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| 1 | Identification and characterization of microRNAs in raw milk during different periods of lactation, commercial fluid, and powdered milk products显示文摘最近的婴儿的公式奶粉污染事件证明了在牛奶质量控制的经典标记或标准在识别鈥渕a nipulated 鈥 ? 是不够的差质量的牛奶。在现在的学习,我们第一次证明奶牛牛奶包含大量 microRNAs ( miRNAs )并且牛奶特定的 miRNAs 的唯一的表示侧面能为未加工的牛奶和牛奶相关的商业产品的质量控制用作新奇指示物和可能的新标准,例如液体牛奶和粉状的公式牛奶。用定序的 Solexa,首先,我们系统地在未加工的牛奶屏蔽了 miRNA 表示并且在未加工的牛奶识别了 245 miRNAs 的一个总数。不同于层次在哺乳的不同时期是其表达式将近相同的另外的经典 biomarkers,单个 miRNAs 能显著地在哺乳过程期间被改变,含有那 miRNAs 可以是更精确的指示物反映牛奶的优秀改变。第二,使用 TaqMan 基于探查的 miRNA 量的 RT-PCR ,我们进一步识别了七 miRNAs 重要地在整个哺乳过程,和更多有相对一致的表情,这七牛奶特定的 miRNAs 的表示侧面能为区别用作理想的 biomarker 差质量或从纯未加工的牛奶的 鈥渕a nipulated 鈥?牛奶,象为商业乳制品的质量控制一样,例如液体,牛奶和粉状的公式挤。一起,我们的调查结果为为决定未加工的牛奶或牛奶相关的商业产品的质量理解牛奶 miRNAs 和一个新潜在的标准的生理的角色提供一个基础。 | Xi Chen Chao Gao Haijin Li Lei Huang Qi Sun Yanye Dong Chunliang Tian Shengpu Gao Hailin Dong Danping Guan Xiaoyun Hu Shujian Zhao Liang Li Lin Zhu Qiao Yan Junfeng Zhang Ke Zen Chen-Yu Zhang | 2010 | Cell Research2010，20，10： | 29 |
| 2 | Silicon photonic platforms for mid-infrared applications [Invited]显示文摘Silicon photonic integrated circuits for telecommunication and data centers have been well studied in the past decade, and now most related efforts have been progressing toward commercialization. Scaling up the silicon-oninsulator(SOI)-based device dimensions in order to extend the operation wavelength to the short mid-infrared(MIR) range(2–4 μm) is attracting research interest, owing to the host of potential applications in lab-on-chip sensors, free space communications, and much more. Other material systems and technology platforms, including silicon-on-silicon nitride, germanium-on-silicon, germanium-on-SOI, germanium-on-silicon nitride, sapphireon-silicon, Si Ge alloy-on-silicon, and aluminum nitride-on-insulator are explored as well in order to realize low-loss waveguide devices for different MIR wavelengths. In this paper, we will comprehensively review silicon photonics for MIR applications, with regard to the state-of-the-art achievements from various device demonstrations in different material platforms by various groups. We will then introduce in detail of our institute's research and development efforts on the MIR photonic platforms as one case study. Meanwhile, we will discuss the integration schemes along with remaining challenges in devices(e.g., light source) and integration. A few application-oriented examples will be examined to illustrate the issues needing a critical solution toward the final production path(e.g., gas sensors). Finally, we will provide our assessment of the outlook of potential futureresearch topics and engineering challenges along with opportunities. | TING HU BOWEI DONG XIANSHU LUO TSUNG-YANG LIOW JUNFENG SONG CHENGKUO LEE GUO-QIANG LO | 2017 | Photonics Research2017，5，5： | 13 |
| 3 | Driving forces of land use and land cover change (LUCC) in the Zoige Wetland, Qinghai-Tibetan Plateau显示文摘The Zoige Wetland is located in the northeastern Qinghai-Tibetan Plateau, which is highly sensitive to global environment change and human disturbance because of its high elevation and cold environment, thus, it's a hotspot for land use and land cover change (LUCC) research. We used Landsat MSS images from 1975, Landsat ETM images from 2000, and Landsat TM images from 1990 and 2005 to assess the LUCC in the study area, using GIS techniques, as well as topographic, vegetation, and soil maps combined with field investigations. The monitoring result shows that the study area's environment degraded rapidly between 1975 and 2005, including wetland shrinkage from 5,308 km 2 to 4,980 km 2 , sandy land expansion from 112 km 2 to 137 km 2 , forest land decreasing from 5,686 km 2 to 5,443 km 2 , and grassland degradation from 12,309 km 2 to 10,672 km 2 . According to the analysis of meteorological data and social-economic statistical data, we concluded that the LUCC in the Zoige Wetland was caused by both natural and anthropogenic factors, but human activities were primarily responsible for the observed LUCC, thereby, we suggest human behaviors must be adjusted to control environmental degradation. | GuangYin Hu ZhiBao Dong JunFeng Lu ChangZhen Yan | 2012 | Research in Cold and Arid Regions2012，4，5： | 7 |
