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| 1 | SINS/GNSS integrated navigation system based on maximum versoria filter显示文摘In the missile-borne Strapdown Inertial Navigation System/Global Navigation Satellite System(SINS/GNSS)integrated navigation system,due to the factors such as the high dynamics,the signal blocking by obstacles,the signal intefereces,etc.,there always exist pulse interferences or measurement information interruptions in the satellite receiver,which make nonstationary measurement process.The traditional Kalman Filter(KF)can tackle the state estimation problem under Gaussian white noise,but its performance will be significantly reduced under nonGaussian noises.In order to deal with the non-Gaussian conditions in the actual missile-borne SINS/GNSS integrated navigation systems,a Maximum Versoria Criterion Extended Kalman Filter(MVC-EKF)algorithm is proposed based on the MVC and the idea of M-estimation,which assigns a smaller weight to the anomalous measurements so as to suppress the influence of anomalous measurements on the state estimation while maintaining a relatively low calculation cost.Finally,the integrated navigation simulation experiments prove the effectiveness and robustness of the proposed algorithm. | Chunhui ZHAO Zhenyu YANG Xiaoran CHENG Jinwen HU Xiaolei Hou | 2022 | Chinese Journal of Aeronautics2022，35，8： | 3 |
| 2 | Neodymium-doped Yttrium Aluminum Garnet Transparent Laser Ceramics Prepared by Co-precipitation Method显示文摘Transparent polycrystalline neodymium-doped yttrium aluminum garnet ceramics (Nd∶YAG) with better chemical stability, excellent optical and high temperature mechanical property is becoming a new laser host material. The Nd∶YAG precursor powders with loosely dispersed, slightly agglomerated and YAG cubic crystal phase were synthesized at 1100 ℃ by the co-precipitation method combined with the reverse strike, using Nd2O3, Y2O3, Al(NO3)3·9H2O and NH4HCO3 as raw materials, (NH4)2SO4 as electrical stabilizer, TEOS as sintering additive. The Nd∶YAG transparent ceramics were fabricated after being sintered at 1700 ℃ in vacuum for 5 h. The Nd∶YAG ceramic materials were characterized by the TG-DTA, XRD, FT-IR, TEM, FT-PL and FEG-ESEM. The results show that the precursor powders are amorphous at 800 ℃, the large amount YAlO3(YAP) and tiny amout Y3Al5O 12(YAG) appear when the calcination temperature is 890 ℃ and the YAP hexagonal crystal phase transforms to YAG cubic crystal phase at 1012 ℃. There are agglomerations in the precursor powders resulting from the high calcination temperature and the agglomerates link together, but as a whole the particles distribute homogeneously. The lasing wavelength of (Nd 0.01Y 0.99)3Al5O 12 transparent ceramics is 1.065 μm and there exists a slight red-shift compared to the single crystal with the same chemical composition. With the optical wavelength increasing, the transmittance of (Nd 0.01Y 0.99)3Al5O 12 raises gradually and the optical transmittance is about 45% in the visible light and 58% in the infrared light. | Su Chunhui Song Qiong Zhang Huashan Zhang Hongbo Hou Zhaoxia Shao Jing | 2006 | Journal of Rare Earths2006，24，1： | 2 |
| 3 | Study on crystallization and microstructure of Li_2O-Al_2O_3-SiO_2 glass ceramics显示文摘 | Zhaoxia Hou Yongming Zhang Huashan Zhang Hongbo Zhang Jing Shao Chunhui Su | 2006 | Journal of University of Science and Technology Beijing2006，13，6： | 2 |
| 4 | Baf60b-mediated ATM-p53 activation blocks cell identity conversion by sensing chromatin opening显示文摘由系特定的抄写因素的表示的系变换是改变那的 epigenetic 的进程有低效率。一个房间由抵抗系变换的机制大部分是未知的。使用肝特定的抄写因素 Foxa3, Hnf1 和 Gata4 (3TF ) 在老鼠成纤维细胞导致肝的变换,我们证明 3TF 导致了 ATM-p53 小径的强壮的激活,它导致了增长拘捕和房间死亡,和它进一步阻止了肝的变换。尤其是, ATM 激活,独立于 DNA 损坏,对染色质在肝的变换期间开作出回应。由在肝的变换期间描绘早分子的事件,我们发现了那 Baf60b,改变建筑群的 SWI/SNF 染色质的一个成员,连接染色质洞到由便于 ATM 招募到肝的基因 loci 的一块面板的开的染色质区域的 ATM 激活。这些调查结果由在察觉到揭示 ATM-p53 小径的功能使细胞的回答清楚些到系变换染色质洞。 | Shuyi Ji Linying Zhu Yimeng Gao Xiaoran Zhang Yupeng Yan Jin Cen Rongxia Li Rong Zeng Lujian Liao Chunhui Hou Yawei Gao Shaorong Gao Gang Wei Lijian Hui | 2017 | Cell Research2017，27，5： | 2 |
| 5 | Epigenetics of β-globin gene regulation显示文摘 | Kiefer Christine M Chunhui Hou Little Jane A | 2008 | Mutation Research2008，647，： | 1 |
| 6 | Matrine upregulates the cell cycle protein E2F-1 and triggers apoptosis via the mitochondrial pathway in K562 cells显示文摘 | Hua Jiang ChunHui Hou ShuBing Zhang HengYue Xie WeiYing Zhou QiHuang Jin XiaoDong Cheng RuoLan Qian XueJun Zhang | 2007 | European Journal of Pharmacology2007，，2： | 1 |
