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| 1 | Experimental Research on Sewage Outfall Diffusers显示文摘The influence of diffuser parameters, including the riser spacing, port number in a riser, injection angle, port arrangement, etc., on the surface initial dilution is experimentally investigated. The relative density difference between the effluent and the sea water in the model is the same as that in the prototype, and the effect of the cross current is simulated by an inverse model technique. Based on the result analysis, the arrangement with more ports in a riser and larger riser spacing is suggested to save construction cost. The relationship between the Reynolds number based on the port diameter and velocity, and the surface initial dilution is also explored, and the critical Reynolds number is proposed. | Jiang Chuanfeng , Yan Zhongmin , Zhou Chuntian and Liu Mingming Professor, Res. Inst. of Water Resources and Hydro-Electric Power, Hohai University, Nanjing 210024 Senior Engineer, Res. Inst. of Water Resources and Hydro-Electric Power, Hohai University, Nanjing 210024 Engineer, Res. Inst. of Water Resources and Hydro-Electric Power, Hohai University, Nanjing 210024 | 1995 | China Ocean Engineering1995，10，2： | 13 |
| 2 | The outbreak of rabbit hemorrhagic virus type 2 in the interior of China may be related to imported semen显示文摘Dear Editor,Rabbit hemorrhagic disease(RHD)is a fatal infectious disease that primarily affects adult rabbits and causes great economic losses in the rabbit industry(Mitro and Krauss,1993).The causative pathogen is rabbit hemorrhagic disease virus(RHDV),which belongs to the genus Lagovirus and the family Calicivirus(Moussa et al.,1992).In 1984,RHDV was first documented in China. | Ruibin Qi Chunchun Meng Jie Zhu Hang Li Qiuhong Miao Jingyu Tang Aoxing Tang Hongyuan Guo Chuncao Liu Chuanfeng Li Zongyan Chen Fang Wang Qinwen Zhang Guangqing Liu | 2022 | Virologica Sinica2022，37，4： | 3 |
| 3 | Impact of switching frequencies on the TID response of SiC power MOSFETs显示文摘Different switching frequencies are required when SiC metal-oxide-semiconductor field-effect transistors(MOSFETs)are switching in a space environment.In this study,the total ionizing dose(TID)responses of SiC power MOSFETs are investigated under different switching frequencies from 1 kHz to 10 MHz.A significant shift was observed in the threshold voltage as the frequency increased,which resulted in premature failure of the drain-source breakdown voltage and drain-source leakage current.The degradation is attributed to the high activation and low recovery rates of traps at high frequencies.The results of this study suggest that a targeted TID irradiation test evaluation method can be developed according to the actual switching frequency of SiC power MOSFETs. | Sheng Yang Xiaowen Liang Jiangwei Cui Qiwen Zheng Jing Sun Mohan Liu Dang Zhang Haonan Feng Xuefeng Yu Chuanfeng Xiang Yudong Li Qi Guo | 2021 | Journal of Semiconductors2021，42，8： | 2 |
| 4 | A selective fluorescent probe for La3 + and Y3 + based on calixarene显示文摘 | Junmin Liu Chuanfeng Chen Qiyu Zheng | 2004 | Tetrahedron Letters2004，45，： | 1 |
| 5 | A selective fluorescent probe for La3+ and Y3+ based on calixarene显示文摘 | Liu Junmin Chen Chuanfeng Zheng Qiyu | 2004 | Tetrahedron Letters2004，45，： | 1 |
| 6 | Recombinant adenovirus expressing F and H fusion proteins of peste des petits ruminants virus induces both humoral and cell-mediated immune responses in goats显示文摘 | Yong Wang Guangqing Liu Zongyan Chen Chuanfeng Li Lijun Shi Wenchao Li Huaxin Huang Chunai Tao Chaofei Cheng Binrui Xu Gang Li | 2013 | Veterinary Immunology and Immunopathology . 2013 (1-2)2013，，： | 1 |