| 4 | Incremental support vector machine algorithm based on multi-kernel learning显示文摘A new incremental support vector machine (SVM) algorithm is proposed which is based on multiple kernel learning.Through introducing multiple kernel learning into the SVM incremental learning,large scale data set learning problem can be solved effectively.Furthermore,different punishments are adopted in allusion to the training subset and the acquired support vectors,which may help to improve the performance of SVM.Simulation results indicate that the proposed algorithm can not only solve the model selection problem in SVM incremental learning,but also improve the classification or prediction precision. | Zhiyu Li Junfeng Zhang Shousong Hu | 2011 | Journal of Systems Engineering and Electronics2011，22，4： | 7 |
| 5 | Anaerobic BTEX degradation in soil bioaugmented with mixed consortia under nitrate reducing conditions显示文摘包括苯,甲苯,乙醇苯,和三二甲苯异构体, BTEX 的不同集中被增加进土壤样品在减少条件的硝酸盐下面由扩充改编 BTEX 的协会调查厌氧的降级潜力。所有 BTEX 底层能是厌氧的当起始的集中在在土壤的 100 mg/kg 下面时,联盟者简历在 70 d 以内降级了到非可检测的层次。甲苯比降级率的顺序是的任何另外的 BTEX 混合物,和 high-to-low 快被降级 toluene>ethylbenzene>m-xylene>o-xylene>benzene>p-xylene.Nitrite 与硝酸盐减小被积累,但是亚硝酸根的累积没在整个整个孵化在 BTEX 的降级上有禁止的效果。在土壤的土生土长的细菌能提高充实的混合细菌的 BTEX 简历降级能力。当六 BTEX 混合物同时是在土壤的现在时,他们有更低的起始的集中的降级上没有明显的禁止的效果。或者,苯,o二甲苯,和p二甲苯降级与 300 mg/kg.Higher BTEX 简历降级的更高起始的集中被禁止率与一个单身者的存在相比与钠醋酸盐的增加在土壤样品被观察 BTEX 底层,并且主要底层的刺激或 BTEX 简历降级的 cometabolic 改进的假设似乎可能。 | DOU Junfeng LIU Xiang HU Zhifeng | 2008 | Journal of Environmental Sciences2008，20，5： | 6 |
| 6 | Metal chalcogenide complex-mediated fabrication of Cu_2S film as counter electrode in quantum dot sensitized solar cells显示文摘Cu2S film onto FTO glass substrate was obtained to function as counter electrode for polysulfide redox reactions in CdS/CdSe co-sensitized solar cells by sintering after spraying a metal chalcogenide complex, N4H9Cu7S4 solution. Relative to Pt counter electrode, the Cu2S counter electrode provides greater electrocatalytic activity and lower charge transfer resistance. The prepared Cu2S counter electrode represented nanoflower-like porous film which was composed of Cu2S nanosheets on FTO and had a higher surface area and lower sheet resistance than that of sulfided brass Cu2S counter electrode. An energy conversion efficiency of 3.62% was achieved using the metal chalcogenide complex-mediated fabricated Cu2S counter electrode for CdS/CdSe co-sensitized solar cells under 1 sun, AM 1.5 illumination. | YU XueChao ZHU Jun LIU Feng WEI JunFeng HU LinHua DAI SongYuan | 2013 | Science China Chemistry2013，56，7： | 6 |
| 7 | A New Method of Wind Turbine Bearing Fault Diagnosis Based on Multi-Masking Empirical Mode Decomposition and Fuzzy C-Means Clustering显示文摘Based on Multi-Masking Empirical Mode Decomposition (MMEMD) and fuzzy c-means (FCM) clustering, a new method of wind turbine bearing fault diagnosis FCM-MMEMD is proposed, which can determine the fault accurately and timely. First, FCM clustering is employed to classify the data into different clusters, which helps to estimate whether there is a fault and how many fault types there are. If fault signals exist, the fault vibration signals are then demodulated and decomposed into different frequency bands by MMEMD in order to be analyzed further. In order to overcome the mode mixing defect of empirical mode decomposition (EMD), a novel method called MMEMD is proposed. It is an improvement to masking empirical mode decomposition (MEMD). By adding multi-masking signals to the signals to be decomposed in different levels, it can restrain low-frequency components from mixing in highfrequency components effectively in the sifting process and then suppress the mode mixing. It has the advantages of easy implementation and strong ability of suppressing modal mixing. The fault type is determined by Hilbert envelope finally. The results of simulation signal decomposition showed the high performance of MMEMD. Experiments of bearing fault diagnosis in wind turbine bearing fault diagnosis proved the validity and high accuracy of the new method. | Yongtao Hu Shuqing Zhang Anqi Jiang Liguo Zhang Wanlu Jiang Junfeng Li | 2019 | Chinese Journal of Mechanical Engineering2019，32，3： | 6 |
