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| 1 | Defects and failure types of solid insulation in gas‐insulated switchgear:In situ study and case analysis显示文摘The gas‐insulated switchgear(GIS)has been widely used in modern ultra‐high voltage systems.However,once it fails,its fully enclosed feature brings challenges in its diagnosis and maintenance.As the failure rate of GIS due to insulator failure has been increasing in recent years,it is necessary and important to understand the commonly existing defects presented in the insulator.First,the manufacturing process of GIS insulators is intro-duced here.The defect types commonly existing in the insulator are categorised.The failure of GIS due to insulator defects that occurred in recent years are reviewed and discussed.The content in this study is useful for engineers and scientists to study on the GIS solid insulation defects and their failure mechanisms. | Yunqi Xing Zhiwen Wang Lin Liu Yuan Xu Yang Yang Shan Liu Fusheng Zhou Shun He Chuanyang Li | 2022 | High Voltage2022，7，1： | 4 |
| 2 | Insulating materials for realising carbon neutrality:Opportunities,remaining issues and challenges显示文摘The 2050 carbon-neutral vision spawns a novel energy structure revolution,and the construction of the future energy structure is based on equipment innovation.Insulating material,as the core of electrical power equipment and electrified transportation asset,faces unprecedented challenges and opportunities.The goal of carbon neutral and the urgent need for innovation in electric power equipment and electrification assets are first discussed.The engineering challenges constrained by the insulation system in future electric power equipment/devices and electrified transportation assets are investigated.Insulating materials,including intelligent insulating material,high thermal conductivity insulating material,high energy storage density insulating material,extreme environment resistant insulating material,and environmental-friendly insulating material,are cat-egorised with their scientific issues,opportunities and challenges under the goal of carbon neutrality being discussed.In the context of carbon neutrality,not only improves the understanding of the insulation problems from a macro level,that is,electrical power equipment and electrified transportation asset,but also offers opportunities,remaining issues and challenges from the insulating material level.It is hoped that this paper en-visions the challenges regarding design and reliability of insulations in electrical equipment and electric vehicles in the context of policies towards carbon neutrality rules.The authors also hope that this paper can be helpful in future development and research of novel insulating materials,which promote the realisation of the carbon-neutral vision. | Chuanyang Li Yang Yang Guoqiang Xu Yao Zhou Mengshuo Jia Shaolong Zhong Yu Gao Chanyeop Park Qiang Liu Yalin Wang Shakeel Akram Xiaoliang Zeng Yi Li Fangwei Liang Bin Cui Junpeng Fang Lingling Tang Yulin Zeng Xingtao Hu Jiachen Gao Giovanni Mazzanti Jinliang He Jianxiao Wang Davide Fabiani Gilbert Teyssedre Yang Cao Feipeng Wang Yunlong Zi | 2022 | High Voltage2022，7，4： | 4 |
| 3 | Surface Charging Phenomena on HVDC Spacers for Compressed SF_(6) Insulation and Charge Tailoring Strategies显示文摘Surface flashover of spacers is a key factor limiting the application of HVDC GIS/GIL,while the charge accumula-tion on the surface of the spacer could have a potential adverse effect on the surface flashover voltage.This paper discusses the laws regarding distribution patterns of surface charges and the related mechanisms.The field-dependent property is discussed in detail to comprehensively illustrate the charge transport mecha-nism and explain the research differences regarding different surface charge patterns obtained by previous researchers.In addition,the main surface charge control methods for epoxy resin are summarized and discussed.The potential research directions of charge control methods and key points in manufacturing of spacers used in HVDC GIS/GIL are also explored. | Chuanyang Li Yuan Xu Chuanjie Lin Geng Chen Youping Tu Yao Zhou Zhipeng Lei Tao Han Simone Vincenzo Suraci Jian Wang Weidong Liu M.Tariq Nazir Shun He Andrea Cavallini Giovanni Mazzanti Davide Fabiani Jinliang He | 2020 | CSEE Journal of Power and Energy Systems2020，6，1： | 3 |
| 4 | Investigation of β-Ga2O3 films and β-Ga2O3/GaN heterostructures grown by metal organic chemical vapor deposition显示文摘In this work,(-201)β-Ga2O3 films are grown on GaN substrate by metal organic chemical vapor deposition(MOCVD).It is revealed that theβ-Ga2O3 film grown on GaN possesses superior crystal quality,material homogeneity and surface morphology than the results of common heteroepitaxialβ-Ga2O3 film based on sapphire substrate.Further,the relevance between the crystal quality of epitaxialβ-Ga2O3 film and theβ-Ga2O3/GaN interface behavior is investigated.Transmission electron microscopy result indicates that the interface atom refactoring phenomenon is beneficial to relieve the mismatch strain and improve the crystal quality of subsequentβ-Ga2O3 film.Moreover,the energy band structure ofβ-Ga2O3/GaN heterostructure grown by MOCVD is investigated by X-ray photoelectron spectroscopy and a large conduction band offset of 0.89 eV is obtained.The results in this work not only convincingly demonstrate the advantages ofβ-Ga2O3 films grown on GaN substrate,but also show the great application potential of MOCVDβ-Ga2O3/GaN heterostructures in microelectronic applications. | YaChao Zhang YiFan Li ZhiZhe Wang Rui Guo ShengRui Xu ChuanYang Liu ShengLei Zhao JinCheng Zhang Yue Hao | 2020 | Science China(Physics,Mechanics & Astronomy)2020，63，11： | 2 |