| 7 | Antioxidant and hepatoprotective effect of different extracts of Guizhencao (Herba Bidentis Bipinnatae) against liver injury in hyperlipidemia rats显示文摘OBJEVTIVE: To investigate the antioxidant and hepatoprotective properties of the different extracts Guizhencao (Herba Bidentis Bipinnatae) against liver injury in hyperlipidemia rats. METHODS: The rats were divided into 7 groups, with 10 rats in each. Rats were treated with high-fat diet for 18 weeks besides the normal control group, then rats in both normal control and model groups were received 5 mL/kg -1 · day -1 of saline and those in the positive control group with 2 mg/kg -1 · day -1 of lovastatin. Rats in the positive control group and different Guizhencao (Herba Bidentis Bipinnatae) extracts treatment groups (ethyl acetate extract group, n-hexane extract group, ethanol extract group, and aqueous extract group) were treated with corresponding extract at a concentration of 5 mL/kg -1 · day -1 . After 8 weeks treatment, all rats were sacrificed and total blood samples were collected. Histological analysis of liver was underdone by hematoxylin and eosin. The levels of serum ala-nine aminotransferase (ALT), aspartate aminotransferase (AST), glouse (GLU), cholesterol (TC), triglycerides (TG), low-density lipoprotein-cholesterol (LDL-C) and high-density lipoprotein-cholesterol were measured according to standard procedure using auto-analyzer. The superoxide dismutase (SOD) and malondialdehyde (MDA) levels in liver were ananlyzed by procedure instruction. RESULTS: The histopathological analysis implied that the administration of Guizhencao (HerbaBidentis Bipinnatae) extracts resulted in hepatoprotective role compared with that of the model group. In addition, the high-fat diet caused a remarkable increase of ALT, AST, GLU, TC, TG, LDL-C and MDA levels. A decline in HDL-C and SOD concentrations and a reversal of effects were observed in different Guizhencao (Herba Bidentis Bipinnatae) extracts groups, especially in the aqueous extract and ethanol extract groups. CONCLUSION: The different extracts of Guizhencao (Herba Bidentis Bipinnatae) can play a protecting role against liver injury in hyperlipidemia rats maybe through decreasing ALT, AST, GLU, TC, TG, LDL-C and MDA levels and enhancing the liver anti-oxidative ability. | Xichao Xia Yuhong Ma Xiankun Xing Chuanfeng Huang Ling Li Gaixia Gui Qingchun Liu Shipeng Xue | 2013 | Journal of Traditional Chinese Medicine2013，33，4： | 1 |
| 8 | Host-guest co-assembly triggered turn-on and ratiometric sensing of berberine and its detoxicating显示文摘Fluorescent sensing for specific detection of berberine is an important issue in view of its potential jeopardization to food safety and human health,but remains less investigated.To the best of our knowledge,there is no fluorescence turn-on and ratiometric sensors available for specific detection of berberine.In this study,calix[4]carbazole(3)has been synthesized and its property of recognizing berberine ha s been evaluated by UV-vis,fluorescence,NMR,DLS and TEM techniques.The results show that 3 selectively recognizes berberine among the tested drugs and detects it with turn-on and ratiometric fluorescence due to their co-assembly nature.Moreover,3 is not only low toxic and can reduce toxicity of berberine to human normal liver L02 cell,but also can release berberine to tumor HepG2 cells at acid micro-environment.It therefore holds a great potential for further exploration。 | Chuanfeng Liu Zhixin Li Hai Yu Naibin Cui Xiaoyu Liao Haibin Zhang Zhengning Shu Peng Yang | 2021 | Chinese Chemical Letters2021，32，4： | 1 |
| 9 | MiR-34a in age and tissue related radio-sensitivity and serum miR-34a as a novel indicator of radiationinjury显示文摘 | Cong Liu Chuanfeng Zhou Fu Gao | 2011 | IntJBiolSci2011，7，2： | 1 |