| 8 | Responses of zonal wind at -40°N to stratospheric sudden warming events in the stratosphere, mesosphere and lower thermosphere显示文摘Based on the data at^40°N at different longitudes during different stratospheric sudden warming(SSW)events,the responses of zonal winds in the stratosphere,mesosphere and lower thermosphere to SSWs are studied in this paper.The variations of zonal wind over Langfang,China(39.4°N,116.7°E)by MF radar and the modern era retrospective-analysis for research and applications(MERRA)wind data during 2010 and 2013 SSW and over Fort Collins,USA(41°N,105°W)by lidar and MERRA wind data during 2009 SSW are compared.Results show that the zonal wind at^40°N indeed respond to the SSWs while different specifics are found in different SSW events or at different locations.The zonal wind has significant anomalies during the SSWs.Over Langfang,before the onset of 2010 and 2013 SSW,the zonal wind reverses from eastward to westward below about 60–70 km and accelerates above this region,while westward wind prevails from 30 to 100 km after the onset of2010 SSW,and westward wind prevails in 30–60 and 85–100 km and eastward wind prevails in 60–85 km after the onset of2013 SSW.Over Fort Collins during 2009 SSW,eastward wind reverses to westward in 20–30 km before the onset while westward wind prevails in 20–30 and 60–97 km and eastward wind prevails in 30–60 and in 97–100 km after the onset.Moreover,simulations by the specified dynamics version of the whole atmosphere community climate model(SD-WACCM)are taken to explain different responding specifics of zonal wind to SSW events.It is found that the modulation of planetary wave(PW)plays the main role.Different phases of PWs would lead to the different zonal wind along with longitudes and the different amplitudes and phases in different SSW events can lead to the different zonal wind responses. | YANG JunFeng XIAO CunYing HU Xiong XU QingChen | 2017 | Science China(Technological Sciences)2017，60，6： | 5 |
| 9 | Research on the Surface Subsidence Monitoring Technology Based on Fiber Bragg Grating Sensing显示文摘 | Jinyu WANG Long JIANG Zengrong SUN Binxin HU Faxiang ZHANG Guangdong SONG Tongyu LIU Junfeng QI Longping ZHANG | 2017 | Photonic Sensors2017，7，1： | 5 |
| 10 | Preparation and characteristics of flexible all-organic thin-film field-effect transistor显示文摘All-organic thin-film field-effect transistor was prepared on flexible poly(ethylene-terephthalate) (PET) substrate. Poly(methyl-methacrylate) (PMMA) and pentacene are used as a dielectric layer and a semiconductor layer, respectively. The hole mobility of the transistor can reach 2.10×10-2 cm2/Vs, and the on/off current ratio was larger than 105. The performances of the transistor, when the substrate is cured under different radius, were also measured. It was found that the device performance did not change when the curly direction was vertical to the channel length direction and when the curly direction was parallel to the channel length direction with 3.67 cm curvature radius, the mobility of the device increased by more than 20% and the on/off ratio decreased more than one order. | QIU Yong, HU Yuanchuan, Dong Guifang, WANG Liduo, Xie Junfeng & MA Yaning Organic Optoelectronic Laboratory,Department of Chemistry, Tsinghua University, Beijing 100084, China (e-mail: qiuy@mail.Tsinghua.edu.cn) | 2003 | Chinese Science Bulletin2003，48，15： | 5 |