| 7 | Test set optimization using cultural particle swarm optimization显示文摘 | Hou Yanli Hu Jiawei Zhao Chunhui | 2007 | Journal of Harbin Engineering University2007，，： | 1 |
| 8 | Genome-wide identification of functional enhancers and their potential roles in pig breeding显示文摘Background:The pig is an economically important livestock species and is a widely applied large animal model in medical research.Enhancers are critical regulatory elements that have fundamental functions in evolution,development and disease.Genome-wide quantification of functional enhancers in the pig is needed.Results:We performed self-transcribing active regulatory region sequencing(STARR-seq)in the porcine kidney epithelial PK15 and testicular ST cell lines,and reliably identified 2576 functional enhancers.Most of these enhancers were located in repetitive sequences and were enriched within silent and lowly expressed genes.Enhancers poorly overlapped with chromatin accessibility regions and were highly enriched in chromatin with the repressive histone modification H3K9me3,which is different from predicted pig enhancers detected using ChIP-seq for H3K27ac or/and H3K4me1 modified histones.This suggests that most pig enhancers identified with STARR-seq are endogenously repressed at the chromatin level and may function during cell type-specific development or at specific developmental stages.Additionally,the PPP3CA gene is associated with the loin muscle area trait and the QKI gene is associated with alkaline phosphatase activity that may be regulated by distal functional enhancers.Conclusions:In summary,we generated the first functional enhancer map in PK15 and ST cells for the pig genome and highlight its potential roles in pig breeding. | Yinqiao Wu Yuedong Zhang Hang Liu Yun Gao Yuyan Liu Ling Chen Lu Liu David M.Irwin Chunhui Hou Zhongyin Zhou Yaping Zhang | 2022 | Journal of Animal Science and Biotechnology2022，13，6： | 1 |
| 9 | Preparation and characterization of zinc aluminosilicate transparent glass-ceramics显示文摘 | Hou Zhaoxia Ph D Zhang Yongming Zhang Hongbo Su Chunhui Ph D | 2006 | Journal of Wuhan University of Technology - Mater Sci Ed2006，，1： | 1 |
| 10 | Genome-wide analysis of aberrantly expressed circulating miRNAs in patients with coal workers’ pneumoconiosis显示文摘 | Li Guo Xiaoming Ji Sheng Yang Zhiguo Hou Chen Luo Jingjing Fan Chunhui Ni Feng Chen | 2013 | Molecular Biology Reports2013，，5： | 1 |
| 11 | Understanding Miocene Climate Evolution in Northeastern Tibet: Stable Carbon and Oxygen Isotope Records from the Western Tianshui Basin, China显示文摘To investigate climate evolution during the Miocene, especially during the Middle Miocene climate transition on the northeastern Tibetan Plateau, stable oxygen and carbon isotopes of carbonates from a 288-m-thick lacustrine-fluvial sediment sequence covering the period from 17.1 to 6.1 Ma from Tianshui Basin, China, were analyzed. The relatively low stable oxygen isotope values indicate the prevalence of wet climate conditions during the period of 17.1–13.6 Ma, an interval corresponding to the well-known Middle Miocene Climate Optimum. The interval between 13.6 and 11.0 Ma(i.e., the late Middle Miocene) is marked by a progressive increase in the δ18O values, indicative of a decrease in precipitation, probably linked to the expansion of the East Antarctic Ice Sheet and global cooling since about 14 Ma. The climate in the study area continued to get drier as shown by the enrichment of the heavy oxygen isotope from 11 Ma. We attribute these stepwise climatic changes as revealed by our carbonate δ18O record from the northeastern Tibetan Plateau to the sustained global cooling that may have reduced moist transport to Central Asia, which in turn led to a permanent aridification. | Zhanfang Hou Jijun Li Chunhui Song Jun Zhang Zhengchuang Hui Shiyue Chen Feng Xian | 2014 | Journal of Earth Science2014，25，2： | 1 |
