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| 1 | A Novel Feature-based Method for Sentiment Analysis of Chinese Product Reviews显示文摘Sentiment analysis of online reviews and other user generated content is an important research problem for its wide range of applications.In this paper,we propose a feature-based vector model and a novel weighting algorithm for sentiment analysis of Chinese product reviews.Specifically,an opinionated document is modeled by a set of feature-based vectors and corresponding weights.Different from previous work,our model considers modifying relationships between words and contains rich sentiment strength descriptions which are represented by adverbs of degree and punctuations.Dependency parsing is applied to construct the feature vectors.A novel feature weighting algorithm is proposed for supervised sentiment classification based on rich sentiment strength related information.The experimental results demonstrate the effectiveness of the proposed method compared with a state of the art method using term level weighting algorithms. | LIU Lizhen SONG Wei WANG Hanshi LI Chuchu LU Jingli | 2014 | China Communications2014，11，3： | 5 |
| 2 | Mobility in China,2020:a tale of four phases显示文摘2020 was an unprecedented year;with rapid and drastic changes in human mobility due to the COVID-19 pandemic.To understand the variation in commuting patterns among the Chinese population across stable and unstable periods,we used nationwide mobility data from 318 million mobile phone users in China to examine the extreme fluctuations of population movements in 2020,ranging from the Lunar New Year travel season(chunyun),to the exceptional calm of COVID-19 lockdown,and then to the recovery period.We observed that cross-city movements;which increased substantially in chunyun and then dropped sharply during the lockdown,are primarily dependent on travel distance and the socio-economic development of cities.Following the Lunar New Year holiday,national mobility remained low until mid-February,and COVID-19 interventions delayed more than 72.89 million people returning to large cities.Mobility network analysis revealed clusters of highly connected cities,conforming to the social-economic division of urban agglomerations in China.While the mass migration back to large cities was delayed,smaller cities connected more densely to form new clusters.During the recovery period after travel restrictions were lifted,the netflows of over 55%city pairs reversed in direction compared to before the lockdown.These findings offer the most comprehensive picture of Chinese mobility at fine resolution across various scenarios in China and are of critical importance for decision making regarding future public-health-emergency response,transportation planning and regional economic development,among others. | Suoyi Tan Shengjie Lai Fan Fang Ziqiang Cao Bin Sai Bing Song Bitao Dai Shuhui Guo Chuchu Liu Mengsi Cai Tong Wang Mengning Wang Jiaxu Li Saran Chen Shuo Qin Jessica R.Floyd Zhidong Cao Jing Tan Xin Sun Tao Zhou Wei Zhang Andrew J.Tatem Petter Holme Xiaohong Chen Xin Lu | 2021 | National Science Review2021，8，11： | 3 |
| 3 | Genetic mutations and molecular mechanisms of Fuchs endothelial corneal dystrophy显示文摘Background:Fuchs endothelial corneal dystrophy is a hereditary disease and the most frequent cause of corneal transplantation in the worldwide.Its main clinical signs are an accelerated decrease in the number of endothelial cells,thickening of Descemet’s membrane and formation of guttae in the extracellular matrix.The cornea’s ability to maintain stromal dehydration is impaired,causing painful epithelial bullae and loss of vision at the point when the amount of corneal endothelial cells cannot be compensated.At present,apart from corneal transplantation,there is no other effective treatment that prevents blindness.Main text:In this review,we first summarized the mutations of COL8A2,TCF4,TCF8,SLC4A11 and AGBL1 genes in Fuchs endothelial corneal dystrophy.The molecular mechanisms associated with Fuchs endothelial corneal dystrophy,such as endoplasmic reticulum stress and unfolded protein response pathway,oxidative stress,mitochondrial