| 11 | Land use and land cover change and its driving forces in Maqu County, China in the past 25 years显示文摘LUCC;;driving forces;;Maqu County;;source region of the Yellow | JunFeng Lu ZhiBao Dong GuangYin Hu WenJin Li WanYin Luo MingLiang Tan | 2016 | Research in Cold and Arid Regions2016，8，5： | 4 |
| 12 | Characteristics of Abnormal Pressure Systems and Their Responses of Fluid in Huatugou Oil Field,Qaidam Basin显示文摘基于性质,构造和 Huatugou 油的反常压力系统的分发在 Qaidam 回答的核心样品,很好严峻的数据,和水库液体的全面学习盆被讨论。在压力系统和烃累积之间的关联被分析相应液体特征探讨。结果证明整个的 Huatugou 油领域有低形成压力和低液体精力;因此,烃是难的移居,它便于形成主要水库。学习水库,在 Xiayoushashan 形成定位了(N 21) 和 Shangganchaigou 形成(N 1) 是相对浅的并且有中等的孔和低渗透。他们分别地是有 0.61 和 0.72 的一个平均形成压力系数的反常低压的水库。根据压力系数和地热的异例, N 1 和 N 21 形成属于二个独立温度压力系统,和前者有稍微更高的精力。低压的分隔空间作为主要身体由远侧的工具条组成,专业版三角洲泥作为最高的边界,和岸和浅湖泥或海藻的墩作为底部边界。他们垂直地被重叠并且水平地 paralleled。形成水充满 Cl − 离子并且能与高咸度作为 CaCl 2 类型被分类,它显示反常低压的分隔空间处于好封上的状况并且为油和煤气的累积和保藏有益。 | CHEN Xiaozhi XU Hao TANG Dazhen ZHANG Junfeng HU Xiaolan TAO Shu CAI Yidong | 2009 | Acta Geologica Sinica(English Edition)2009，83，5： | 3 |
| 13 | Development of a Kind of Tartary Buckwheat Rice Wine显示文摘[Objectives]This study was conducted to improve the utilization of tartary buckwheat resources,enrich the varieties of rice wine products,and further promote the development of the rice wine industry.[Methods]With tartary buckwheat and glutinous rice as raw materials for mixed fermentation and sensory score as an evaluation indicator,the effects of four factors of material ratio,rice leaven addition,material-to-water ratio and fermentation time on the quality of tartary buckwheat rice wine were investigated.The optimal technological conditions of tartary buckwheat rice wine were determined by an orthogonal test.[Results]The optimal process conditions were as follows:the material ratio of 1∶0.2(g/g),the addition amount of rice leaven of 0.5%,the material to water ratio of 1∶0.4(g/ml),and the fermentation time of 72 h.The obtained tartary buckwheat rice wine product was light yellow,clear and bright,and tasted moderately sweet and sour.[Conclusions]The tartary buckwheat rice wine product has good color,fragrance and taste,and is a healthy drink that conforms to people s health concepts and is suitable for drinking. | Weixin WANG Juan XU Peng WU Ting HU Junfeng SHEN | 2021 | Agricultural Biotechnology2021，10，3： | 3 |
| 14 | Structure variety and its effects on biological activity of tea polysaccharides显示文摘Tea polysaccharides(TPSs),one of the major bioactive ingredients in tea,have been widely studied due to their variety of biological activities,including antioxidant,cancer prevention,hypoglycemia,anti-fatigue,anti-coagulant,anti-obesity and immunomodulatory effect.The biological effectiveness of TPSs has direct relation with their structures such as monosaccharide composition,molecular weight,glycosidic linkages,conformation and others,which can be influenced by tea materials,processing methods,extraction and purification procedures among others.Comparing to the study of tea polyphenols,the exploration of TPSs in structural elucidation and biofunctionality is very preliminary.Yet several factors affecting the structural change of TPSs have been studied and identified.Consequently,the variation of some TPS biological activity brought by the change of TPS structures has been evaluated and preliminary correlation of structure activity relationship of TPSs has been performed.Therefore,this review aims to serve as a summary research report regarding the influencing factors on TPSs structures and consequential effects on the biological activities of TPSs.We hope to provide updated information and systematic references for future study and functional food development of TPSs. | Ting Hu Peng Wu Jianfeng Zhan Weixin Wang Junfeng Shen Meiyan Wang Chi-Tang Ho Shiming Li | 2022 | Food Science and Human Wellness2022，11，3： | 2 |