| 12 | Comparative tribological behavior of friction composites containing natural graphite and expanded graphite显示文摘In this study, expanded graphite and natural graphite were introduced into resin-based friction materials, and the tribological behavior of the composites was investigated. The tribo-performance of the two friction composites was evaluated using a constant speed friction tester. The results showed that the expanded graphite composite (EGC) displayed better lubricity in both the fading and the recovery processes. The wear rate of the EGC decreased by 22.43%more than that of the natural graphite composite (NGC). In the fading process, and the EGC enhanced the stability of the coefficient of friction. The recovery maintenance rate of the NGC was 4.66% higher than that of the EGC. It can be concluded that expanded graphite plays an important role in the formation of a stable contact plateau and can effectively reduce the wear. | Hongyun JIN Keke ZHOU Zhengjia JI Xiaocong TIAN Ying CHEN Luhua LU Yazhou REN Chunhui XU Shanshan DUAN Jiangyu LI Shu-en HOU | 2020 | Friction2020，8，4： | 0 |
| 13 | Interactions between HMG proteins (HMG1/2 and HMG14/17) and human ε-globin gene promoter (ε-promoter)显示文摘High mobility group (HMG) proteins are abundant non-histone proteins in the nuclei of eukaryocytes. It has been shown that HMG proteins may play important roles in the structure and function of chromatin. In the present study, the binding of HMG proteins (HMG1/2 and HMG14/17) to the human e-globin gene promoter (e-promo-ter, -177-+1 bp) has been examined by using both the in vitro nucleosome reconstitution and the electrophoresis mobility shift assay (EMSA). We found that HMG1/2 proteins could bind to the naked e-promoter DNA, however, HMG14/17 could not. Using the in vitro nucleosome reconstitution, we revealed that HMG14/17 could bind to the mononucleosome reconstituted in vitro with E-promoter, while HMG1/2 could not. Those results indicate that the binding of HMG proteins to e-promoter is dynamic as the nucleosome assembling and disassembling. We speculated that this selective binding of HMG proteins to e-promoter might play a critical role in the regulation of e-globin gene expression. | Chunhui Hou Jian Huang Shubing Zhang Ruolan Qian | 2002 | Chinese Science Bulletin2002，47，18： | 0 |
| 14 | Global Quantitative Mapping of Enhancers in Rice by STARR-seq显示文摘Enhancers activate transcription in a distance-,orientation-,and position-independent manner,which makes them difficult to be identified. Self-transcribing active regulatory region sequencing (STARR-seq) measures the enhancer activity of millions of DNA fragments in parallel. Here we used STARR-seq to generate a quantitative global map of rice enhancers. Most enhancers were mapped within genes,especially at the 5' untranslated regions (5'UTR) and in coding sequences. Enhancers were also frequently mapped proximal to silent and lowly-expressed genes in transposable element (TE)-rich regions. Analysis of the epigenetic features of enhancers at their endogenous loci revealed that most enhancers do not co-localize with DNase I hypersensitive sites (DHSs) and lack the enhancer mark of histone modification H3K4me1. Clustering analysis of enhancers according to their epigenetic marks revealed that about 40%of identified enhancers car-ried one or more epigenetic marks. Repressive H3K27me3 was frequently enriched with positive marks,H3K4me3 and/or H3K27ac,which together label enhancers. Intergenic enhancers were also predicted based on the location of DHS regions relative to genes,which overlap poorly with STARR-seq enhancers. In summary,we quantitatively identified enhancers by functional analysis in the genome of rice,an important model plant. This work provides a valuable resource for further mechanistic studies in different biological contexts. | Jialei Sun Na He Longjian Niu Yingzhang Huang Wei Shen Yuedong Zhang Li Li Chunhui Hou | 2019 | Genomics, Proteomics & Bioinformatics2019，17，2： | 0 |
| 15 | PHB介导的HIRA复合物调控人胚胎干细胞的表观--代谢环路显示文摘文章简介染色质地貌和细胞代谢对细胞命运决定有着重要的作用,但人们对它们之间的相互作用却了解甚少。课题组运用基因组范围的si RNA筛选,发现PHB对于维持人胚胎干细胞的自我更新具有重要的作用。 | Huanhuan Li Ping Lai Jinping Jia Yawei Song Qing Xia Kaimeng Huang Na He Wangfang Ping Jiayu Chen Zhongzhou Yang Jiao Li Mingze Yao Xiaotao Dong Jicheng Zhao Chunhui Hou Miguel A.Esteban Shaorong Gao Duanqing Pei Andrew P.Hutchins 姚红杰 Zhexin Zhu Chunliang Li Yanwu Zeng Jianyi Ding Zepeng Qu Junjie Gu Laixiang Ge Fan Tang Xin Huang Chenlin Zhou Ping Wang Deyou Zheng 金颖 | 2018 | 科学新闻2018，0，4： | 0 |
| 16 | RNA解旋酶DDX5通过miRNA调控RYBP依赖和非依赖于PRC1的双重功能而抑制体细胞重编程显示文摘RNA结合蛋白除了调控细胞内动态平衡的功能外,RNA结合蛋白在谱系分化和维持细胞身份中扮演着重要角色。 | Huanhuan Li Ping Lai Jinping Jia Yawei Song Qing Xia Kaimeng Huang Na He Wangfang Ping Jiayu Chen Zhongzhou Yang Jiao Li Mingze Yao Xiaotao Dong Jicheng Zhao Chunhui Hou Miguel A.Esteban Shaorong Gao Duanqing Pei Andrew P.Hutchins 姚红杰 | 2018 | 科学新闻2018，0，4： | 0 |
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