dysregulation pathway,apoptosis pathway,mitophagy,epithelial-mesenchymal transition pathway,RNA toxicity and repeat-associated non-ATG translation,and other pathogenesis,were then explored.Finally,we discussed several potential treatments related to the pathogenesis of Fuchs endothelial corneal dystrophy,which may be the focus of future research.Conclusions:The pathogenesis of Fuchs endothelial corneal dystrophy is very complicated.Currently,corneal transplantation is an important method in the treatment of Fuchs endothelial corneal dystrophy.It is necessary to continuously explore the pathogenesis of Fuchs endothelial corneal dystrophy and establish the scientific foundations for the development of next-generation corneal therapeutics. | Xuerui Liu Tao Zheng Chuchu Zhao Yi Zhang Hanruo Liu Liyuan Wang Ping Liu | 2021 | Eye and Vision2021，8，1： | 2 |
| 4 | NIR-II driven plasmon-enhanced cascade reaction for tumor microenvironment-regulated catalytic therapy based on bio-breakable Au-Ag nanozyme显示文摘Emerging nanozymes with natural enzyme-mimicking catalytic activities have inspired extensive research interests due to their high stability,low cost,and simple preparation,especially in the field of catalytic tumor therapy.Here,bio-breakable nanozymes based on glucose-oxidase(GOx)-loaded biomimetic Au–Ag hollow nanotriangles(Au–Ag–GOx HTNs)are designed,and they trigger an near-infrared(NIR)-II-driven plasmon-enhanced cascade catalytic reaction through regulating tumor microenvironment(TME)for highly efficient tumor therapy.Firstly,GOx can effectively trigger the generation of gluconic acid(H+)and hydrogen peroxide(H2O2),thus depleting nutrients in the tumor cells as well as modifying TME to provide conditions for subsequent peroxidase(POD)-like activity.Secondly,NIR-II induced surface plasmon resonance can induce hot electrons to enhance the catalytic activity of Au–Ag–GOx HTNs,eventually boosting the generation of hydroxyl radicals(•OH).Interestingly,the generated H2O2 and H+can simultaneously induce the degradation of Ag nanoprisms to break the intact triangle nanostructure,thus promoting the excretion of Au–Ag–GOx HTNs to avoid the potential risks of drug metabolism.Overall,the NIR-II driven plasmon-enhanced catalytic mechanism of this bio-breakable nanozyme provides a promising approach for the development of nanozymes in tumor therapy. | Min Xu Qianglan Lu Yiling Song Lifang Yang Chuchu Ren Wen Li Ping Liu Yule Wang Yan Zhu Nan Li | 2020 | Nano Research2020，13，8： | 1 |
| 5 | Spermine increases bactericidal activity of silver-nanoparticles against clinical methicillin-resistant Staphylococcus aureus显示文摘Methicillin-resistant Staphylococcus aureus(MRSA) has emerged worldwide as a major multidrugresistant pathogen that causes notable morbidity and mortality. Fast emerging of MRSA prevalence requires special attention for strengthening the inventory of antimicrobial compounds. Silver nanoparticles(AgNPs) have been widely used to treat multi-drug resistant pathogens due to the unique antibacterial properties, meanwhile spermine has been proven to exert outstanding inhibition effect to S.aureus with not yet fully understood mechanisms. The aim of this study was to investigate the synergistic effect of AgNPs and spermine as well as to determine the antibacterial activity of their combination against MRSA strains. Several clinical MRSA isolates and ATCC BAA-1026 were used to determine minimum inhibitory concentration(MIC) and fractional inhibitory concentration indices(FICI) of AgNPs and spermine, and a synergistic effect was observed. This phenomenon was further confirmed by growth curve and time-killing assays, showed that spermine could be used as an adjuvant for AgNPs in the treatment of MRSA infections. | Chang Liu Han Shen Su Wang Xiaoli Cao Hongpan Xu Yanyan Xia Tingting Bai Yufeng Liu Lijun Peng Chuchu Li Zhirui Guo Zhiyang Li | 2018 | Chinese Chemical Letters2018，29，12： | 1 |