| 15 | β-Elemene-loaded polymeric micelles intensify anti-carcinoma efficacy and alleviate side effects显示文摘β-Elemene is a volatile oil used for the treatment of cancer,but poor solubility,low bioavailability,and various adverse reactions limit its application.For amelio rating risks of the venous toxicity ofβ-elemene,intravenously injectable micelle ofβ-elemene was prepared using the thin-film hydration method.The results pointed out the micelles were uniformly spherical with about 20.96±0.1966 nm in average diameter and exhibited high entrapment efficiency(99.02%±0.88%).As revealed by drug release studies in vitro,β-elemene micelles had sustained drug release.Compared with freeβ-elemene,the micelles increased the drug cellular uptake and enhanced the anti-tumor effect in vitro through retarding cell cycle and inducing apoptosis.Meanwhile,the elevated se rum stability o fβ-elemene micelles implied less drug leakage and reduced toxicity.The wound healing and tube formation assay in vitro demonstrated the anti-metastasis and anti-angiogenesis effects ofβ-elemene micelles.Moreover,the pharmacokinetics study showed the AUC and T1/2 ofβ-elemene in micelle group were 1.79 and 1.62 times of that in free fi-elemene group,suggesting the circulation time ofβ-elemene in the blood had been prolonged.In addition,β-elemene micelles showed a favorable antitumor response compared with theβ-elemene solution on C26 colon cance r-bearing mice model.Local irritation study investigated in rabbits indicated that theβ-elemene micelles strikingly mitigated the irritation to the injection sites compared with freeβ-elemene.These results proved that the micelle could be a good candidate as an auspicious drug delivery system ofβ-elemene for the prospective clinical treatment of carcinoma. | Qiaoqiao Hu Lan Bai Zejiang Zhu Zhengying Su Peng Bai Minghai Tang Caixia Dou Junfeng Yan Rongsheng Tong Wuyu Zhang Lijuan Chen Lulu Cai | 2020 | Chinese Chemical Letters2020，31，3： | 2 |
| 16 | Study of the development road map of China’s renewable energy显示文摘Renewable energy (RE) has been attached high attention around the world due to its carbon-free and indigenous production in a sustainable way. China enjoys plenty of renewable energy resources, particularly the wind, solar, hydro- and biomass energy, which could be a sound basis for a large-scale exploitation. This report examines the current status of RE technology and industry, analyzes the challenges of promoting RE in China. In order to pave the way for a long-term development of RE, this paper outlines the basic principles and priorities for individual RE technology. In line with these, the paper puts forward the RE targets and further describes the RE road map by 2020, 2030 and extend to 2050, taking consideration of China’s RE resources, industrial basis and energy demand etc. At last, this paper provides some recommendations to ensure the achievements of the RE targets. | Huang Qili Li Junfeng Gao Hu | 2009 | Engineering Sciences2009，7，2： | 2 |
| 17 | The Oil-Bearing Pore Size Distribution of Lacustrine Shale from E2S42 Sub-Member in Damintun Sag,Liaohe Depression,Bohai Bay Basin,China显示文摘1 Introduction There is a set of organic rich shale at E22S4sub-member in damnintun sag.The organic material is typically type I.In recent years,breakthrough was obtained in shale oil exploration.The wettability of organic and inorganic pore is different.As a result,the mobility of oil in organic and inorganic pore is different.So it’s necessary to | CHEN Guohui LU Shuangfang LI Jinbu WANG Weiming TIAN Shansi SHAN Junfeng HU Yingjie MAO Jinli HAN Xia | 2015 | Acta Geologica Sinica(English Edition)2015，89，A01： | 2 |
