5篇
您的检索式：作者名="Chunwen Pu"
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| 1 | Sources and distribution of polycyclic aromatic hydrocarbons of different glaciers over the Tibetan Plateau显示文摘Twenty snow samples were collected from the Qiyi glacier in Qilian Mountains,the Yuzhufeng glacier in eastern Kunlun Mountains,the Xiaodongkemadi glacier in Tanggula Mountains,and the Gurenhekou glacier in Nyainqêntanglha Range over the Tibetan Plateau.The concentration and distribution features of sixteen priority Polycyclic Aromatic Hydrocarbons (PAHs) were determined by gas chromatography equipped with a mass spectrometry detector (GC-MS).The sources of these PAHs were explored as well.Our results indicated that the average concentrations of PAHs in snow were in the range of 20.45 60.57 ng/L.Maximum PAHs levels were found in the YZF glacier andminimum in the XDKMD glacier.However,no apparent regional distribution pattern of PAHs was found in the glaciers over the Tibetan Plateau.Moreover,the 2 4 ring low molecular weight PAHs predominated in snow samples and the concentrations of phenanthrene was the highest.Integrated factor analysis and isomer pair ratios suggested that PAHs of glaciers over the Tibetan Plateau were derived from low temperature combustion of coal and biomass,and partially from the exhaust gas of locomotives.Air mass back trajectory indicated that organic compounds detected in snowpit of these four glaciers,in the period of time they represented,mainly came from Central Asia and the arid area of Northwest China by westerly wind circulation. | LI QuanLian WANG NingLian WU XiaoBo PU JianChen HE JianQiao ZHANG ChunWen | 2011 | Science China Earth Sciences2011，54，8： | 5 |
| 2 | Change of Cytokines in Chronic Hepatitis B Patients and HBeAg are Positively Correlated with HBV RNA, Based on Real-world Study显示文摘Background and Aims:The natural course of chronic hepatitis B virus(HBV)infection is widely studied;however,follow-up studies of the same patients are scanty.Here,we studied the dynamic changes of serum HBV RNA and cytokines in hepatitis B virus e antigen(HBeAg)-positive patients treated with entecavir(ETV)to explore the relationship between the HBV serum viral nucleic acids and host immunity.Methods:Thirty-three chronic hepatitis B patients who are HBeAg-positive,with high virus load(HBV DNA>20,000 IU/mL),and received standard nucleos(t)ide analogue(NA)antiviral therapy(ETV)for more than 48 weeks were included.The serum levels of HBV nucleic acids and selected cytokines were measured at 0,12,24,and 48 weeks respectively.Results:Serum HBV RNA could still be detected while serum HBV DNA had fallen below the detection limit in patients treated with ETV.There was a strong positive correlation between HBV RNA and HBeAg,with a concomitant decrease in the secretion of cytokines from type 1 helper T(Th1)/type 2 helper T(Th2)/interleukin(IL)-17 producing T(Th17)cells.IL-4 and IL-10 were the main cytokines negatively associated with serum HBV RNA.Conclusions:HBeAg can be used to reflect the load of HBV RNA indirectly,because serum HBV RNA has not been widely used in clinical practice.Meanwhile,serum IL-4 and IL-10 might be explored in combination with HBV RNA in guiding future clinical antiviral therapy. | Qiqi Zhang Hui Huang Aijun Sun Chunyan Liu Zhidong Wang Feifan Shi Wei Duan Xueying Sun Qi Wang Ping Sun Chunwen Pu Yong Zhang | 2022 | Journal of Clinical and Translational Hepatology2022，10，3： | 1 |
| 3 | Inflammation and cancer stem cells显示文摘 | Sarah Shigdar Yong Li Santanu Bhattacharya Michael O’Connor Chunwen Pu Jia Lin Tao Wang Dongxi Xiang Lingxue Kong Ming Q. Wei Yimin Zhu Shufeng Zhou Wei Duan | 2014 | Cancer Letters2014，，2： | 1 |
| 4 | Cancer stem cells: A contentious hypothesis now moving forward显示文摘 | Michael L. O’Connor Dongxi Xiang Sarah Shigdar Joanna Macdonald Yong Li Tao Wang Chunwen Pu Zhidong Wang Liang Qiao Wei Duan | 2013 | Cancer Letters2013，，： | 1 |
| 5 | Inflammation and cancer stem cells显示文摘 | Sarah Shigdar Yong Li Santanu Bhattacharya Michael O’Connor Chunwen Pu Jia Lin Tao Wang Dongxi Xiang Lingxue Kong Ming Q. Wei Yimin Zhu Shufeng Zhou Wei Duan | 2014 | Cancer Letters2014，，2： | 1 |
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