| 6 | Tailored boron phosphate monolithic foam with multimodal hierarchically porous structure and its applications显示文摘The synthesis of multimodal hierarchically porous materials is of great challenge by facile approach.Herein,we assemble BPO_(4) hollow spheres into macroscopic foam materials with multimodal hierarchically porous structure by combining down-to-up process and Ostwald ripening effect.Tailored monolithic B_(2)O_(3)@BPO_(4) foams were obtained from a sticky hydrogel precursor by a one-step annealing process.The foam has the self-supporting frame of BPO_(4) hollow spheres with covering B_(2)O_(3) nanowires and shows excellent permeability and relatively high surface area due to hierarchical structure.The formation mechanism of monolithic B_(2)O_(3)@BPO_(4) foams mainly undergoes inflation,particle aggregation,and Ostwald ripening process.Monolithic foams exhibit superior catalytic activity in oxidation dehydrogenation of alkanes due to the sufficient exposure of active sites over the special frame structure.Furthermore,various monolithic functionalized BPO_(4) foam composites can be easily synthesized and exhibit superior performance in different applications including the oxidation of carbon monoxide,and the self-driven removal of organic pollutants.More interestingly,we also found the sticky hydrogel precursor possesses good heat shielding effect.This work provides a new insight for constructing multimodal hierarchically porous materials with the remaining superior property of nanoscale to cope with various challenges. | Qiuwen Liu Qiang Liu Yawei Wu Renyou Zeng Fangshu Xing ChuChu Cheng Huibin Qiu Caijin Huang | 2022 | Nano Research2022，15，7： | 0 |
| 7 | Micro/nanoelectrode-based electrochemical methodology for single cell and organelle analysis显示文摘Cells are the basic unit of life.Electrochemical analysis of single cells/organelles is essential for uncovering the molecular mechanisms of physiological and pathological processes that are difficult to elucidate on a larger scale.This paper provides an overview of the commonly used fabrication methods for micro/nanoelectrodes applied in the investigations of single cells/organelles as well as the corresponding electrochemical measurements over the last four years including extracellular measurement,combination of extra and intracellular measurement,intracellular reactive oxygen species and reactive nitrogen species(ROS/RNS)measurement,and isolated organelles measurement. | Chuchu Xu De Yang Yuchan Wang Ruolin Liu Fan Wang Zhongqun Tian Keke Hu | 2024 | Nano Research2024，17，1： | 0 |
| 8 | Exploration of the mechanism of cavitation vortex rope and vortex development in the draft tube of tubular turbine units显示文摘Draft tube vortex rope is considered a special cavitation flow phenomenon in tubular turbine units.Cavitation vortex rope is one of the most detrimental factors affecting the safety of hydraulic turbines.In this study,ANSYS CFX software was utilized to numerically simulate the internal cavitation flow of a hydraulic turbine draft tube.The evolution of the cavitation vortex core was characterized by vortex line distribution and vorticity transport equation.The shape and number of blades influenced the revolving direction and distribution characteristics of the vortex close to the runner cone,which formed a counterclockwise-clockwise-counterclockwise distribution pattern.Simultaneously,there were many secondary flows in the draft tube.Mutual cancellation and dissipation between the flows was one of the reasons for reduction in vorticity.When the cross-sectional shape of the draft tube was changed,the vorticity was distributed from the center of the vortex rope to all parts of the cross-sectional draft tube,with extreme values at the center and at the walls.The vortex stretching and dilatation terms played a major role in the change in vorticity,with the baroclinic torque having an effect at the center of the vortex rope,this study is helpful to understand the flow of water in the draft tube and guide the design and optimization of the draft tube in engineering application. | Chuang Cheng Zhenggui Li Changrong Shen Shenglong Gu Chuchu Zeng Chuanzheng Bai Meng Liu Junfeng Hu | 2024 | International Journal of Agricultural and Biological Engineering2024，17，1： | 0 |