| 5 | Emission factors of particulate matter, CO and CO_2 in the pyrolytic processing of typical electronic wastes显示文摘A self-designed experimental device was employed to simulate the pyrolytic dismantling process of selected electronic wastes(E-wastes), including printed wiring boards(PWBs)and plastic casings. The generated particulate matter(PM) of different particle sizes, carbon monoxide(CO) and carbon dioxide(CO_2) were determined, and the corresponding emission factors(EFs) were estimated. Finer particles with particle sizes of 0.4–2.1 μm accounted for78.9% and 89.3% of PM emitted by the pyrolytic processing of PWBs and plastic casings,respectively, and the corresponding EFs were 9.68 ± 4.81 and 18.49 ± 7.2 g/kg, respectively.The EFs of CO and CO_2 from PWBs and plastic casings were 55.9 ± 26.9 and 1182 ± 439 g/kg,and 133.6 ± 34.6 and 2827 ± 276 g/kg, respectively. Compared with other emission sources,such as coal, biomass, and traffic exhaust, the EFs of E-wastes were relatively higher,especially for PM. There were significant positive correlations(p < 0.05) of the initial contents of carbon and nitrogen in PWBs with the related EFs of PM, CO, and CO_2, while the correlations for plastic casings were insignificant. The EFs of CO of PWBs were significantly positively correlated with the corresponding EFs of PM and the parent polycyclic aromatic hydrocarbons(PAHs); however, the same result was not observed for plastic casings. | Liyuan Chen Chuanyang Cai Shuangyu Yu Yu Liu Shu Tao Wenxin Liu | 2019 | Journal of Environmental Sciences2019，31，7： | 2 |
| 6 | miR-214 inhibits epithelial–mesenchymal transition of breast cancer cells via downregulation of RNF8显示文摘MicroRNAs(miRNAs)are a class of endogenous noncoding genes that regulate gene expression at the posttranscriptional level.In recent decades,miRNAs have been reported to play important roles in tumor growth and metastasis,while some reported functions of a specific miRNA in tumorigenesis are contradictory.In this study,we reevaluated the role of miR-214,which has been reported to serve as an oncogene or anti-oncogene in breast cancer metastasis.We found that miR-214 inhibited breast cancer via targeting RNF8,a newly identified regulator that could promote epithelial–mesenchymal transition(EMT).Specifically,the survival rate of breast cancer patients was positively correlated with miR-214 levels and negatively correlated with RNF8 expression.The overexpression of miR-214 inhibited cell proliferation and invasion of breast cancer,while suppression of miR-214 by chemically modified antagomir enhanced the proliferation and invasion of breast cancer cells.Furthermore,miR-214 could modulate the EMT process via downregulating RNF8.To our knowledge,this is the first report that reveals the role of the miR-214–RNF8 axis in EMT,and our results demonstrate a novel mechanism for miR-214 acting as a tumor suppressor through the regulation of EMT. | Lu Min Chuanyang Liu Jingyu Kuang Xiaomin Wu Lingyun Zhu | 2019 | Acta Biochimica et Biophysica Sinica2019，51，8： | 1 |
| 7 | RNF8 depletion attenuates hepatocellular carcinoma progression by inhibiting epithelial-mesenchymal transition and enhancing drug sensitivity显示文摘Despite substantial advances that have been made in understanding the etiology of hepatocellular carcinoma(HCC),the early-stage diagnosis and treatment of advanced-stage HCC remain a major challenge.RNF8,an E3 ligase important for the DNA damage response,has been proven to facilitate the progression of breast and lung cancer,but its role in HCC remains unclear.In this study,we find that the expression of RNF8 is up-regulated in HCC tissues and positively correlated with poor prognosis of HCC.Furthermore,silencing RNF8 by siRNAs attenuates the migration of HCC cells and inhibits epithelial-mesenchymal transition(EMT)by regulating the expressions of proteins including N-cadherin,β-catenin,snail,and ZO-1.Moreover,Kaplan‒Meier survival analysis shows that high RNF8 expression predicts poor survival benefits from sorafenib.Finally,cell viability assay demonstrates that RNF8 depletion enhances the sensitivity of HCC cells to sorafenib and lenvatinib treatment.We hypothesize that the inhibitory role of RNF8 in EMT and its enhancing effects on anti-cancer drugs orchestrate the protective effects of RNF8 deficiency in HCC,which indicates its potential in clinical application. | Jingyu Kuang Ting Duan Changsong Gao Chuanyang Liu Si Chen Lv-yun Zhu Lu Min Chenyu Lu Wenlun Wang Lingyun Zhu | 2023 | Acta Biochimica et Biophysica Sinica2023，55，4： | 0 |
