluation, Authorization and Restriction of Chemicals legislation, the most commonly used epoxide, propylene oxide, is recognized as a substance of very high concern(SVHC). This work sought to investigate suitable alternative epoxides for use in target manufacture. The outcome was the identification of synthesis routes for stable metal oxide aerogel monoliths using epoxides not subject to the above restrictions. | Alberto Vails Arrufat Magdalena Budziszewska Clement Lopez Aymeric Nguyen Jakub Sitek Paul Jones Chris Shaw Ian Hayes Gareth Cairns Glenn Leighton | 2017 | High Power Laser Science and Engineering2017，5，4： | 0 |
| 8 | 自行车骑行者和道路交通规则:什么是影响决策的因素?显示文摘澳大利亚新南威尔士大学公共卫生和社区医学学院Louise Shaw等对以自行车为主要交通工具的人进行专项研究,结果显示,“行驶在人行道”和“闯红灯”是自行车骑行者最常报道的道路交通违规现象。而落后的基础设施设计是道路交通规则漏洞最大的贡献因素,其次是机动车辆的速度和其他道路使用者的行为。 | Louise Shaw Roslyn G Poulos Julie Hatfield Chris Rissel 帅健 李丽萍 | 2016 | 伤害医学(电子版)2016，5，1： | 0 |
| 9 | Sheng Jiang San, traditional multi-herb formulation, exerts anti-influenza effects in vitro and in vivo via neuraminidaseinhibition and immune regulation显示文摘OBJECTIVE Sheng Jiang San(SJS),a multi-herb formulation,is used in treating high fever,thirsty and anxiety in ancient China and it is sometimes used to treat seasonal influenza in modern.However,there is no evidencebased investigation and mechanism research to support SJS′s anti-influenza efficacy.This study aims to investigate the anti-influenza effect of SJS and its possible mechanisms.METHODS In this study,we examined the inhibitory effect of SJS against different influenza viruses on Madin-Darby canine kidney cells.Influenza virus infected BALB/c mice were employed as in vivo model to evaluate the efficacy.Mice challenged with A/PR/8/34(H1N1)were orally administrated SJS 1 g·kg^-1 daily for seven days and monitored for 14 d.The survival rate,body mass changes,lung index,lung viral load,histopathologic changes and immune-regulation of the mice were measured.The underlying anti-influenza virus mechanisms were studied by a series of biological assays in vitro to determine if hemagglutinin,ribonucleoprotein complex or nerauminidase were targets of SJS.RESULTS SJS exerted a broad spectrum of inhibitory effects on multiple influenza strains in a dose-dependent manner.And IC50 of SJS against A/WSN/33(H1N1)was lower than 35 mg·L^-1.SJS also protected 50%of mice from influenza virus PR8 infection.The lung index and the lung viral load of SJS treated mice were signifi⁃cantly decrease compared with untreated mice.SJS 2 g·L^-1 inhibited 80%of neuraminidase enzymatic activity.SJS also up-regulated TNF-αand IFN-αand down-regulated IL-2 of influenza virus induced mice.CONCLUSION SJS is a useful formulation for treating influenza virus infection. | ZHANG Tian-bo XIAO Meng-jie Chun-Kwok WONG Ka-Pun CHRIS MOK ZHAO Xin TI Hui-hui Pang-Chui SHAW | 2019 | 中国药理学与毒理学杂志2019，33，9： | 0 |
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