| 9 | Improving sentiment analysis accuracy with emoji embedding显示文摘Due to the diversity and variability of Chinese syntax and semantics,accurately identifying and distinguishing individual emotions from online texts is challenging.To overcome this limitation,we incorporate a new source of individual sentiment,emojis,which contain thousands of graphic symbols and are increasingly being used for expressing emotion in online conversations.We examined popular sentiment analysis algorithms,including rule-based and classification algorithms,to evaluate the impact of supplementing emojis as additional features to improve the algorithm performance.Emojis were also translated into corresponding sentiment words when con-structing features for comparison with those directly generated from emoji label words.In addition,considering different functions of emojis in texts,we classified all posts in the dataset by their emoji usage and examined the changes in algorithm performance.We found that emojis are effective as expanding features for improving the accuracy of sentiment analysis algorithms,and the algorithm performance can be further increased by taking different emoji usages into consideration.In this study,we developed an improved emoji-embedding model based on Bi-LSTM(namely,CEmo-LSTM),which achieves the highest accuracy(around 0.95)when analyzing online Chinese texts.We applied the CEmo-LSTM algorithm to a large dataset collected from Weibo from December 1,2019 to March 20,2020 to understand the sentiment evolution of online users during the COVID-19 pandemic.We found that the pandemic remarkably impacted individual sentiments and caused more passive emotions(e.g.,horror and sadness).Our novel emoji-embedding algorithm creatively combined emojis as well as emoji usage with the sentiment analysis model and can handle emotion mining tasks more effectively and efficiently. | Chuchu Liu Fan Fang Xu Lin Tie Cai Xu Tan Jianguo Liu Xin Lu | 2021 | Journal of Safety Science and Resilience2021，2，4： | 0 |
| 10 | Exploring the anti-aging effects of chlorogenic acid and the underlying mechanisms based on a Caenorhabditis elegans model显示文摘Objective:To explore the anti-aging effects of chlorogenic acid(CGA)and the underlying mechanisms based on a Caenorhabditis elegans(C.elegans)model.Methods:The anti-agingactivityofCGAwasstudied basedon thebodylength,exercisebehavior,lipofuscin content,antioxidative stress ability,swallowing frequency,body-bending frequency,and head-swinging ability of C.elegans.Through DAF-16 nuclear translocation and SOD-3-GFP fluorescence experiments,the effects of CGA on ROS levels,antioxidant enzyme activities,MDA content,mutant-strain lifespan,and anti-aging molecular signaling pathways were explored,as well as the underlying mechanisms.Results:CGA improved multiple indices of the nematode:body length was increased(all P<0.001),head-swing frequency and body-bending frequency were increased(all P<0.05),nematode longevity was prolonged(P=0.0021),lipofuscin deposition in nematodes was slowed down(all P<0.001),the chemotaxis index was improved(P=0.0012),ROS levels were reduced(all P<.001),and SOD activity and MDA content were reduced(SOD:P=0.0017 between the low-concentration group and the control group,P<.001 between the high-concentration and medium-concentration groups and the control group;MDA:P=0.0135 between the low-concentration group and the control group,and P<0.001 between the high-concentration and medium-concentration groups and the control group).In addition,CGA also activated the DAF-16 transcription factor,promoted DAF-16 nuclear translocation under oxidative stress conditions(both P<0.001 between the high-concentration and medium-concentration groups and the control group),and increased SOD-3 gene expression in nematodes(all P<0.001).Conclusion:CGA plays an anti-aging role in C.elegans.The underlying mechanisms include activation of the insulin/IGF-1 signaling pathway and enhancement of DAF-16 activity.This study lays a foundation for further research into the anti-aging effects of CGA. | Yuqian Yang Xu Chen Danyang Ye Chuanyu Wei Xinxin Pang Chuchu Kong Yongsheng Fang Hongliu Yang Yuanyuan Zhang Yonggang Liu | 2023 | Journal of Traditional Chinese Medical Sciences2023，10，2： | 0 |
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