| 8 | Cassiae Semen improves non-alcoholic fatty liver disease through autophagy-related pathway显示文摘Objective:Cassiae Semen(CS,Juemingzi in Chinese)has been used for thousands of years in ancient Chinese history for relieving constipation,improving liver function as well as preventing myopia.Here we aimed to elucidate the anti-steatosis effect and underlying mechanism of CS against non-alcoholic fatty liver disease(NAFLD).Methods:High-performance liquid chromatography(HPLC)was used to identify the major components of CS water extract.Mice were fed with a high-fat and sugar-water(HFSW)diet to induce hepatic steatosis and then treated with CS.The anti-NAFLD effect was determined by measuring serum biomarkers and histopathology staining.Additionally,the effects of CS on cell viability and lipid metabolism in oleic acid and palmitic acid(OAPA)-treated HepG2 cells were measured.The expression of essential genes and proteins involved in lipid metabolism and autophagy signalings were measured to uncover the underlying mechanism.Results:Five compounds,including aurantio-obtusin,rubrofusarin gentiobioside,cassiaside C,emodin and rhein were simultaneously identified in CS extract.CS not only improved the diet-induced hepatic steatosis in vivo,as indicated by decreased number and size of lipid droplets,hepatic and serum triglycerides(TG)levels,but also markedly attenuated the OAPA-induced lipid accumulation in hepatocytes.These lipid-lowering effects induced by CS were largely dependent on the inhibition of fatty acid synthase(FASN)and the activation of autophagy-related signaling,including AMP-activated protein kinase(AMPK),light chain 3-II(LC3-II)/LC3-1 and autophagy-related gene5(ATG5).Conclusion:Our study suggested that CS effectively protected liver steatosis via decreasing FASN-related fatty acid synthesis and activating AMPK-mediated autophagy,which might become a promising therapeutic strategy for relieving NAFLD. | Mingning Ding Fei Zhou Yijie Li Chuanyang Liu Yiqing Gu Jianzhi Wu Guifang Fan Yajing Li Xiaojiaoyang Li | 2023 | Chinese Herbal Medicines2023，15，3： | 0 |
| 9 | Insight into fluorescence properties of 14 selected toxic single-ring aromatic compounds in water:Experimental and DFT study显示文摘Various single-ring aromatic compounds in water sources are of great concern due to its hazardous impact on the environment and human health.The fluorescence excitation-emission matrix(EEMs)spectrophotometry is a useftil method to identify organic pollutants in water.This study provides a detailed insight into the fluorescence properties of the 14 selected toxic single-ring aromatic compounds by experimental and theoretical analysis.The theoretical analysis were done with Time-Dependent Density Functional Theory(TD-DFT)and B3LYP/6-31G(d,p)basis set,whereas,Polarizable Continuum Model(PCM)was used to consider water as solvent.The selected compounds displayed their own specific excitation-emission(Ex/Em)wavelengths region,at Ex<280 nm and Em<340 nm,respectively.Whereas the theoretical Ex/Em was observed as.Ex at 240 nm-260 nm and Em at 255 nm-300 nm.Aniline as a strong aromatic base has longer Em(340 nm)than alkyl,carbonyl,and halogens substituted benzenes.The lone pair of electrons at amide substituent serves as a 7r-electron contributor into the aromatic ring,hence increasing the stability and transition energy,which results in longer emission and low quantum yield for the aniline.The fluorescence of halogenated benzenes illustrates an increase in the HOMO-LUMO energy gap and a decrease in quantum yield associated with atomic size(F>Cl>Br>I).In this study the theoretical results are in line with experimental ones.The understanding of fluorescence and photophysical properties are of great importance in the identification of these compounds in the water. | Muhammad Farooq Saleem Khan Jing Wu Cheng Cheng Mona Akbar Bo Liu Chuanyang Liu Jian Shen Yu Xin | 2020 | Frontiers of Environmental Science & Engineering2020，14，3： | 0 |
| 10 | Line Fault Detection of DC Distribution Networks Using the Artificial Neural Network显示文摘ADC distribution network is an effective solution for increasing renewable energy utilization with distinct benefits,such as high efficiency and easy control.However,a sudden increase in the current after the occurrence of faults in the network may adversely affect network stability.This study proposes an artificial neural network(ANN)-based fault detection and protection method for DC distribution networks.The ANN is applied to a classifier for different faults ontheDC line.The backpropagationneuralnetwork is used to predict the line current,and the fault detection threshold is obtained on the basis of the difference between the predicted current and the actual current.The proposed method only uses local signals,with no requirement of a strict communication link.Simulation experiments are conducted for the proposed algorithm on a two-terminal DC distribution network modeled in the PSCAD/EMTDC and developed on the MATLAB platform.The results confirm that the proposed method can accurately detect and classify line faults within a few milliseconds and is not affected by fault locations,fault resistance,noise,and communication delay. | Xunyou Zhang Chuanyang Liu Zuo Sun | 2023 | Energy Engineering2023，120，7： | 0 |
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