| 18 | Development of Whole Potato Flour Fish Noodles显示文摘[Objectives] This study was conducted to prepare a kind of traditional aquatic food―fish noodles in Hubei Province by replacing some wheat flour with whole potato flour. [Methods] With whole potato flour, wheat flour and minced fish as main raw materials, the effects of the ratio of whole potato flour to minced fish and the addition amounts of sodium alginate, egg white, salt and ginger juice on the quality of whole potato flour fish noodles were studied. An orthogonal experiment was conducted to confirm the optimal technical formula of the whole potato flour fish noodles. [Results] The best formula of the whole potato flour fish noodles was whole potato flour 30 g, wheat flour 20 g, minced fish(grass carp) 50 g, salt 2.00 g, egg white 4.00 g, sodium alginate 2.00 g, and ginger juice 5.00 g. [Conclusions] The whole potato flour fish noodles prepared according to this formula are not only nutritious and taste good, but also have the advantages of easy and convenient eating and storage. This kind of fish noodle has good development prospects. | Weixin WANG Qingqin CHEN Peng WU Jianfeng ZHAN Ting HU Junfeng SHEN Yimin WANG | 2019 | Agricultural Biotechnology2019，8，6： | 2 |
| 19 | Original Sedimentary Pattern of an Inverted Basin:A Case Study from the Bozhong Depression,Offshore Bohai Bay Basin显示文摘The third member of Shahejie Formation(Sha-3 member; 42–38Ma of Eocene) in the Bozhong Depression,offshore Bohai Bay Basin was subject to multiple post-depositional modifications. The present structural framework of the Bozhong Depression,which is characterized by sags alternating with uplifts,does not reflect its original sedimentary pattern. Previous studies have not discussed the post-depositional modification of this succession,including the sedimentary pattern variations and the depositional geodynamic setting. This work determined the characteristics of the post-depositional modification and original sedimentary pattern of the Bozhong Depression through analysis of seismic data,well-log data and fission-track ages. The results demonstrate that the Shijiutuo rise,a major structural feature of the current basin,did not exist during the major depositional stage of the Sha-3 member,when the Qinnan sag was largely connected to the Bozhong sag to form a single contiguous deposition area within the basin. By contrast,the Shaleitian and Chengbei rises,located in the western part of the Bozhong Depression,have existed before the depositional period of the Eocene Sha-3 member; these features were manifested as syn-depositional tilted fault blocks,the uplifted footwall blocks of which provided sediments for the neighboring Shanan and Chengbei sags. The western part of the Bonan low rise,located in the southern part of the Bozhong Depression,did not experience uplifting during the depositional phase of the Eocene Sha-3 member. The Huanghekou sag was connected with the Bozhong sag in the western part of the Bozhong Depression. The original sedimentary boundary of the southern Miaoxi sag possibly extended eastward about 10 km and connected with the Bozhong sag at its northern part. The present-day Bodong low rise,which is bounded by the Tan–Lu fault zone,also formed after the depositional period of Eocene Sha-3 member. It is thus concluded that the Bozhong Depression formed a connected large-scale sub-basin during the depositional stage of the Eocene Sha-3 member. Several neighboring sags that are now separated by rises,including the Qinnan,Shanan,Chengbei,Huanghekou,Miaoxi and Bodong sags,formed a single contiguous depositional area during the Eocene. The significant differences between the present and original basin patter and framework provide valuable information for better understanding the history of basin inversion and its impact on related hydrocarbon-system evolution. | ZHAO Junfeng LIU Chiyang HUANG Lei MOUNTNEY Nigel HAN Shaojia LIU Peng HU Junhao | 2016 | Acta Geologica Sinica(English Edition)2016，90，6： | 2 |
| 20 | Assessment of sustainable energy potential of non-plantation biomass resources in China显示文摘 | Li Junfeng Hu Runqing Song Yanqing | 2005 | Biomass and Bioenergy2005，29，： | 1 |
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