| 10 | Biomarkers measured by cytokinesis-block micronucleus cytome assay for evaluating genetic damages induced by polycyclic aromatic hydrocarbons显示文摘 | Huawei Duan Shuguang Leng Zufei Pan Yufei Dai Yong Niu Chuanfeng Huang Ping Bin Yadong Wang Qingjun Liu Wen Chen Yuxin Zheng | 2009 | MutRes-Genetic Toxicology and Environmental Mutagenesis2009，，1： | 1 |
| 11 | MiR-34a in age and tissue related radio-sensitivity and serum miR-34a as a novel indicator of radiation injury显示文摘 | Liu Cong Zhou Chuanfeng Gao Fu | | 0，，02： | 1 |
| 12 | Recombinant adenovirus expressing F and H fusion proteins of peste des petits ruminants virus induces both humoral and cell-mediated immune responses in goats显示文摘 | Yong Wang Guangqing Liu Zongyan Chen Chuanfeng Li Lijun Shi Wenchao Li Huaxin Huang Chunai Tao Chaofei Cheng Binrui Xu Gang Li | 2013 | Veterinary Immunology and Immunopathology (-)2013，，1： | 1 |
| 13 | Assessment of Global Weather Disasters in 2000 | LIU Chuanfeng (National Climate Center, Beijing 100081, China) | 2001 | Natural Disaster Reduction in China2001，，4： | 0 |
| 14 | Identification of in vivo interaction between rabbit hemorrhagic disease virus capsid protein and minor structural protein显示文摘We investigated the ability of the rabbit hemorrhagic disease virus(RHDV) capsid protein(VP60) to interact specifically with the minor structural protein VP10,using an in vivo cell-based CheckMate Mammalian Two-Hybrid System.RHDV VP60 protein interacted specifically with VP10.Immunofluorescence analysis and co-immunoprecipitation with specific antibodies revealed the existence of biologically important VP60/VP10 complexes.However,when VP60 was divided into two fragments,the interaction between VP60 and VP10 was impaired dramatically.These results will be helpful for further investigating the mechanism of RHDV particle assembly. | YANG ZongWei NI Zheng YUN Tao CHEN ZongYan LI ChuanFeng LIU GuangQing | 2012 | Chinese Science Bulletin2012，57，30： | 0 |
| 15 | Development of Novel Resid Hydrometallization Catalyst RDM-3显示文摘基于残油 hydrodemetallization 的反应机制,一个新催化剂搬运人被设计并且准备。作为与催化剂搬运人的类似的类型相比,说的新搬运人展示了更高的毛孔卷,一条更大的毛孔直径和更弱的表面酸味,它能改进散开性能和催化剂的稳定的反应性能。活跃金属部件被一种新技术为更好的金属分散在说的搬运人上装载,这样新催化剂的杂质移动率, RDM-3,显著地被改进。RDM-3 催化剂的商业测试证明催化剂准备的过程是稳定的,催化剂表演比因此,在实验室准备的催化剂稍微好催化剂能在商业规模被生产。 | Hu Dawei Niu Chuanfeng Yang Qinghe Liu Tao | 2007 | China Petroleum Processing & Petrochemical Technology2007，9，4： | 0 |
| 16 | Macro-and Micro-physical Characteristics of Different Parts of Mixed Convective-stratiform Clouds and Differences in Their Responses to Seeding显示文摘This study investigates the cloud macro-and micro-physical characteristics in the convective and stratiform regions and their different responses to the seeding for mixed convective-stratiform clouds that occurred in Shandong province on 21 May 2018,based on the observations from the aircraft,the Suomi National Polar-Orbiting Partnership(NPP)satellite,and the high-resolution Himawari-8(H8)satellite.The aircraft observations show that convection was deeper and radar echoes were significantly enhanced with higher tops in response to seeding in the convective region.This is linked with the conversion of supercooled liquid droplets to ice crystals with released latent heat,resulting in strengthened updrafts,enhanced radar echoes,higher cloud tops,and more and larger precipitation particles.In contrast,in the stratiform cloud region,after the Silver Iodide(AgI)seeding,the radar echoes become significantly weaker at heights close to the seeding layer,with the echo tops lowered by 1.4–1.7 km.In addition,a hollow structure appears at the height of 6.2–7.8 km with a depth of about 1.6 km and a diameter of about 5.5 km,and features such as icing seeding tracks appear.These suggest that the transformation between droplets and ice particles was accelerated by the seeding in the stratiform part.The NPP and H8 satellites also show that convective activity was stronger in the convective region after seeding;while in the stratiform region,a cloud seeding track with a width of 1–3 km appears 10 km downstream of the seeding layer 15 minutes after the AgI seeding,which moves along the wind direction as width increases. | Dejun LI Chuanfeng ZHAO Peiren LI Cao Liu Dianli GONG Siyao LIU Zhengteng YUAN Yingying CHEN | 2022 | Advances in Atmospheric Sciences2022，39，12： | 0 |
| 17 | Emerging drug design strategies in anti-influenza drug discovery显示文摘Influenza is an acute respiratory infection caused by influenza viruses(IFV),According to the World Health Organization(WHO),seasonal IFV epidemics result in approximately 3-5 million cases of severe illness,leading to about half a million deaths worldwide,along with severe economic losses and social burdens.Unfortunately,frequent mutations in IFV lead to a certain lag in vaccine development as well as resistance to existing antiviral drugs.Therefore,it is of great importance to develop anti-IFV drugs with high efficiency against wild-type and resistant strains,needed in the fight against current and future outbreaks caused by different IFV strains.In this review,we summarize general strategies used for the discovery and development of antiviral agents targeting multiple IFV strains(including those resistant to available drugs).Structure-based drug design,mechanism-based drug design,multivalent interaction-based drug design and drug repurposing are amongst the most relevant strategies that provide a framework for the development of antiviral drugs targeting IFV. | Chuanfeng Liu Lide Hu Guanyu Dong Ying Zhang Edeildo Ferreira da Silva-Jinior Xinyong Liu Luis Menendez-Arias Peng Zhan | 2023 | Acta Pharmaceutica Sinica B2023，13，12： | 0 |
| 18 | Comparison of the Anthropogenic Emission Inventory for CMIP6 Models with a Country-Level Inventory over China and the Simulations of the Aerosol Properties显示文摘Anthropogenic emission inventory for aerosols and reactive gases is crucial to the estimation of aerosol radiative forcing and climate effects.Here,the anthropogenic emission inventory for AerChemMIP,endorsed by CMIP6,is briefly introduced.The CMIP6 inventory is compared with a country-level inventory(i.e.,MEIC)over China from 1986 to 2015.Discrepancies are found in the yearly trends of the two inventories,especially after 2006.The yearly trends of the aerosol burdens simulated by CESM2 using the two inventories follow their emission trends and deviate after the mid-2000s,while the simulated aerosol optical depths(AODs)show similar trends.The difference between the simulated AODs is much smaller than the difference between model and observation.Although the simulated AODs agree with the MODIS satellite retrievals for country-wide average,the good agreement is an offset between the underestimation in eastern China and the overestimation in western China.Low-biased precursor gas of SO_(2),overly strong convergence of the wind field,overly strong dilution and transport by summer monsoon circulation,too much wet scavenging by precipitation,and overly weak aerosol swelling due to low-biased relative humidity are suggested to be responsible for the underestimated AOD in eastern China.This indicates that the influence of the emission inventory uncertainties on simulated aerosol properties can be overwhelmed by model biases of meteorology and aerosol processes.It is necessary for climate models to perform reasonably well in the dynamical,physical,and chemical processes that would influence aerosol simulations. | Tianyi FAN Xiaohong LIU Chenglai WU Qiang ZHANG Chuanfeng ZHAO Xin YANG Yanglian LI | 2022 | Advances in Atmospheric Sciences2022，39，1： | 0 |
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